Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: a randomized trial.

PubWeight™: 4.11‹?› | Rank: Top 1%

🔗 View Article (PMID 19221370)

Published in Ann Intern Med on February 16, 2009

Authors

Joseph J Y Sung1, Alan Barkun, Ernst J Kuipers, Joachim Mössner, Dennis M Jensen, Robert Stuart, James Y Lau, Henrik Ahlbom, Jan Kilhamn, Tore Lind, Peptic Ulcer Bleed Study Group

Author Affiliations

1: Institute of Digestive Diseases, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China. joesung@cuhk.edu.hk

Associated clinical trials:

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer | NCT00251979

Esomeprazole Versus Pantoprazole to Prevent Peptic Ulcer Rebleeding | NCT00881413

Oral Omeprazole in Bleeding Peptic Ulcer | NCT04170270

Articles citing this

Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointest Endosc (2015) 1.60

The Indications, Applications, and Risks of Proton Pump Inhibitors. Dtsch Arztebl Int (2016) 1.45

Management of acute nonvariceal upper gastrointestinal bleeding: current policies and future perspectives. World J Gastroenterol (2012) 1.09

Diagnosis and management of nonvariceal upper gastrointestinal bleeding. Nat Rev Gastroenterol Hepatol (2012) 1.06

Clinical outcomes and risk factors of rebleeding following endoscopic therapy for nonvariceal upper gastrointestinal hemorrhage. Clin Endosc (2011) 1.00

Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression. BMC Med (2016) 0.92

Diagnosis and treatment of perforated or bleeding peptic ulcers: 2013 WSES position paper. World J Emerg Surg (2014) 0.91

Intravenous proton pump inhibitors for peptic ulcer bleeding: Clinical benefits and limits. World J Gastrointest Endosc (2011) 0.87

A randomized controlled trial comparing two different dosages of infusional pantoprazole in peptic ulcer bleeding. Br J Clin Pharmacol (2010) 0.86

Update on the endoscopic management of peptic ulcer bleeding. Curr Gastroenterol Rep (2011) 0.84

A clinical guide to using intravenous proton-pump inhibitors in reflux and peptic ulcers. Therap Adv Gastroenterol (2010) 0.84

Diagnosis and therapy of non-variceal upper gastrointestinal bleeding. World J Gastrointest Pharmacol Ther (2015) 0.82

Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis. J Clin Gastroenterol (2012) 0.80

Is the era of intravenous proton pump inhibitors coming to an end in patients with bleeding peptic ulcers? Meta-analysis of the published literature. Br J Clin Pharmacol (2016) 0.80

Timing or Dosing of Intravenous Proton Pump Inhibitors in Acute Upper Gastrointestinal Bleeding Has Low Impact on Costs. Am J Gastroenterol (2016) 0.80

Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy. BMC Gastroenterol (2012) 0.80

Pharmacological Treatment in Upper Gastrointestinal Bleeding. Curr Treat Options Gastroenterol (2015) 0.78

Consensus on control of risky nonvariceal upper gastrointestinal bleeding in Taiwan with National Health Insurance. Biomed Res Int (2014) 0.78

Endoscopy: Risk assessment in upper gastrointestinal bleeding. Nat Rev Gastroenterol Hepatol (2010) 0.77

Successful Endoscopic Hemostasis Is a Protective Factor for Rebleeding and Mortality in Patients with Nonvariceal Upper Gastrointestinal Bleeding. Dig Dis Sci (2016) 0.76

Management by the intensivist of gastrointestinal bleeding in adults and children. Ann Intensive Care (2012) 0.76

Managing peptic ulcer and gastroesophageal reflux disease in elderly Chinese patients--focus on esomeprazole. Clin Interv Aging (2013) 0.76

Ulcer: Prediction and prevention of peptic ulcer rebleeding. Nat Rev Gastroenterol Hepatol (2011) 0.76

Recent advances in peptic ulcer bleeding. F1000 Med Rep (2009) 0.75

Endoscopy for upper gastrointestinal bleeding: is routine second-look necessary? Nat Rev Gastroenterol Hepatol (2009) 0.75

Greek results of the "ENERGIB" European study on non-variceal upper gastrointestinal bleeding. Ann Gastroenterol (2012) 0.75

Missed opportunities in the trial on proton-pump inhibitor therapy in bleeding peptic ulcers. Ann Intern Med (2009) 0.75

Ulcers: adjuvant PPIs to prevent major ulcer bleeds. Nat Rev Gastroenterol Hepatol (2009) 0.75

Missed opportunities in the trial on proton-pump inhibitor therapy in bleeding peptic ulcers. Ann Intern Med (2009) 0.75

Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding. Curr Gastroenterol Rep (2009) 0.75

Timing of rebleeding in high-risk peptic ulcer bleeding after successful hemostasis: a systematic review. Can J Gastroenterol Hepatol (2014) 0.75

Missed opportunities in the trial on proton-pump inhibitor therapy in bleeding peptic ulcers. Ann Intern Med (2009) 0.75

Management of peptic ulcer bleeding in different case volume workplaces: results of a nationwide inquiry in hungary. Gastroenterol Res Pract (2012) 0.75

Reassessment of Rebleeding Risk of Forrest IB (Oozing) Peptic Ulcer Bleeding in a Large International Randomized Trial. Am J Gastroenterol (2017) 0.75

Risk factors determining the need for second-look endoscopy for peptic ulcer bleeding after endoscopic hemostasis and proton pump inhibitor infusion. Endosc Int Open (2016) 0.75

Comparing intravenous and oral proton pump inhibitor therapy for bleeding peptic ulcers following endoscopic management: a systematic review and meta-analysis. Br J Clin Pharmacol (2017) 0.75

Doppler Endoscopic Probe Monitoring of Blood Flow Improves Risk Stratification and Outcomes of Patients With Severe Nonvariceal Upper Gastrointestinal Hemorrhage. Gastroenterology (2017) 0.75

Articles by these authors

Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut (2012) 12.62

Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med (2010) 8.40

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Pathogenesis of Helicobacter pylori infection. Clin Microbiol Rev (2006) 7.72

International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med (2010) 6.36

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Prevalence of Barrett's esophagus in the general population: an endoscopic study. Gastroenterology (2005) 5.77

Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial. Lancet Oncol (2011) 5.72

Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial. JAMA (2011) 4.74

New oral anticoagulants increase risk for gastrointestinal bleeding: a systematic review and meta-analysis. Gastroenterology (2013) 4.58

Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective study. Gastroenterology (2003) 3.93

Risk of esophageal adenocarcinoma and mortality in patients with Barrett's esophagus: a systematic review and meta-analysis. Clin Gastroenterol Hepatol (2009) 3.66

Management of patients with ulcer bleeding. Am J Gastroenterol (2012) 3.60

The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44

The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26

Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands. Gastroenterology (2008) 3.18

Competence measurement during colonoscopy training: the use of self-assessment of performance measures. Am J Gastroenterol (2012) 3.17

Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15

Canadian Association of Gastroenterology consensus guidelines on safety and quality indicators in endoscopy. Can J Gastroenterol (2012) 3.15

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology (2005) 3.10

Cost-effectiveness analysis of a quantitative immunochemical test for colorectal cancer screening. Gastroenterology (2011) 3.08

Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. Gastroenterology (2005) 2.90

Patient nonadherence to medication in inflammatory bowel disease. Am J Gastroenterol (2003) 2.86

Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process. Gastroenterology (2012) 2.68

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet (2007) 2.48

Laparoscopic Heller's myotomy versus pneumatic dilation in the treatment of idiopathic achalasia: a meta-analysis of randomized, controlled trials. Gastrointest Endosc (2013) 2.46

Stent versus gastrojejunostomy for the palliation of gastric outlet obstruction: a systematic review. BMC Gastroenterol (2007) 2.26

Double balloon enteroscopy and capsule endoscopy for obscure gastrointestinal bleeding: an updated meta-analysis. J Gastroenterol Hepatol (2011) 2.24

Chronic gastrointestinal ischaemia: shifting paradigms. Gut (2010) 2.23

Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors. Am J Gastroenterol (2006) 2.21

High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report. Scand J Gastroenterol (2005) 2.13

Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nat Genet (2013) 2.10

Colorectal neoplasia in veterans is associated with Barrett's esophagus but not with proton-pump inhibitor or aspirin/NSAID use. Gastrointest Endosc (2006) 2.10

Risk factors for erosive esophagitis: a multivariate analysis based on the ProGERD study initiative. Am J Gastroenterol (2004) 2.09

Quality evaluation of colonoscopy reporting and colonoscopy performance in daily clinical practice. Gastrointest Endosc (2011) 2.09

Vaccination coverage in immunosuppressed patients: results of a regional health services research study. Dtsch Arztebl Int (2011) 2.06

High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome. Gut (2011) 2.06

Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentre randomised trial. Lancet (2004) 2.06

Randomized prospective study of endoscopic rubber band ligation compared with bipolar coagulation for chronically bleeding internal hemorrhoids. Am J Gastroenterol (2009) 2.00

A case series of proton pump inhibitor-induced hypomagnesemia. Am J Kidney Dis (2010) 1.99

Majority of patients with inflammatory bowel disease in clinical remission have mucosal inflammation. Inflamm Bowel Dis (2011) 1.97

Surgical gastrojejunostomy or endoscopic stent placement for the palliation of malignant gastric outlet obstruction (SUSTENT study): a multicenter randomized trial. Gastrointest Endosc (2009) 1.97

Proton pump inhibitors reduce the risk of neoplastic progression in patients with Barrett's esophagus. Clin Gastroenterol Hepatol (2012) 1.96

A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study. Am J Gastroenterol (2005) 1.94

The yield and the predictors of esophageal pathology when upper endoscopy is used for the initial evaluation of dysphagia. Gastrointest Endosc (2005) 1.93

Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based Kalixanda study. Gut (2006) 1.92

Cure of Barrett's carcinoma by ifosfamide chemotherapy. Eur J Gastroenterol Hepatol (2002) 1.92

Patterns of antibiotic use and risk of hospital admission because of Clostridium difficile infection. CMAJ (2008) 1.91

Effect of rising chemotherapy costs on the cost savings of colorectal cancer screening. J Natl Cancer Inst (2009) 1.89

Differences in proximal serrated polyp detection among endoscopists are associated with variability in withdrawal time. Gastrointest Endosc (2013) 1.87

Defective cellular localization of mutant ATP7B in Wilson's disease patients and hepatoma cell lines. Gastroenterology (2003) 1.86

Endoscopic therapy versus medical therapy for bleeding peptic ulcer with adherent clot: a meta-analysis. Gastroenterology (2005) 1.85

Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expression. Microbiology (2005) 1.85

Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial. Circulation (2012) 1.84

Chronic pancreatitis--definition, etiology, investigation and treatment. Dtsch Arztebl Int (2013) 1.82

Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum Mutat (2006) 1.80

CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? Gut (2012) 1.77

Electrocautery therapy for refractory anastomotic strictures of the esophagus. Gastrointest Endosc (2006) 1.76

Ectopic varices. Gastrointest Endosc (2011) 1.75

Single-balloon-assisted colonoscopy in patients with previously failed colonoscopy. Gastrointest Endosc (2010) 1.74

The risk of inflammatory bowel disease-related colorectal carcinoma is limited: results from a nationwide nested case-control study. Am J Gastroenterol (2010) 1.73

Phase 3 randomized, placebo-controlled, double-blind study of high-dose continuous infusion cytarabine alone or with laromustine (VNP40101M) in patients with acute myeloid leukemia in first relapse. Blood (2009) 1.72

Therapeutic delay and survival after surgery for cancer of the pancreatic head with or without preoperative biliary drainage. Ann Surg (2010) 1.70

ERCP as an outpatient treatment: a review. Gastrointest Endosc (2008) 1.68

Risk of malignant progression in patients with Barrett's oesophagus: a Dutch nationwide cohort study. Gut (2010) 1.68

Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus. Gastrointest Endosc (2005) 1.66

Are fecal immunochemical test characteristics influenced by sample return time? A population-based colorectal cancer screening trial. Am J Gastroenterol (2011) 1.66

Pathogenesis and treatment of Budd-Chiari syndrome combined with portal vein thrombosis. Am J Gastroenterol (2006) 1.66

A randomized comparison of electrocautery incision with Savary bougienage for relief of anastomotic gastroesophageal strictures. Gastrointest Endosc (2009) 1.66

Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis. Gut (2009) 1.65

Challenges in the management of acute peptic ulcer bleeding. Lancet (2013) 1.65

Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease. Sci Transl Med (2014) 1.64

Esophageal stents with antireflux valve for tumors of the distal esophagus and gastric cardia: a randomized trial. Gastrointest Endosc (2004) 1.64

Prospective follow-up data from the ProGERD study suggest that GERD is not a categorial disease. Am J Gastroenterol (2006) 1.62

Labeled versus unlabeled discrete choice experiments in health economics: an application to colorectal cancer screening. Value Health (2009) 1.61

Diverse functional properties of Wilson disease ATP7B variants. Gastroenterology (2012) 1.61

Helicobacter pylori and antimicrobial resistance: molecular mechanisms and clinical implications. Lancet Infect Dis (2006) 1.60

Aneuploidy and overexpression of Ki67 and p53 as markers for neoplastic progression in Barrett's esophagus: a case-control study. Am J Gastroenterol (2009) 1.60

Comparing the diagnostic yields of technologists and radiologists in an invitational colorectal cancer screening program performed with CT colonography. Radiology (2012) 1.60

Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer. Clin Cancer Res (2011) 1.59

The Global Rating Scale in clinical practice: a comprehensive quality assurance programme for endoscopy departments. Dig Liver Dis (2012) 1.59

Accuracy of narrow-band imaging in predicting colonoscopy surveillance intervals and histology of distal diminutive polyps: results from a multicenter, prospective trial. Gastrointest Endosc (2013) 1.58

Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: results from the CLASSIC I Trial. J Clin Oncol (2012) 1.58

Self-expandable metallic stents for malignant duodenal obstruction caused by biliary tract cancer. Gastrointest Endosc (2003) 1.57

Ingestion of acid and alkaline agents: outcome and prognostic value of early upper endoscopy. Gastrointest Endosc (2004) 1.57

Endoscopic treatment of esophagogastric variceal bleeding in patients with noncirrhotic extrahepatic portal vein thrombosis: a long-term follow-up study. Gastrointest Endosc (2008) 1.56

The use of clinical, histologic, and serologic parameters to predict the intragastric extent of intestinal metaplasia: a recommendation for routine practice. Gastrointest Endosc (2009) 1.56

Limited ability of the proton-pump inhibitor test to identify patients with gastroesophageal reflux disease. Clin Gastroenterol Hepatol (2012) 1.54

Adenoma detection with cap-assisted colonoscopy versus regular colonoscopy: a randomised controlled trial. Gut (2011) 1.53

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52

Ischemic colitis as a cause of severe hematochezia: risk factors and outcomes compared with other colon diagnoses. Gastrointest Endosc (2011) 1.51

Bile acid-stimulated expression of the farnesoid X receptor enhances the immune response in Barrett esophagus. Am J Gastroenterol (2008) 1.51

Clinical consequences of videocapsule endoscopy in GI bleeding and Crohn's disease. Gastrointest Endosc (2007) 1.50

The incidence and risk factors of metachronous colorectal cancer: an indication for follow-up. Dis Colon Rectum (2012) 1.49

Prospective multicenter evaluation of fecal tumor pyruvate kinase type M2 (M2-PK) as a screening biomarker for colorectal neoplasia. Int J Cancer (2006) 1.48

Coumarin-induced intramural hematoma of the duodenum: case report and review of the literature. Scand J Gastroenterol (2010) 1.48

Card15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation. Am J Gastroenterol (2003) 1.47