Published in J Trauma on December 01, 2008
Inflammation and the Host Response to Injury (Trauma) | NCT00257231
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med (2012) 2.17
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg (2012) 2.07
Acute respiratory distress syndrome after trauma: development and validation of a predictive model. Crit Care Med (2012) 1.62
An International Normalized Ratio-Based Definition of Acute Traumatic Coagulopathy Is Associated With Mortality, Venous Thromboembolism, and Multiple Organ Failure After Injury. Crit Care Med (2015) 1.56
Traumatic injury, early gene expression, and gram-negative bacteremia. Crit Care Med (2014) 1.45
Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure. Shock (2010) 1.16
Relationship between feeding tube site and respiratory outcomes. JPEN J Parenter Enteral Nutr (2011) 1.04
Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism? J Trauma Acute Care Surg (2013) 0.83
Experience with an enteral-based nutritional support regimen in critically ill trauma patients. J Am Coll Surg (2013) 0.82
Genomics of injury: The Glue Grant experience. J Trauma Acute Care Surg (2015) 0.82
Bench-to-bedside review: Burn-induced cerebral inflammation--a neglected entity? Crit Care (2009) 0.82
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med (2005) 23.85
Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis (2006) 14.63
Nosocomial infections in medical intensive care units in the United States. National Nosocomial Infections Surveillance System. Crit Care Med (1999) 7.90
Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia. Chest (2003) 5.64
Eliminating catheter-related bloodstream infections in the intensive care unit. Crit Care Med (2004) 5.47
Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis (2001) 4.94
Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA (2003) 4.84
Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis (2003) 2.92
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients. Crit Care Med (1997) 2.64
Increasing prevalence and severity of Clostridium difficile colitis in hospitalized patients in the United States. Arch Surg (2007) 2.55
National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002, issued August 2002. Am J Infect Control (2002) 2.49
An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study. Intensive Care Med (2006) 2.00
Complicated infections of skin and skin structures: when the infection is more than skin deep. J Antimicrob Chemother (2004) 1.74
In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin-structure infections and complicated intra-abdominal infections. Clin Infect Dis (2005) 1.73
Source control in the management of severe sepsis and septic shock: an evidence-based review. Crit Care Med (2004) 1.65
Double-blind placebo-controlled trial of fluconazole to prevent candidal infections in critically ill surgical patients. Ann Surg (2001) 1.63
The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: an executive summary. Surg Infect (Larchmt) (2002) 1.47
Antibiotic treatment for surgical peritonitis. Ann Surg (1991) 1.44
A review. Lessons from an animal model of intra-abdominal sepsis. Arch Surg (1978) 1.33
Prophylaxis of Candida infections in adult trauma and surgical intensive care patients: a systematic review and meta-analysis. Intensive Care Med (2005) 1.30
Antimicrobial therapy for patients with severe sepsis and septic shock: an evidence-based review. Crit Care Med (2004) 1.15
Antimicrobial management of complicated skin and skin structure infections in the era of emerging resistance. Surg Infect (Larchmt) (2005) 1.11
Diagnosis of infection in sepsis: an evidence-based review. Crit Care Med (2004) 1.01
Randomized controlled trial of moxifloxacin compared with piperacillin-tazobactam and amoxicillin-clavulanate for the treatment of complicated intra-abdominal infections. Ann Surg (2006) 0.99
A practical guide to the treatment of complicated skin and soft tissue infections. Drugs (2003) 0.98
Nosocomial infections adversely affect the outcomes of patients with serious intraabdominal infections. Surg Infect (Larchmt) (2004) 0.95
Antibiotics in trauma and orthopedic surgery -- a primer of evidence-based recommendations. Injury (2006) 0.91
The implications of enterococci for the intensive care unit. Crit Care Resusc (2007) 0.91
De-escalation therapy in ventilator-associated pneumonia. Curr Opin Crit Care (2006) 0.90
Intra-abdominal infections. Microbes Infect (2004) 0.88
The diagnostic value of fungal surveillance cultures in critically ill patients. Surg Infect (Larchmt) (2000) 0.85
Ventilator-associated pneumonia: insights from recent clinical trials. Chest (2005) 0.85
Relevance and utility of peritoneal cultures in patients with peritonitis. Surg Infect (Larchmt) (2001) 0.83
Coverage of enterococci in community acquired secondary peritonitis: results of a randomized trial. Surg Infect (Larchmt) (2000) 0.83
Clinical and scientific importance of source control in abdominal infections: summary of a symposium. Can J Surg (1999) 0.82
Antibiotic-resistant organisms among long-term care facility residents on admission to an inpatient geriatrics unit: Retrospective and prospective surveillance. Am J Infect Control (2001) 0.81
Management of infection in the surgical patient: an update. Surg Technol Int (2003) 0.78
Hospital-acquired infections in the surgical intensive care: epidemiology and prevention. Zentralbl Chir (2003) 0.78
Nosocomial infections in neurocritical care. Curr Neurol Neurosci Rep (2006) 0.77
Treatment of ventilator-associated pneumonia: get it right from the start. Crit Care Med (2003) 0.77
Recent developments in clinical management of surgical sepsis. Curr Opin Crit Care (2001) 0.76
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
A national evaluation of the effect of trauma-center care on mortality. N Engl J Med (2006) 9.74
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis (2010) 6.59
Trial of short-course antimicrobial therapy for intraabdominal infection. N Engl J Med (2015) 5.21
Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications. Ann Surg (2002) 4.91
A subclavian artery injury, secondary to internal jugular vein cannulation, is a predictable right-sided phenomenon. Anesth Analg (2002) 4.35
Disparities in liver transplantation before and after introduction of the MELD score. JAMA (2008) 4.10
Transfusion-related acute lung injury: definition and review. Crit Care Med (2005) 3.98
Emergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohort. Ann Emerg Med (2009) 3.92
Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients. Crit Care Med (2013) 3.65
Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A (2005) 3.49
Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics (2004) 3.22
Randomized comparison of ABVD and MOPP/ABV hybrid for the treatment of advanced Hodgkin's disease: report of an intergroup trial. J Clin Oncol (2003) 3.00
Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis (2003) 2.92
Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial. Ann Surg (2011) 2.85
Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program. Ann Surg (2008) 2.82
A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. Crit Care Med (2014) 2.77
Western Trauma Association critical decisions in trauma: management of complicated diverticulitis. J Trauma Acute Care Surg (2012) 2.77
Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt) (2010) 2.67
Effect of delay to operation on outcomes in adults with acute appendicitis. Arch Surg (2010) 2.53
Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer? J Trauma (2008) 2.52
Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202). J Clin Oncol (2013) 2.50
Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma (2009) 2.49
The role of REBOA in the control of exsanguinating torso hemorrhage. J Trauma Acute Care Surg (2015) 2.48
Barriers to the participation of African-American patients with cancer in clinical trials: a pilot study. Cancer (2003) 2.39
Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg (2002) 2.34
Improving accrual of older persons to cancer treatment trials: a randomized trial comparing an educational intervention with standard information: CALGB 360001. J Clin Oncol (2005) 2.34
Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion. J Trauma Acute Care Surg (2012) 2.32
Tranexamic acid in trauma: how should we use it? J Trauma Acute Care Surg (2013) 2.32
Public bicycle share programs and head injuries. Am J Public Health (2014) 2.30
Management of severe head injury: institutional variations in care and effect on outcome. Crit Care Med (2002) 2.27
A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med (2011) 2.27
Predictors of mortality and limb loss in necrotizing soft tissue infections. Arch Surg (2005) 2.27
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol Med (2006) 2.27
The injured child is resistant to multiple organ failure: a different inflammatory response? J Trauma (2002) 2.26
High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics (2006) 2.25
Timing of intubation and ventilator-associated pneumonia following injury. Arch Surg (2010) 2.23
Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis. J Trauma (2003) 2.23
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med (2012) 2.17
Active surveillance cultures of methicillin-resistant Staphylococcus aureus as a tool to predict methicillin-resistant S. aureus ventilator-associated pneumonia. Crit Care Med (2012) 2.17
Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift. J Trauma (2007) 2.15
An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma (2008) 2.15
Acute care surgery: Eraritjaritjaka. J Am Coll Surg (2006) 2.12
Characterization of the gender dimorphism after injury and hemorrhagic shock: are hormonal differences responsible? Crit Care Med (2008) 2.10
What is the most cost-effective treatment for 1 to 2-cm bulbar urethral strictures: societal approach using decision analysis. Urology (2006) 2.09
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg (2012) 2.07
Effect of blood products transfusion on the development of postinjury multiple organ failure. Arch Surg (2010) 2.04
Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients. Arch Surg (2010) 2.03
Posttraumatic pneumatocele. J Am Coll Surg (2005) 2.02
Patterns of errors contributing to trauma mortality: lessons learned from 2,594 deaths. Ann Surg (2006) 2.02