Structural biology: Inside the living cell.

Screening of small molecule interactor library by using in-cell NMR spectroscopy (SMILI-NMR). J Med Chem (2009) 1.05

Ion-mediated RNA structural collapse: effect of spatial confinement. Biophys J (2012) 0.85

Nuclear hormone receptor architecture - form and dynamics: The 2009 FASEB Summer Conference on Dynamic Structure of the Nuclear Hormone Receptors. Nucl Recept Signal (2009) 0.77

The STINT-NMR method for studying in-cell protein-protein interactions. Curr Protoc Protein Sci (2010) 0.76

High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature (2009) 2.06

Protein structure determination in living cells by in-cell NMR spectroscopy. Nature (2009) 1.71

Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes. Proc Natl Acad Sci U S A (2006) 1.70

High-resolution macromolecular NMR spectroscopy inside living cells. J Am Chem Soc (2001) 1.45

Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR). Nat Methods (2006) 2.15

Advanced glycation end product recognition by the receptor for AGEs. Structure (2011) 1.84

Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE). J Biol Chem (2008) 1.51

Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction. Proc Natl Acad Sci U S A (2004) 1.51

Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches. J Biol Chem (2006) 1.40

Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMR. Proc Natl Acad Sci U S A (2002) 1.36

Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila. Proc Natl Acad Sci U S A (2005) 1.36

Biosynthesis of a fully functional cyclotide inside living bacterial cells. Chembiochem (2007) 1.25

Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I. Chembiochem (2009) 1.24

Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets. BMC Biol (2010) 1.14

A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding. Chem Biol (2008) 1.11

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. J Med Chem (2012) 1.10

Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin. Angew Chem Int Ed Engl (2010) 1.07

Screening of small molecule interactor library by using in-cell NMR spectroscopy (SMILI-NMR). J Med Chem (2009) 1.05

Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J Biol Chem (2011) 1.04

NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility. Biochem Biophys Res Commun (2009) 1.03

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function. BMC Biochem (2009) 1.03

In-cell NMR for protein-protein interactions (STINT-NMR). Nat Protoc (2006) 1.02

The receptor for advanced glycation end products (RAGE) specifically recognizes methylglyoxal-derived AGEs. Biochemistry (2014) 1.02

In-cell biochemistry using NMR spectroscopy. PLoS One (2008) 0.97

Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions. Angew Chem Int Ed Engl (2013) 0.94

Disulfide bridges remain intact while native insulin converts into amyloid fibrils. PLoS One (2012) 0.94

Segmental isotopic labeling for structural biological applications of NMR. Methods Mol Biol (2004) 0.92

Inhibition of biofilm formation, quorum sensing and infection in Pseudomonas aeruginosa by natural products-inspired organosulfur compounds. PLoS One (2012) 0.91

Role of the interdomain linker in distance determination for remote cleavage by homing endonuclease I-TevI. J Mol Biol (2008) 0.90

One RNA aptamer sequence, two structures: a collaborating pair that inhibits AMPA receptors. Nucleic Acids Res (2009) 0.89

In-cell NMR spectroscopy. Prog Nucl Magn Reson Spectrosc (2010) 0.88

Palmitic Acid Is a Novel CD4 Fusion Inhibitor That Blocks HIV Entry and Infection. AIDS Res Hum Retroviruses (2009) 0.87

Recombinant production of rhesus θ-defensin-1 (RTD-1) using a bacterial expression system. Mol Biosyst (2012) 0.85

Structure of proteins in eukaryotic compartments. J Am Chem Soc (2012) 0.84

Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins. Biochemistry (2011) 0.84

Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR. PLoS One (2013) 0.83

The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol Biol Cell (2014) 0.83

Increased hydrophobicity and decreased backbone flexibility explain the lower solubility of a cataract-linked mutant of γD-crystallin. J Mol Biol (2011) 0.82

Using singular value decomposition to characterize protein-protein interactions by in-cell NMR spectroscopy. Chembiochem (2014) 0.82

Combinatorial library of improved peptide aptamers, CLIPs to inhibit RAGE signal transduction in mammalian cells. PLoS One (2013) 0.81

Peptide aptamers: development and applications. Curr Top Med Chem (2015) 0.80

Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. PLoS One (2010) 0.79

Efficient one-pot cyclization/folding of Rhesus θ-defensin-1 (RTD-1). Bioorg Med Chem Lett (2012) 0.79

Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density. J Biomol NMR (2010) 0.78

Inhibition of HIV-1 infection in ex vivo cervical tissue model of human vagina by palmitic acid; implications for a microbicide development. PLoS One (2011) 0.77

Molecular mechanism of the chaperone function of mini-α-crystallin, a 19-residue peptide of human α-crystallin. Biochemistry (2014) 0.76

Pyrazinamide, but not pyrazinoic acid, is a competitive inhibitor of NADPH binding to Mycobacterium tuberculosis fatty acid synthase I. Bioorg Med Chem Lett (2011) 0.76

The STINT-NMR method for studying in-cell protein-protein interactions. Curr Protoc Protein Sci (2010) 0.76

Segmental labeling to study multidomain proteins. Adv Exp Med Biol (2012) 0.76

Specific RNA-protein interactions detected with saturation transfer difference NMR. RNA Biol (2013) 0.76

Analogs of the antituberculous agent pyrazinamide are competitive inhibitors of NADPH binding to M. tuberculosis fatty acid synthase I. Chem Biodivers (2012) 0.75