Published in Biologicals on March 04, 2009
Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models. Semin Hematol (2013) 0.86
T cells expressing a LMP1-specific chimeric antigen receptor mediate antitumor effects against LMP1-positive nasopharyngeal carcinoma cells in vitro and in vivo. J Biomed Res (2014) 0.83
Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury. J Control Release (2013) 0.80
Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells. J Immunol Res (2016) 0.75
Enhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin. Stem Cells Transl Med (2014) 0.75
Efficacy of cytokine-induced killer cells in the treatment of elderly patients with metastatic pancreatic adenocarcinoma. Cent Eur J Immunol (2015) 0.75
Efficacy of RetroNectin-activated cytokine-induced killer cell therapy in the treatment of advanced hepatocelluar carcinoma. Oncol Lett (2016) 0.75
"Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors. Mol Ther Methods Clin Dev (2016) 0.75
Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency. Mol Ther (2017) 0.75
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell (2008) 10.49
A highly annotated whole-genome sequence of a Korean individual. Nature (2009) 6.91
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Generation of transgenic non-human primates with germline transmission. Nature (2009) 4.06
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell (2011) 4.04
The role of stromal stem cells in tissue regeneration and wound repair. Science (2009) 2.51
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet (2007) 2.39
Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP. Diabetes (2007) 2.34
Self-formation of functional adenohypophysis in three-dimensional culture. Nature (2011) 2.34
Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci U S A (2005) 2.31
IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages. Blood (2003) 2.01
Efficient colonic mucosal wound repair requires Trem2 signaling. Proc Natl Acad Sci U S A (2008) 1.93
CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med (2003) 1.82
In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. FASEB J (2005) 1.80
Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice. Gastroenterology (2012) 1.77
Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference. Oncogene (2004) 1.76
Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia. Circulation (2007) 1.75
Surgical stress promotes tumor growth in ovarian carcinoma. Clin Cancer Res (2009) 1.73
Transforming growth factor-beta1 is a molecular target for the peroxisome proliferator-activated receptor delta. Circ Res (2007) 1.70
Dissolution chemistry and biocompatibility of single-crystalline silicon nanomembranes and associated materials for transient electronics. ACS Nano (2014) 1.66
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol (2006) 1.64
Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proc Natl Acad Sci U S A (2001) 1.63
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res (2002) 1.62
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. Cancer Res (2002) 1.60
Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model. FASEB J (2006) 1.59
Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals. Proc Natl Acad Sci U S A (2008) 1.54
A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype. PLoS One (2013) 1.51
Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr Biol (2005) 1.49
Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. EMBO J (2013) 1.47
Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models. Neuropsychopharmacology (2007) 1.45
Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells. PLoS One (2013) 1.43
Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells. J Gene Med (2004) 1.43
Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation. Gastroenterology (2007) 1.42
Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial. Eur J Anaesthesiol (2012) 1.42
Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation. J Biol Chem (2006) 1.39
Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem (2010) 1.37
EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma. J Natl Cancer Inst (2009) 1.37
The first generation of a BAC-based physical map of Brassica rapa. BMC Genomics (2008) 1.34
Development and validation of a quantitative real-time polymerase chain reaction classifier for lung cancer prognosis. J Thorac Oncol (2011) 1.32
Dual targeting of EphA2 and FAK in ovarian carcinoma. Cancer Biol Ther (2009) 1.30
The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Gene Expr Patterns (2005) 1.30
In vivo bone formation from human embryonic stem cell-derived osteogenic cells in poly(d,l-lactic-co-glycolic acid)/hydroxyapatite composite scaffolds. Biomaterials (2007) 1.29
Adenosine generation and signaling during acute kidney injury. J Am Soc Nephrol (2011) 1.25
Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/gamma c(null) immunodeficient mice. Proc Natl Acad Sci U S A (2007) 1.25
Retinoblastoma protein regulates cell proliferation, differentiation, and endoreduplication in plants. Plant J (2005) 1.23
Gene expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells. Mol Cancer (2007) 1.22
Characterization of a stem cell population in lung cancer A549 cells. Biochem Biophys Res Commun (2008) 1.22
Inhibition of pluripotent stem cell-derived teratoma formation by small molecules. Proc Natl Acad Sci U S A (2013) 1.22
Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia. PLoS One (2012) 1.21
Primary bone-derived cells induce osteogenic differentiation without exogenous factors in human embryonic stem cells. Biochem Biophys Res Commun (2005) 1.19
Depletion of UDP-D-apiose/UDP-D-xylose synthases results in rhamnogalacturonan-II deficiency, cell wall thickening, and cell death in higher plants. J Biol Chem (2006) 1.18
Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study. PLoS One (2010) 1.18
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells. FEBS Lett (2010) 1.18
Serial cloning of pigs by somatic cell nuclear transfer: restoration of phenotypic normality during serial cloning. Dev Dyn (2007) 1.17
Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. PLoS One (2012) 1.17
Inefficient reprogramming of the hematopoietic stem cell genome following nuclear transfer. J Cell Sci (2006) 1.15
Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration. Mol Cell Biol (2006) 1.14
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery. EMBO J (2007) 1.14
Detection of thyroid system-disrupting chemicals using in vitro and in vivo screening assays in Xenopus laevis. Toxicol Sci (2005) 1.13
Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. J Immunol (2010) 1.12
Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway. Genome Res (2003) 1.12
Partial netrin-1 deficiency aggravates acute kidney injury. PLoS One (2011) 1.11
Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEB J (2002) 1.11
Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes. Blood (2005) 1.10
Effective inhibition of cell growth and invasion of melanoma by combined suppression of BRAF (V599E) and Skp2 with lentiviral RNAi. Int J Cancer (2006) 1.09
The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice. PLoS One (2012) 1.09
Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages. Blood (2006) 1.09
Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs. Sci Rep (2013) 1.08
RNA interfering approach for clarifying the PPARgamma pathway using lentiviral vector expressing short hairpin RNA. FEBS Lett (2004) 1.07
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. J Clin Invest (2013) 1.07
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. J Natl Cancer Inst (2009) 1.07
Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling. Proc Natl Acad Sci U S A (2012) 1.07
Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells. Exp Hematol (2002) 1.06
Unique and selective effects of five Ets family members, Elf3, Ets1, Ets2, PEA3, and PU.1, on the promoter of the type II transforming growth factor-beta receptor gene. J Biol Chem (2004) 1.06
Lentiviral vector-mediated SERCA2 gene transfer protects against heart failure and left ventricular remodeling after myocardial infarction in rats. Mol Ther (2008) 1.05
Bone marrow mononuclear cells have neurovascular tropism and improve diabetic neuropathy. Stem Cells (2009) 1.04
Visualization of spatiotemporal activation of Notch signaling: live monitoring and significance in neural development. Dev Biol (2005) 1.04
Optimization of 25 kDa linear polyethylenimine for efficient gene delivery. Biologicals (2006) 1.03
Novel embryoid body-based method to derive mesenchymal stem cells from human embryonic stem cells. Tissue Eng Part A (2010) 1.03
Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development. Proc Natl Acad Sci U S A (2012) 1.03
Differential contribution of NFATc2 and NFATc1 to TNF-alpha gene expression in T cells. J Immunol (2008) 1.02
Stable embryonic stem cell lines in rabbits: potential small animal models for human research. Reprod Biomed Online (2008) 1.02
Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models. Mol Pharmacol (2005) 1.01
Efficiency of the elongation factor-1alpha promoter in mammalian embryonic stem cells using lentiviral gene delivery systems. Stem Cells Dev (2007) 1.01
A targeted mutation of Nkd1 impairs mouse spermatogenesis. J Biol Chem (2004) 1.01
Lidocaine does not prevent bispectral index increases in response to endotracheal intubation. Anesth Analg (2006) 1.01
Coincident elevation of cAMP and calcium influx by PACAP-27 synergistically regulates vasoactive intestinal polypeptide gene transcription through a novel PKA-independent signaling pathway. J Neurosci (2002) 1.01
Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling. J Biol Chem (2007) 1.00
Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48-c-Kit+Sca-1+lineage marker- cell population. Stem Cells (2007) 1.00
Methylation status of differentially methylated regions at Igf2/H19 locus in porcine gametes and preimplantation embryos. Genomics (2008) 0.99
Analysis of protein complexes through model-based biclustering of label-free quantitative AP-MS data. Mol Syst Biol (2010) 0.99
Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects. Biol Reprod (2009) 0.99
Primed pluripotent cell lines derived from various embryonic origins and somatic cells in pig. PLoS One (2013) 0.99