Published in Toxicol Lett on December 07, 2008
Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice. Part Fibre Toxicol (2010) 1.29
Titanium dioxide in our everyday life; is it safe? Radiol Oncol (2011) 1.22
Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: short and long-term studies in mice. Nanotoxicology (2010) 1.20
Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: a toxicogenomic study. Environ Mol Mutagen (2011) 1.16
Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats. Part Fibre Toxicol (2014) 1.11
Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring. Nanotoxicology (2011) 1.02
Physicochemical characteristics of nanomaterials that affect pulmonary inflammation. Part Fibre Toxicol (2014) 1.01
Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms. Part Fibre Toxicol (2011) 0.98
Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials. Part Fibre Toxicol (2014) 0.98
Rat pulmonary responses to inhaled nano-TiO₂: effect of primary particle size and agglomeration state. Part Fibre Toxicol (2013) 0.86
An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials. J Nanobiotechnology (2016) 0.80
Translocation of particles deposited in the respiratory system: a systematic review and statistical analysis. Environ Health Prev Med (2011) 0.79
Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat. Part Fibre Toxicol (2015) 0.79
Bayesian evaluation of a physiologically-based pharmacokinetic (PBPK) model of long-term kinetics of metal nanoparticles in rats. Regul Toxicol Pharmacol (2015) 0.77
Systemic immune effects of titanium dioxide nanoparticles after repeated intratracheal instillation in rat. Int J Mol Sci (2014) 0.77
Nasal and pulmonary toxicity of titanium dioxide nanoparticles in rats. Toxicol Res (2012) 0.76
Surface modification does not influence the genotoxic and inflammatory effects of TiO2 nanoparticles after pulmonary exposure by instillation in mice. Mutagenesis (2016) 0.75
Comparative short-term inhalation toxicity of five organic diketopyrrolopyrrole pigments and two inorganic iron-oxide-based pigments. Inhal Toxicol (2016) 0.75
Histomorphological evaluation of maternal and neonatal distal airspaces after maternal intake of nanoparticulate titanium dioxide: an experimental study in Wistar rats. J Mol Histol (2013) 0.75
Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci (2009) 3.06
Testing metal-oxide nanomaterials for human safety. Adv Mater (2010) 1.78
Non-animal test methods for predicting skin sensitization potentials. Arch Toxicol (2012) 1.54
Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. Arch Toxicol (2007) 1.30
A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. ACS Nano (2013) 1.20
Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance. Inhal Toxicol (2009) 1.18
Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black. Part Fibre Toxicol (2013) 1.17
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*. ALTEX (2012) 1.15
Acute and chronic effects of nano- and non-nano-scale TiO(2) and ZnO particles on mobility and reproduction of the freshwater invertebrate Daphnia magna. Chemosphere (2009) 1.14
On the lifecycle of nanocomposites: comparing released fragments and their in-vivo hazards from three release mechanisms and four nanocomposites. Small (2011) 1.11
Concern-driven integrated approaches to nanomaterial testing and assessment--report of the NanoSafety Cluster Working Group 10. Nanotoxicology (2013) 1.10
Contribution of new technologies to characterization and prediction of adverse effects. Crit Rev Toxicol (2015) 1.08
Toxico-/biokinetics of nanomaterials. Arch Toxicol (2012) 1.08
Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies. Arch Toxicol (2012) 0.99
Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials. Part Fibre Toxicol (2014) 0.98
Putting the parts together: combining in vitro methods to test for skin sensitizing potentials. Regul Toxicol Pharmacol (2012) 0.94
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. ALTEX (2014) 0.94
Metabolomics in toxicology and preclinical research. ALTEX (2013) 0.93
Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data. Part Fibre Toxicol (2013) 0.91
Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo. Eur J Pharm Sci (2011) 0.90
Elastic CNT-polyurethane nanocomposite: synthesis, performance and assessment of fragments released during use. Nanoscale (2012) 0.90
Integrated Testing Strategies (ITS) for safety assessment. ALTEX (2014) 0.89
Linking energy metabolism to dysfunctions in mitochondrial respiration--a metabolomics in vitro approach. Toxicol Lett (2011) 0.89
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I). Exp Dermatol (2012) 0.88
Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria. Arch Toxicol (2014) 0.88
In-house validation of the EpiOcular(TM) eye irritation test and its combination with the bovine corneal opacity and permeability test for the assessment of ocular irritation. Altern Lab Anim (2011) 0.87
t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials. ALTEX (2011) 0.87
Drug-metabolizing enzymes in the skin of man, rat, and pig. Drug Metab Rev (2007) 0.87
Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats. Mutat Res (2011) 0.86
Skin sensitisation--moving forward with non-animal testing strategies for regulatory purposes in the EU. Regul Toxicol Pharmacol (2013) 0.86
Feasibility Assessment of Micro-Electrode Chip Assay as a Method of Detecting Neurotoxicity in vitro. Front Neuroeng (2011) 0.86
In vivo-in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems. Toxicol In Vitro (2012) 0.83
Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies. Nanomedicine (Lond) (2014) 0.82
Genotoxicity investigations on nanomaterials. Arch Toxicol (2012) 0.82
Effects of estrogen coadministration on epoxiconazole toxicity in rats. Birth Defects Res B Dev Reprod Toxicol (2013) 0.80
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals. Toxicol In Vitro (2011) 0.80
Short-term rat inhalation study with aerosols of acrylic ester-based polymer dispersions containing a fraction of nanoparticles. Int J Toxicol (2012) 0.80
Esterase activity in excised and reconstructed human skin--biotransformation of prednicarbate and the model dye fluorescein diacetate. Eur J Pharm Biopharm (2012) 0.80
Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency. Toxicol In Vitro (2012) 0.80
Additional histopathologic examination of the lungs from a 3-month inhalation toxicity study with multiwall carbon nanotubes in rats. Toxicol Sci (2013) 0.80
Gene toxicity studies on titanium dioxide and zinc oxide nanomaterials used for UV-protection in cosmetic formulations. Nanotoxicology (2010) 0.80
Effects of SiO₂, ZrO₂, and BaSO₄ nanomaterials with or without surface functionalization upon 28-day oral exposure to rats. Arch Toxicol (2014) 0.80
Extrahepatic metabolism at the body's internal-external interfaces. Drug Metab Rev (2014) 0.79
Deposition behavior of inhaled nanostructured TiO2 in rats: fractions of particle diameter below 100 nm (nanoscale) and the slicing bias of transmission electron microscopy. Inhal Toxicol (2012) 0.79
Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance. Regul Toxicol Pharmacol (2013) 0.79
Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2012) 0.79
A testing strategy for the identification of mammalian, systemic endocrine disruptors with particular focus on steroids. Regul Toxicol Pharmacol (2012) 0.78
Lymphadenopathy and diarrhea in a Miniature Schnauzer. Vet Clin Pathol (2002) 0.78
Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data. Altern Lab Anim (2011) 0.78
Epoxiconazole-induced degeneration in rat placenta and the effects of estradiol supplementation. Birth Defects Res B Dev Reprod Toxicol (2013) 0.78
Hyperplasia of the lymphoepithelium of NALT in rats but not in mice upon 28-day exposure to 15 ppm formaldehyde vapor. Exp Toxicol Pathol (2009) 0.77
Nanostructured calcium silicate hydrate seeds accelerate concrete hardening: a combined assessment of benefits and risks. Arch Toxicol (2012) 0.77
Dispersing perylene diimide/SWCNT hybrids: structural insights at the molecular level and fabricating advanced materials. J Am Chem Soc (2015) 0.77
Inhalation of formaldehyde does not induce systemic genotoxic effects in rats. Mutat Res (2009) 0.77
Performance standards and alternative assays: practical insights from skin sensitization. Regul Toxicol Pharmacol (2012) 0.77
Influence of dispersive agent on nanomaterial agglomeration and implications for biological effects in vivo or in vitro. Toxicol In Vitro (2015) 0.77
Species differences in developmental toxicity of epoxiconazole and its relevance to humans. Birth Defects Res B Dev Reprod Toxicol (2013) 0.77
The bovine corneal opacity and permeability test in routine ocular irritation testing and its improvement within the limits of OECD test guideline 437. Altern Lab Anim (2011) 0.76
Chemical toxicity testing in vitro using cytochrome P450-expressing cell lines, such as human CYP1B1. Nat Protoc (2011) 0.76
Relevance of xenobiotic enzymes in human skin in vitro models to activate pro-sensitizers. J Immunotoxicol (2012) 0.76
Erratum to "Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies" [Regul. Toxicol. Pharmacol. (2012) 402-414]. Regul Toxicol Pharmacol (2013) 0.76
Vinclozolin: a feasibility and sensitivity study of the ILSI-HESI F1-extended one-generation rat reproduction protocol. Regul Toxicol Pharmacol (2010) 0.76
Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models. Toxicol In Vitro (2011) 0.76
Genotoxicity of nanomaterials: refining strategies and tests for hazard identification. Environ Mol Mutagen (2013) 0.75
Health and nutritional status of Wistar rats following subchronic exposure to CV127 soybeans. Food Chem Toxicol (2011) 0.75
Best practices for clinical pathology testing in carcinogenicity studies. Toxicol Pathol (2011) 0.75
Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies. Regul Toxicol Pharmacol (2012) 0.75
Experience with the HET-CAM method in the routine testing of a broad variety of chemicals and formulations. Altern Lab Anim (2010) 0.75
Polyethylene glycol-polyvinyl alcohol grafted copolymer: study of the bioavailability after oral administration to rats. Food Chem Toxicol (2013) 0.75