The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation.

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Published in Biochem J on June 01, 2011

Authors

Silvia Montoro-García1, Fernando Gil-Ortiz, Francisco García-Carmona, Luis Mariano Polo, Vicente Rubio, Álvaro Sánchez-Ferrer

Author Affiliations

1: Department of Biochemistry and Molecular Biology-A, Faculty of Biology, University of Murcia, Campus Espinardo, E-30100 Murcia, Spain.

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