Published in Eur J Nucl Med Mol Imaging on March 14, 2009
Imaging key biomarkers of tumor angiogenesis. Theranostics (2012) 1.03
Design and development of molecular imaging probes. Curr Top Med Chem (2010) 1.02
Site-Specific Labeling of scVEGF with Fluorine-18 for Positron Emission Tomography Imaging. Theranostics (2012) 0.86
New radiotracers for imaging of vascular targets in angiogenesis-related diseases. Adv Drug Deliv Rev (2014) 0.83
Synthesis and in vitro evaluation of [18F](R)-FEPAQ: a potential PET ligand for VEGFR2. Bioorg Med Chem Lett (2012) 0.82
Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts. PLoS One (2012) 0.82
[18 F]FDG-PET imaging is an early non-invasive pharmacodynamic biomarker for a first-in-class dual MEK/Raf inhibitor, RO5126766 (CH5126766), in preclinical xenograft models. EJNMMI Res (2013) 0.77
Theragnostic imaging using radiolabeled antibodies and tyrosine kinase inhibitors. ScientificWorldJournal (2015) 0.75
Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[11C]PAQ. EJNMMI Res (2014) 0.75
Tumor angiogenesis: therapeutic implications. N Engl J Med (1971) 35.36
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Angiogenesis in cancer and other diseases. Nature (2000) 28.28
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell (1996) 23.99
Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (1989) 16.71
The biology of vascular endothelial growth factor. Endocr Rev (1997) 13.70
Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov (2007) 11.46
Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol (2002) 7.76
Tumor induction of VEGF promoter activity in stromal cells. Cell (1998) 5.20
Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drugs (1999) 4.32
Multimodality molecular imaging of tumor angiogenesis. J Nucl Med (2008) 3.99
Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. Cancer Res (2000) 3.14
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc Natl Acad Sci U S A (1995) 2.94
Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev (1999) 2.83
DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice. J Immunol (2000) 2.65
How tumors become angiogenic. Adv Cancer Res (1996) 2.63
Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes (2006) 2.53
Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. Clin Cancer Res (2004) 2.47
Vascular endothelial growth factor localization in the adult. Am J Pathol (2006) 2.20
PET of vascular endothelial growth factor receptor expression. J Nucl Med (2006) 2.18
Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes. Nat Med (2007) 1.99
Redefining the target: chemotherapeutics as antiangiogenics. J Clin Oncol (2001) 1.84
In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft. J Nucl Med (2007) 1.79
In vivo models of angiogenesis. J Cell Mol Med (2006) 1.74
High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol Pharmacol (2004) 1.67
Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice. Cancer Res (2008) 1.61
Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies. J Natl Cancer Inst (2002) 1.52
Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. J Med Chem (2002) 1.45
A new PET tracer specific for vascular endothelial growth factor receptor 2. Eur J Nucl Med Mol Imaging (2007) 1.43
Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression. Front Biosci (2007) 1.33
Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. Expert Opin Investig Drugs (2007) 1.24
Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J Clin Invest (1998) 1.22
The development of [(124)I]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography. Cancer Res (2002) 1.16
Promise and progress for functional and molecular imaging of response to targeted therapies. Pharm Res (2007) 1.11
Challenges for patient selection with VEGF inhibitors. Cancer Chemother Pharmacol (2007) 1.10
Imaging of VEGF receptor in a rat myocardial infarction model using PET. J Nucl Med (2008) 1.09
Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation (2008) 1.07
Pathogenesis of ascites tumor growth: fibrinogen influx and fibrin accumulation in tissues lining the peritoneal cavity. Cancer Res (1995) 1.05
Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy. Recent Pat Anticancer Drug Discov (2007) 1.03
Quantitative PET imaging of VEGF receptor expression. Mol Imaging Biol (2008) 0.98
ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein. Br J Cancer (2007) 0.94
Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo. FASEB J (2007) 0.90
The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities. Cancer Metastasis Rev (1998) 0.87
Tissue distribution and metabolism of the tyrosine kinase inhibitor ZD6474 (Zactima) in tumor-bearing nude mice following oral dosing. J Pharmacol Exp Ther (2006) 0.87
A simple and efficient in vitro method for metabolism studies of radiotracers. Nucl Med Biol (2001) 0.77
Experimental observation of the quantum anomalous Hall effect in a magnetic topological insulator. Science (2013) 4.69
The effect of China's one-child family policy after 25 years. N Engl J Med (2005) 4.14
Vascular endothelial growth factor B controls endothelial fatty acid uptake. Nature (2010) 3.40
Snapin-regulated late endosomal transport is critical for efficient autophagy-lysosomal function in neurons. Neuron (2010) 3.06
Safety and effectiveness of a 2009 H1N1 vaccine in Beijing. N Engl J Med (2010) 2.98
China's excess males, sex selective abortion, and one child policy: analysis of data from 2005 national intercensus survey. BMJ (2009) 2.89
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes. Nature (2012) 2.83
Aldosterone-induced inflammation in the rat heart : role of oxidative stress. Am J Pathol (2002) 2.33
Double-shelled nanocapsules of V2O5-based composites as high-performance anode and cathode materials for Li ion batteries. J Am Chem Soc (2009) 2.09
ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors. Lung Cancer (2007) 1.93
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell (2011) 1.86
Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity. PLoS Genet (2009) 1.72
Structural evolution and the capacity fade mechanism upon long-term cycling in Li-rich cathode material. Phys Chem Chem Phys (2012) 1.69
Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity. Am J Physiol Heart Circ Physiol (2009) 1.68
Induction of autoimmunity by pristane and other naturally occurring hydrocarbons. Trends Immunol (2009) 1.64
Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. Gene (2002) 1.58
Angiomotin regulates endothelial cell-cell junctions and cell motility. J Biol Chem (2005) 1.57
Abacavir induces loading of novel self-peptides into HLA-B*57: 01: an autoimmune model for HLA-associated drug hypersensitivity. AIDS (2012) 1.54
The consequences of son preference and sex-selective abortion in China and other Asian countries. CMAJ (2011) 1.52
A comparison of obstetric maneuvers for the acute management of shoulder dystocia. Obstet Gynecol (2011) 1.51
Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev (2007) 1.49
A simple and precise classification for cleft lip and palate: a five-digit numerical recording system. Cleft Palate Craniofac J (2007) 1.45
Physiological levels of ATP negatively regulate proteasome function. Cell Res (2010) 1.44
Sense of coherence--stability over time and relation to health, disease, and psychosocial changes in a general population: a longitudinal study. Scand J Public Health (2003) 1.37
The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells. Blood (2008) 1.36
Endothelial-directed hepatic regeneration after partial hepatectomy. Ann Surg (2003) 1.34
p130-angiomotin associates to actin and controls endothelial cell shape. FEBS J (2006) 1.31
The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Sci Signal (2013) 1.25
On the selection of a tracer for PET imaging of HER2-expressing tumors: direct comparison of a 124I-labeled affibody molecule and trastuzumab in a murine xenograft model. J Nucl Med (2009) 1.23
Excellent performance in lithium-ion battery anodes: rational synthesis of Co(CO3)0.5(OH)0.11H2O nanobelt array and its conversion into mesoporous and single-crystal Co3O4. ACS Nano (2010) 1.23
Differential roles of p80- and p130-angiomotin in the switch between migration and stabilization of endothelial cells. Biochim Biophys Acta (2007) 1.20
The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cells. J Neurosci (2005) 1.20
AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matrix. Neuro Oncol (2008) 1.18
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation. Nat Commun (2013) 1.13
Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction. Mol Cell Biol (2003) 1.12
Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation. J Neurooncol (2008) 1.11
Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis. Circ Res (2009) 1.10
Aldosteronism and peripheral blood mononuclear cell activation: a neuroendocrine-immune interface. Circ Res (2003) 1.10
Protein kinase C epsilon is overexpressed in primary human non-small cell lung cancers and functionally required for proliferation of non-small cell lung cancer cells in a p21/Cip1-dependent manner. Cancer Res (2007) 1.08
High rate capability caused by surface cubic spinels in Li-rich layer-structured cathodes for Li-ion batteries. Sci Rep (2013) 1.07
The relationship between serum thyrotropin and components of metabolic syndrome. Endocr J (2010) 1.06
Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting. Nat Methods (2004) 1.06
Gender differences in trends of acute myocardial infarction events: the Northern Sweden MONICA study 1985 - 2004. BMC Cardiovasc Disord (2008) 1.05
Biotinylated nanodiamond: simple and efficient functionalization of detonation diamond. Langmuir (2008) 1.03
Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls. Lancet Oncol (2010) 1.03
Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus. Hippocampus (2008) 1.02
Radiolabelled proteins for positron emission tomography: Pros and cons of labelling methods. Biochim Biophys Acta (2010) 1.01
Time trends in symptoms and prehospital delay time in women vs. men with myocardial infarction over a 15-year period. The Northern Sweden MONICA Study. Eur J Cardiovasc Nurs (2007) 1.01
Loss of responsiveness to chemotactic factors by deletion of the C-terminal protein interaction site of angiomotin. J Cell Sci (2003) 1.01
Smoking, cessation and expenditure in low income Chinese: cross sectional survey. BMC Public Health (2007) 1.01
The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells. J Immunol (2011) 0.99
Angiomotin expression promotes hemangioendothelioma invasion. Oncogene (2004) 0.99
BMP2 genetically engineered MSCs and EPCs promote vascularized bone regeneration in rat critical-sized calvarial bone defects. PLoS One (2013) 0.98
Natural variation in Ghd7.1 plays an important role in grain yield and adaptation in rice. Cell Res (2013) 0.98
Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes. Free Radic Biol Med (2011) 0.98
Wip1 regulates the generation of new neural cells in the adult olfactory bulb through p53-dependent cell cycle control. Stem Cells (2009) 0.97
Angiomotin and angiomotin like proteins, their expression and correlation with angiogenesis and clinical outcome in human breast cancer. BMC Cancer (2006) 0.96
Stress and psychosomatic symptoms in Chinese school children: cross-sectional survey. Arch Dis Child (2010) 0.96
A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors. Angiogenesis (2012) 0.96
Li-rich thin film cathode prepared by pulsed laser deposition. Sci Rep (2013) 0.96
Temporal and spatial characteristics of apoptosis in the infarcted rat heart. Biochem Biophys Res Commun (2004) 0.95
Pleuropulmonary desmoid tumors: immunohistochemical comparison with solitary fibrous tumors and assessment of beta-catenin and cyclin D1 expression. Arch Pathol Lab Med (2006) 0.95
Strong superconducting proximity effect in pb-bi(2)te(3) hybrid structures. Sci Rep (2012) 0.95
The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments. J Immunol (2008) 0.94
A 60-year review on the changing epidemiology of measles in capital Beijing, China, 1951-2011. BMC Public Health (2013) 0.94
A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene. Drug Metab Dispos (2003) 0.93
p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy. Breast Cancer Res (2006) 0.92
Detection and evaluation of immunofunction of patients with severe fever with thrombocytopenia syndrome. Clin Exp Med (2013) 0.91
Decreased GFR estimated by MDRD or Cockcroft-Gault equation predicts incident CVD: the strong heart study. J Nephrol (2009) 0.91
Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo. FASEB J (2007) 0.90
Designed functional systems from peapod-like Co@carbon to Co3O4@carbon nanocomposites. ACS Nano (2010) 0.90
Cetuximab inhibits oral squamous cell carcinoma invasion and metastasis via degradation of epidermal growth factor receptor. J Oral Pathol Med (2013) 0.89
Expression of free fatty acid receptor GPR40 in the central nervous system of adult monkeys. Neurosci Res (2007) 0.89
Tissue angiotensin II in the regulation of inflammatory and fibrogenic components of repair in the rat heart. J Lab Clin Med (2004) 0.88
Autoradiography with positron emitting isotopes in positron emission tomography tracer discovery. Mol Imaging Biol (2003) 0.88
Induction of HIV-1-specific immunity after vaccination with apoptotic HIV-1/murine leukemia virus-infected cells. J Immunol (2002) 0.88
The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors. Oncotarget (2014) 0.87
Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with 11C. Nat Protoc (2006) 0.87
Self-retracting motion of graphite microflakes. Phys Rev Lett (2008) 0.87
Changes in Regional Cerebral Oxidative Metabolism Induced by Tactile Learning and Recognition in Man. Eur J Neurosci (1989) 0.87
The direct synthesis of hydrogen peroxide using platinum-promoted gold-palladium catalysts. Angew Chem Int Ed Engl (2014) 0.86
Brief Report: alterations in cerebral blood flow as assessed by PET/CT in adults with autism spectrum disorder with normal IQ. J Autism Dev Disord (2012) 0.86
Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo. J Ethnopharmacol (2013) 0.86
Novel development-related alternative splices in human testis identified by cDNA microarrays. J Androl (2005) 0.86
Nonlinear dielectric thin films for high-power electric storage with energy density comparable with electrochemical supercapacitors. IEEE Trans Ultrason Ferroelectr Freq Control (2011) 0.86
Nitric oxide fumigation stimulates flavonoid and phenolic accumulation and enhances antioxidant activity of mushroom. Food Chem (2012) 0.86
Calpain inhibition attenuates right ventricular contractile dysfunction after acute pressure overload. J Mol Cell Cardiol (2007) 0.86
The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. J Biol Chem (2002) 0.86
Loss of the p21(Cip1/Waf1) cyclin kinase inhibitor results in propagation of horizontally transferred DNA. Cancer Res (2002) 0.86
L-3-n-butylphthalide reduces tau phosphorylation and improves cognitive deficits in AβPP/PS1-Alzheimer's transgenic mice. J Alzheimers Dis (2012) 0.86
Overexpression of Wnt11 promotes chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in synergism with TGF-β. Mol Cell Biochem (2014) 0.85
Monodispersed mesoporous Li4Ti5O12 submicrospheres as anode materials for lithium-ion batteries: morphology and electrochemical performances. Nanoscale (2014) 0.85
Calpain inhibition preserves talin and attenuates right heart failure in acute pulmonary hypertension. Am J Respir Cell Mol Biol (2012) 0.85
Increased risk of acute myocardial infarction and stroke during hemorrhagic fever with renal syndrome: a self-controlled case series study. Circulation (2014) 0.85
Somatosensory Discrimination of Shape: Tactile Exploration and Cerebral Activation. Eur J Neurosci (1991) 0.85
Aqueous-processable noncovalent chemically converted graphene-quantum dot composites for flexible and transparent optoelectronic films. Adv Mater (2010) 0.85