PubRank

Falk Nimmerjahn

Author PubWeight™ 92.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 2006 8.13
2 Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat Rev Immunol 2013 4.33
3 Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest 2012 4.31
4 Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science 2008 4.11
5 Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol 2010 2.70
6 Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate. J Immunol 2010 2.38
7 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity 2012 2.06
8 Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation. J Exp Med 2009 2.03
9 Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J Exp Med 2006 2.00
10 The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat Immunol 2004 1.95
11 Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. Nat Med 2012 1.93
12 Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy. J Exp Med 2006 1.80
13 Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. J Clin Invest 2006 1.76
14 Stringent doxycycline-dependent control of gene activities using an episomal one-vector system. Nucleic Acids Res 2005 1.74
15 Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Ann Rheum Dis 2012 1.58
16 Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci U S A 2010 1.50
17 Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis. Arthritis Rheumatol 2014 1.48
18 In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proc Natl Acad Sci U S A 2008 1.44
19 Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PLoS One 2008 1.37
20 Impact of immune complex size and glycosylation on IgG binding to human FcγRs. J Immunol 2013 1.36
21 Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy. Proc Natl Acad Sci U S A 2009 1.35
22 Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis. Eur J Immunol 2007 1.32
23 A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques. J Virol 2012 1.29
24 Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo. Immunity 2011 1.26
25 Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice. Proc Natl Acad Sci U S A 2013 1.14
26 The role of sialic acid as a modulator of the anti-inflammatory activity of IgG. Semin Immunopathol 2012 1.11
27 Impact of differential glycosylation on IgG activity. Adv Exp Med Biol 2011 1.11
28 Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV. J Immunol 2008 1.08
29 The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo. Curr Opin Organ Transplant 2011 1.08
30 Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets. Exp Hematol 2008 1.06
31 Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol 2008 1.04
32 Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions. J Immunol 2008 1.02
33 IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1. Eur J Immunol 2012 1.01
34 Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo. Proc Natl Acad Sci U S A 2011 1.01
35 Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. Arthritis Rheum 2009 1.00
36 Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. J Immunol 2008 1.00
37 Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. J Virol 2003 0.99
38 Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells. Eur J Immunol 2004 0.99
39 Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation. J Immunol 2005 0.99
40 Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export. Eur J Immunol 2008 0.95
41 Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. Eur J Immunol 2009 0.94
42 Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum 2010 0.93
43 Mechanisms of IVIG efficacy in chronic inflammatory demyelinating polyneuropathy. J Clin Immunol 2010 0.92
44 Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury. J Pathol 2012 0.91
45 Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. J Clin Invest 2015 0.91
46 Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A. Circ Res 2012 0.91
47 Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo. Eur J Immunol 2014 0.91
48 Of mice and men: the need for humanized mouse models to study human IgG activity in vivo. J Clin Immunol 2012 0.90
49 NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases. Proc Natl Acad Sci U S A 2013 0.90
50 B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo. Eur J Immunol 2012 0.88
51 Mechanisms of action of intravenous immunoglobulins. Expert Rev Clin Immunol 2010 0.86
52 FcγRIIB: a modulator of cell activation and humoral tolerance. Expert Rev Clin Immunol 2012 0.86
53 Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis. Arthritis Rheum 2009 0.86
54 B cells are critical for autoimmune pathology in Scurfy mice. Proc Natl Acad Sci U S A 2013 0.85
55 Impact of a three amino acid deletion in the CH2 domain of murine IgG1 on Fc-associated effector functions. J Immunol 2008 0.84
56 The role of Fc receptors and complement in autoimmunity. Autoimmun Rev 2012 0.83
57 Nucleoprotein-specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcγR. Eur J Immunol 2013 0.83
58 Low level of FcγRIII expression on murine natural killer cells. Immunol Lett 2012 0.82
59 TLR7/9-mediated monocytosis and maturation of Gr-1(hi) inflammatory monocytes towards Gr-1(lo) resting monocytes implicated in murine lupus. J Autoimmun 2011 0.81
60 Fcγ receptor deficiency attenuates diabetic nephropathy. J Am Soc Nephrol 2012 0.81
61 Immune regulation: FcgammaRIIB--regulating the balance between protective and autoreactive immune responses. Immunol Cell Biol 2008 0.80
62 Deletion of activating Fcgamma receptors does not confer protection in murine cryoglobulinemia-associated membranoproliferative glomerulonephritis. Am J Pathol 2009 0.79
63 STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient. J Leukoc Biol 2010 0.78
64 Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells. Immunol Lett 2010 0.77
65 B cell expression of the inhibitory Fc gamma receptor is unchanged in early MS. J Neuroimmunol 2010 0.77
66 Targeting B cells and autoantibodies in the therapy of autoimmune diseases. Semin Immunopathol 2014 0.77
67 Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G. Curr Top Microbiol Immunol 2014 0.76
68 B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis. Eur J Immunol 2014 0.76
69 High amounts of specific antibodies are produced upon antigen stimulation during adaptive immune responses. Preface. Curr Top Microbiol Immunol 2014 0.75
70 The role of Fcgamma receptors in murine autoimmune thrombocytopenia. Ann Hematol 2010 0.75
71 Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. Nat Immunol 2017 0.75