| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity.
|
Genes Dev
|
2003
|
2.97
|
|
2
|
Structural insight into partner specificity and phosphoryl transfer in two-component signal transduction.
|
Cell
|
2009
|
2.94
|
|
3
|
Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome.
|
Blood
|
2010
|
2.77
|
|
4
|
Suggested guidelines for the diagnosis and management of urea cycle disorders.
|
Orphanet J Rare Dis
|
2012
|
2.46
|
|
5
|
COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability.
|
Mol Cell
|
2008
|
2.34
|
|
6
|
A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis.
|
PLoS Genet
|
2010
|
2.05
|
|
7
|
Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes.
|
Genes Dev
|
2004
|
1.72
|
|
8
|
PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 is a plant-specific SEC12-related protein that enables the endoplasmic reticulum exit of a high-affinity phosphate transporter in Arabidopsis.
|
Plant Cell
|
2005
|
1.71
|
|
9
|
The mechanism of signal transduction by two-component systems.
|
Curr Opin Struct Biol
|
2010
|
1.61
|
|
10
|
N-terminal domain-mediated homodimerization is required for photoreceptor activity of Arabidopsis CRYPTOCHROME 1.
|
Plant Cell
|
2005
|
1.60
|
|
11
|
Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation.
|
Plant Cell
|
2004
|
1.60
|
|
12
|
Gibberellins modulate light signaling pathways to prevent Arabidopsis seedling de-etiolation in darkness.
|
Plant J
|
2007
|
1.58
|
|
13
|
Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis.
|
Structure
|
2002
|
1.57
|
|
14
|
Mutations at CRE1 impair cytokinin-induced repression of phosphate starvation responses in Arabidopsis.
|
Plant J
|
2002
|
1.45
|
|
15
|
LZF1/SALT TOLERANCE HOMOLOG3, an Arabidopsis B-box protein involved in light-dependent development and gene expression, undergoes COP1-mediated ubiquitination.
|
Plant Cell
|
2008
|
1.45
|
|
16
|
Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis.
|
Haematologica
|
2009
|
1.44
|
|
17
|
Gene structure, organization, expression, and potential regulatory mechanisms of arginine catabolism in Enterococcus faecalis.
|
J Bacteriol
|
2002
|
1.30
|
|
18
|
Arabidopsis COP1/SPA1 complex and FHY1/FHY3 associate with distinct phosphorylated forms of phytochrome A in balancing light signaling.
|
Mol Cell
|
2008
|
1.29
|
|
19
|
Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosa.
|
J Mol Biol
|
2005
|
1.27
|
|
20
|
The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginine.
|
Proc Natl Acad Sci U S A
|
2007
|
1.23
|
|
21
|
Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis.
|
Plant Cell
|
2014
|
1.23
|
|
22
|
Light and the E3 ubiquitin ligase COP1/SPA control the protein stability of the MYB transcription factors PAP1 and PAP2 involved in anthocyanin accumulation in Arabidopsis.
|
Plant J
|
2013
|
1.22
|
|
23
|
Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens.
|
Blood
|
2010
|
1.20
|
|
24
|
The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis.
|
J Mol Biol
|
2005
|
1.17
|
|
25
|
Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PII.
|
Proc Natl Acad Sci U S A
|
2010
|
1.15
|
|
26
|
A novel two-domain architecture within the amino acid kinase enzyme family revealed by the crystal structure of Escherichia coli glutamate 5-kinase.
|
J Mol Biol
|
2007
|
1.09
|
|
27
|
Arginine biosynthesis in Thermotoga maritima: characterization of the arginine-sensitive N-acetyl-L-glutamate kinase.
|
J Bacteriol
|
2004
|
1.05
|
|
28
|
The course of phosphorus in the reaction of N-acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF(4)(-) transition state mimic.
|
J Mol Biol
|
2003
|
1.04
|
|
29
|
Molecular defects in human carbamoy phosphate synthetase I: mutational spectrum, diagnostic and protein structure considerations.
|
Hum Mutat
|
2011
|
1.04
|
|
30
|
The gene cluster for agmatine catabolism of Enterococcus faecalis: study of recombinant putrescine transcarbamylase and agmatine deiminase and a snapshot of agmatine deiminase catalyzing its reaction.
|
J Bacteriol
|
2006
|
1.02
|
|
31
|
Structural and functional insights into endoglin ligand recognition and binding.
|
PLoS One
|
2012
|
1.02
|
|
32
|
Site-directed mutagenesis of Escherichia coli acetylglutamate kinase and aspartokinase III probes the catalytic and substrate-binding mechanisms of these amino acid kinase family enzymes and allows three-dimensional modelling of aspartokinase.
|
J Mol Biol
|
2003
|
0.98
|
|
33
|
Arginine and nitrogen storage.
|
Curr Opin Struct Biol
|
2008
|
0.94
|
|
34
|
Interallelic complementation at the Arabidopsis CRE1 locus uncovers independent pathways for the proliferation of vascular initials and canonical cytokinin signalling.
|
Plant J
|
2004
|
0.93
|
|
35
|
Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine.
|
J Inherit Metab Dis
|
2011
|
0.93
|
|
36
|
Site-directed mutagenesis studies of acetylglutamate synthase delineate the site for the arginine inhibitor.
|
FEBS Lett
|
2008
|
0.90
|
|
37
|
Improved cross-linked enzyme aggregates for the production of desacetyl beta-lactam antibiotics intermediates.
|
Bioresour Technol
|
2009
|
0.90
|
|
38
|
Structural insight on the control of urea synthesis: identification of the binding site for N-acetyl-L-glutamate, the essential allosteric activator of mitochondrial carbamoyl phosphate synthetase.
|
Biochem J
|
2009
|
0.87
|
|
39
|
Dissection of Escherichia coli glutamate 5-kinase: functional impact of the deletion of the PUA domain.
|
FEBS Lett
|
2005
|
0.87
|
|
40
|
Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinase.
|
PLoS One
|
2012
|
0.87
|
|
41
|
Understanding carbamoyl-phosphate synthetase I (CPS1) deficiency by using expression studies and structure-based analysis.
|
Hum Mutat
|
2010
|
0.87
|
|
42
|
Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteria.
|
J Mol Biol
|
2010
|
0.86
|
|
43
|
Purification of the COP9 signalosome from porcine spleen, human cell lines, and Arabidopsis thaliana plants.
|
Methods Enzymol
|
2005
|
0.85
|
|
44
|
Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites.
|
FEBS Lett
|
2006
|
0.85
|
|
45
|
Mechanism of arginine regulation of acetylglutamate synthase, the first enzyme of arginine synthesis.
|
FEBS Lett
|
2008
|
0.85
|
|
46
|
Towards structural understanding of feedback control of arginine biosynthesis: cloning and expression of the gene for the arginine-inhibited N-acetyl-L-glutamate kinase from Pseudomonas aeruginosa, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.
|
Acta Crystallogr D Biol Crystallogr
|
2002
|
0.84
|
|
47
|
Understanding carbamoyl phosphate synthetase deficiency: impact of clinical mutations on enzyme functionality.
|
J Mol Biol
|
2005
|
0.83
|
|
48
|
Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.
|
J Mol Biol
|
2010
|
0.82
|
|
49
|
Basis of arginine sensitivity of microbial N-acetyl-L-glutamate kinases: mutagenesis and protein engineering study with the Pseudomonas aeruginosa and Escherichia coli enzymes.
|
J Bacteriol
|
2008
|
0.82
|
|
50
|
Molecular physiology of phosphoryl group transfer from carbamoyl phosphate by a hyperthermophilic enzyme at low temperature.
|
Biochemistry
|
2002
|
0.81
|
|
51
|
Molecular characterization of carbamoyl-phosphate synthetase (CPS1) deficiency using human recombinant CPS1 as a key tool.
|
Hum Mutat
|
2013
|
0.80
|
|
52
|
Citrin deficiency in a Romanian child living in Spain highlights the worldwide distribution of this defect and illustrates the value of nutritional therapy.
|
Mol Genet Metab
|
2013
|
0.80
|
|
53
|
Roles of ubiquitination in the control of phosphate starvation responses in plants(f).
|
J Integr Plant Biol
|
2013
|
0.80
|
|
54
|
Identification of seven novel missense mutations, two splice-site mutations, two microdeletions and a polymorphic amino acid substitution in the gene for ornithine transcarbamylase (OTC) in patients with OTC deficiency.
|
Hum Mutat
|
2002
|
0.79
|
|
55
|
Mutant alleles associated with late-onset ornithine transcarbamylase deficiency in male patients have recurrently arisen and have been retained in some populations.
|
J Hum Genet
|
2009
|
0.77
|
|
56
|
The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations.
|
FEBS J
|
2014
|
0.77
|
|
57
|
New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.
|
PLoS One
|
2012
|
0.77
|
|
58
|
Glutamate-5-kinase from Escherichia coli: gene cloning, overexpression, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.
|
Acta Crystallogr D Biol Crystallogr
|
2004
|
0.77
|
|
59
|
Functional dissection of N-acetylglutamate synthase (ArgA) of Pseudomonas aeruginosa and restoration of its ancestral N-acetylglutamate kinase activity.
|
J Bacteriol
|
2012
|
0.77
|
|
60
|
A crystallographic glimpse of a nucleotide triphosphate (AMPPNP) bound to a protein surface: external and internal AMPPNP molecules in crystalline N-acetyl-L-glutamate kinase.
|
Acta Crystallogr D Biol Crystallogr
|
2002
|
0.76
|
|
61
|
Proteomics identifies ubiquitin-proteasome targets and new roles for chromatin-remodeling in the Arabidopsis response to phosphate starvation.
|
J Proteomics
|
2013
|
0.76
|
|
62
|
The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation.
|
Biochem J
|
2011
|
0.76
|
|
63
|
Mechanism of oligomerization of Escherichia coli carbamoyl phosphate synthetase and modulation by the allosteric effectors. A site-directed mutagenesis study.
|
FEBS Lett
|
2002
|
0.76
|
|
64
|
H intragenic polymorphisms and haplotype analysis in the ornithine transcarbamylase (OTC) gene and their relevance for tracking the inheritance of OTC deficiency.
|
Hum Mutat
|
2002
|
0.75
|
|
65
|
The site for the allosteric activator GTP of Escherichia coli UMP kinase.
|
FEBS Lett
|
2008
|
0.75
|
|
66
|
First-time crystallization and preliminary X-ray crystallographic analysis of a bacterial-archaeal type UMP kinase, a key enzyme in microbial pyrimidine biosynthesis.
|
Biochim Biophys Acta
|
2004
|
0.75
|
|
67
|
Mechanism of allosteric modulation of Escherichia coli carbamoyl phosphate synthetase probed by site-directed mutagenesis of ornithine site residues.
|
FEBS Lett
|
2002
|
0.75
|