|
1
|
Genetic basis for individual variations in pain perception and the development of a chronic pain condition.
|
Hum Mol Genet
|
2004
|
5.87
|
|
2
|
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
|
Nat Med
|
2006
|
3.38
|
|
3
|
Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli.
|
Pain
|
2006
|
2.75
|
|
4
|
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.
|
Brain
|
2010
|
2.41
|
|
5
|
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
|
Cell
|
2010
|
2.37
|
|
6
|
Association of catechol-O-methyltransferase genetic variants with outcome in patients undergoing surgical treatment for lumbar degenerative disc disease.
|
Spine J
|
2010
|
1.98
|
|
7
|
Pain perception is altered by a nucleotide polymorphism in SCN9A.
|
Proc Natl Acad Sci U S A
|
2010
|
1.79
|
|
8
|
Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms.
|
Clin Chem
|
2007
|
1.64
|
|
9
|
Persistent pain in postmastectomy patients: comparison of psychophysical, medical, surgical, and psychosocial characteristics between patients with and without pain.
|
Pain
|
2012
|
1.62
|
|
10
|
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
|
Hum Mol Genet
|
2008
|
1.59
|
|
11
|
Three major haplotypes of the beta2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder.
|
Am J Med Genet B Neuropsychiatr Genet
|
2006
|
1.50
|
|
12
|
Genetic basis of pain variability: recent advances.
|
J Med Genet
|
2011
|
1.14
|
|
13
|
Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction.
|
Nat Neurosci
|
2011
|
1.13
|
|
14
|
Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans.
|
Pharmacogenet Genomics
|
2005
|
1.10
|
|
15
|
Effects of a alpha 2C-adrenoreceptor gene polymorphism on neural responses to facial expressions in depression.
|
Neuropsychopharmacology
|
2006
|
1.08
|
|
16
|
μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer.
|
Anesthesiology
|
2012
|
1.03
|
|
17
|
Alteration in pain modulation in women with persistent pain after lumpectomy: influence of catastrophizing.
|
J Pain Symptom Manage
|
2012
|
0.99
|
|
18
|
A clinical genetic method to identify mechanisms by which pain causes depression and anxiety.
|
Mol Pain
|
2006
|
0.99
|
|
19
|
Integration of pain score and morphine consumption in analgesic clinical studies.
|
J Pain
|
2013
|
0.88
|
|
20
|
Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.
|
PLoS Genet
|
2012
|
0.84
|
|
21
|
Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?
|
Mol Pain
|
2007
|
0.83
|
|
22
|
Polymorphic variation of the guanosine triphosphate cyclohydrolase 1 gene predicts outcome in patients undergoing surgical treatment for lumbar degenerative disc disease.
|
Spine (Phila Pa 1976)
|
2010
|
0.81
|
|
23
|
Predicting, preventing and managing persistent pain after breast cancer surgery: the importance of psychosocial factors.
|
Pain Manag
|
2014
|
0.80
|
|
24
|
Chronic pain after lower abdominal surgery: do catechol-O-methyl transferase/opioid receptor μ-1 polymorphisms contribute?
|
Mol Pain
|
2013
|
0.78
|
|
25
|
Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease.
|
Clin J Pain
|
2015
|
0.75
|
|
26
|
Labor pain mechanisms.
|
Int Anesthesiol Clin
|
2014
|
0.75
|