Published in Cell Cycle on February 06, 2009
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Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev (2009) 2.40
Complexity of the microRNA repertoire revealed by next-generation sequencing. RNA (2010) 2.38
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation. EMBO J (2010) 1.77
Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells. Cell Cycle (2010) 1.71
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. Cell Death Differ (2011) 1.44
Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. PLoS One (2011) 1.34
Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene. Cancer (2010) 1.34
Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.19
The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1. RNA (2012) 1.18
Reviewing and updating the major molecular markers for stem cells. Stem Cells Dev (2013) 1.11
MicroRNA biogenesis and regulation of bone remodeling. Arthritis Res Ther (2011) 1.11
The abbreviated pluripotent cell cycle. J Cell Physiol (2013) 1.09
Rapid neurogenesis through transcriptional activation in human stem cells. Mol Syst Biol (2014) 1.05
miRNA profiles as a predictor of chemoresponsiveness in Wilms' tumor blastema. PLoS One (2013) 1.02
Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway. J Biol Chem (2012) 0.96
NMDA mediated contextual conditioning changes miRNA expression. PLoS One (2011) 0.96
MicroRNAs in human embryonic and cancer stem cells. Yonsei Med J (2010) 0.93
Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells. PLoS One (2012) 0.93
Concise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion. Stem Cells (2014) 0.91
Transient in vitro epigenetic reprogramming of skin fibroblasts into multipotent cells. Biomaterials (2009) 0.90
ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner. Cell Res (2015) 0.87
Epigenetic landscape of pluripotent stem cells. Antioxid Redox Signal (2012) 0.86
Pluripotent stem cell miRNAs and metastasis in invasive breast cancer. J Natl Cancer Inst (2014) 0.86
How microRNAs facilitate reprogramming to pluripotency. J Cell Sci (2012) 0.85
Down-regulation of miR-302b, an ESC-specific microRNA, in Gastric Adenocarcinoma. Cell J (2011) 0.85
The Wnt/β-catenin pathway regulates the expression of the miR-302 cluster in mouse ESCs and P19 cells. PLoS One (2013) 0.85
Cell-specific detection of microRNA expression during cardiomyogenesis by combined in situ hybridization and immunohistochemistry. J Mol Histol (2011) 0.83
Enrichment of A Rare Subpopulation of miR-302-Expressing Glioma Cells by Serum Deprivation. Cell J (2015) 0.82
miRNA in pluripotent stem cells. Regen Med (2010) 0.82
MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells. Sci Rep (2016) 0.80
Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression. Breast Cancer Res Treat (2014) 0.80
The miR-302/367 cluster: a comprehensive update on its evolution and functions. Open Biol (2015) 0.80
High miR-196a and low miR-367 cooperatively correlate with unfavorable prognosis of high-grade glioma. Int J Clin Exp Pathol (2015) 0.80
Accurate primary germ cell cancer diagnosis using serum based microRNA detection (ampTSmiR test). Oncotarget (2016) 0.78
Characterization of embryonic stem-like cells derived from HEK293T cells through miR302/367 expression and their potentiality to differentiate into germ-like cells. Cytotechnology (2013) 0.78
Dissecting microRNA-mediated regulation of stemness, reprogramming, and pluripotency. Cell Regen (Lond) (2016) 0.78
MicroRNA-302b Enhances the Sensitivity of Hepatocellular Carcinoma Cell Lines to 5-FU via Targeting Mcl-1 and DPYD. Int J Mol Sci (2015) 0.77
Embryonal carcinoma cell induction of miRNA and mRNA changes in co-cultured prostate stromal fibromuscular cells. J Cell Physiol (2011) 0.77
Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. Int J Oncol (2015) 0.77
MiR-302a inhibits the tumorigenicity of ovarian cancer cells by suppression of SDC1. Int J Clin Exp Pathol (2015) 0.76
MicroRNAs in regulation of pluripotency and somatic cell reprogramming: small molecule with big impact. RNA Biol (2013) 0.76
Cellular Reprogramming Using Defined Factors and MicroRNAs. Stem Cells Int (2016) 0.75
Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types. Nucleic Acids Res (2017) 0.75
Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth. Cell Death Dis (2017) 0.75
RNA mimics as therapeutics for cardiac regeneration: a paradigm shift. Mol Ther (2015) 0.75
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature (2007) 3.74
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med (2005) 2.42
Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nat Methods (2006) 2.31
Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter. Mol Cell Biol (2008) 1.74
Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation. Cytotherapy (2010) 1.64
Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties? Mol Cancer (2008) 1.55
FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs. Blood (2013) 1.55
A promoter DNA demethylation landscape of human hematopoietic differentiation. Nucleic Acids Res (2011) 1.49
Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood (2005) 1.49
Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells. Nature (2010) 1.47
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells (2010) 1.36
Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease. Stem Cells (2011) 1.27
The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells. FASEB J (2011) 1.27
OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells. Stem Cells (2008) 1.24
Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells. Carcinogenesis (2009) 1.23
Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-beta and IGF-II. Cell Res (2009) 1.14
Epigenetic control of retrotransposon expression in human embryonic stem cells. Mol Cell Biol (2010) 1.14
Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo. Cancer Res (2010) 1.13
Cancer genes hypermethylated in human embryonic stem cells. PLoS One (2008) 1.12
Hematopoietic development from human embryonic stem cell lines. Exp Hematol (2005) 1.11
SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells. Mol Ther (2012) 1.09
Nodal/Activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage. Mol Ther (2010) 1.09
Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells. Neoplasia (2009) 1.09
Modeling sarcomagenesis using multipotent mesenchymal stem cells. Cell Res (2011) 1.09
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors. PLoS One (2012) 1.08
FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells. Stem Cells (2011) 1.07
iPSCs from cancer cells: challenges and opportunities. Trends Mol Med (2012) 1.04
Maintenance of human embryonic stem cells in mesenchymal stem cell-conditioned media augments hematopoietic specification. Stem Cells Dev (2011) 1.00
Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells. Hum Mol Genet (2011) 0.99
The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs. Stem Cell Rev (2010) 0.98
Conventional and molecular cytogenetic diagnostic methods in stem cell research: a concise review. Cell Biol Int (2007) 0.98
The adaptation of human embryonic stem cells to different feeder-free culture conditions is accompanied by a mitochondrial response. Stem Cells Dev (2011) 0.97
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification. Cell Res (2012) 0.95
iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability. Cell Res (2010) 0.93
Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation. Stem Cells (2013) 0.91
Concise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion. Stem Cells (2014) 0.91
Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic repopulating stem cell function. Haematologica (2013) 0.90
Maintenance of human embryonic stem cells in media conditioned by human mesenchymal stem cells obviates the requirement of exogenous basic fibroblast growth factor supplementation. Tissue Eng Part C Methods (2012) 0.90
Endoplasmic reticulum stress signals in defined human embryonic stem cell lines and culture conditions. Stem Cell Rev (2010) 0.87
Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human embryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbiological quality assurance program in stem cell banks. Cloning Stem Cells (2008) 0.87
Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice. Exp Hematol (2005) 0.84
Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells. Stem Cells (2014) 0.84
Bone microenvironment signals in osteosarcoma development. Cell Mol Life Sci (2015) 0.83
Molecular profiling of candidate human hematopoietic stem cells derived from human embryonic stem cells. Exp Hematol (2008) 0.83
Derivation and characterization of hematopoietic cells from human embryonic stem cells. Methods Mol Biol (2006) 0.83
Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors. PLoS One (2012) 0.82
The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo. Stem Cells Dev (2013) 0.81
Purification and long-term expansion of multipotent endothelial-like cells with potential cardiovascular regeneration. Stem Cells Dev (2011) 0.80
Concise review: induced pluripotency by defined factors: prey of oxidative stress. Stem Cells (2015) 0.80
Intrahepatic transplantation of cord blood CD34+ cells into newborn NOD/SCID-IL2Rγ(null) mice allows efficient multi-organ and multi-lineage hematopoietic engraftment without accessory cells. Clin Immunol (2012) 0.78
Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells. PLoS One (2012) 0.78
Bone marrow stromal cell-derived Wnt signals as a potential underlying mechanism for cyclin D1 deregulation in multiple myeloma lacking t(11;14)(q13;q32). Blood Cells Mol Dis (2007) 0.78
Spanish stem cell bank interviews examine the interest of couples in donating surplus human IVF embryos for stem cell research. Cell Stem Cell (2007) 0.77
Expression of NG2 antigen in MLL-rearranged acute leukemias: how complex does it get? Leuk Res (2011) 0.76
Toward development of a novel NOD/SCID-based in vivo strategy to model multiple myeloma pathogenesis. Exp Hematol (2007) 0.75
Analysis of mRNA abundance and stability by ribonuclease protection assay. Methods Mol Biol (2012) 0.75
Evaluation of a laser technique to isolate the inner cell mass of murine blastocysts. Biotechnol Appl Biochem (2007) 0.75
Reproductive medicine meets human embryonic stem cell (hESC) research: the need to adjust the regulatory framework to actual expectations and potential detrimental consequences of hESC research. Fertil Steril (2008) 0.75
Making business out of patients? Blood (2008) 0.75