Published in Carcinogenesis on July 08, 2009
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Res (2011) 2.85
Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis. Mol Cell (2012) 1.46
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells (2010) 1.36
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. Nat Biotechnol (2013) 1.36
Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene. J Exp Med (2009) 1.31
SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells. Mol Ther (2012) 1.09
Nodal/Activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage. Mol Ther (2010) 1.09
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors. PLoS One (2012) 1.08
Secondary leukemia associated with the anti-cancer agent, etoposide, a topoisomerase II inhibitor. Int J Environ Res Public Health (2012) 0.96
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification. Cell Res (2012) 0.95
Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanism. Front Cell Dev Biol (2015) 0.90
Apoptotic susceptibility to DNA damage of pluripotent stem cells facilitates pharmacologic purging of teratoma risk. Stem Cells Transl Med (2012) 0.90
Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic repopulating stem cell function. Haematologica (2013) 0.90
A novel topoisomerase inhibitor, daurinol, suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide. Neoplasia (2011) 0.88
Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia. Blood (2015) 0.88
MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. Cell Cycle (2014) 0.83
Ligand-independent FLT3 activation does not cooperate with MLL-AF4 to immortalize/transform cord blood CD34+ cells. Leukemia (2013) 0.82
Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease. Haematologica (2014) 0.81
Role of BRD4 in hematopoietic differentiation of embryonic stem cells. Epigenetics (2014) 0.79
Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency. Stem Cell Reports (2016) 0.79
Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair. Oncotarget (2016) 0.77
Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms. Int J Mol Sci (2016) 0.77
Changes in human pluripotent stem cell gene expression after genotoxic stress exposures. World J Stem Cells (2014) 0.77
Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells. PLoS One (2015) 0.77
Incidence of common preleukemic gene fusions in umbilical cord blood in Slovak population. PLoS One (2014) 0.76
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature (2007) 3.74
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med (2005) 2.42
Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nat Methods (2006) 2.31
Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter. Mol Cell Biol (2008) 1.74
The miR-302-367 cluster as a potential stemness regulator in ESCs. Cell Cycle (2009) 1.68
Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation. Cytotherapy (2010) 1.64
Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties? Mol Cancer (2008) 1.55
FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs. Blood (2013) 1.55
A promoter DNA demethylation landscape of human hematopoietic differentiation. Nucleic Acids Res (2011) 1.49
Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood (2005) 1.49
Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells. Nature (2010) 1.47
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells (2010) 1.36
Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene. J Exp Med (2009) 1.31
Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease. Stem Cells (2011) 1.27
The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells. FASEB J (2011) 1.27
OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells. Stem Cells (2008) 1.24
Susceptibility of different leukocyte cell types to Vaccinia virus infection. Virol J (2004) 1.21
Microbiological control in stem cell banks: approaches to standardisation. Appl Microbiol Biotechnol (2005) 1.14
Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-beta and IGF-II. Cell Res (2009) 1.14
Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo. Cancer Res (2010) 1.13
Cancer genes hypermethylated in human embryonic stem cells. PLoS One (2008) 1.12
Hematopoietic development from human embryonic stem cell lines. Exp Hematol (2005) 1.11
SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells. Mol Ther (2012) 1.09
Nodal/Activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage. Mol Ther (2010) 1.09
Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells. Neoplasia (2009) 1.09
Modeling sarcomagenesis using multipotent mesenchymal stem cells. Cell Res (2011) 1.09
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors. PLoS One (2012) 1.08
A microsatellite genetic map of the turbot (Scophthalmus maximus). Genetics (2007) 1.07
FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells. Stem Cells (2011) 1.07
Identification of the major sex-determining region of turbot (Scophthalmus maximus). Genetics (2009) 1.05
iPSCs from cancer cells: challenges and opportunities. Trends Mol Med (2012) 1.04
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer. Mol Cancer (2010) 1.02
Maintenance of human embryonic stem cells in mesenchymal stem cell-conditioned media augments hematopoietic specification. Stem Cells Dev (2011) 1.00
Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells. Hum Mol Genet (2011) 0.99
The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs. Stem Cell Rev (2010) 0.98
Conventional and molecular cytogenetic diagnostic methods in stem cell research: a concise review. Cell Biol Int (2007) 0.98
The adaptation of human embryonic stem cells to different feeder-free culture conditions is accompanied by a mitochondrial response. Stem Cells Dev (2011) 0.97
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification. Cell Res (2012) 0.95
Analysis of qPCR reference gene stability determination methods and a practical approach for efficiency calculation on a turbot (Scophthalmus maximus) gonad dataset. BMC Genomics (2014) 0.94
iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability. Cell Res (2010) 0.93
Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation. Stem Cells (2013) 0.91
Concise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion. Stem Cells (2014) 0.91
Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic repopulating stem cell function. Haematologica (2013) 0.90
Maintenance of human embryonic stem cells in media conditioned by human mesenchymal stem cells obviates the requirement of exogenous basic fibroblast growth factor supplementation. Tissue Eng Part C Methods (2012) 0.90
Clinical and immunological features of adult-onset generalized autoimmune gut disorder. Am J Gastroenterol (2004) 0.89
Endoplasmic reticulum stress signals in defined human embryonic stem cell lines and culture conditions. Stem Cell Rev (2010) 0.87
Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human embryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbiological quality assurance program in stem cell banks. Cloning Stem Cells (2008) 0.87
Cytokine production by intestinal intraepithelial lymphocyte subsets in celiac disease. Dig Dis Sci (2005) 0.85
Immune response towards snake venoms. Inflamm Allergy Drug Targets (2011) 0.85
Diversity in isochore structure among cold-blooded vertebrates based on GC content of coding and non-coding sequences. Genetica (2006) 0.85
Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells. Stem Cells (2014) 0.84
Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice. Exp Hematol (2005) 0.84
Bone microenvironment signals in osteosarcoma development. Cell Mol Life Sci (2015) 0.83
Derivation and characterization of hematopoietic cells from human embryonic stem cells. Methods Mol Biol (2006) 0.83
Molecular profiling of candidate human hematopoietic stem cells derived from human embryonic stem cells. Exp Hematol (2008) 0.83
Modulation of peripheral μ-opioid analgesia by σ1 receptors. J Pharmacol Exp Ther (2013) 0.82
Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors. PLoS One (2012) 0.82
The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo. Stem Cells Dev (2013) 0.81
Purification and long-term expansion of multipotent endothelial-like cells with potential cardiovascular regeneration. Stem Cells Dev (2011) 0.80
Concise review: induced pluripotency by defined factors: prey of oxidative stress. Stem Cells (2015) 0.80
A sex-associated sequence identified by RAPD screening in gynogenetic individuals of turbot (Scophthalmus maximus). Mol Biol Rep (2014) 0.79
Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells. PLoS One (2012) 0.78
Intrahepatic transplantation of cord blood CD34+ cells into newborn NOD/SCID-IL2Rγ(null) mice allows efficient multi-organ and multi-lineage hematopoietic engraftment without accessory cells. Clin Immunol (2012) 0.78
Bone marrow stromal cell-derived Wnt signals as a potential underlying mechanism for cyclin D1 deregulation in multiple myeloma lacking t(11;14)(q13;q32). Blood Cells Mol Dis (2007) 0.78
Recombination analysis of the human minisatellite MsH42 suggests the existence of two distinct pathways for initiation and resolution of recombination at MsH42 in rat testes nuclear extracts. Biochemistry (2002) 0.78