Published in Br J Cancer on December 09, 2008
Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol (2010) 6.04
Monoclonal antibodies for the treatment of cancer. Semin Cancer Biol (2012) 1.26
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J Clin Invest (2014) 1.21
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma. MAbs (2015) 1.16
Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function. Blood (2012) 1.03
Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy. Biomaterials (2011) 1.02
T-cell-independent antitumor effects of CD40 ligation. Int Rev Immunol (2012) 0.99
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ. J Exp Clin Cancer Res (2014) 0.89
The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge. MAbs (2011) 0.88
Engineered protease-resistant antibodies with selectable cell-killing functions. J Biol Chem (2013) 0.86
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions. MAbs (2015) 0.85
Enhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpG. Cancer Immunol Immunother (2012) 0.84
Toll-like Receptor 4 Ligands Down-regulate Fcγ Receptor IIb (FcγRIIb) via MARCH3 Protein-mediated Ubiquitination. J Biol Chem (2015) 0.77
Fcγ receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies. J Biol Chem (2013) 0.77
Cancer immunotherapy: activating innate and adaptive immunity through CD40 agonists. Expert Rev Anticancer Ther (2016) 0.75
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood (2002) 8.76
Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol (2003) 6.77
CD40-CD40 ligand. J Leukoc Biol (2000) 6.28
Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood (1997) 3.19
Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions. Somat Cell Mol Genet (1986) 2.03
Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications. Cancer Res (2005) 1.84
Fc gamma RIIIa and Fc gamma RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia. Blood (2003) 1.61
Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells. Mol Cancer Ther (2008) 1.61
Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities. Eur J Immunol (1999) 1.56
Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces cytotoxicity in human multiple myeloma cells: clinical implications. Cancer Res (2004) 1.42
Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40. Cancer Res (2005) 1.28
Fcgamma receptor-dependent effector mechanisms regulate CD19 and CD20 antibody immunotherapies for B lymphocyte malignancies and autoimmunity. Springer Semin Immunopathol (2006) 1.24
The therapeutic use of rituximab in non-Hodgkin's lymphoma. Eur J Haematol Suppl (2007) 1.23
Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities. Blood (2006) 1.21
High-level expression of proteins in mammalian cells using transcription regulatory sequences from the Chinese hamster EF-1alpha gene. Biotechnol Prog (2004) 1.16
Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30. Blood (2007) 1.09
CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line. J Immunol (1994) 0.96
CD40 expression in Hodgkin's disease. Am J Pathol (1994) 0.94
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med (1996) 23.76
Evaluation of the E test, a novel method of quantifying antimicrobial activity. J Antimicrob Chemother (1991) 4.06
A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children. N Engl J Med (1992) 4.05
Insertion mutations in the dam gene of Escherichia coli K-12. Mol Gen Genet (1983) 3.61
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
A deletion map of the human Y chromosome based on DNA hybridization. Am J Hum Genet (1986) 3.03
Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun (1997) 2.97
Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol (2001) 2.85
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity. Nat Immunol (2000) 2.78
Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol (1999) 2.78
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol (2001) 2.75
Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci U S A (1999) 2.63
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem (2000) 2.57
Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature (2000) 2.51
Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes. Antiviral Res (2006) 2.43
Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med (1990) 2.42
Neutrophil apoptosis in the acute respiratory distress syndrome. Am J Respir Crit Care Med (1997) 2.26
Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol (1999) 2.25
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. J Exp Med (1996) 2.21
Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation. Am J Pathol (2001) 2.18
The importance of leukotrienes in airway inflammation in a mouse model of asthma. J Exp Med (1996) 2.11
Perfusion of the spleen with blood containing prostaglandin E1: transmitter liberation and uptake. Proc R Soc Lond B Biol Sci (1969) 2.11
Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo. J Immunol (1999) 2.11
Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover. J Immunol (1998) 2.01
Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages. J Leukoc Biol (2007) 1.99
A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J (1994) 1.98
Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice. J Immunol (2001) 1.95
TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice. Nat Immunol (2001) 1.92
Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study. Cell Tissue Res (1984) 1.91
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol (1998) 1.91
Requirement for CD154 in the progression of atherosclerosis. Nat Med (1999) 1.86
Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia. Infect Immun (1996) 1.82
West Nile virus neuroinvasion and encephalitis induced by macrophage depletion in mice. Arch Virol (1996) 1.79
Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim Biophys Acta (1994) 1.79
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proc Natl Acad Sci U S A (2009) 1.79
Apoptosis and the cell cycle. Curr Opin Cell Biol (1995) 1.76
Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res (1998) 1.76
CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers. Br J Cancer (2008) 1.75
CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. J Virol (1996) 1.74
Translocation of the 85-kDa phospholipase A2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen. J Biol Chem (1995) 1.65
Safety guidelines for use of nitric oxide. Lancet (1992) 1.62
Inhibition of Cuticular Lipid Biosynthesis in Pisum sativum by Thiocarbamates. Plant Physiol (1974) 1.61
Long-term attendance at a family practice teaching unit. Qualitative study of patients' views. Can Fam Physician (1997) 1.60
The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Exp Med (1999) 1.58
Transcytosis of gastrointestinal epithelial cells by Escherichia coli K1. Pediatr Res (2001) 1.57
Lithium dilution cardiac output measurement: a comparison with thermodilution. Crit Care Med (1997) 1.57
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J Virol (1997) 1.56
Activity and spectrum of 22 antimicrobial agents tested against urinary tract infection pathogens in hospitalized patients in Latin America: report from the second year of the SENTRY antimicrobial surveillance program (1998). J Antimicrob Chemother (2000) 1.56
Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues. J Virol (1996) 1.56
Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection. J Pharmacol Exp Ther (2001) 1.55
TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. Proc Natl Acad Sci U S A (1991) 1.53
Increase in laminin expression in allergic airway remodelling and decrease by dexamethasone. Eur Respir J (2004) 1.52
Role of macrophages during Theiler's virus infection. J Virol (1997) 1.52
Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice. J Immunol (1996) 1.51
Human malaria in immunocompromised mice: an in vivo model to study defense mechanisms against Plasmodium falciparum. J Exp Med (2000) 1.50
Behavioral changes correlated with brain-stem auditory evoked responses in term infants with moderate hyperbilirubinemia. J Pediatr (1990) 1.50
Helicobacter pylori eradication does not exacerbate reflux symptoms in gastroesophageal reflux disease. Gastroenterology (2001) 1.50
Impaired primary T cell responses in L-selectin-deficient mice. J Exp Med (1996) 1.46
Protein conformational changes in the bacteriorhodopsin photocycle. J Mol Biol (1999) 1.45
Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol (2000) 1.42
Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis. J Virol (1999) 1.42
Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. Mol Cell Biol (1997) 1.41
Do not resuscitate discussions in a hospital-based home care program. J Am Geriatr Soc (1989) 1.40
Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar typhimurium infection despite attenuated cytokine response. Infect Immun (2001) 1.40
Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy. Liver (2000) 1.39
Percutaneous removal of infected permanent pacemaker leads using a simple coaxial dilating system. Pacing Clin Electrophysiol (1994) 1.39
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease. Neurology (2008) 1.39
A longitudinal study of psychological adjustment to familial genetic risk assessment for ovarian cancer. Gynecol Oncol (1999) 1.38
Genomic organization of the structural proteins of borna disease virus revealed by a cDNA clone encoding the 38-kDa protein. Virology (1993) 1.37
Use of saliva in therapeutic drug monitoring. Clin Chem (1977) 1.37
Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J Clin Invest (1997) 1.36
"It's not what you know, but who you knew": examining the relationship between behavior change and AIDS mortality in Africa. AIDS Educ Prev (2001) 1.36
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. Arthritis Rheum (2004) 1.32
Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. Arthritis Rheum (2000) 1.32
Health effects of depleted uranium on exposed Gulf War veterans. Environ Res (2000) 1.32
Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection. J Virol (1997) 1.32
Repopulation of macrophages in popliteal lymph nodes of mice after liposome-mediated depletion. J Leukoc Biol (1990) 1.31
Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. Br J Pharmacol (2001) 1.30
Longitudinal transition plans in programs for severely handicapped students. Except Child (1981) 1.30
Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism. J Immunol (2001) 1.29
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo. J Immunol (1997) 1.29
CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses. J Immunol (1999) 1.28
Sleep-wake pattern in preterm infants under two different care schedules during four-day polygraphic recording. Neuropediatrics (1981) 1.27
Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein. Eur Respir J (2008) 1.27
Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. Circulation (1994) 1.26
Promoter substitution and deletion analysis of upstream region required for rpoS translational regulation. J Bacteriol (1998) 1.25
Enzymatically controlled drug delivery. Proc Natl Acad Sci U S A (1988) 1.25
Changes in cytokine mRNA levels in experimental corneal allografts after local clodronate-liposome treatment. Invest Ophthalmol Vis Sci (1999) 1.22
Occurrence of single-point gyrA mutations among ciprofloxacin-susceptible Escherichia coli isolates causing urinary tract infections in Latin America. Diagn Microbiol Infect Dis (2000) 1.22
Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses. J Immunol (1996) 1.21
Liposomes in immunology: evidence that their adjuvant effect results from surface exposition of the antigens. Cell Immunol (1980) 1.20
Characterization of group B streptococcal invasion of human chorion and amnion epithelial cells In vitro. Infect Immun (1998) 1.19