Published in N Engl J Med on August 13, 1992
Hepatitis A: old and new. Clin Microbiol Rev (2001) 1.82
Six years' follow-up after hepatitis A vaccination. N Engl J Med (1998) 1.55
New developments in hepatitis A control. Can Fam Physician (1995) 1.42
Mutations within the 5' nontranslated RNA of cell culture-adapted hepatitis A virus which enhance cap-independent translation in cultured African green monkey kidney cells. J Virol (1996) 1.34
Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells. J Virol (1994) 1.28
The Cys-rich region of hepatitis A virus cellular receptor 1 is required for binding of hepatitis A virus and protective monoclonal antibody 190/4. J Virol (1998) 1.21
Hepatitis A virus infection: Is it an important hazard to public health?: hazards of HAV for public health. Hepat Mon (2011) 1.16
Overcoming T cell-mediated immunopathology to achieve safe RSV vaccination. Future Virol (2008) 1.01
Evolutionary origins of hepatitis A virus in small mammals. Proc Natl Acad Sci U S A (2015) 1.01
Protective effect of inactivated hepatitis A vaccine against the outbreak of hepatitis A in an open rural community. World J Gastroenterol (2008) 0.97
A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses. PLoS One (2012) 0.93
Safety and effectiveness of the new inactivated hepatitis A virus vaccine. CMAJ (1995) 0.92
Peek-a-boo: membrane hijacking and the pathogenesis of viral hepatitis. Trends Microbiol (2013) 0.92
Hepatitis A vaccination during an outbreak among gay men in Montréal, Canada, 1995-1997. J Epidemiol Community Health (2001) 0.92
Characterization of replication-competent hepatitis A virus constructs containing insertions at the N terminus of the polyprotein. J Virol (1998) 0.91
Report of the Workgroup on Viral Diseases. Bull World Health Organ (1998) 0.87
Declining hepatitis A seroprevalence in adults in Catalonia (Spain): a population-based study. BMC Infect Dis (2007) 0.86
The increasing prominence of household transmission of hepatitis A in an area undergoing a shift in endemicity. Epidemiol Infect (2005) 0.86
Seroepidemiology of hepatitis A virus in Kuwait. World J Gastroenterol (2009) 0.84
Vaccination against hepatitis A in children: A review of the evidence. Ther Clin Risk Manag (2007) 0.83
Cohort effects in dynamic models and their impact on vaccination programmes: an example from hepatitis A. BMC Infect Dis (2006) 0.83
Hepatitis A vaccination in developing countries: Is Syria next? Avicenna J Med (2012) 0.82
Inhibitor-Based Therapeutics for Treatment of Viral Hepatitis. J Clin Transl Hepatol (2016) 0.81
Hepatitis A vaccine. N Engl J Med (1992) 0.81
Evaluation of hepatitis A vaccine in post-exposure prophylaxis, The Netherlands, 2004-2012. PLoS One (2013) 0.80
Long-term protective effect of post-exposure Havrix administration during viral hepatitis Type A outbreaks. Eur J Epidemiol (2006) 0.80
Prophylactic and Therapeutic Vaccination against Hepatitis C Virus (HCV): Developments and Future Perspectives. Viruses (2009) 0.80
Live attenuated hepatitis A vaccines developed in China. Hum Vaccin Immunother (2013) 0.80
Active immunization in the United States: developments over the past decade. Clin Microbiol Rev (2001) 0.80
Formalin Inactivation of Japanese Encephalitis Virus Vaccine Alters the Antigenicity and Immunogenicity of a Neutralization Epitope in Envelope Protein Domain III. PLoS Negl Trop Dis (2015) 0.78
Viral hepatitis and the surgeon. HPB (Oxford) (2005) 0.77
Liver disease. Postgrad Med J (1994) 0.76
Hepatitis A vaccination. West J Med (1993) 0.76
Viral hepatitis. Arch Dis Child (1994) 0.75
Impact of universal mass vaccination with monovalent inactivated hepatitis A vaccines - A systematic review. Hum Vaccin Immunother (2016) 0.75
Protecting contacts of hepatitis A: what's the difference between vaccine and human normal immunoglobulin? Epidemiol Infect (2008) 0.75
Hepatitis A infection during pregnancy. Can Fam Physician (2015) 0.75
Control of hepatitis A infection in the U.S. West J Med (1999) 0.75
Vaccine-preventable infections in Systemic Lupus Erythematosus. Hum Vaccin Immunother (2016) 0.75
Hepatitis A vaccines: How will we use them? Can J Infect Dis (1993) 0.75
Persistence of immunity from 1 year of age after one or two doses of hepatitis A vaccine given to children in Argentina. Hepat Med (2012) 0.75
Hepatitis A, hepatitis B, and combination hepatitis vaccines for immunoprophylaxis: an update. Dig Dis Sci (2002) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
Basic local alignment search tool. J Mol Biol (1990) 659.07
A greedy algorithm for aligning DNA sequences. J Comput Biol (2000) 47.89
Optimal alignments in linear space. Comput Appl Biosci (1988) 38.10
Protein sequence similarity searches using patterns as seeds. Nucleic Acids Res (1998) 23.87
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med (1996) 23.76
The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res (2007) 23.13
A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res (1998) 22.69
Aligning two sequences within a specified diagonal band. Comput Appl Biosci (1992) 19.31
Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis (1985) 19.03
PipMaker--a web server for aligning two genomic DNA sequences. Genome Res (2000) 17.46
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science (2000) 10.14
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis (1999) 9.81
The Mouse Genome Database (MGD): integrating biology with the genome. Nucleic Acids Res (2004) 8.91
Tau suppression in a neurodegenerative mouse model improves memory function. Science (2005) 8.66
Long human-mouse sequence alignments reveal novel regulatory elements: a reason to sequence the mouse genome. Genome Res (1997) 8.49
Scoring pairwise genomic sequence alignments. Pac Symp Biocomput (2002) 8.42
Laboratory investigation of a multistate food-borne outbreak of Escherichia coli O157:H7 by using pulsed-field gel electrophoresis and phage typing. J Clin Microbiol (1994) 8.37
The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology. Nucleic Acids Res (2005) 8.19
Comparison of DNA sequences with protein sequences. Genomics (1997) 7.76
Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell (1996) 6.87
Mapping sequenced E.coli genes by computer: software, strategies and examples. Nucleic Acids Res (1991) 6.29
Expression of a Delta homologue in prospective neurons in the chick. Nature (1995) 5.73
Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res (1997) 4.82
A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell (1994) 4.56
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science (2001) 4.25
Alignment of Escherichia coli K12 DNA sequences to a genomic restriction map. Nucleic Acids Res (1990) 4.07
Evaluation of the E test, a novel method of quantifying antimicrobial activity. J Antimicrob Chemother (1991) 4.06
A cap-binding protein complex mediating U snRNA export. Nature (1995) 3.89
Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res (1998) 3.80
Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights. Gene (1997) 3.77
The natural history of recurrent herpes simplex labialis: implications for antiviral therapy. N Engl J Med (1977) 3.61
Insertion mutations in the dam gene of Escherichia coli K-12. Mol Gen Genet (1983) 3.61
Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol (1989) 3.59
A local alignment tool for very long DNA sequences. Comput Appl Biosci (1995) 3.58
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood (1997) 3.56
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature (1995) 3.39
Attachment of local health authority staff to general practices. 1. A study in three county boroughs with special reference to health visiting. Nurs Times (1968) 3.21
Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens. N Engl J Med (1981) 3.17
Actin cables and epidermal movement in embryonic wound healing. Nature (1992) 3.11
A deletion map of the human Y chromosome based on DNA hybridization. Am J Hum Genet (1986) 3.03
Post-processing long pairwise alignments. Bioinformatics (1999) 3.00
A space-efficient algorithm for local similarities. Comput Appl Biosci (1990) 2.98
Modulation of the two promoters of the galactose operon of Escherichia coli. Nature (1979) 2.91
Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res (2001) 2.89
Notch signalling and the synchronization of the somite segmentation clock. Nature (2000) 2.84
Polycystic ovaries treated by laparoscopic laser vaporization. Fertil Steril (1989) 2.77
A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas (1996) 2.74
Analysis of the quality and utility of random shotgun sequencing at low redundancies. Genome Res (1998) 2.74
Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line. Nature (1980) 2.72
The Peckham Health Centre, "PEP", and the concept of general practice during the 1930s and 1940s. Med Hist (1983) 2.65
Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci U S A (1999) 2.63
Pediatric telephone triage protocols: standardized decisionmaking or a false sense of security? Ann Emerg Med (1999) 2.58
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem (2000) 2.57
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Metabolism of (14C) cefaclor, a cephalosporin antibiotic, in three species of laboratory animals. Antimicrob Agents Chemother (1976) 2.52
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Hum Mol Genet (2001) 2.46
Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation (2001) 2.46
Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes. Antiviral Res (2006) 2.43
Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood (1990) 2.38
Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics (1994) 2.36
Nonfatal childhood injuries: a survey at the Children's Hospital of eastern Ontario. CMAJ (1992) 2.32
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci U S A (2001) 2.29
High resolution microendoscopy for classification of colorectal polyps. Endoscopy (2013) 2.29
Development and mapping of microsatellite (SSR) markers in wheat. Theor Appl Genet (2005) 2.27
Comparison of five methods for finding conserved sequences in multiple alignments of gene regulatory regions. Nucleic Acids Res (1999) 2.19
env sequences of simian immunodeficiency viruses from chimpanzees in Cameroon are strongly related to those of human immunodeficiency virus group N from the same geographic area. J Virol (2000) 2.17
Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Curr Biol (1997) 2.13
Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds. Antimicrob Agents Chemother (1994) 2.13
Healing of incisional wounds in the embryonic chick wing bud: characterization of the actin purse-string and demonstration of a requirement for Rho activation. J Cell Biol (1996) 2.12
Perfusion of the spleen with blood containing prostaglandin E1: transmitter liberation and uptake. Proc R Soc Lond B Biol Sci (1969) 2.11
Comparison of the Escherichia coli K-12 genome with sampled genomes of a Klebsiella pneumoniae and three salmonella enterica serovars, Typhimurium, Typhi and Paratyphi. Nucleic Acids Res (2000) 2.07
Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006. Ann Oncol (2007) 2.05
A mouse model for beta 0-thalassemia. Proc Natl Acad Sci U S A (1995) 2.01
5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. J Biol Chem (1999) 2.00
The concept of social care and the analysis of contemporary welfare states. Br J Sociol (2000) 1.99
A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J (1994) 1.98
Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Genomics (1999) 1.97
A tool for aligning very similar DNA sequences. Comput Appl Biosci (1997) 1.97
Alignments without low-scoring regions. J Comput Biol (1998) 1.96
Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res (1999) 1.94
Early ear development in the embryo of the zebrafish, Danio rerio. J Comp Neurol (1996) 1.87
Diabetes mellitus: an underestimated public health program. J Chronic Dis (1975) 1.87
Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain. Genome Res (2000) 1.85
A quantitative real-time PCR assay for the identification and enumeration of Alexandrium cysts in marine sediments. Deep Sea Res Part 2 Top Stud Oceanogr (2010) 1.81
Effect of cost on the self-administration and efficacy of nicotine gum: a preliminary study. Prev Med (1991) 1.78
Apoptosis and the cell cycle. Curr Opin Cell Biol (1995) 1.76
Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res (1998) 1.76
The prevalence and prophylaxis of gout in England. J Clin Epidemiol (1995) 1.75
Chaining multiple-alignment blocks. J Comput Biol (1994) 1.75
Genome sequence comparisons: hurdles in the fast lane to functional genomics. Brief Bioinform (2000) 1.71
Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with Drosophila sense-organ development. Development (1998) 1.69
Accuracy of bedside chest hard-copy screen-film versus hard- and soft-copy computed radiographs in a medical intensive care unit: receiver operating characteristic analysis. Radiology (1997) 1.69