Published in Hum Mol Genet on November 10, 2004
Pharmacogenetic Morphine Spine Study | NCT01839461
Study of Orofacial Pain and PropRANOlol (SOPPRANO) | NCT02437383
Patient Controlled Analgesia Pharmacogenetic Study | NCT01731873
Multicenter Perioperative Opioid Pharmacogenetic Study | NCT01495611
Breastfeeding Self-Management for Nipple and Breast Pain (BSM) | NCT03392675
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery | NCT04031716
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain (CT-Pain) | NCT04798573
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Adrenergic dysregulation and pain with and without acute beta-blockade in women with fibromyalgia and temporomandibular disorder. J Pain (2009) 1.20
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Variations in catechol-O-methyltransferase gene interact with parenting to influence attention in early development. Neuroscience (2009) 1.16
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Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia. PLoS One (2011) 1.04
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Pain modality- and sex-specific effects of COMT genetic functional variants. Pain (2013) 1.02
Orthodontic Treatment, Genetic Factors and Risk of Temporomandibular Disorder. Semin Orthod (2008) 1.01
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No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol-O-methyltransferase gene. The HUNT study. BMC Musculoskelet Disord (2006) 0.98
Elevated pain sensitivity in chronic pain patients at risk for opioid misuse. J Pain (2011) 0.98
Abnormal pain modulation in patients with spatially distributed chronic pain: fibromyalgia. Rheum Dis Clin North Am (2009) 0.98
Genetic influences on the dynamics of pain and affect in fibromyalgia. Health Psychol (2010) 0.97
The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli. PLoS One (2011) 0.97
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Estrogen receptor-alpha polymorphisms and predisposition to TMJ disorder. J Pain (2009) 0.97
Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. Arthritis Rheum (2012) 0.97
Genetic contributions to pain: a review of findings in humans. Oral Dis (2008) 0.96
Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. BMC Genomics (2007) 0.95
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Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50
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A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action. Biol Direct (2006) 11.31
Serotonin transporter genetic variation and the response of the human amygdala. Science (2002) 9.31
Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature (2007) 8.03
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2008) 7.65
Parental origin of sequence variants associated with complex diseases. Nature (2009) 7.21
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet (2009) 6.91
Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet (2008) 6.69
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet (2006) 6.27
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet (2009) 5.06
Trends in access to health services and financial protection in China between 2003 and 2011: a cross-sectional study. Lancet (2012) 4.98
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry (2008) 4.91
Fine-scale recombination rate differences between sexes, populations and individuals. Nature (2010) 4.74
COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science (2003) 4.72
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A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet (2011) 3.94
An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol Clin Exp Res (2005) 3.94
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Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet (2009) 3.46
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To retain or remove user fees?: reflections on the current debate in low- and middle-income countries. Appl Health Econ Health Policy (2006) 3.06
Mutations in BRIP1 confer high risk of ovarian cancer. Nat Genet (2011) 3.06
Genetic correction of PSA values using sequence variants associated with PSA levels. Sci Transl Med (2010) 2.83
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Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain (2006) 2.75
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet (2010) 2.75
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet (2004) 2.71
Idiopathic pain disorders--pathways of vulnerability. Pain (2006) 2.69
Genetic variation in human NPY expression affects stress response and emotion. Nature (2008) 2.65
Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation. Science (2010) 2.62
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet (2002) 2.60
Preventing impoverishment through protection against catastrophic health expenditure. Bull World Health Organ (2002) 2.56
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nat Genet (2010) 2.56
Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits. Nature (2013) 2.55
Parental perceptions of children's oral health: the Early Childhood Oral Health Impact Scale (ECOHIS). Health Qual Life Outcomes (2007) 2.55
Perceived intensity and unpleasantness of cutaneous and auditory stimuli: an evaluation of the generalized hypervigilance hypothesis. Pain (2009) 2.55
The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics (2004) 2.54
Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2). Pain (2009) 2.53
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am J Psychiatry (2002) 2.51
Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques. Biol Psychiatry (2004) 2.49
A 160-kilobit molecular electronic memory patterned at 10(11) bits per square centimetre. Nature (2007) 2.48
Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with pain. Pain (2007) 2.47
How do age and tooth loss affect oral health impacts and quality of life? A study comparing two national samples. Community Dent Oral Epidemiol (2004) 2.47
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain (2010) 2.41
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell (2010) 2.37
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A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer. Nat Genet (2012) 2.29
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med (2012) 2.25
Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendations. Pain (2006) 2.23
The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption. PLoS Med (2009) 2.20
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Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex. J Neurosci (2005) 2.04
Parental perceptions of their preschool-aged children's oral health. J Am Dent Assoc (2005) 2.04
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A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature (2010) 2.00
Use of the cumulative proportion of responders analysis graph to present pain data over a range of cut-off points: making clinical trial data more understandable. J Pain Symptom Manage (2006) 1.99
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