PubRank

Alexander Shekhtman

Author PubWeight™ 45.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR). Nat Methods 2006 2.15
2 Advanced glycation end product recognition by the receptor for AGEs. Structure 2011 1.84
3 Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE). J Biol Chem 2008 1.51
4 Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction. Proc Natl Acad Sci U S A 2004 1.51
5 Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches. J Biol Chem 2006 1.40
6 Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMR. Proc Natl Acad Sci U S A 2002 1.36
7 Biosynthesis of a fully functional cyclotide inside living bacterial cells. Chembiochem 2007 1.25
8 Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I. Chembiochem 2009 1.24
9 Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets. BMC Biol 2010 1.14
10 A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding. Chem Biol 2008 1.11
11 Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. J Med Chem 2012 1.10
12 Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin. Angew Chem Int Ed Engl 2010 1.07
13 Screening of small molecule interactor library by using in-cell NMR spectroscopy (SMILI-NMR). J Med Chem 2009 1.05
14 Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J Biol Chem 2011 1.04
15 Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function. BMC Biochem 2009 1.03
16 NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility. Biochem Biophys Res Commun 2009 1.03
17 The receptor for advanced glycation end products (RAGE) specifically recognizes methylglyoxal-derived AGEs. Biochemistry 2014 1.02
18 In-cell NMR for protein-protein interactions (STINT-NMR). Nat Protoc 2006 1.02
19 In-cell biochemistry using NMR spectroscopy. PLoS One 2008 0.97
20 Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions. Angew Chem Int Ed Engl 2013 0.94
21 Disulfide bridges remain intact while native insulin converts into amyloid fibrils. PLoS One 2012 0.94
22 Segmental isotopic labeling for structural biological applications of NMR. Methods Mol Biol 2004 0.92
23 Role of the interdomain linker in distance determination for remote cleavage by homing endonuclease I-TevI. J Mol Biol 2008 0.90
24 One RNA aptamer sequence, two structures: a collaborating pair that inhibits AMPA receptors. Nucleic Acids Res 2009 0.89
25 In-cell NMR spectroscopy. Prog Nucl Magn Reson Spectrosc 2010 0.88
26 Palmitic Acid Is a Novel CD4 Fusion Inhibitor That Blocks HIV Entry and Infection. AIDS Res Hum Retroviruses 2009 0.87
27 Recombinant production of rhesus θ-defensin-1 (RTD-1) using a bacterial expression system. Mol Biosyst 2012 0.85
28 Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins. Biochemistry 2011 0.84
29 Structure of proteins in eukaryotic compartments. J Am Chem Soc 2012 0.84
30 Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR. PLoS One 2013 0.83
31 The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol Biol Cell 2014 0.83
32 Increased hydrophobicity and decreased backbone flexibility explain the lower solubility of a cataract-linked mutant of γD-crystallin. J Mol Biol 2011 0.82
33 Using singular value decomposition to characterize protein-protein interactions by in-cell NMR spectroscopy. Chembiochem 2014 0.82
34 Combinatorial library of improved peptide aptamers, CLIPs to inhibit RAGE signal transduction in mammalian cells. PLoS One 2013 0.81
35 Structural biology: Inside the living cell. Nature 2009 0.81
36 Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. PLoS One 2010 0.79
37 Efficient one-pot cyclization/folding of Rhesus θ-defensin-1 (RTD-1). Bioorg Med Chem Lett 2012 0.79
38 Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density. J Biomol NMR 2010 0.78
39 Inhibition of HIV-1 infection in ex vivo cervical tissue model of human vagina by palmitic acid; implications for a microbicide development. PLoS One 2011 0.77
40 Segmental labeling to study multidomain proteins. Adv Exp Med Biol 2012 0.76
41 Specific RNA-protein interactions detected with saturation transfer difference NMR. RNA Biol 2013 0.76
42 Pyrazinamide, but not pyrazinoic acid, is a competitive inhibitor of NADPH binding to Mycobacterium tuberculosis fatty acid synthase I. Bioorg Med Chem Lett 2011 0.76
43 Molecular mechanism of the chaperone function of mini-α-crystallin, a 19-residue peptide of human α-crystallin. Biochemistry 2014 0.76
44 The STINT-NMR method for studying in-cell protein-protein interactions. Curr Protoc Protein Sci 2010 0.76
45 Analogs of the antituberculous agent pyrazinamide are competitive inhibitors of NADPH binding to M. tuberculosis fatty acid synthase I. Chem Biodivers 2012 0.75