Published in Anal Chem on March 15, 2009
Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures. Acc Chem Res (2010) 1.75
CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications. PLoS One (2011) 1.32
DNA electrochemistry with tethered methylene blue. Langmuir (2012) 1.07
Using triplex-forming oligonucleotide probes for the reagentless, electrochemical detection of double-stranded DNA. Anal Chem (2010) 1.01
Electrochemical sensors. Anal Chem (2010) 0.99
Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor. J Am Chem Soc (2012) 0.99
Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors. Anal Chem (2010) 0.92
DNA diagnostics: nanotechnology-enhanced electrochemical detection of nucleic acids. Pediatr Res (2010) 0.92
Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences. Anal Chem (2011) 0.88
Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice. Appl Environ Microbiol (2013) 0.82
Fabrication of electrochemical-DNA biosensors for the reagentless detection of nucleic acids, proteins and small molecules. J Vis Exp (2011) 0.82
Reagentless, ratiometric electrochemical DNA sensors with improved robustness and reproducibility. Anal Chem (2014) 0.81
Hybridization kinetics between immobilized double-stranded DNA probes and targets containing embedded recognition segments. Nucleic Acids Res (2011) 0.78
Hybridization efficiency of molecular beacons bound to gold nanowires: effect of surface coverage and target length. Langmuir (2010) 0.77
A sandwich-type DNA electrochemical biosensor for hairpin-stem-loop structure based on multistep temperature-controlling method. Int J Nanomedicine (2012) 0.75
Random-coil behavior and the dimensions of chemically unfolded proteins. Proc Natl Acad Sci U S A (2004) 4.44
Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA. Proc Natl Acad Sci U S A (2003) 2.95
Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor. Angew Chem Int Ed Engl (2005) 2.47
An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids. J Am Chem Soc (2006) 2.40
Contact order revisited: influence of protein size on the folding rate. Protein Sci (2003) 2.37
Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing. Nat Protoc (2007) 2.04
Toward a taxonomy of the denatured state: small angle scattering studies of unfolded proteins. Adv Protein Chem (2002) 2.02
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci (2005) 1.91
Effect of molecular crowding on the response of an electrochemical DNA sensor. Langmuir (2007) 1.87
Electrochemical detection of parts-per-billion lead via an electrode-bound DNAzyme assembly. J Am Chem Soc (2007) 1.85
Real-time, aptamer-based tracking of circulating therapeutic agents in living animals. Sci Transl Med (2013) 1.79
Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures. Acc Chem Res (2010) 1.75
A reagentless signal-on architecture for electronic, aptamer-based sensors via target-induced strand displacement. J Am Chem Soc (2005) 1.73
Sequence-specific, electronic detection of oligonucleotides in blood, soil, and foodstuffs with the reagentless, reusable E-DNA sensor. Anal Chem (2006) 1.66
Beyond superquenching: hyper-efficient energy transfer from conjugated polymers to gold nanoparticles. Proc Natl Acad Sci U S A (2003) 1.64
Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor. J Am Chem Soc (2009) 1.63
Aptamer-based electrochemical detection of picomolar platelet-derived growth factor directly in blood serum. Anal Chem (2007) 1.59
Bench-top method for fabricating glass-sealed nanodisk electrodes, glass nanopore electrodes, and glass nanopore membranes of controlled size. Anal Chem (2007) 1.49
Is there or isn't there? The case for (and against) residual structure in chemically denatured proteins. Crit Rev Biochem Mol Biol (2005) 1.47
Structure-switching biosensors: inspired by Nature. Curr Opin Struct Biol (2010) 1.40
Optimization of electrochemical aptamer-based sensors via optimization of probe packing density and surface chemistry. Langmuir (2008) 1.40
Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors. Proc Natl Acad Sci U S A (2009) 1.40
How the folding rate constant of simple, single-domain proteins depends on the number of native contacts. Proc Natl Acad Sci U S A (2002) 1.38
High specificity, electrochemical sandwich assays based on single aptamer sequences and suitable for the direct detection of small-molecule targets in blood and other complex matrices. J Am Chem Soc (2009) 1.38
The topomer search model: A simple, quantitative theory of two-state protein folding kinetics. Protein Sci (2003) 1.37
Linear, redox modified DNA probes as electrochemical DNA sensors. Chem Commun (Camb) (2007) 1.37
Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms. J Biol Chem (2010) 1.36
CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications. PLoS One (2011) 1.32
Biosensors based on binding-modulated donor-acceptor distances. Trends Biotechnol (2005) 1.29
Engineering a signal transduction mechanism for protein-based biosensors. Proc Natl Acad Sci U S A (2005) 1.29
Single-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplex. Proc Natl Acad Sci U S A (2006) 1.27
Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes. Proc Natl Acad Sci U S A (2010) 1.27
Site-specific dimensions across a highly denatured protein; a single molecule study. J Mol Biol (2005) 1.25
An electrochemical sensor for the detection of protein-small molecule interactions directly in serum and other complex matrices. J Am Chem Soc (2009) 1.25
Comparison of the signaling and stability of electrochemical DNA sensors fabricated from 6- or 11-carbon self-assembled monolayers. Langmuir (2006) 1.18
Label-free electrochemical detection of DNA in blood serum via target-induced resolution of an electrode-bound DNA pseudoknot. J Am Chem Soc (2007) 1.17
Rapid, sequence-specific detection of unpurified PCR amplicons via a reusable, electrochemical sensor. Proc Natl Acad Sci U S A (2006) 1.16
Using protein folding rates to test protein folding theories. Annu Rev Biochem (2004) 1.12
Microfluidic device architecture for electrochemical patterning and detection of multiple DNA sequences. Langmuir (2008) 1.09
Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins. Anal Chem (2009) 1.08
High-efficiency fluorescence quenching of conjugated polymers by proteins. J Am Chem Soc (2002) 1.07
Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy. Protein Sci (2006) 1.06
On the precision of experimentally determined protein folding rates and phi-values. Protein Sci (2006) 1.06
The protein folding transition state: what are Phi-values really telling us? Protein Pept Lett (2005) 1.05
Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range. J Am Chem Soc (2012) 1.04
Improving the stability and sensing of electrochemical biosensors by employing trithiol-anchoring groups in a six-carbon self-assembled monolayer. Anal Chem (2009) 1.04
Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe. Angew Chem Int Ed Engl (2009) 1.04
Absorption spectra of liquid water and aqueous buffers between 0.3 and 3.72 THz. J Chem Phys (2006) 1.04
Reagentless measurement of aminoglycoside antibiotics in blood serum via an electrochemical, ribonucleic acid aptamer-based biosensor. Anal Chem (2010) 1.03
Optimization of a reusable, DNA pseudoknot-based electrochemical sensor for sequence-specific DNA detection in blood serum. Anal Chem (2009) 1.03
Residues participating in the protein folding nucleus do not exhibit preferential evolutionary conservation. J Mol Biol (2002) 1.02
Excimer-based peptide beacons: a convenient experimental approach for monitoring polypeptide-protein and polypeptide-oligonucleotide interactions. J Am Chem Soc (2006) 1.01
Using triplex-forming oligonucleotide probes for the reagentless, electrochemical detection of double-stranded DNA. Anal Chem (2010) 1.01
Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors. J Am Chem Soc (2012) 1.01
Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor. J Am Chem Soc (2012) 0.99
Rapid, sensitive, and quantitative detection of pathogenic DNA at the point of care through microfluidic electrochemical quantitative loop-mediated isothermal amplification. Angew Chem Int Ed Engl (2012) 0.99
On the Signaling of Electrochemical Aptamer-Based Sensors: Collision- and Folding-Based Mechanisms. Electroanalysis (2009) 0.99
Sensitivity and signal complexity as a function of the number of ion channels in a stochastic sensor. Anal Chem (2009) 0.99
Cooperativity, smooth energy landscapes and the origins of topology-dependent protein folding rates. J Mol Biol (2003) 0.98
Equilibrium collapse and the kinetic 'foldability' of proteins. Biochemistry (2002) 0.97
The backbone conformational entropy of protein folding: experimental measures from atomic force microscopy. J Mol Biol (2002) 0.97
Comparing the properties of electrochemical-based DNA sensors employing different redox tags. Anal Chem (2009) 0.96
Sensitive and selective amplified fluorescence DNA detection based on exonuclease III-aided target recycling. J Am Chem Soc (2010) 0.96
Differential labeling of closely spaced biosensor electrodes via electrochemical lithography. Langmuir (2006) 0.96
Influence of local and residual structures on the scaling behavior and dimensions of unfolded proteins. Biopolymers (2007) 0.96
Apparent Debye-Huckel electrostatic effects in the folding of a simple, single domain protein. Biochemistry (2005) 0.96
Peptide beacons: a new design for polypeptide-based optical biosensors. Bioconjug Chem (2007) 0.96
An electrochemical supersandwich assay for sensitive and selective DNA detection in complex matrices. J Am Chem Soc (2010) 0.96
Cooperativity and the origins of rapid, single-exponential kinetics in protein folding. Protein Sci (2006) 0.95
High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks. PLoS Comput Biol (2011) 0.95
Re-engineering aptamers to support reagentless, self-reporting electrochemical sensors. Analyst (2010) 0.94
Surface chemistry effects on the performance of an electrochemical DNA sensor. Bioelectrochemistry (2009) 0.94
Achieving reproducible performance of electrochemical, folding aptamer-based sensors on microelectrodes: challenges and prospects. Anal Chem (2014) 0.94
The length and viscosity dependence of end-to-end collision rates in single-stranded DNA. Biophys J (2009) 0.93
Beyond molecular beacons: optical sensors based on the binding-induced folding of proteins and polypeptides. Chemistry (2009) 0.93
NMR and temperature-jump measurements of de novo designed proteins demonstrate rapid folding in the absence of explicit selection for kinetics. J Mol Biol (2003) 0.93
Glass nanopore-based ion-selective electrodes. Anal Chem (2007) 0.92
Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors. Anal Chem (2010) 0.92
Measuring distances within unfolded biopolymers using fluorescence resonance energy transfer: The effect of polymer chain dynamics on the observed fluorescence resonance energy transfer efficiency. J Chem Phys (2009) 0.92
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. J Mol Biol (2003) 0.91
Simultaneous alternating and direct current readout of protein ion channel blocking events using glass nanopore membranes. Anal Chem (2008) 0.91
Transcription factor beacons for the quantitative detection of DNA binding activity. J Am Chem Soc (2011) 0.90
A mechanistic study of electron transfer from the distal termini of electrode-bound, single-stranded DNAs. J Am Chem Soc (2010) 0.90
Methods for the accurate estimation of confidence intervals on protein folding phi-values. Protein Sci (2006) 0.90
Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range. Angew Chem Int Ed Engl (2012) 0.89
Experimental investigation of the frequency and substitution dependence of negative phi-values in two-state proteins. Biochemistry (2005) 0.89
An electrochemical sensor for single nucleotide polymorphism detection in serum based on a triple-stem DNA probe. J Am Chem Soc (2009) 0.89
Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences. Anal Chem (2011) 0.88
On the binding of cationic, water-soluble conjugated polymers to DNA: electrostatic and hydrophobic interactions. J Am Chem Soc (2010) 0.87