Published in Neurobiol Aging on December 31, 2008
Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome. J Neurochem (2010) 1.08
The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions. Front Aging Neurosci (2011) 0.86
Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function. J Physiol (2015) 0.82
Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice. Biol Psychiatry (2015) 0.80
Quantitative profiling of brain lipid raft proteome in a mouse model of fragile X syndrome. PLoS One (2015) 0.78
Decreases in plasma membrane Ca²⁺-ATPase in brain synaptic membrane rafts from aged rats. J Neurochem (2012) 0.78
Citrulline diet supplementation improves specific age-related raft changes in wild-type rodent hippocampus. Age (Dordr) (2012) 0.76
Lipid rafts and signal transduction. Nat Rev Mol Cell Biol (2000) 25.87
The International Protein Index: an integrated database for proteomics experiments. Proteomics (2004) 14.67
Gene-expression profile of the ageing brain in mice. Nat Genet (2000) 5.46
Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors. Proc Natl Acad Sci U S A (2003) 4.87
A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics (2003) 3.57
Localizing NADPH oxidase-derived ROS. Sci STKE (2006) 2.91
Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. J Biol Chem (2004) 2.84
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J Neurosci (2003) 2.80
Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. Science (1989) 2.61
The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat Neurosci (1999) 2.32
Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging (2002) 2.06
Novel roles for mammalian septins: from vesicle trafficking to oncogenesis. J Cell Sci (2001) 1.74
Comparison of protein precipitation methods for sample preparation prior to proteomic analysis. J Chromatogr A (2004) 1.72
Calcium hypothesis of Alzheimer's disease and brain aging. Ann N Y Acad Sci (1994) 1.69
Here come the septins: novel polymers that coordinate intracellular functions and organization. J Cell Sci (2006) 1.60
Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. J Neural Transm Suppl (2000) 1.54
Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release. J Cell Biol (2004) 1.48
Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo. Chem Res Toxicol (2008) 1.37
Lipid rafts-protein association and the regulation of protein activity. Arch Biochem Biophys (2004) 1.37
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc Natl Acad Sci U S A (2006) 1.35
Cholesterol depletion of enterocytes. Effect on the Golgi complex and apical membrane trafficking. J Biol Chem (2000) 1.33
Proteome analysis reveals phosphorylation of ATP synthase beta -subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes. J Biol Chem (2003) 1.28
Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells. Mol Biol Cell (2007) 1.26
Lipid raft proteome reveals ATP synthase complex in the cell surface. Proteomics (2004) 1.25
VDAC1 is a transplasma membrane NADH-ferricyanide reductase. J Biol Chem (2003) 1.21
Organelle proteomics of rat synaptic proteins: correlation-profiling by isotope-coded affinity tagging in conjunction with liquid chromatography-tandem mass spectrometry to reveal post-synaptic density specific proteins. J Proteome Res (2005) 1.17
Calorie restriction attenuates age-related alterations in the plasma membrane antioxidant system in rat liver. Exp Gerontol (2004) 1.17
Synaptic remodeling during aging and in Alzheimer's disease. J Alzheimers Dis (2006) 1.10
Regulation of AMPA receptor localization in lipid rafts. Mol Cell Neurosci (2008) 1.07
Porin is present in the plasma membrane where it is concentrated in caveolae and caveolae-related domains. J Biol Chem (1999) 1.06
Oxidation-reduction respiratory chains and ATP synthase complex are localized in detergent-resistant lipid rafts. Proteomics (2006) 1.06
Lipid raft proteomics: analysis of in-solution digest of sodium dodecyl sulfate-solubilized lipid raft proteins by liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry. Proteomics (2004) 1.04
Proteomics in molecular medicine: applications in central nervous systems disorders. Electrophoresis (2000) 1.04
Proteomic analysis of the synaptic plasma membrane fraction isolated from rat forebrain. Brain Res Mol Brain Res (2003) 1.04
The plasma membrane redox system in aging. Ageing Res Rev (2006) 1.03
Impaired mitochondrial respiratory chain and bioenergetics during chagasic cardiomyopathy development. Biochim Biophys Acta (2004) 1.03
High affinity Ca2+-stimulated Mg2+-dependent ATPase in rat brain synaptosomes, synaptic membranes, and microsomes. J Biol Chem (1983) 1.01
The synaptic vesicle proteome. J Neurochem (2007) 1.00
High recovery HPLC separation of lipid rafts for membrane proteome analysis. J Proteome Res (2006) 0.97
Transplasma membrane electron transport: enzymes involved and biological function. Redox Rep (2003) 0.96
Glial responses to steroids as markers of brain aging. J Neurobiol (1999) 0.95
Quantitative proteomics analysis of detergent-resistant membranes from chemical synapses: evidence for cholesterol as spatial organizer of synaptic vesicle cycling. Mol Cell Proteomics (2006) 0.95
The 'lipid raft' microdomain proteins reggie-1 and reggie-2 (flotillins) are scaffolds for protein interaction and signalling. Biochem Soc Symp (2005) 0.94
Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments. Brain Res Bull (2003) 0.93
Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion. J Neurochem (2007) 0.93
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals. J Biol Chem (2004) 0.89
Co-purification and localization of Munc18-1 (p67) and Cdk5 with neuronal cytoskeletal proteins. Neurochem Int (2004) 0.89
Dual role of plasma membrane electron transport systems in defense. Crit Rev Biochem Mol Biol (2000) 0.86
Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia. Dementia (1997) 0.84
Proteomic analysis of the cerebrospinal fluid of patients with schizophrenia. Amino Acids (2003) 0.82
The subcellular localization of glutamate dehydrogenase (GDH): is GDH a marker for mitochondria in brain? Neurochem Res (1986) 0.78
The active zone protein CAST directly associates with Ligand-of-Numb protein X. Biochem Biophys Res Commun (2007) 0.78
Defining lipid raft structure and function with proximity imaging. Am J Physiol Heart Circ Physiol (2006) 0.77
Tubulin and actin mRNAs in the young-adult and the aged rat brain: effects of repeated administration with bifemelane hydrochloride. Arch Gerontol Geriatr (2004) 0.76
IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri. Infect Immun (2006) 2.24
Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine. Hepatology (2010) 2.10
Bile salts stimulate recruitment of IpaB to the Shigella flexneri surface, where it colocalizes with IpaD at the tip of the type III secretion needle. Infect Immun (2007) 1.75
Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes. Proc Natl Acad Sci U S A (2008) 1.71
A three-dimensional molecular model of lipid-free apolipoprotein A-I determined by cross-linking/mass spectrometry and sequence threading. Biochemistry (2005) 1.53
Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo. Chem Res Toxicol (2008) 1.37
Novel regulators of Fgf23 expression and mineralization in Hyp bone. Mol Endocrinol (2009) 1.34
K-Screen: a free application for high throughput screening data analysis, visualization, and laboratory information management. Comb Chem High Throughput Screen (2011) 1.30
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorg Med Chem Lett (2007) 1.27
Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA). Biochem J (2004) 1.10
A three-dimensional homology model of lipid-free apolipoprotein A-IV using cross-linking and mass spectrometry. J Biol Chem (2008) 1.10
Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett (2010) 1.08
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC-electrospray-tandem MS: selective protein oxidation during biological aging. Biochem J (2006) 1.07
Fluorescence labeling, purification, and immobilization of a double cysteine mutant calmodulin fusion protein for single-molecule experiments. Anal Biochem (2004) 1.07
Development of a Grp94 inhibitor. J Am Chem Soc (2012) 1.06
Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line. Bioorg Med Chem (2008) 1.05
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. J Neurosci (2009) 1.04
Hsp90 modulation for the treatment of Alzheimer's disease. Adv Pharmacol (2012) 1.03
Predicting residue-residue contacts using random forest models. Bioinformatics (2011) 1.02
A proteomic analysis of bromobenzene reactive metabolite targets in rat liver cytosol in vivo. Chem Res Toxicol (2007) 1.00
Transcription activation by the DNA-binding domain of the AraC family protein RhaS in the absence of its effector-binding domain. J Bacteriol (2007) 1.00
Direct infusion mass spectrometry of oxylipin-containing Arabidopsis membrane lipids reveals varied patterns in different stress responses. Plant Physiol (2011) 1.00
The reactive metabolite target protein database (TPDB)--a web-accessible resource. BMC Bioinformatics (2007) 0.99
Oxidative inactivation of purified plasma membrane Ca2+-ATPase by hydrogen peroxide and protection by calmodulin. Biochemistry (2003) 0.99
Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. BMC Neurosci (2009) 0.98
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants. BMC Bioinformatics (2010) 0.98
Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons. J Neurochem (2003) 0.98
Sequence-based source tracking of Escherichia coli based on genetic diversity of beta-glucuronidase. J Environ Qual (2004) 0.97
Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Curr Genomics (2010) 0.97
Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins. Brain Res (2003) 0.96
Three-dimensional macroscopic scaffolds with a gradient in stiffness for functional regeneration of interfacial tissues. J Biomed Mater Res A (2010) 0.96
Site-specific arylation of rat glutathione s-transferase A1 and A2 by bromobenzene metabolites in vivo. Chem Res Toxicol (2006) 0.96
Progress in plasmonic engineering of surface-enhanced Raman-scattering substrates toward ultra-trace analysis. Anal Bioanal Chem (2005) 0.95
Age-associated tyrosine nitration of rat skeletal muscle glycogen phosphorylase b: characterization by HPLC-nanoelectrospray-tandem mass spectrometry. Exp Gerontol (2006) 0.95
An automated image-based method for rapid analysis of Chlamydia infection as a tool for screening antichlamydial agents. Antimicrob Agents Chemother (2012) 0.95
Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI. Neuroimage (2011) 0.94
Clearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells. J Mol Neurosci (2009) 0.93
Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion. J Neurochem (2007) 0.93
Decreased activity and increased aggregation of brain calcineurin during aging. Brain Res (2005) 0.92
Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes. Biochemistry (2007) 0.91
RNA--induced silencing of the plasma membrane Ca2+-ATPase 2 in neuronal cells: effects on Ca2+ homeostasis and cell viability. J Neurochem (2007) 0.91
Surface chemistry allows for abiotic precipitation of dolomite at low temperature. Proc Natl Acad Sci U S A (2013) 0.90
PPARβ Regulates Liver Regeneration by Modulating Akt and E2f Signaling. PLoS One (2013) 0.90
Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors. J Mol Neurosci (2003) 0.89
Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. Dev Comp Immunol (2007) 0.89
Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes. Chem Res Toxicol (2012) 0.89
A network-based analysis of polyanion-binding proteins utilizing human protein arrays. J Biol Chem (2007) 0.89
Exome sequencing reveals a thrombopoietin ligand mutation in a Micronesian family with autosomal recessive aplastic anemia. Blood (2013) 0.88
The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling. BMC Genomics (2013) 0.88
Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Hum Vaccin Immunother (2013) 0.88
Progesterone initiates Wnt-beta-catenin signaling but estradiol is required for nuclear activation and synchronous proliferation of rat uterine stromal cells. J Endocrinol (2006) 0.88
Proteomic analysis of protein nitration in rat cerebellum: effect of biological aging. J Neurochem (2007) 0.87
Fluorogenic Tagging of Peptide and Protein 3-Nitrotyrosine with 4-(Aminomethyl)-benzenesulfonic Acid for Quantitative Analysis of Protein Tyrosine Nitration. Chromatographia (2010) 0.87
PROTS: a fragment based protein thermo-stability potential. Proteins (2011) 0.86
Tertiary structural rearrangements upon oxidation of Methionine145 in calmodulin promotes targeted proteasomal degradation. Biophys J (2006) 0.86
beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton. J Mol Neurosci (2006) 0.85
Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. Eur J Pharmacol (2007) 0.85
Novel Algorithms for the Identification of Biologically Informative Chemical Diversity Metrics. Curr Comput Aided Drug Des (2008) 0.85
Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability. Biochemistry (2008) 0.85
Filling and mining the reactive metabolite target protein database. Chem Biol Interact (2008) 0.85
Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca(2+)-ATPase. Free Radic Biol Med (2009) 0.85
Two-dimensional separation of the membrane protein sarcoplasmic reticulum Ca-ATPase for high-performance liquid chromatography-tandem mass spectrometry analysis of posttranslational protein modifications. Anal Biochem (2002) 0.85
Single-molecule dynamics reveal an altered conformation for the autoinhibitory domain of plasma membrane Ca(2+)-ATPase bound to oxidatively modified calmodulin. Biochemistry (2004) 0.84
Isolated RING2 domain of parkin is sufficient for E2-dependent E3 ligase activity. Biochemistry (2013) 0.84
Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells. Biochem Pharmacol (2013) 0.83
A methodology for simultaneous fluorogenic derivatization and boronate affinity enrichment of 3-nitrotyrosine-containing peptides. Anal Biochem (2011) 0.83
A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays. Mol Cell Proteomics (2006) 0.83
Inactivation of rabbit muscle glycogen phosphorylase b by peroxynitrite revisited: does the nitration of Tyr613 in the allosteric inhibition site control enzymatic function? Arch Biochem Biophys (2008) 0.83
Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. PLoS One (2012) 0.83
Activation of brain calcineurin (Cn) by Cu-Zn superoxide dismutase (SOD1) depends on direct SOD1-Cn protein interactions occurring in vitro and in vivo. Biochem J (2007) 0.82
Tracker: continuous HMMER and BLAST searching. Bioinformatics (2004) 0.82
Using multitask classification methods to investigate the kinase-specific phosphorylation sites. Proteome Sci (2012) 0.81
Discrimination of soluble and aggregation-prone proteins based on sequence information. Mol Biosyst (2013) 0.81
PROTS-RF: a robust model for predicting mutation-induced protein stability changes. PLoS One (2012) 0.81
Efficient chemoenzymatic synthesis of globotriose and its derivatives with a recombinant alpha-(1-->4)-galactosyltransferase. Carbohydr Res (2002) 0.80
Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes. Theranostics (2011) 0.80
Theoretically predicted structures of plasma membrane Ca(2+)-ATPase and their susceptibilities to oxidation. J Mol Graph Model (2005) 0.80
Single-molecule dynamics of the calcium-dependent activation of plasma-membrane Ca2+-ATPase by calmodulin. Biophys J (2004) 0.80
Covalent modification of lipids and proteins in rat hepatocytes and in vitro by thioacetamide metabolites. Chem Res Toxicol (2012) 0.80
Single-molecule characterization of the dynamics of calmodulin bound to oxidatively modified plasma-membrane Ca2+-ATPase. Biochemistry (2005) 0.80
Finding minimum gene subsets with heuristic breadth-first search algorithm for robust tumor classification. BMC Bioinformatics (2012) 0.80
Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology. Biochem J (2012) 0.80
Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale. Pharm Res (2013) 0.80
Large-scale Protein-Protein Interaction prediction using novel kernel methods. Int J Data Min Bioinform (2008) 0.80
Fluorescence polarization assay for calmodulin binding to plasma membrane Ca2+-ATPase: dependence on enzyme and Ca2+ concentrations. Anal Biochem (2008) 0.79
Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytes. Chem Res Toxicol (2012) 0.79
Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution. Proteins (2008) 0.79
Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum. ASN Neuro (2011) 0.79
NURBS: a database of experimental and predicted nuclear receptor binding sites of mouse. Bioinformatics (2012) 0.79
I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression. Bioconjug Chem (2012) 0.78
SymDex: increasing the efficiency of chemical fingerprint similarity searches for comparing large chemical libraries by using query set indexing. J Chem Inf Model (2012) 0.78
Decreases in plasma membrane Ca²⁺-ATPase in brain synaptic membrane rafts from aged rats. J Neurochem (2012) 0.78
The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion. Virology (2010) 0.78