Published in Invest Ophthalmol Vis Sci on December 05, 2008
Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages. J Exp Med (2011) 1.80
Neuroprotective effects of intravitreal mesenchymal stem cell transplantation in experimental glaucoma. Invest Ophthalmol Vis Sci (2009) 1.79
Mechanisms of retinal ganglion cell injury and defense in glaucoma. Exp Eye Res (2010) 1.44
Glaucoma: genes, phenotypes, and new directions for therapy. J Clin Invest (2010) 1.39
CNTF and retina. Prog Retin Eye Res (2011) 1.34
Retinal ganglion cell loss in a rat ocular hypertension model is sectorial and involves early optic nerve axon loss. Invest Ophthalmol Vis Sci (2011) 1.24
Pathophysiology of human glaucomatous optic nerve damage: insights from rodent models of glaucoma. Exp Eye Res (2010) 1.13
Transplantation of BDNF-secreting mesenchymal stem cells provides neuroprotection in chronically hypertensive rat eyes. Invest Ophthalmol Vis Sci (2011) 1.06
Ciliary neurotrophic factor induces genes associated with inflammation and gliosis in the retina: a gene profiling study of flow-sorted, Müller cells. PLoS One (2011) 1.01
Increased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma. Mol Vis (2010) 1.00
Intrinsic axonal degeneration pathways are critical for glaucomatous damage. Exp Neurol (2012) 0.93
Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma? Exp Eye Res (2009) 0.89
Inducible nitric oxide synthase-mediated alteration of mitochondrial OPA1 expression in ocular hypertensive rats. Invest Ophthalmol Vis Sci (2011) 0.87
Neuroprotection in Glaucoma. J Ophthalmic Vis Res (2016) 0.86
The progress in optic nerve regeneration, where are we? Neural Regen Res (2016) 0.86
Glial cell interactions and glaucoma. Curr Opin Ophthalmol (2015) 0.85
Neuroprotective therapies for glaucoma. Drug Des Devel Ther (2015) 0.85
Retinal Macroglial Responses in Health and Disease. Biomed Res Int (2016) 0.85
Adeno-associated virus-mediated expression of growth-associated protein-43 aggravates retinal ganglion cell death in experimental chronic glaucomatous injury. Mol Vis (2013) 0.85
CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa. Mol Ther (2015) 0.85
BDNF treatment and extended recovery from optic nerve trauma in the cat. Invest Ophthalmol Vis Sci (2013) 0.84
Quantifying optic nerve axons in a cat glaucoma model by a semi-automated targeted counting method. Mol Vis (2014) 0.82
Modeling glaucoma in rats by sclerosing aqueous outflow pathways to elevate intraocular pressure. Exp Eye Res (2015) 0.81
Stem cell therapy for glaucoma: possibilities and practicalities. Expert Rev Ophthalmol (2011) 0.81
The role of glial cells and the complement system in retinal diseases and Alzheimer's disease: common neural degeneration mechanisms. Exp Brain Res (2014) 0.81
The Potential of Human Stem Cells for the Study and Treatment of Glaucoma. Invest Ophthalmol Vis Sci (2016) 0.81
Mesenchymal stem cells for retinal diseases. Int J Ophthalmol (2011) 0.80
Microarray analysis of iris gene expression in mice with mutations influencing pigmentation. Invest Ophthalmol Vis Sci (2011) 0.80
Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma. J Neurosci (2012) 0.80
Gene therapy and the regeneration of retinal ganglion cell axons. Neural Regen Res (2014) 0.79
Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration. Int J Mol Sci (2016) 0.78
Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells: Applications for the Study and Treatment of Optic Neuropathies. Curr Ophthalmol Rep (2015) 0.78
Cytidine 5'-Diphosphocholine (Citicoline) in Glaucoma: Rationale of Its Use, Current Evidence and Future Perspectives. Int J Mol Sci (2015) 0.77
Expression of neuroglobin in ocular hypertension induced acute hypoxic-ischemic retinal injury in rats. Int J Ophthalmol (2011) 0.77
Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension. Invest Ophthalmol Vis Sci (2016) 0.77
A Period of Controlled Elevation of IOP (CEI) Produces the Specific Gene Expression Responses and Focal Injury Pattern of Experimental Rat Glaucoma. Invest Ophthalmol Vis Sci (2016) 0.76
Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells. Biomed Res Int (2016) 0.76
Advances in Gene Therapy for Diseases of the Eye. Hum Gene Ther (2016) 0.75
Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma. J Immunol (2016) 0.75
Overexpression of Brain-Derived Neurotrophic Factor Protects Large Retinal Ganglion Cells After Optic Nerve Crush in Mice. eNeuro (2017) 0.75
CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci (2016) 0.75
Interleukin-6: A Constitutive Modulator of Glycoprotein 130, Neuroinflammatory and Cell Survival Signaling in Retina. J Clin Cell Immunol (2016) 0.75
Protecting retinal ganglion cells. Eye (Lond) (2017) 0.75
Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro. Front Mol Neurosci (2017) 0.75
Glaucoma: Biological Trabecular and Neuroretinal Pathology with Perspectives of Therapy Innovation and Preventive Diagnosis. Front Neurosci (2017) 0.75
The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol (2006) 25.47
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Ther (1999) 7.96
Gene therapy restores vision in a canine model of childhood blindness. Nat Genet (2001) 7.88
Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol (1981) 5.09
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci (1995) 3.78
Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. Invest Ophthalmol Vis Sci (1998) 3.61
Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron (1995) 3.51
Neuronal death in glaucoma. Prog Retin Eye Res (1999) 3.46
Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve. Invest Ophthalmol (1974) 2.91
Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci (1994) 2.51
Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci (1998) 2.32
Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats. Invest Ophthalmol Vis Sci (2002) 2.24
Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp Eye Res (1995) 2.21
Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron (1998) 2.18
Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation. Brain (2007) 2.15
TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol (1997) 2.11
Potentiated necrosis of cultured cortical neurons by neurotrophins. Science (1995) 1.97
Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. Invest Ophthalmol Vis Sci (2001) 1.93
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells. Brain (2007) 1.87
Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci (2003) 1.83
Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS. Trends Neurosci (2000) 1.79
CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway. Eur J Neurosci (2004) 1.77
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms. Invest Ophthalmol Vis Sci (2007) 1.74
Immunocytochemical localization of TrkB in the central nervous system of the adult rat. J Comp Neurol (1997) 1.69
Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons. Science (1979) 1.66
Production and purification of recombinant adeno-associated virus. Methods Enzymol (2000) 1.66
Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucoma. Proc Natl Acad Sci U S A (2001) 1.61
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells. Proc Natl Acad Sci U S A (1998) 1.60
Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain. Gene Ther (2000) 1.59
Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation. Exp Eye Res (2002) 1.56
Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma. Proc Natl Acad Sci U S A (1999) 1.54
TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo. J Neurosci (2002) 1.51
Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain. Exp Neurol (2002) 1.49
Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional data. Invest Ophthalmol Vis Sci (2008) 1.47
Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa. Mol Ther (2001) 1.43
AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells. Gene Ther (2006) 1.41
Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol (1996) 1.36
Radioautographic and cytochemical ultrastructural studies of axoplasmic transport in the monkey optic nerve head. Invest Ophthalmol Vis Sci (1978) 1.33
The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines. J Neurobiol (1994) 1.33
Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model. Mol Ther (2002) 1.26
Ganglion cell death in glaucoma: pathology recapitulates ontogeny. Aust N Z J Ophthalmol (1995) 1.26
Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Invest Ophthalmol Vis Sci (1994) 1.25
Patterns of retinal ganglion cell survival after brain-derived neurotrophic factor administration in hypertensive eyes of rats. Neurosci Lett (2001) 1.21
A rat model of glaucoma induced by episcleral vein ligation. Exp Eye Res (2006) 1.19
Apoptosis in adult retinal ganglion cells after axotomy. J Neurobiol (1994) 1.15
Development of normal and injury-induced gene expression of aFGF, bFGF, CNTF, BDNF, GFAP and IGF-I in the rat retina. Exp Eye Res (2001) 1.15
BMP4 and CNTF are neuroprotective and suppress damage-induced proliferation of Müller glia in the retina. Mol Cell Neurosci (2004) 1.15
Application of encapsulated cell technology for retinal degenerative diseases. Expert Opin Biol Ther (2006) 1.14
BDNF enhances retinal ganglion cell survival in cats with optic nerve damage. Invest Ophthalmol Vis Sci (2001) 1.12
Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signaling. J Neurosci (2000) 1.11
Expression of ciliary neurotrophic factor activated by retinal Müller cells in eyes with NMDA- and kainic acid-induced neuronal death. Invest Ophthalmol Vis Sci (2000) 1.09
The combined effect of brain-derived neurotrophic factor and a free radical scavenger in experimental glaucoma. Invest Ophthalmol Vis Sci (2000) 1.09
Intraocular CNTF reduces vision in normal rats in a dose-dependent manner. Invest Ophthalmol Vis Sci (2007) 1.07
Apoptosis in retinal ganglion cell decrease in human glaucomatous eyes. Jpn J Ophthalmol (1997) 1.06
CNTF, not other trophic factors, promotes axonal regeneration of axotomized retinal ganglion cells in adult hamsters. Invest Ophthalmol Vis Sci (1999) 1.03
Effects of the neurotrophin brain-derived neurotrophic factor in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci (1999) 1.03
Time course of neurotrophic factor upregulation and retinal protection against light-induced damage after optic nerve section. Invest Ophthalmol Vis Sci (2005) 1.03
Bone morphogenetic proteins promote neurite outgrowth in retinal ganglion cells. Mol Vis (2005) 1.01
Induction of heat shock protein 72 protects retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci (2001) 1.00
BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons. Eur J Neurosci (1996) 1.00
Delivery of ciliary neurotrophic factor via lentiviral-mediated transfer protects axotomized retinal ganglion cells for an extended period of time. Hum Gene Ther (2003) 0.99
Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer. Brain Res (1999) 0.98
Retinal ganglion cells lose trophic responsiveness after axotomy. Neuron (1999) 0.98
A combination of CNTF and BDNF rescues rd photoreceptors but changes rod differentiation in the presence of RPE in retinal explants. Invest Ophthalmol Vis Sci (2001) 0.97
Rescue of axotomized retinal ganglion cells by BDNF gene electroporation in adult rats. Invest Ophthalmol Vis Sci (2002) 0.95
Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. Surv Ophthalmol (2001) 0.95
Ciliary neurotrophic factor protects retinal ganglion cells from axotomy-induced apoptosis via modulation of retinal glia in vivo. J Neurobiol (2005) 0.93
A prodrug of a selective inhibitor of inducible nitric oxide synthase is neuroprotective in the rat model of glaucoma. J Glaucoma (2002) 0.93
CNTF and BDNF have similar effects on retinal ganglion cell survival but differential effects on nitric oxide synthase expression soon after optic nerve injury. Invest Ophthalmol Vis Sci (2005) 0.93
Cloning, mapping, and retinal expression of the canine ciliary neurotrophic factor receptor alpha (CNTFRalpha). Invest Ophthalmol Vis Sci (2003) 0.93
Survival and axonal regeneration of retinal ganglion cells in adult cats. Prog Retin Eye Res (2002) 0.93
Experimental glaucoma and optic nerve transection induce simultaneous upregulation of proapoptotic and prosurvival genes. Invest Ophthalmol Vis Sci (2006) 0.92
Contributions of the optic tectum and the retina as sources of brain-derived neurotrophic factor for retinal ganglion cells in the chick embryo. J Neurosci (1998) 0.89
Localization of p75 neurotrophin receptor in the retina of the adult SD rat: an immunocytochemical study at light and electron microscopic levels. Glia (1998) 0.89
BDNF diminishes caspase-2 but not c-Jun immunoreactivity of neurons in retinal ganglion cell layer after transient ischemia. Invest Ophthalmol Vis Sci (1999) 0.88
Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats. Brain Pathol (2004) 0.87
Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons. Mol Cell Neurosci (1992) 0.85
Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain. Neuroscience (1999) 0.85
Neurite outgrowth in retinal ganglion cell culture. Methods Mol Biol (2007) 0.85
Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina. Invest Ophthalmol Vis Sci (2002) 0.84
Apoptotic cell death induced by optic nerve lesion in the neonatal rat. J Neurosci (1994) 0.83
Ciliary neurotrophic factor and its receptors are differentially expressed in the optic nerve transected adult rat retina. Brain Res (2004) 0.83
Neurotrophic factors minimize the retinal toxicity of verteporfin photodynamic therapy. Invest Ophthalmol Vis Sci (2007) 0.83
Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo. J Neurosci (1998) 0.83
Anti-apoptotic effects of CNTF gene transfer on photoreceptor degeneration in experimental antibody-induced retinopathy. J Autoimmun (2003) 0.81
Optic nerve regeneration within artificial Schwann cell graft in the adult rat. Brain Res Bull (2001) 0.80
Co-expression of mRNA for neurotrophic factors in human neurons and glial cells in culture. J Neuropathol Exp Neurol (1994) 0.78
Expression of ciliary neurotrophic factor (CNTF) and its tripartite receptor complex by cells of the human optic nerve head. Mol Vis (2007) 0.78
Brain-derived neurotrophic factor modulates GAP-43 but not T alpha1 expression in injured retinal ganglion cells of adult rats. J Neurosci Res (1997) 0.77
The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol (2002) 8.35
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics. Proc Natl Acad Sci U S A (2008) 7.16
A muscleblind knockout model for myotonic dystrophy. Science (2003) 5.93
Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods (2002) 5.30
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness. Mol Ther (2005) 4.74
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. N Engl J Med (2008) 4.46
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Determinants of normal retinal nerve fiber layer thickness measured by Stratus OCT. Ophthalmology (2007) 3.88
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years. Arch Ophthalmol (2011) 3.79
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nat Genet (2011) 3.55
TiGER: a database for tissue-specific gene expression and regulation. BMC Bioinformatics (2008) 3.37
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc Natl Acad Sci U S A (2010) 3.33
Improvement and decline in vision with gene therapy in childhood blindness. N Engl J Med (2015) 3.16
Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year. Hum Gene Ther (2009) 3.07
High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors. Mol Ther (2008) 2.93
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell (2012) 2.81
Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement. Proc Natl Acad Sci U S A (2013) 2.71
Vision 1 year after gene therapy for Leber's congenital amaurosis. N Engl J Med (2009) 2.57
Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA). Mol Vis (2005) 2.55
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
Choroidal thickness change after water drinking is greater in angle closure than in open angle eyes. Invest Ophthalmol Vis Sci (2012) 2.48
Restoration of cone vision in a mouse model of achromatopsia. Nat Med (2007) 2.44
Gene therapy for red-green colour blindness in adult primates. Nature (2009) 2.44
Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78. Proc Natl Acad Sci U S A (2010) 2.40
Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol (2005) 2.31
Doctor-patient communication, health-related beliefs, and adherence in glaucoma results from the Glaucoma Adherence and Persistency Study. Ophthalmology (2008) 2.29
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis. Mol Ther (2005) 2.27
Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues. Nucleic Acids Res (2006) 2.26
Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats. Invest Ophthalmol Vis Sci (2002) 2.24
Gene therapy rescues cone function in congenital achromatopsia. Hum Mol Genet (2010) 2.18
Central corneal thickness and corneal hysteresis associated with glaucoma damage. Am J Ophthalmol (2006) 2.14
Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection. Mol Ther (2006) 2.13
Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy. Ann Neurol (2002) 2.13
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa. Proc Natl Acad Sci U S A (2012) 2.12
Adherence with topical glaucoma medication monitored electronically the Travatan Dosing Aid study. Ophthalmology (2008) 2.10
Development and validation of an improved neurological hemifield test to identify chiasmal and postchiasmal lesions by automated perimetry. Invest Ophthalmol Vis Sci (2014) 2.05
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci (2002) 2.03
Risk factors and open-angle glaucoma: classification and application. J Glaucoma (2007) 1.99
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet (2011) 1.98
Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model. Proc Natl Acad Sci U S A (2012) 1.94
The impact of visual impairment and eye disease on vision-related quality of life in a Mexican-American population: proyecto VER. Invest Ophthalmol Vis Sci (2002) 1.92
Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness. Mol Ther (2011) 1.91
Biomechanics of the human posterior sclera: age- and glaucoma-related changes measured using inflation testing. Invest Ophthalmol Vis Sci (2012) 1.89
Using pharmacy claims data to study adherence to glaucoma medications: methodology and findings of the Glaucoma Adherence and Persistency Study (GAPS). Invest Ophthalmol Vis Sci (2007) 1.87
Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci (2003) 1.83
Visual field defects and retinal ganglion cell losses in patients with glaucoma. Arch Ophthalmol (2006) 1.83
Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis. PLoS Med (2005) 1.83
Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. PLoS Genet (2010) 1.83
Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension. Invest Ophthalmol Vis Sci (2002) 1.82
Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis. Hum Gene Ther (2006) 1.81
Prolonged recovery of retinal structure/function after gene therapy in an Rs1h-deficient mouse model of x-linked juvenile retinoschisis. Mol Ther (2005) 1.79
Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation. PLoS Med (2007) 1.79
Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina. Mol Ther (2010) 1.77
SOD2 knockdown mouse model of early AMD. Invest Ophthalmol Vis Sci (2007) 1.77
Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol (2003) 1.75
Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa. Mol Ther (2010) 1.75
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms. Invest Ophthalmol Vis Sci (2007) 1.74
Choroidal thickness measured by spectral domain optical coherence tomography: factors affecting thickness in glaucoma patients. Ophthalmology (2011) 1.74
Risk factors for poor adherence to eyedrops in electronically monitored patients with glaucoma. Ophthalmology (2009) 1.74
Optic disc morphology in open-angle glaucoma compared with anterior ischemic optic neuropathies. Invest Ophthalmol Vis Sci (2009) 1.71
A comprehensive review of retinal gene therapy. Mol Ther (2013) 1.70
SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I. Ann Neurol (2004) 1.70
AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation. Invest Ophthalmol Vis Sci (2008) 1.68
Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosis. PLoS Med (2006) 1.67
Genome-wide prediction and characterization of interactions between transcription factors in Saccharomyces cerevisiae. Nucleic Acids Res (2006) 1.65
Construction of human activity-based phosphorylation networks. Mol Syst Biol (2013) 1.59
Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. Am J Pathol (2002) 1.59
Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential. Mol Vis (2008) 1.59
AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci (2002) 1.58
Adherence and persistence with glaucoma therapy. Surv Ophthalmol (2008) 1.57
Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae. Invest Ophthalmol Vis Sci (2012) 1.56
Influence of corneal structure, corneal responsiveness, and other ocular parameters on tonometric measurement of intraocular pressure. J Glaucoma (2007) 1.52
Aqueous flow through the iris-lens channel: estimates of differential pressure between the anterior and posterior chambers. J Glaucoma (2004) 1.52
Outcomes and bleb-related complications of trabeculectomy. Ophthalmology (2012) 1.52
Differential susceptibility to experimental glaucoma among 3 mouse strains using bead and viscoelastic injection. Exp Eye Res (2010) 1.51
TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo. J Neurosci (2002) 1.51
Oncomodulin links inflammation to optic nerve regeneration. Proc Natl Acad Sci U S A (2009) 1.50
Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional data. Invest Ophthalmol Vis Sci (2008) 1.47
Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma. Proc Natl Acad Sci U S A (2011) 1.47
A model to study differences between primary and secondary degeneration of retinal ganglion cells in rats by partial optic nerve transection. Invest Ophthalmol Vis Sci (2003) 1.46
A splice-site mutation in a retina-specific exon of BBS8 causes nonsyndromic retinitis pigmentosa. Am J Hum Genet (2010) 1.46
Interventions improve poor adherence with once daily glaucoma medications in electronically monitored patients. Ophthalmology (2009) 1.46
Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage. J Neurosci (2003) 1.44
Adeno-associated virus-vectored gene therapy for retinal disease. Hum Gene Ther (2005) 1.43
High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization. Gene Expr Patterns (2005) 1.43
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression. Mol Ther (2009) 1.42
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol (2005) 1.41
Inducible expression of cre recombinase in the retinal pigmented epithelium. Invest Ophthalmol Vis Sci (2008) 1.41
Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation. J Biol Chem (2004) 1.41
The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina. Invest Ophthalmol Vis Sci (2005) 1.40