cGMP and cGMP-dependent protein kinase in platelets and blood cells.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMID 19089344)

Published in Handb Exp Pharmacol on January 01, 2009

Authors

Ulrich Walter1, Stepan Gambaryan

Author Affiliations

1: Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg, 97080, Germany. uwalter@klin-biochem.uni-wuerzburg.de

Articles citing this

cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol Rev (2010) 3.27

Thrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFkappaB-IkappaB complex. J Biol Chem (2010) 1.47

The multiple actions of NO. Pflugers Arch (2009) 1.05

Role of blood cells in ischaemia-reperfusion induced endothelial barrier failure. Cardiovasc Res (2010) 1.03

The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells. Br J Pharmacol (2012) 0.88

Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway. PLoS One (2012) 0.85

Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury. Stroke (2010) 0.84

Probing domain interactions in soluble guanylate cyclase. Biochemistry (2011) 0.82

Cordycepin-Enriched WIB801C from Cordyceps militaris Inhibits Collagen-Induced [Ca(2+)]i Mobilization via cAMP-Dependent Phosphorylation of Inositol 1, 4, 5-Trisphosphate Receptor in Human Platelets. Biomol Ther (Seoul) (2014) 0.81

From bedside to bench-meeting report of the 7th International Conference on cGMP "cGMP: generators, effectors and therapeutic implications" in Trier, Germany, from June 19th to 21st 2015. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.80

Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis. Exp Hematol (2012) 0.78

Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis. Cell Commun Signal (2016) 0.77

TM-1-1DP exerts protective effect against myocardial ischemia reperfusion injury via AKT-eNOS pathway. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.77

The sGC stimulator riociguat inhibits platelet function in washed platelets but not in whole blood. Br J Pharmacol (2015) 0.76

Can erythrocytes release biologically active NO? Cell Commun Signal (2016) 0.75

Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha). Biochim Biophys Acta (2010) 0.75

Protein Kinase G facilitates EGFR-mediated cell death in MDA-MB-468 cells. Exp Cell Res (2016) 0.75

Articles by these authors

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood (2012) 2.47

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases. Kidney Int (2010) 2.11

Fluorescent sensors for rapid monitoring of intracellular cGMP. Nat Methods (2006) 1.96

Single L-type Ca(2+) channel regulation by cGMP-dependent protein kinase type I in adult cardiomyocytes from PKG I transgenic mice. Cardiovasc Res (2003) 1.51

Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. J Biol Chem (2004) 1.30

Phosphoproteome of resting human platelets. J Proteome Res (2007) 1.24

Interaction of the plasma membrane Ca2+ pump 4b/CI with the Ca2+/calmodulin-dependent membrane-associated kinase CASK. J Biol Chem (2003) 1.19

Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes. Hypertension (2002) 1.16

Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146. J Biol Chem (2003) 1.16

Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. Blood (2005) 1.15

The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in mice. J Clin Invest (2009) 1.13

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase. Biochem Biophys Res Commun (2004) 1.12

Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. Am J Physiol Heart Circ Physiol (2003) 1.04

The heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansion. Endocrinology (2008) 0.99

What can proteomics tell us about platelets? Circ Res (2014) 0.95

Thrombin stimulation of p38 MAP kinase in human platelets is mediated by ADP and thromboxane A2 and inhibited by cGMP/cGMP-dependent protein kinase. Blood (2006) 0.93

Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation. J Cell Biochem (2007) 0.92

Increased effects of C-type natriuretic peptide on cardiac ventricular contractility and relaxation in guanylyl cyclase A-deficient mice. Cardiovasc Res (2002) 0.91

Cyclic nucleotide-regulated proliferation and differentiation vary in human hematopoietic progenitor cells derived from healthy persons, tumor patients, and chronic myelocytic leukemia patients. Stem Cells Dev (2008) 0.91

Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS. Blood Cells Mol Dis (2006) 0.91

Heme oxygenase-1 inhibition of MAP kinases, calcineurin/NFAT signaling, and hypertrophy in cardiac myocytes. Cardiovasc Res (2004) 0.90

L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in rats. Kidney Int (2003) 0.90

Vasodilator-stimulated phosphoprotein-deficient mice demonstrate increased platelet activation but improved renal endothelial preservation and regeneration in passive nephrotoxic nephritis. J Am Soc Nephrol (2005) 0.89

Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways. Blood (2013) 0.87

Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor. J Biol Chem (2007) 0.86

Increased effects of C-type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP-dependent protein kinase I. Br J Pharmacol (2003) 0.86

Response: platelet transcriptome and proteome--relation rather than correlation. Blood (2013) 0.86

Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors. Clin Chem Lab Med (2012) 0.85

Determination of ATP and ADP Secretion from Human and Mouse Platelets by an HPLC Assay. Transfus Med Hemother (2013) 0.84

Increased sensitivity to endothelial nitric oxide (NO) contributes to arterial normotension in mice with vascular smooth muscle-selective deletion of the atrial natriuretic peptide (ANP) receptor. J Biol Chem (2003) 0.83

Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA. J Am Soc Nephrol (2003) 0.82

Phosphoproteomics of human platelets: A quest for novel activation pathways. Biochim Biophys Acta (2006) 0.82

Roles of cGMP/cGMP-dependent protein kinase in platelet activation. Blood (2004) 0.82

Lack of effect of ODQ does not exclude cGMP signalling via NO-sensitive guanylyl cyclase. Br J Pharmacol (2013) 0.81

Phosphatidylserine surface expression and integrin alpha IIb beta 3 activity on thrombin/convulxin stimulated platelets/particles of different sizes. Br J Haematol (2008) 0.81

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy. Cell Commun Signal (2013) 0.81

Integrin-dependent translocation of LASP-1 to the cytoskeleton of activated platelets correlates with LASP-1 phosphorylation at tyrosine 171 by Src-kinase. Thromb Haemost (2009) 0.79

L-Arginine does not affect renal morphology and cell survival in ischemic acute renal failure in rats. Nephron Physiol (2005) 0.79

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy. J Transl Med (2012) 0.78

Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis. Exp Hematol (2012) 0.78

Prostaglandin E2 inhibits vasotocin-induced osmotic water permeability in the frog urinary bladder by EP1-receptor-mediated activation of NO/cGMP pathway. Am J Physiol Regul Integr Comp Physiol (2007) 0.77

Frog urinary bladder epithelial cells express TLR4 and respond to bacterial LPS by increase of iNOS expression and L-arginine uptake. Am J Physiol Regul Integr Comp Physiol (2012) 0.77

The Thr715Pro variant impairs terminal glycosylation of P-selectin. Thromb Haemost (2012) 0.77

Human blood platelets lack nitric oxide synthase activity. Platelets (2014) 0.76

Does the NO/sGC/cGMP/PKG pathway play a stimulatory role in platelets? Blood (2012) 0.76

Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways. Thromb Haemost (2011) 0.76

The thrombin inhibitors hirudin and Refludan(®) activate the soluble guanylyl cyclase and the cGMP pathway in washed human platelets. Thromb Haemost (2012) 0.76

A comparative analysis of the bistability switch for platelet aggregation by logic ODE based dynamical modeling. Mol Biosyst (2014) 0.75

Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B. Thromb Haemost (2017) 0.75

Potential pitfalls with the use of acetoxy (CH(3)COO) drugs in studies on nitric oxide synthase in platelets. Nitric Oxide (2012) 0.75

Immune escape of AKT overexpressing ovarian cancer cells. Int J Oncol (2013) 0.75