Published in Endocr Pract on December 01, 2008
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity (2012) 2.17
Stopping type 1 diabetes: attempts to prevent or cure type 1 diabetes in man. Diabetes (2011) 1.77
Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS One (2010) 1.68
Deal watch: CureDM licenses regenerative diabetes therapy to Sanofi-Aventis. Nat Rev Drug Discov (2010) 1.06
EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. J Exp Med (2017) 0.84
Unraveling pancreatic islet biology by quantitative proteomics. Expert Rev Proteomics (2011) 0.80
Mechanistic evidence in support of alpha1-antitrypsin as a therapeutic approach for type 1 diabetes. J Diabetes Sci Technol (2014) 0.78
Reg3α Overexpression Protects Pancreatic Beta-Cells From Cytokine-Induced Damage and Improves Islet Transplant Outcome. Mol Med (2014) 0.76
Proposal for generating new beta cells in a muted immune environment for type 1 diabetes. Diabetes Metab Res Rev (2013) 0.75
Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PLoS One (2017) 0.75
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res (2007) 2.78
Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system. Cell Metab (2006) 1.76
Insulin independence following isolated islet transplantation and single islet infusions. Ann Surg (2003) 1.67
Replicative senescence: a critical review. Mech Ageing Dev (2004) 1.66
Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. Diabetes (2003) 1.55
GITR Blockade Facilitates Treg Mediated Allograft Survival. Transplantation (2009) 1.48
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer. Cancer Immunol Immunother (2014) 1.39
Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation. J Immunol (2004) 1.34
Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity? Transplantation (2003) 1.32
Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival? Diabetes (2003) 1.27
Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets. Diabetes (2003) 1.25
Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays. Clin Cancer Res (2003) 1.18
A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice. Diabetes (2010) 1.18
Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes (2007) 1.17
Modulation of replicative senescence of diploid human cells by nuclear ERK signaling. J Biol Chem (2006) 1.15
TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance. Eur J Immunol (2014) 1.15
Transplantation for type I diabetes: comparison of vascularized whole-organ pancreas with isolated pancreatic islets. Ann Surg (2004) 1.15
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression. Hum Mol Genet (2008) 1.12
Astrocyte senescence as a component of Alzheimer's disease. PLoS One (2012) 1.11
The use of non-heart-beating donors for isolated pancreatic islet transplantation. Transplantation (2003) 1.03
Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding. Biochemistry (2006) 1.03
Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved. Transpl Int (2004) 0.99
Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell (2013) 0.99
Stress-induced senescence in human and rodent astrocytes. Exp Cell Res (2010) 0.97
Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3{beta} inhibition. J Biol Chem (2010) 0.94
Birth and death of human β-cells in pancreases from cadaver donors, autopsies, surgical specimens, and islets transplanted into mice. Cell Transplant (2013) 0.92
"Zero-length" cross-linking in solid state as an approach for analysis of protein-protein interactions. Protein Sci (2006) 0.91
P62/SQSTM1 at the interface of aging, autophagy, and disease. Age (Dordr) (2014) 0.91
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells. J Immunol (2014) 0.89
Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span. J Gerontol A Biol Sci Med Sci (2013) 0.89
Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells. Diabetes (2006) 0.89
Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance. Transplantation (2008) 0.89
Ampicillin/penicillin-binding protein interactions as a model drug-target system to optimize affinity pull-down and mass spectrometric strategies for target and pathway identification. Proteomics (2005) 0.88
Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease. Mol Pharmacol (2002) 0.88
Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice. Transplantation (2003) 0.88
Transduction of human islets with pseudotyped lentiviral vectors. Hum Gene Ther (2004) 0.88
Serum from aged F344 rats conditions the activation of young macrophages. Mech Ageing Dev (2005) 0.87
Automated purification of recombinant proteins: combining high-throughput with high yield. Protein Expr Purif (2005) 0.86
T-kininogen: a biomarker of aging in Fisher 344 rats with possible implications for the immune response. J Gerontol A Biol Sci Med Sci (2006) 0.84
Long-term IGF-I exposure decreases autophagy and cell viability. PLoS One (2010) 0.84
Association of genetic variants of melatonin receptor 1B with gestational plasma glucose level and risk of glucose intolerance in pregnant Chinese women. PLoS One (2012) 0.84
Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation. Sci Transl Med (2011) 0.84
Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes. J Invest Dermatol (2005) 0.83
B23 is a downstream target of polyamine-modulated CK2. Mol Cell Biochem (2005) 0.82
T-reg mediated suppression of the allograft response in the draining lymph node. Transplantation (2006) 0.81
The select cyclooxygenase-2 inhibitor celecoxib reduced the extent of atherosclerosis in apo E-/- mice. J Surg Res (2007) 0.81
Use of the smart tongue to monitor mold growth and discriminate between four mold species grown in liquid media. Anal Chim Acta (2011) 0.81
The release of sympathetic neurotransmitters is impaired in aged rats after an inflammatory stimulus: a possible link between cytokine production and sympathetic transmission. Mech Ageing Dev (2008) 0.80
Induction of diabetes with signs of autoimmunity in primates by the injection of multiple-low-dose streptozotocin. Biochem Biophys Res Commun (2011) 0.80
The senescence arrest program and the cell cycle. Methods Mol Biol (2014) 0.80
Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival. Eur J Immunol (2010) 0.79
Activation of proteasome by insulin-like growth factor-I may enhance clearance of oxidized proteins in the brain. Mech Ageing Dev (2009) 0.79
α-Cell loss from islet impairs its insulin secretion in vitro and in vivo. Islets (2011) 0.79
Celecoxib combined with atorvastatin prevents progression of atherosclerosis. J Surg Res (2010) 0.79
Avenues for immunomodulation and graft protection by gene therapy in transplantation. Transpl Int (2006) 0.79
Lithium regulates protein tyrosine phosphatase activity in vitro and in vivo. Psychopharmacology (Berl) (2002) 0.79
Personal values and political activism: a cross-national study. Br J Psychol (2014) 0.78
Mechanisms of xenogeneic baboon platelet aggregation and phagocytosis by porcine liver sinusoidal endothelial cells. PLoS One (2012) 0.78
Visualization of single and aggregated hulless oat (Avena nuda L.) (1-->3),(1-->4)-beta-D-glucan molecules by atomic force microscopy and confocal scanning laser microscopy. J Agric Food Chem (2006) 0.78
B-cell depletion improves islet allograft survival with anti-CD45RB. Cell Transplant (2012) 0.78
A direct comparison of rejection by CD8 and CD4 T cells in a transgenic model of allotransplantation. Arch Immunol Ther Exp (Warsz) (2008) 0.78
Detecting senescence: methods and approaches. Methods Mol Biol (2014) 0.78
Progress toward antibody-induced transplantation tolerance. Crit Rev Immunol (2007) 0.77
Availability of suitable islet donors in the United States. Transplantation (2007) 0.77
Defect in ERK2 and p54(JNK) activation in aging mouse splenocytes. J Gerontol A Biol Sci Med Sci (2002) 0.77
Pharmacologically regulated regeneration of functional human pancreatic islets. Mol Ther (2005) 0.76
Statistically inferring protein-protein associations with affinity isolation LC-MS/MS assays. J Proteome Res (2007) 0.76
Specific in situ detection of murine indoleamine 2, 3-dioxygenase. J Cell Biochem (2014) 0.76
An immunosufficient murine model for the study of human islets. Xenotransplantation (2014) 0.76
Distribution of different taste buds and expression of alpha-gustducin in the barbells of yellow catfish (Pelteobagrus fulvidraco). Fish Physiol Biochem (2006) 0.76
Elevated levels of interferon-γ production by memory T cells do not promote transplant tolerance resistance in aged recipients. PLoS One (2013) 0.75
Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols. Transplantation (2011) 0.75
Monitoring of Allogeneic Islet Grafts in Nonhuman Primates Using MRI. Transplantation (2015) 0.75
Familial multinodular goiter syndrome with papillary thyroid carcinomas: mutational analysis of the associated genes in 5 cases from 1 Chinese family. BMC Endocr Disord (2013) 0.75
Relationship of spindle assembly checkpoint fidelity to species body mass, lifespan, and developmental rate. Aging (Albany NY) (2011) 0.75
Simple protein complex purification and identification method for high-throughput mapping of protein interaction networks. J Proteome Res (2005) 0.75
[Autologous peripheral blood CD34+ stem cells transplanted into 100 patients with advanced cirrhosis]. Zhonghua Gan Zang Bing Za Zhi (2014) 0.75
High-throughput protein concentration and buffer exchange: comparison of ultrafiltration and ammonium sulfate precipitation. Methods Mol Biol (2009) 0.75
[Detection of pathogenic Vibrio by smartongue]. Wei Sheng Wu Xue Bao (2010) 0.75
Automated 96-well purification of hexahistidine-tagged recombinant proteins on MagneHis Ni(2)+-particles. Methods Mol Biol (2009) 0.75
[National and regional distribution of hepatitis C virus genotypes in Chile]. Rev Chilena Infectol (2013) 0.75