Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMID 19277984)

Published in J Cell Physiol on July 01, 2009

Authors

Jiying Wang1, Kyoko Ohno-Matsui, Takeshi Yoshida, Noriaki Shimada, Shizuko Ichinose, Tetsuji Sato, Manabu Mochizuki, Ikuo Morita

Author Affiliations

1: Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.

Articles citing this

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci U S A (2011) 1.56

The pathogenic role of the canonical Wnt pathway in age-related macular degeneration. Invest Ophthalmol Vis Sci (2009) 1.31

Novel roles for α-crystallins in retinal function and disease. Prog Retin Eye Res (2012) 1.17

The role of the immune response in age-related macular degeneration. Int J Inflam (2013) 1.16

Genetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics. Mol Aspects Med (2012) 1.16

Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PLoS One (2013) 1.04

Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 1.03

Complement dysregulation in AMD: RPE-Bruch's membrane-choroid. Mol Aspects Med (2012) 1.03

A2E accumulation influences retinal microglial activation and complement regulation. Neurobiol Aging (2012) 1.01

Suppression and regression of choroidal neovascularization in mice by a novel CCR2 antagonist, INCB3344. PLoS One (2011) 1.01

Inflammation and its role in age-related macular degeneration. Cell Mol Life Sci (2016) 0.97

Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization. J Biol Chem (2011) 0.96

Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cells. Free Radic Biol Med (2014) 0.95

Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD. Aging (Albany NY) (2013) 0.91

Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration. Prog Retin Eye Res (2015) 0.90

Treatment of dry age-related macular degeneration with dobesilate. BMJ Case Rep (2012) 0.85

Drusen and Pro-inflammatory Mediators in the Post-Mortem Human Eye. J Clin Exp Ophthalmol (2012) 0.83

Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model. PLoS One (2013) 0.83

Recent developments in the management of dry age-related macular degeneration. Clin Ophthalmol (2015) 0.81

Retinal nerve fiber layer thickness and cognitive ability in older people: the Lothian Birth Cohort 1936 study. BMC Ophthalmol (2013) 0.81

Multifunctional antioxidants for the treatment of age-related diseases. J Med Chem (2010) 0.80

Visual and Ocular Manifestations of Alzheimer's Disease and Their Use as Biomarkers for Diagnosis and Progression. Front Neurol (2016) 0.80

Age-Related Macular Degeneration: A Disease of Systemic or Local Complement Dysregulation? J Clin Med (2014) 0.78

Articles by these authors

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med (2005) 3.70

Efficacy, safety, and pharmacokinetics of multiple administration of infliximab in Behçet's disease with refractory uveoretinitis. J Rheumatol (2004) 3.28

Myopia. Lancet (2012) 3.27

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell. Nat Med (2012) 3.17

Nicotinamide suppresses hyperphosphatemia in hemodialysis patients. Kidney Int (2004) 3.12

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. Nat Genet (2010) 2.74

Prevalence and characteristics of foveal retinal detachment without macular hole in high myopia. Am J Ophthalmol (2003) 2.47

International criteria for the diagnosis of ocular sarcoidosis: results of the first International Workshop On Ocular Sarcoidosis (IWOS). Ocul Immunol Inflamm (2009) 2.47

Changes of axial length measured by IOL master during 2 years in eyes of adults with pathologic myopia. Graefes Arch Clin Exp Ophthalmol (2012) 2.08

Comparison of infliximab versus ciclosporin during the initial 6-month treatment period in Behçet disease. Br J Ophthalmol (2009) 1.91

Epidemiological survey of intraocular inflammation in Japan. Jpn J Ophthalmol (2007) 1.84

Genotype-phenotype correlations in alternating hemiplegia of childhood. Neurology (2014) 1.82

Myopic choroidal neovascularization: a 10-year follow-up. Ophthalmology (2003) 1.78

Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol (2010) 1.77

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Cancer Treat Rev (2003) 1.76

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition. EMBO J (2011) 1.71

Extension of corticocortical afferents into the anterior bank of the intraparietal sulcus by tool-use training in adult monkeys. Neuropsychologia (2006) 1.71

Increased diffusivity in superior temporal gyrus in patients with schizophrenia: a Diffusion Tensor Imaging study. Schizophr Res (2009) 1.70

Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis. J Biol Chem (2005) 1.61

Long-term development of significant visual field defects in highly myopic eyes. Am J Ophthalmol (2011) 1.60

Suspended cells from trabecular bone by collagenase digestion become virtually identical to mesenchymal stem cells obtained from marrow aspirates. Blood (2004) 1.60

Synovial stem cells are regionally specified according to local microenvironments after implantation for cartilage regeneration. Stem Cells (2006) 1.58

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan. Blood (2010) 1.57

The potential role of amyloid beta in the pathogenesis of age-related macular degeneration. J Clin Invest (2005) 1.56

Mechanism of stabilization of a bacterial collagen triple helix in the absence of hydroxyproline. J Biol Chem (2007) 1.56

NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition. Genes Dev (2007) 1.53

Long-term pattern of progression of myopic maculopathy: a natural history study. Ophthalmology (2010) 1.51

Biocompatible inkjet printing technique for designed seeding of individual living cells. Tissue Eng (2006) 1.50

In vitro chondrogenesis of human synovium-derived mesenchymal stem cells: optimal condition and comparison with bone marrow-derived cells. J Cell Biochem (2006) 1.47

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli. Protein Expr Purif (2002) 1.46

Therapeutic angiogenesis by implantation of a capillary structure constituted of human adipose tissue microvascular endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.46

Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells (2009) 1.45

Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. Ophthalmology (2010) 1.44

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. PLoS Genet (2009) 1.43

Ocular infiltrating CD4+ T cells from patients with Vogt-Koyanagi-Harada disease recognize human melanocyte antigens. Invest Ophthalmol Vis Sci (2006) 1.41

Neocortical gray matter volume in first-episode schizophrenia and first-episode affective psychosis: a cross-sectional and longitudinal MRI study. Biol Psychiatry (2007) 1.40

Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification. Cancer Res (2007) 1.40

Regression of cardiac hypertrophy in type 2 diabetes with hypertension by candesartan. Diabetes Res Clin Pract (2006) 1.39

Natural course of macular retinoschisis in highly myopic eyes without macular hole or retinal detachment. Am J Ophthalmol (2006) 1.38

Anatomical features of periprostatic tissue and its surroundings: a histological analysis of 79 radical retropubic prostatectomy specimens. Jpn J Clin Oncol (2004) 1.38

Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility. J Virol (2010) 1.37

The gap junction-independent tumor-suppressing effect of connexin 43. J Biol Chem (2003) 1.35

Characteristics of peripapillary detachment in pathologic myopia. Arch Ophthalmol (2006) 1.34

Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease. Arthritis Res Ther (2012) 1.34

Endoscopic diagnosis of early squamous neoplasia of the esophagus with iodine staining: high-grade intra-epithelial neoplasia turns pink within a few minutes. J Gastroenterol Hepatol (2007) 1.33

Evaluation of peripapillary intrachoroidal cavitation with swept source and enhanced depth imaging optical coherence tomography. Retina (2012) 1.32

A comparison of the tube forming potentials of early and late endothelial progenitor cells. Exp Cell Res (2007) 1.32

Detection of Candida and Aspergillus species DNA using broad-range real-time PCR for fungal endophthalmitis. Graefes Arch Clin Exp Ophthalmol (2011) 1.30

Clinical characteristics of posterior staphyloma in eyes with pathologic myopia. Am J Ophthalmol (2008) 1.30

Long-term visual prognosis of choroidal neovascularization in high myopia: a comparison between age groups. Ophthalmology (2002) 1.29

Endoscopic submucosal dissection for treatment of early stage hypopharyngeal carcinoma. Gastrointest Endosc (2006) 1.28

Acquired optic nerve and peripapillary pits in pathologic myopia. Ophthalmology (2012) 1.27

Use of a comprehensive polymerase chain reaction system for diagnosis of ocular infectious diseases. Ophthalmology (2013) 1.25

A training system of orientation and mobility for blind people using acoustic virtual reality. IEEE Trans Neural Syst Rehabil Eng (2010) 1.23

A clinical evaluation of uveitis-associated secondary glaucoma. Jpn J Ophthalmol (2002) 1.22

Cytokine profile in aqueous humor and sera of patients with infectious or noninfectious uveitis. Invest Ophthalmol Vis Sci (2006) 1.22

Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition. Mol Cancer Ther (2010) 1.21

Peripapillary changes detected by optical coherence tomography in eyes with high myopia. Ophthalmology (2007) 1.21

Detection of paravascular lamellar holes and other paravascular abnormalities by optical coherence tomography in eyes with high myopia. Ophthalmology (2007) 1.21

Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells. J Cell Physiol (2004) 1.19

Natural course of myopic traction maculopathy and factors associated with progression or resolution. Am J Ophthalmol (2013) 1.18

Preparation and characterization of decellularized cornea using high-hydrostatic pressurization for corneal tissue engineering. Biomaterials (2010) 1.18

The cutaneous innate immune response in patients with atopic dermatitis. J Allergy Clin Immunol (2013) 1.18

Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. PLoS Genet (2012) 1.17

Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney. J Histochem Cytochem (2007) 1.17

Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats. Br J Nutr (2008) 1.16

Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats. Br J Nutr (2007) 1.15

Prognosis of canine patients with nasal tumors according to modified clinical stages based on computed tomography: a retrospective study. J Vet Med Sci (2008) 1.15

A novel route for connexin 43 to inhibit cell proliferation: negative regulation of S-phase kinase-associated protein (Skp 2). Cancer Res (2003) 1.15

Reduced retinal angiogenesis in MMP-2-deficient mice. Invest Ophthalmol Vis Sci (2003) 1.14

Cisplatin resistance and transcription factors. Curr Med Chem Anticancer Agents (2005) 1.13

Stromal cell-derived factor-1 from biliary epithelial cells recruits CXCR4-positive cells: implications for inflammatory liver diseases. Lab Invest (2003) 1.13