Published in Biochemistry on February 17, 2009
Orchestrating redox signaling networks through regulatory cysteine switches. ACS Chem Biol (2010) 2.87
Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity. Nat Chem Biol (2011) 2.03
Cysteine-based redox switches in enzymes. Antioxid Redox Signal (2010) 1.62
Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation. Biochemistry (2012) 1.35
Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome". Cell (2011) 1.34
The redox biochemistry of protein sulfenylation and sulfinylation. J Biol Chem (2013) 1.30
Regulation of signal transduction by reactive oxygen species in the cardiovascular system. Circ Res (2015) 1.27
Sulfenic acid chemistry, detection and cellular lifetime. Biochim Biophys Acta (2013) 1.23
Redox signaling in cardiovascular health and disease. Free Radic Biol Med (2013) 1.16
Picomolar concentrations of free zinc(II) ions regulate receptor protein-tyrosine phosphatase β activity. J Biol Chem (2012) 1.12
Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies. Antioxid Redox Signal (2011) 0.97
The biological buffer bicarbonate/CO2 potentiates H2O2-mediated inactivation of protein tyrosine phosphatases. J Am Chem Soc (2011) 0.95
Identification of in vivo disulfide conformation of TRPA1 ion channel. J Biol Chem (2011) 0.95
Protection of a single-cysteine redox switch from oxidative destruction: On the functional role of sulfenyl amide formation in the redox-regulated enzyme PTP1B. Bioorg Med Chem Lett (2009) 0.93
Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease. Biochemistry (2012) 0.92
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling. Proc Natl Acad Sci U S A (2013) 0.91
Reactivation of oxidized PTP1B and PTEN by thioredoxin 1. FEBS J (2014) 0.90
Methods to monitor classical protein-tyrosine phosphatase oxidation. FEBS J (2012) 0.90
Thiol-dependent recovery of catalytic activity from oxidized protein tyrosine phosphatases. Biochemistry (2013) 0.87
Structure analysis of the Staphylococcus aureus UDP-N-acetyl-mannosamine dehydrogenase Cap5O involved in capsular polysaccharide biosynthesis. J Biol Chem (2011) 0.86
Targeting the redox balance in inflammatory skin conditions. Int J Mol Sci (2013) 0.84
THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1. Nat Immunol (2017) 0.84
Targeting a cryptic allosteric site for selective inhibition of the oncogenic protein tyrosine phosphatase Shp2. Biochemistry (2015) 0.84
Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1. J Clin Invest (2014) 0.82
Estimation of kinetic parameters related to biochemical interactions between hydrogen peroxide and signal transduction proteins. Front Chem (2014) 0.81
Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Radic Biol Med (2014) 0.81
The chemical biology of protein hydropersulfides: Studies of a possible protective function of biological hydropersulfide generation. Free Radic Biol Med (2016) 0.78
Reactive oxygen species and epidermal growth factor are antagonistic cues controlling SHP-2 dimerization. Mol Cell Biol (2012) 0.78
Biological chemistry and functionality of protein sulfenic acids and related thiol modifications. Free Radic Res (2015) 0.77
Protein topology determines cysteine oxidation fate: the case of sulfenyl amide formation among protein families. PLoS Comput Biol (2015) 0.77
Rational design of allosteric-inhibition sites in classical protein tyrosine phosphatases. Bioorg Med Chem (2015) 0.77
Dynamic Redox Regulation of IL-4 Signaling. PLoS Comput Biol (2015) 0.77
An immunochemical approach to detect oxidized protein tyrosine phosphatases using a selective C-nucleophile tag. Mol Biosyst (2016) 0.76
New and Unexpected Biological Functions for the Src-Homology 2 Domain-Containing Phosphatase SHP-2 in the Gastrointestinal Tract. Cell Mol Gastroenterol Hepatol (2015) 0.76
ATP and Mg2+ promote the reversible oligomerization and aggregation of chloroplast 2-Cys peroxiredoxin. J Biol Chem (2011) 0.75
Cellular biochemistry methods for investigating protein tyrosine phosphatases. Antioxid Redox Signal (2014) 0.75
Redox regulation of cGMP-dependent protein kinase Iα in the cardiovascular system. Front Pharmacol (2015) 0.75
Inactivation of protein tyrosine phosphatases by oltipraz and other cancer chemopreventive 1,2-dithiole-3-thiones. Bioorg Med Chem (2010) 0.75
Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration. Sci Rep (2017) 0.75
A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin. Biochemistry (2005) 1.86
Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design. Biochemistry (2005) 1.40
Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction. Biochemistry (2003) 1.38
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. Biochemistry (2005) 1.21
Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation. Curr Biol (2007) 1.14
Redox regulation of MAP kinase phosphatase 3. Biochemistry (2006) 1.09
Protein-protein interfaces: properties, preferences, and projections. J Proteome Res (2007) 1.08
Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond. Biochemistry (2005) 1.03
Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate. Biochemistry (2005) 1.03
Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines. Biochemistry (2004) 0.97
Mechanism of Cdc25B phosphatase with the small molecule substrate p-nitrophenyl phosphate from QM/MM-MFEP calculations. J Phys Chem B (2009) 0.96
Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J Med Chem (2003) 0.91
Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase. Biochemistry (2007) 0.86
The energetic network of hotspot residues between Cdc25B phosphatase and its protein substrate. J Mol Biol (2006) 0.85
Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol. Proc Natl Acad Sci U S A (2013) 0.83
Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum. Biochemistry (2012) 0.83
Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules. Biochemistry (2007) 0.83
A fluorescence polarization assay for native protein substrates of kinases. Anal Biochem (2003) 0.81
Temperature dependence of binding and catalysis for the Cdc25B phosphatase. Biophys Chem (2006) 0.81
Redox control of cell cycle progression via Cdc25 phosphatase (Mih1p) in S. cerevisiae. Cell Cycle (2006) 0.77
Evaluating the quality of NMR structures by local density of protons. Proteins (2006) 0.76
Parallel effects of genetic variation in ACE activity in baboons and humans. Am J Phys Anthropol (2007) 0.75
Facile variation of reagent concentrations in rapid quench enzymology. Anal Biochem (2003) 0.75
Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1. Cell Cycle (2006) 0.75