Published in J Immunol on March 18, 2013
Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies. Cancer Cell (2014) 1.55
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss. Nat Commun (2015) 1.50
HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. J Virol (2014) 1.29
Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. Immunity (2015) 1.23
Structural determinants of unique properties of human IgG4-Fc. J Mol Biol (2013) 1.09
The role of Fc-FcγR interactions in IgG-mediated microbial neutralization. J Exp Med (2015) 1.08
Antigen cross-presentation of immune complexes. Front Immunol (2014) 0.99
The Structural Role of Antibody N-Glycosylation in Receptor Interactions. Structure (2015) 0.95
Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding. Proc Natl Acad Sci U S A (2015) 0.94
The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor. MAbs (2016) 0.92
Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura. Haematologica (2013) 0.92
Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. J Clin Invest (2015) 0.91
Highly parallel characterization of IgG Fc binding interactions. MAbs (2014) 0.89
Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity. MAbs (2013) 0.88
Restricted motion of the conserved immunoglobulin G1 N-glycan is essential for efficient FcγRIIIa binding. Structure (2014) 0.86
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions. MAbs (2015) 0.85
CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity. Semin Immunopathol (2014) 0.84
Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants. PLoS One (2015) 0.83
The role of Fc receptors in HIV prevention and therapy. Immunol Rev (2015) 0.81
A perspective on the structure and receptor binding properties of immunoglobulin G Fc. Biochemistry (2015) 0.80
IgG4 Characteristics and Functions in Cancer Immunity. Curr Allergy Asthma Rep (2016) 0.79
Isotype Diversification of IgG Antibodies to HIV Gag Proteins as a Therapeutic Vaccination Strategy for HIV Infection. Vaccines (Basel) (2013) 0.78
Influence of immunoglobulin isotype on therapeutic antibody function. Blood (2016) 0.78
Intramolecular N-glycan/polypeptide interactions observed at multiple N-glycan remodeling steps through [(13)C,(15)N]-N-acetylglucosamine labeling of immunoglobulin G1. Biochemistry (2014) 0.78
Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid. J Neuroinflammation (2015) 0.78
Targeting B cells and autoantibodies in the therapy of autoimmune diseases. Semin Immunopathol (2014) 0.77
IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcγRI. MAbs (2014) 0.77
FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis. Proc Natl Acad Sci U S A (2014) 0.77
Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway. MBio (2016) 0.76
Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein. AIDS Res Hum Retroviruses (2015) 0.76
Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications. Sci Rep (2015) 0.76
EndoS reduces the pathogenicity of anti-mCOL7 IgG through reduced binding of immune complexes to neutrophils. PLoS One (2014) 0.75
Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor. Sci Rep (2017) 0.75
Label-free detection of immune complexes with myeloid cells. Clin Exp Immunol (2016) 0.75
Fc-Galactosylation of Human Immunoglobulin Gamma Isotypes Improves C1q Binding and Enhances Complement-Dependent Cytotoxicity. Front Immunol (2017) 0.75
Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes. PLoS One (2016) 0.75
CP40 from Corynebacterium pseudotuberculosis is an endo-β-N-acetylglucosaminidase. BMC Microbiol (2016) 0.75
The role of Fc-FcγR interactions in the anti-tumor activity of therapeutic antibodies. Immunol Cell Biol (2016) 0.75
Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB. J Clin Immunol (2016) 0.75
Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon. ACS Chem Biol (2016) 0.75
Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity. MAbs (2016) 0.75
Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors. J Biol Chem (2017) 0.75
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. Nat Immunol (2017) 0.75
Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering. Sci Rep (2017) 0.75
Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science (2006) 8.13
Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat Rev Immunol (2013) 4.33
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest (2012) 4.31
Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science (2008) 4.11
A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27
Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol (2010) 2.70
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate. J Immunol (2010) 2.38
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity (2012) 2.06
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation. J Exp Med (2009) 2.03
Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J Exp Med (2006) 2.00
The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat Immunol (2004) 1.95
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. Nat Med (2012) 1.93
Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy. J Exp Med (2006) 1.80
Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. J Clin Invest (2006) 1.76
Stringent doxycycline-dependent control of gene activities using an episomal one-vector system. Nucleic Acids Res (2005) 1.74
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest (2013) 1.60
Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Ann Rheum Dis (2012) 1.58
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci U S A (2010) 1.50
Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis. Arthritis Rheumatol (2014) 1.48
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proc Natl Acad Sci U S A (2008) 1.44
Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PLoS One (2008) 1.37
Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy. Proc Natl Acad Sci U S A (2009) 1.35
Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis. Eur J Immunol (2007) 1.32
Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo. Immunity (2011) 1.26
Crystal structure of sialylated IgG Fc: implications for the mechanism of intravenous immunoglobulin therapy. Proc Natl Acad Sci U S A (2013) 1.17
Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice. Proc Natl Acad Sci U S A (2013) 1.14
Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis. J Am Chem Soc (2012) 1.12
The role of sialic acid as a modulator of the anti-inflammatory activity of IgG. Semin Immunopathol (2012) 1.11
Impact of differential glycosylation on IgG activity. Adv Exp Med Biol (2011) 1.11
Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV. J Immunol (2008) 1.08
The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo. Curr Opin Organ Transplant (2011) 1.08
Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets. Exp Hematol (2008) 1.06
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol (2008) 1.04
Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions. J Immunol (2008) 1.02
IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1. Eur J Immunol (2012) 1.01
Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo. Proc Natl Acad Sci U S A (2011) 1.01
Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. Arthritis Rheum (2009) 1.00
Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. J Immunol (2008) 1.00
Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. J Virol (2003) 0.99
Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation. J Immunol (2005) 0.99
Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells. Eur J Immunol (2004) 0.99
Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export. Eur J Immunol (2008) 0.95
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. Eur J Immunol (2009) 0.94
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum (2010) 0.93
Mechanisms of IVIG efficacy in chronic inflammatory demyelinating polyneuropathy. J Clin Immunol (2010) 0.92
Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury. J Pathol (2012) 0.91
Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. J Clin Invest (2015) 0.91
Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo. Eur J Immunol (2014) 0.91
A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation. Oncotarget (2014) 0.91
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A. Circ Res (2012) 0.91
Of mice and men: the need for humanized mouse models to study human IgG activity in vivo. J Clin Immunol (2012) 0.90
NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases. Proc Natl Acad Sci U S A (2013) 0.90
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function. AIDS (2014) 0.88
B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo. Eur J Immunol (2012) 0.88
Th1 and Th2 cytokine profiles induced by hepatitis C virus F protein in peripheral blood mononuclear cells from chronic hepatitis C patients. Immunol Lett (2013) 0.86
Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis. Arthritis Rheum (2009) 0.86
FcγRIIB: a modulator of cell activation and humoral tolerance. Expert Rev Clin Immunol (2012) 0.86
Mechanisms of action of intravenous immunoglobulins. Expert Rev Clin Immunol (2010) 0.86
A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. FASEB J (2008) 0.86
B cells are critical for autoimmune pathology in Scurfy mice. Proc Natl Acad Sci U S A (2013) 0.85
Impact of a three amino acid deletion in the CH2 domain of murine IgG1 on Fc-associated effector functions. J Immunol (2008) 0.84
Nucleoprotein-specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcγR. Eur J Immunol (2013) 0.83
The role of Fc receptors and complement in autoimmunity. Autoimmun Rev (2012) 0.83
Low level of FcγRIII expression on murine natural killer cells. Immunol Lett (2012) 0.82
Structural insights into the neutralization mechanism of monoclonal antibody 6C2 against ricin. J Biol Chem (2013) 0.82
Examining of athermal effects in microwave-induced glucose/glycine reaction and degradation of polysaccharide from Porphyra yezoensis. Carbohydr Polym (2013) 0.81
TLR7/9-mediated monocytosis and maturation of Gr-1(hi) inflammatory monocytes towards Gr-1(lo) resting monocytes implicated in murine lupus. J Autoimmun (2011) 0.81
Fcγ receptor deficiency attenuates diabetic nephropathy. J Am Soc Nephrol (2012) 0.81
Immune regulation: FcgammaRIIB--regulating the balance between protective and autoreactive immune responses. Immunol Cell Biol (2008) 0.80
Deletion of activating Fcgamma receptors does not confer protection in murine cryoglobulinemia-associated membranoproliferative glomerulonephritis. Am J Pathol (2009) 0.79
STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient. J Leukoc Biol (2010) 0.78
Pretreatment of defatted wheat germ proteins (by-products of flour mill industry) using ultrasonic horn and bath reactors: effect on structure and preparation of ACE-inhibitory peptides. Ultrason Sonochem (2013) 0.78
Effect of two kinds of different combined oral contraceptives use on bone mineral density in adolescent women. Contraception (2012) 0.77
Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells. Immunol Lett (2010) 0.77
B cell expression of the inhibitory Fc gamma receptor is unchanged in early MS. J Neuroimmunol (2010) 0.77
Targeting B cells and autoantibodies in the therapy of autoimmune diseases. Semin Immunopathol (2014) 0.77
Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G. Curr Top Microbiol Immunol (2014) 0.76
B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis. Eur J Immunol (2014) 0.76
High amounts of specific antibodies are produced upon antigen stimulation during adaptive immune responses. Preface. Curr Top Microbiol Immunol (2014) 0.75
[Antimicrobial resistance profiles and genetic diversity of bovine staphylococcus aureus isolated in 5 provinces of China in 2013]. Zhonghua Yu Fang Yi Xue Za Zhi (2014) 0.75
Construction of novel bifunctional chimeric proteins possessing antitumor and thrombolytic activities. J Microbiol Biotechnol (2012) 0.75
The role of Fcgamma receptors in murine autoimmune thrombocytopenia. Ann Hematol (2010) 0.75
Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. Nat Immunol (2017) 0.75