Published in Am J Physiol Endocrinol Metab on March 10, 2009
Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity. Horm Behav (2010) 1.98
Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes. Diabetologia (2009) 0.89
Hunting for the SNARK in metabolic disease. Am J Physiol Endocrinol Metab (2009) 0.83
Meglumine exerts protective effects against features of metabolic syndrome and type II diabetes. PLoS One (2014) 0.76
Corticosterone administration in drinking water decreases high-fat diet intake but not preference in male rats. Am J Physiol Regul Integr Comp Physiol (2016) 0.76
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal. J Exp Med (2006) 3.78
Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res (2009) 3.50
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev (2011) 2.97
Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites. Cancer (2004) 2.67
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res (2007) 2.39
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation. Oncogene (2002) 2.01
Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci (2008) 1.87
Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Cancer Res (2006) 1.73
Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise. FASEB J (2004) 1.65
Massive transcriptional start site analysis of human genes in hypoxia cells. Nucleic Acids Res (2009) 1.60
Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. Proc Natl Acad Sci U S A (2010) 1.48
Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein. J Biol Chem (2002) 1.44
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A (2009) 1.34
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner. Biochem Biophys Res Commun (2004) 1.34
Risk of multiple squamous cell carcinomas both in the esophagus and the head and neck region. Carcinogenesis (2005) 1.32
Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers Arch (2002) 1.31
ARK5 is a tumor invasion-associated factor downstream of Akt signaling. Mol Cell Biol (2004) 1.29
Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech Ageing Dev (2009) 1.29
ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation. Oncogene (2003) 1.25
A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res (2008) 1.22
Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochim Pol (2003) 1.19
Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis. J Thorac Oncol (2014) 1.19
Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry. Metabolomics (2012) 1.17
Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers. Mol Biol Cell (2002) 1.14
Blood flow restriction by low compressive force prevents disuse muscular weakness. J Sci Med Sport (2010) 1.14
ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress. Mol Cell (2011) 1.14
Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice. Cancer Res (2005) 1.10
The development and clinical use of a beam ON-LINE PET system mounted on a rotating gantry port in proton therapy. Int J Radiat Oncol Biol Phys (2010) 1.10
RET fusion gene: translation to personalized lung cancer therapy. Cancer Sci (2013) 1.09
Wasting mechanisms in muscular dystrophy. Int J Biochem Cell Biol (2013) 1.07
Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues. Cancer Lett (2008) 1.07
Long-term trends in cardiorespiratory fitness and the incidence of type 2 diabetes. Diabetes Care (2010) 1.05
Identification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterparts. PLoS One (2013) 1.05
New metallic carbon crystal. Phys Rev Lett (2009) 1.05
Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human. Cancer Res (2006) 1.04
ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma. Oncogene (2005) 1.04
Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation. J Biol Chem (2005) 1.03
Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats. Exp Gerontol (2007) 1.03
Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs. Cancer Sci (2011) 1.03
Regulation of caspase-6 and FLIP by the AMPK family member ARK5. Oncogene (2004) 1.01
An anticancer agent, pyrvinium pamoate inhibits the NADH-fumarate reductase system--a unique mitochondrial energy metabolism in tumour microenvironments. J Biochem (2012) 1.01
Changes in PKB/Akt and calcineurin signaling during recovery in atrophied soleus muscle induced by unloading. Am J Physiol Regul Integr Comp Physiol (2005) 0.99
The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments. Ann N Y Acad Sci (2010) 0.99
Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit. BMC Cancer (2013) 0.99
Hormetic effects of regular exercise in aging: correlation with oxidative stress. Appl Physiol Nutr Metab (2007) 0.98
Hyperthermia induced by microwave diathermy in the management of muscle and tendon injuries. Br Med Bull (2007) 0.98
Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer. Carcinogenesis (2002) 0.97
Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation. FEBS Lett (2004) 0.97
Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma. J Biol Chem (2014) 0.96
Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung. Pathol Int (2013) 0.96
Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program. FASEB J (2013) 0.96
Clinical outcome of Japanese metastatic colorectal cancer patients harbouring the KRAS p.G13D mutation treated with cetuximab + irinotecan. Jpn J Clin Oncol (2012) 0.95
Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers. Acta Biochim Pol (2006) 0.95
ARK5 expression in colorectal cancer and its implications for tumor progression. Am J Pathol (2004) 0.95
Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family. Biochem Biophys Res Commun (2003) 0.95
Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci. Cancer Sci (2007) 0.94
Preliminary results of intensity-modulated radiation therapy with helical tomotherapy for prostate cancer. J Cancer Res Clin Oncol (2012) 0.94
Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition. Bioorg Med Chem (2007) 0.93
Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo. Cancer Sci (2013) 0.93
Single bout of running exercise changes LC3-II expression in rat cardiac muscle. Biochem Biophys Res Commun (2011) 0.93
c-Maf expression in angioimmunoblastic T-cell lymphoma. Am J Surg Pathol (2007) 0.93
Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells' tolerance to nutrient starvation. Cancer Sci (2004) 0.92
Effects of vitamin E deficiency on fatigue and muscle contractile properties. Eur J Appl Physiol (2002) 0.92
Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing. Hugo J (2011) 0.92
Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1 gene induction in human melanoma cell lines. Int J Cancer (2003) 0.92
Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity. J Virol (2004) 0.92
Predicting the severity of systemic inflammatory response syndrome (SIRS)-associated coagulopathy with hemostatic molecular markers and vascular endothelial injury markers. J Trauma (2007) 0.92
Three-dimensional finite element analysis of cartilaginous tissues in human temporomandibular joint during prolonged clenching. Arch Oral Biol (2010) 0.91
Effects of exercise on brain function: role of free radicals. Appl Physiol Nutr Metab (2007) 0.91
Mitochondrial fumarate reductase as a target of chemotherapy: from parasites to cancer cells. Biochim Biophys Acta (2011) 0.91
Foods and beverages in relation to urothelial cancer: case-control study in Japan. Int J Urol (2004) 0.91
Changes in muscle temperature induced by 434 MHz microwave hyperthermia. Br J Sports Med (2007) 0.90
Matrix metalloproteinase-9 inhibition improves proliferation and engraftment of myogenic cells in dystrophic muscle of mdx mice. PLoS One (2013) 0.90
Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation. ChemMedChem (2012) 0.89
Regular exercise: an effective means to reduce oxidative stress in old rats. Ann N Y Acad Sci (2004) 0.89
Bioactive secondary metabolites from Boesenbergia pandurata of Myanmar and their preferential cytotoxicity against human pancreatic cancer PANC-1 cell line in nutrient-deprived medium. J Nat Prod (2007) 0.89
Feasibility and robustness of amplification refractory mutation system (ARMS)-based KRAS testing using clinically available formalin-fixed, paraffin-embedded samples of colorectal cancers. Jpn J Clin Oncol (2010) 0.89
Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle. Br J Sports Med (2007) 0.88
Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase. Am J Physiol Endocrinol Metab (2005) 0.88
Measurement and verification of positron emitter nuclei generated at each treatment site by target nuclear fragment reactions in proton therapy. Med Phys (2010) 0.88
Elevation of body temperature is an essential factor for exercise-increased extracellular heat shock protein 72 level in rat plasma. Am J Physiol Regul Integr Comp Physiol (2008) 0.88
Duration of static stretching influences muscle force production in hamstring muscles. J Strength Cond Res (2007) 0.87
Kigamicins, novel antitumor antibiotics. II. Structure determination. J Antibiot (Tokyo) (2003) 0.87
Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int J Cancer (2008) 0.87