Published in Stroke on December 12, 2008
Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke (2009) 6.79
Predicting harms and benefits in translational trials: ethics, evidence, and uncertainty. PLoS Med (2011) 1.52
Middle cerebral artery occlusion model in rodents: methods and potential pitfalls. J Biomed Biotechnol (2011) 1.46
Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism. J Cereb Blood Flow Metab (2010) 1.35
The mdx mouse model as a surrogate for Duchenne muscular dystrophy. FEBS J (2013) 1.34
Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: an experimental study. J Cereb Blood Flow Metab (2011) 1.31
Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS? Br J Pharmacol (2010) 1.12
Improving basic and translational science by accounting for litter-to-litter variation in animal models. BMC Neurosci (2013) 1.12
Rapid brain penetration of interleukin-1 receptor antagonist in rat cerebral ischaemia: pharmacokinetics, distribution, protection. Br J Pharmacol (2010) 1.10
Nonhuman primate models of stroke for translational neuroprotection research. Neurotherapeutics (2012) 1.05
Neuroprotection for stroke: current status and future perspectives. Int J Mol Sci (2012) 1.04
Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing. J Cereb Blood Flow Metab (2010) 1.02
Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies. Exp Transl Stroke Med (2009) 1.01
Methodological quality of preclinical stroke studies is not required for publication in high-impact journals. J Cereb Blood Flow Metab (2010) 0.98
Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies. J Neurochem (2010) 0.97
Successfully Climbing the "STAIRs": Surmounting Failed Translation of Experimental Ischemic Stroke Treatments. Stroke Res Treat (2012) 0.95
Extending clinical equipoise to phase 1 trials involving patients: unresolved problems. Kennedy Inst Ethics J (2010) 0.94
Do stroke models model stroke? Dis Model Mech (2012) 0.91
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas. Invest New Drugs (2012) 0.91
Issues related to development of antiepileptogenic therapies. Epilepsia (2013) 0.91
Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke. Syst Rev (2013) 0.90
Antiepileptic and antiepileptogenic performance of carisbamate after head injury in the rat: blind and randomized studies. J Pharmacol Exp Ther (2010) 0.89
Microfluidic investigation of BDNF-enhanced neural stem cell chemotaxis in CXCL12 gradients. Small (2012) 0.88
Safety and efficacy evaluation of carnosine, an endogenous neuroprotective agent for ischemic stroke. Stroke (2012) 0.88
Method parameters' impact on mortality and variability in rat stroke experiments: a meta-analysis. BMC Neurosci (2013) 0.88
Scope of preclinical testing versus quality control within experiments. Stroke (2009) 0.87
Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research. Exp Transl Stroke Med (2012) 0.86
Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia. Cell Death Dis (2014) 0.86
A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation. Sci Rep (2015) 0.86
GOT to rid the body of excess glutamate. J Cereb Blood Flow Metab (2011) 0.83
Stroke-related translational research. Arch Neurol (2011) 0.83
A nonlinear dynamical theory of cell injury. J Cereb Blood Flow Metab (2012) 0.82
Improving the quality of biomedical research: guidelines for reporting experiments involving animals. J Cereb Blood Flow Metab (2011) 0.82
3D cardiac μtissues within a microfluidic device with real-time contractile stress readout. Lab Chip (2015) 0.82
Animal models of stroke: translational potential at present and in 2050. Future Neurol (2014) 0.81
Biomedical and clinical promises of human pluripotent stem cells for neurological disorders. Biomed Res Int (2013) 0.80
Clinical trial design for endovascular ischemic stroke intervention. Neurology (2012) 0.78
A novel mechanism of neuroprotection: Blood glutamate grabber. J Cereb Blood Flow Metab (2015) 0.77
The NIHSS Score and its Components can Predict Cortical Stroke. J Neurol Disord Stroke (2013) 0.77
Inhibition of glycogen synthase kinase-3β enhances cognitive recovery after stroke: the role of TAK1. Learn Mem (2015) 0.77
Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials. PLoS One (2017) 0.75
Quantifying the behavioural relevance of hippocampal neurogenesis. PLoS One (2014) 0.75
EPO for stroke therapy - Is there a future for further clinical development? Exp Transl Stroke Med (2010) 0.75
Is age a key factor contributing to the disparity between success of neuroprotective strategies in young animals and limited success in elderly stroke patients? Focus on protein homeostasis. J Cereb Blood Flow Metab (2017) 0.75
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron (2011) 18.73
A call for transparent reporting to optimize the predictive value of preclinical research. Nature (2012) 14.63
Stroke. Lancet (2008) 9.51
Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron (2010) 7.87
Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke (2009) 6.79
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature (2013) 4.03
Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev (2009) 3.43
Good laboratory practice: preventing introduction of bias at the bench. Stroke (2008) 3.27
Controversies and priorities in amyotrophic lateral sclerosis. Lancet Neurol (2013) 2.52
Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials. Ann Neurol (2007) 2.46
Granulocyte colony-stimulating factor in patients with acute ischemic stroke: results of the AX200 for Ischemic Stroke trial. Stroke (2013) 2.36
Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging. J Cereb Blood Flow Metab (2003) 2.34
Notes from the field: Heartland virus disease - United States, 2012-2013. MMWR Morb Mortal Wkly Rep (2014) 2.33
Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab (2007) 2.31
Infrared laser therapy for ischemic stroke: a new treatment strategy: results of the NeuroThera Effectiveness and Safety Trial-1 (NEST-1). Stroke (2007) 2.25
Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial. Lancet (2011) 2.16
Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia. Ann Neurol (2004) 2.14
Diagnosis and initial management of cerebellar infarction. Lancet Neurol (2008) 2.08
Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2002) 2.08
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2008) 2.06
HMG-CoA reductase inhibitors improve acute ischemic stroke outcome. Stroke (2005) 2.04
Functional, perfusion and diffusion MRI of acute focal ischemic brain injury. J Cereb Blood Flow Metab (2005) 2.01
Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model. J Neurosci Res (2010) 1.89
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. J Clin Invest (2008) 1.81
Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab (2009) 1.80
Anticoagulation after cardioembolic stroke: to bridge or not to bridge? Arch Neurol (2008) 1.79
The IVH score: a novel tool for estimating intraventricular hemorrhage volume: clinical and research implications. Crit Care Med (2009) 1.73
The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study. Stroke (2012) 1.68
Acute stroke imaging research roadmap. Stroke (2008) 1.66
Electrical impedance myography as a biomarker to assess ALS progression. Amyotroph Lateral Scler (2012) 1.62
Shift analysis versus dichotomization of the modified Rankin scale outcome scores in the NINDS and ECASS-II trials. Stroke (2007) 1.62
Effectiveness and safety of transcranial laser therapy for acute ischemic stroke. Stroke (2009) 1.61
Functional assessments in the rodent stroke model. Exp Transl Stroke Med (2010) 1.61
Aggressive blood pressure-lowering treatment before intravenous tissue plasminogen activator therapy in acute ischemic stroke. Arch Neurol (2008) 1.59
Normobaric hyperoxia delays perfusion/diffusion mismatch evolution, reduces infarct volume, and differentially affects neuronal cell death pathways after suture middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab (2007) 1.57
Differential recovery of behavioral status and brain function assessed with functional magnetic resonance imaging after mild traumatic brain injury in the rat. Crit Care Med (2007) 1.56
Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis. Muscle Nerve (2014) 1.52
Dynamic tracking of acute ischemic tissue fates using improved unsupervised ISODATA analysis of high-resolution quantitative perfusion and diffusion data. J Cereb Blood Flow Metab (2004) 1.52
Acute postischemic renormalization of the apparent diffusion coefficient of water is not associated with reversal of astrocytic swelling and neuronal shrinkage in rats. AJNR Am J Neuroradiol (2002) 1.51
HIV neuropathy in South Africans: frequency, characteristics, and risk factors. Muscle Nerve (2010) 1.51
The Awaji criteria for the diagnosis of amyotrophic lateral sclerosis: have we put the cart before the horse? Muscle Nerve (2010) 1.49
Effects of reperfusion on ADC and CBF pixel-by-pixel dynamics in stroke: characterizing tissue fates using quantitative diffusion and perfusion imaging. J Cereb Blood Flow Metab (2004) 1.49
Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke (2009) 1.48
Reprint: Good laboratory practice: preventing introduction of bias at the bench. J Cereb Blood Flow Metab (2008) 1.47
Acute stroke imaging research roadmap. AJNR Am J Neuroradiol (2008) 1.41
Towards a neuroimaging biomarker for amyotrophic lateral sclerosis. Lancet Neurol (2011) 1.40
Can comprehensive stroke centers erase the 'weekend effect'? Cerebrovasc Dis (2008) 1.39
Developing reference data for nerve conduction studies: an application of quantile regression. Muscle Nerve (2009) 1.39
Outcome analysis in clinical trial design for acute stroke: physicians' attitudes and choices. Cerebrovasc Dis (2008) 1.37
The Virtual International Stroke Trials Archive. Stroke (2007) 1.34
A concerted appeal for international cooperation in preclinical stroke research. Stroke (2013) 1.32
The spot sign in intracerebral hemorrhage: the importance of looking for contrast extravasation. Cerebrovasc Dis (2009) 1.30
Statistical prediction of tissue fate in acute ischemic brain injury. J Cereb Blood Flow Metab (2005) 1.30
Dilemmas in the management of atrial fibrillation in chronic kidney disease. J Am Soc Nephrol (2008) 1.30
Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A (2008) 1.28
Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain. Magn Reson Med (2002) 1.26
International, multicenter randomized preclinical trials in translational stroke research: it's time to act. J Cereb Blood Flow Metab (2012) 1.24
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways. Brain Res (2010) 1.24
Normobaric hyperoxia and delayed tPA treatment in a rat embolic stroke model. J Cereb Blood Flow Metab (2008) 1.24
Therapeutic time window and dose response of autologous bone marrow mononuclear cells for ischemic stroke. J Neurosci Res (2011) 1.24
Thrombolytic therapy for patients who wake-up with stroke. Stroke (2009) 1.23
Utility of axial and radial diffusivity from diffusion tensor MRI as markers of neurodegeneration in amyotrophic lateral sclerosis. Brain Res (2010) 1.22
Partial aortic occlusion for cerebral perfusion augmentation: safety and efficacy of NeuroFlo in Acute Ischemic Stroke trial. Stroke (2011) 1.22
Intracerebral hemorrhage in cocaine users. Stroke (2010) 1.20
AXIS: a trial of intravenous granulocyte colony-stimulating factor in acute ischemic stroke. Stroke (2010) 1.19
The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats. J Neurosci Methods (2003) 1.19
Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians. Neurobiol Aging (2012) 1.18
Effect of the Glycine Antagonist Gavestinel on cerebral infarcts in acute stroke patients, a randomized placebo-controlled trial: The GAIN MRI Substudy. Cerebrovasc Dis (2005) 1.16
Identifying patients at high risk for poor outcome after intra-arterial therapy for acute ischemic stroke. Stroke (2009) 1.15
Bone marrow mononuclear cells protect neurons and modulate microglia in cell culture models of ischemic stroke. J Neurosci Res (2010) 1.15
Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev (2011) 1.11
Differences in ischemic lesion evolution in different rat strains using diffusion and perfusion imaging. Stroke (2005) 1.11
Thymectomy for non-thymomatous myasthenia gravis. Cochrane Database Syst Rev (2013) 1.11
Efficacy and tolerability of levetiracetam in children younger than 4 years: a retrospective review. Epilepsia (2007) 1.10
Laser Doppler flowmetry predicts occlusion but not tPA-mediated reperfusion success after rat embolic stroke. Exp Neurol (2008) 1.09
Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2008) 1.09
Enhancing translation: guidelines for standard pre-clinical experiments in mdx mice. Neuromuscul Disord (2011) 1.08
Valosin-containing protein (VCP) mutations in sporadic amyotrophic lateral sclerosis. Neurobiol Aging (2012) 1.08
Optimizing prediction scores for poor outcome after intra-arterial therapy in anterior circulation acute ischemic stroke. Stroke (2013) 1.07
Zero on the NIHSS does not equal the absence of stroke. Ann Emerg Med (2010) 1.06
Stroke: working toward a prioritized world agenda. Stroke (2010) 1.05
Diffusion tensor imaging reveals regional differences in the cervical spinal cord in amyotrophic lateral sclerosis. Neuroimage (2010) 1.04
Electrical impedance myography correlates with standard measures of ALS severity. Muscle Nerve (2013) 1.03
Microsphere-induced embolic stroke: an MRI study. Magn Reson Med (2004) 1.03
Development, expansion, and use of a stroke clinical trials resource for novel exploratory analyses. Int J Stroke (2012) 1.02
Comprehensive stroke centers and the 'weekend effect': the SPOTRIAS experience. Cerebrovasc Dis (2012) 1.02
Characterizing tissue fate after transient cerebral ischemia of varying duration using quantitative diffusion and perfusion imaging. Stroke (2007) 1.02
Animal models of focal brain ischemia. Exp Transl Stroke Med (2009) 1.01
Stroke: working toward a prioritized world agenda. Cerebrovasc Dis (2010) 1.01
Thrombus burden is associated with clinical outcome after intra-arterial therapy for acute ischemic stroke. Stroke (2008) 1.00
Normobaric hyperoxia - a promising approach to expand the time window for acute stroke treatment. Cerebrovasc Dis (2005) 1.00
The proteasome inhibitor VELCADE reduces infarction in rat models of focal cerebral ischemia. Neurosci Lett (2006) 1.00
Testing for inherited thrombophilias in arterial stroke: can it cause more harm than good? Stroke (2010) 0.99
Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor. Stroke (2011) 0.98
Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics (2011) 0.98
The University of Texas Houston Stroke Registry (UTHSR): implementation of enhanced data quality assurance procedures improves data quality. BMC Neurol (2013) 0.97