Intravenous mesenchymal stem cell therapy for traumatic brain injury.

PubWeight™: 1.51‹?› | Rank: Top 4%

🔗 View Article (PMC 2889620)

Published in J Neurosurg on June 01, 2009

Authors

Matthew T Harting1, Fernando Jimenez, Hasan Xue, Uwe M Fischer, James Baumgartner, Pramod K Dash, Charles S Cox

Author Affiliations

1: Departments of Pediatric Surgery, University of Texas Medical School at Houston, Texas, USA.

Articles citing this

Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. Proc Natl Acad Sci U S A (2010) 2.27

Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis (2009) 1.61

Clinical imaging in regenerative medicine. Nat Biotechnol (2014) 1.43

Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: preserving the blood brain barrier via an interaction with splenocytes. Exp Neurol (2010) 1.42

Biodistribution of neural stem cells after intravascular therapy for hypoxic-ischemia. Stroke (2010) 1.37

Toward brain tumor gene therapy using multipotent mesenchymal stromal cell vectors. Mol Ther (2010) 1.18

Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One (2011) 1.10

Intra-arterial injection of neural stem cells using a microneedle technique does not cause microembolic strokes. J Cereb Blood Flow Metab (2010) 1.09

Enhanced homing permeability and retention of bone marrow stromal cells by noninvasive pulsed focused ultrasound. Stem Cells (2012) 1.00

Bone marrow stromal cells produce long-term pain relief in rat models of persistent pain. Stem Cells (2011) 0.99

Mesenchymal stem cells and acute lung injury. Crit Care Clin (2011) 0.98

Quantitative Magnetic Particle Imaging Monitors the Transplantation, Biodistribution, and Clearance of Stem Cells In Vivo. Theranostics (2016) 0.98

Mesenchymal stem cells for treatment of CNS injury. Curr Neuropharmacol (2010) 0.97

Cell-based therapy for acute organ injury: preclinical evidence and ongoing clinical trials using mesenchymal stem cells. Anesthesiology (2014) 0.94

Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis. PLoS One (2012) 0.92

Stem cells in neuroinjury and neurodegenerative disorders: challenges and future neurotherapeutic prospects. Neural Regen Res (2014) 0.91

Multimodal in vivo imaging reveals limited allograft survival, intrapulmonary cell trapping and minimal evidence for ischemia-directed BMSC homing. BMC Biotechnol (2012) 0.89

Tracking intravenous adipose-derived mesenchymal stem cells in a model of elastase-induced emphysema. Tuberc Respir Dis (Seoul) (2014) 0.86

Intraarterial transplantation of human umbilical cord blood mononuclear cells is more efficacious and safer compared with umbilical cord mesenchymal stromal cells in a rodent stroke model. Stem Cell Res Ther (2014) 0.85

Systematic review and meta-analysis of efficacy of mesenchymal stem cells on locomotor recovery in animal models of traumatic brain injury. Stem Cell Res Ther (2015) 0.83

Pulsed focused ultrasound pretreatment improves mesenchymal stromal cell efficacy in preventing and rescuing established acute kidney injury in mice. Stem Cells (2015) 0.83

Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor. J Ovarian Res (2010) 0.83

Progenitor cells as remote "bioreactors": neuroprotection via modulation of the systemic inflammatory response. World J Stem Cells (2011) 0.83

Cyclooxygenase-2 or tumor necrosis factor-α inhibitors attenuate the mechanotransductive effects of pulsed focused ultrasound to suppress mesenchymal stromal cell homing to healthy and dystrophic muscle. Stem Cells (2015) 0.82

Human Bone Marrow Derived Mesenchymal Stem Cells Regulate Leukocyte-Endothelial Interactions and Activation of Transcription Factor NF-Kappa B. J Tissue Sci Eng (2011) 0.82

Intravenous transplantation of bone marrow mesenchymal stem cells promotes neural regeneration after traumatic brain injury. Neural Regen Res (2014) 0.81

Cell-based therapy for traumatic brain injury. Br J Anaesth (2015) 0.80

Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat. PLoS One (2015) 0.79

Immunotherapeutic organoids: a new approach to cancer treatment. Biomatter (2013) 0.79

Traumatic Brain Injury in the Elderly: Is it as Bad as we Think? Curr Transl Geriatr Exp Gerontol Rep (2012) 0.79

Alzheimer's Disease: Mechanism and Approach to Cell Therapy. Int J Mol Sci (2015) 0.79

Development and application of neural stem cells for treating various human neurological diseases in animal models. Lab Anim Res (2013) 0.78

Mesenchymal Stromal Cell Dependent Regression of Pulmonary Metastasis from Ewing's. Front Pediatr (2014) 0.78

Clinical translation of stem cell therapy in traumatic brain injury: the potential of encapsulated mesenchymal cell biodelivery of glucagon-like peptide-1. Dialogues Clin Neurosci (2011) 0.78

Improving the therapeutic efficacy of mesenchymal stromal cells to restore perfusion in critical limb ischemia through pulsed focused ultrasound. Sci Rep (2017) 0.77

Effects of diagnostic ultrasound-targeted microbubble destruction on the homing ability of bone marrow stromal cells to the kidney parenchyma. Eur Radiol (2015) 0.77

Mesenchymal Stem Cells Reversed Morphine Tolerance and Opioid-induced Hyperalgesia. Sci Rep (2016) 0.77

Progenitor/stem cell transplantation for repair of myocardial infarction: Hype or hope? Ann Palliat Med (2012) 0.77

The preclinical discovery of amyotrophic lateral sclerosis drugs. Expert Opin Drug Discov (2011) 0.76

Increased Understanding of Stem Cell Behavior in Neurodegenerative and Neuromuscular Disorders by Use of Noninvasive Cell Imaging. Stem Cells Int (2016) 0.76

Treatment of Severe Adult Traumatic Brain Injury Using Bone Marrow Mononuclear Cells. Stem Cells (2016) 0.76

Allogeneic guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis. Stem Cell Res Ther (2015) 0.76

Regulation of S1P receptors and sphingosine kinases expression in acute pulmonary endothelial cell injury. PeerJ (2016) 0.75

Enhanced neuroprotective efficacy of bone marrow mesenchymal stem cells co-overexpressing BDNF and VEGF in a rat model of cardiac arrest-induced global cerebral ischemia. Cell Death Dis (2017) 0.75

Calcitonin gene-related peptide is a key factor in the homing of transplanted human MSCs to sites of spinal cord injury. Sci Rep (2016) 0.75

Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats. Yonsei Med J (2017) 0.75

Safety of Intraperitoneal Injection of Adipose Tissue-Derived Autologous Mesenchymal Stem Cells in Cats. J Vet Intern Med (2015) 0.75

Neural differentiation of mesenchymal stem cells influences their chemotactic responses to stromal cell-derived factor-1α. Cell Mol Neurobiol (2014) 0.75

Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture. Lab Chip (2017) 0.75

Tissue Engineering to Repair Diaphragmatic Defect in a Rat Model. Stem Cells Int (2017) 0.75

Articles cited by this

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med (2000) 11.35

Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med (1999) 9.73

Little evidence for developmental plasticity of adult hematopoietic stem cells. Science (2002) 9.63

Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation (2003) 5.34

Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation (2003) 5.20

Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol (2000) 3.94

Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med (2006) 3.81

A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J (2006) 3.43

Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science (2002) 3.18

Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol (2007) 2.88

Stem cell transplantation: the lung barrier. Transplant Proc (2007) 2.76

Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. Circulation (2004) 2.51

Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant (1995) 2.35

Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow. FASEB J (2004) 2.30

Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training. Proc Natl Acad Sci U S A (1997) 2.23

Controlled cortical impact: a new experimental brain injury model. J Neurotrauma (1988) 2.19

Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells. Neurosurgery (2003) 2.16

Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury. J Neurotrauma (2004) 1.87

Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells. Neurosurgery (2001) 1.87

Motor and cognitive function evaluation following experimental traumatic brain injury. Neurosci Biobehav Rev (2004) 1.80

Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science (2004) 1.75

Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome. Neuroreport (2001) 1.70

Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain. Neurosurgery (2004) 1.68

Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. J Hematother Stem Cell Res (2003) 1.66

Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions. Exp Brain Res (1985) 1.59

Potential of stem-cell-based therapies for heart disease. Nature (2006) 1.56

Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of caution. Stem Cells (2005) 1.51

Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc Natl Acad Sci U S A (2006) 1.50

Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells. Stem Cells (2007) 1.35

Mesenchymal stem cells derived from peripheral blood protects against ischemia. J Neurotrauma (2007) 1.33

Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats. Neurosurgery (2005) 1.27

Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats. J Neurosurg (2006) 1.27

Intravenous delivery of autologous mesenchymal stem cells limits infarct size and improves left ventricular function in the infarcted porcine heart. Stem Cells Dev (2007) 1.25

Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expression. Stem Cells Dev (2006) 1.15

Multipotent adult progenitor cell isolation and culture procedures. Exp Hematol (2006) 1.15

Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury. J Med Invest (2006) 1.11

Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene. Biochem Biophys Res Commun (2005) 1.10

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells. Blood (2006) 1.08

Murine bone marrow stromal progenitor cells elicit an in vivo cellular and humoral alloimmune response. Biol Blood Marrow Transplant (2007) 1.07

Human umbilical cord blood cells differentiate into muscle in sjl muscular dystrophy mice. Stem Cells (2004) 1.00

Comment on "Little evidence for developmental plasticity of adult hematopoietic stem cells". Science (2003) 0.99

Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo". Science (2003) 0.96

Stem cell therapy for human liver cirrhosis: a cautious analysis of the results. Stem Cells (2007) 0.96

Differential expression of neural cell adhesion molecule (NCAM) during osteogenesis and secondary chondrogenesis in the embryonic chick. Int J Dev Biol (1995) 0.95

Stem cell therapy improves myocardial perfusion and cardiac synchronicity: new application for echocardiography. J Am Soc Echocardiogr (2007) 0.93

Elusive mechanisms of "stem cell"-mediated repair of cerebral damage. Exp Neurol (2006) 0.92

Intravenous mononuclear marrow cells reverse neuropathic pain from experimental mononeuropathy. Anesth Analg (2007) 0.88

Hematopoiesis from human embryonic stem cells: overcoming the immune barrier in stem cell therapies. Stem Cells (2005) 0.83

Articles by these authors

Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev (2009) 3.43

Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury. J Neurosci (2007) 1.82

Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab (2009) 1.80

Human traumatic brain injury alters plasma microRNA levels. J Neurotrauma (2010) 1.70

A role for prefrontal cortex in memory storage for trace fear conditioning. J Neurosci (2004) 1.69

LIFEBRIDGE: a portable, modular, rapidly available "plug-and-play" mechanical circulatory support system. Ann Thorac Surg (2005) 1.66

Intravenous autologous bone marrow mononuclear cells for ischemic stroke. Ann Neurol (2011) 1.64

Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke (2007) 1.61

Acute, regional inflammatory response after traumatic brain injury: Implications for cellular therapy. Surgery (2008) 1.59

Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci Lett (2005) 1.57

A role for the prefrontal cortex in recall of recent and remote memories. Neuroreport (2006) 1.54

Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma. J Pediatr Surg (2006) 1.50

Right-sided vagus nerve stimulation as a treatment for refractory epilepsy in humans. Epilepsia (2005) 1.49

Traumatic brain injury alters expression of hippocampal microRNAs: potential regulators of multiple pathophysiological processes. J Neurosci Res (2009) 1.48

Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/β-catenin signaling. Stem Cells Dev (2010) 1.44

Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: preserving the blood brain barrier via an interaction with splenocytes. Exp Neurol (2010) 1.42

Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury. J Neurosci Res (2005) 1.36

Arrested development and disrupted callosal microstructure following pediatric traumatic brain injury: relation to neurobehavioral outcomes. Neuroimage (2008) 1.33

Late intellectual and academic outcomes following traumatic brain injury sustained during early childhood. J Neurosurg (2006) 1.32

High-density microarray analysis of hippocampal gene expression following experimental brain injury. J Neurosci Res (2002) 1.32

Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury. J Neuroinflammation (2010) 1.23

Biomarkers for the diagnosis and prognosis of mild traumatic brain injury/concussion. J Neurotrauma (2013) 1.22

A role for prefrontal calcium-sensitive protein phosphatase and kinase activities in working memory. Learn Mem (2005) 1.17

Mechanics of the left ventricular myocardial interstitium: effects of acute and chronic myocardial edema. Am J Physiol Heart Circ Physiol (2008) 1.16

Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population. J Neuroinflammation (2012) 1.15

Identification of serum biomarkers in brain-injured adults: potential for predicting elevated intracranial pressure. J Neurotrauma (2008) 1.14

Autologous bone marrow mononuclear cell therapy for severe traumatic brain injury in children. Neurosurgery (2011) 1.14

Subacute neural stem cell therapy for traumatic brain injury. J Surg Res (2008) 1.14

Altered expression of miRNA-21 and its targets in the hippocampus after traumatic brain injury. J Neurosci Res (2010) 1.12

Age as a prognostic factor for patients with osteosarcoma: an analysis of 438 patients. J Cancer Res Clin Oncol (2009) 1.10

Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production. Stem Cells Dev (2010) 1.10

Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One (2011) 1.10

Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury. Sci Transl Med (2012) 1.09

Intra-medial prefrontal administration of SCH-23390 attenuates ERK phosphorylation and long-term memory for trace fear conditioning in rats. Neurobiol Learn Mem (2004) 1.09

Reversal of brain injury-induced prefrontal glutamic acid decarboxylase expression and working memory deficits by D1 receptor antagonism. J Neurosci (2006) 1.08

Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats. Brain Res (2003) 1.08

The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex. Hum Mol Genet (2012) 1.06

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex. Neurobiol Dis (2012) 1.05

Progenitor cell therapies for traumatic brain injury: barriers and opportunities in translation. Dis Model Mech (2009) 1.03

Intestinal edema decreases intestinal contractile activity via decreased myosin light chain phosphorylation. Crit Care Med (2006) 1.03

Resuscitation-induced intestinal edema decreases the stiffness and residual stress of the intestine. Shock (2005) 1.03

Hypertonic saline reverses stiffness in a Sprague-Dawley rat model of acute intestinal edema, leading to improved intestinal function. Crit Care Med (2007) 1.03

Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: implications for prefrontal dysfunction. J Neurotrauma (2006) 1.03

Resuscitation-induced gut edema and intestinal dysfunction. J Trauma (2005) 1.01

Acute ethanol intake attenuates inflammatory cytokines after brain injury in rats: a possible role for corticosterone. J Neurotrauma (2002) 1.01

Biomarkers in the clinical diagnosis and management of traumatic brain injury. Mol Diagn Ther (2008) 1.00

Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury. Shock (2005) 0.99

First year changes of myocardial lymphatic endothelial markers in heart transplant recipients. Eur J Cardiothorac Surg (2006) 0.98

Edema-induced intestinal dysfunction is mediated by STAT3 activation. Shock (2007) 0.97

Genetic networks controlling retinal injury. Mol Vis (2005) 0.97

Analysis of functional pathways altered after mild traumatic brain injury. J Neurotrauma (2013) 0.96

Challenges in the development of rodent models of mild traumatic brain injury. J Neurotrauma (2013) 0.96

Admission rapid thrombelastography delivers real-time "actionable" data in pediatric trauma. J Pediatr Surg (2013) 0.96

Human mesenchymal stem cells inhibit endothelial proliferation and angiogenesis via cell-cell contact through modulation of the VE-Cadherin/β-catenin signaling pathway. Stem Cells Dev (2012) 0.96

Effects of primary and secondary intra-abdominal hypertension on mesenteric lymph flow: implications for the abdominal compartment syndrome. Shock (2005) 0.96

Hypertonic saline resuscitation prevents hydrostatically induced intestinal edema and ileus. Crit Care Med (2006) 0.96

Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution. J Cereb Blood Flow Metab (2006) 0.96

Behavioral and histopathological alterations resulting from mild fluid percussion injury. J Neurotrauma (2013) 0.96

Effect of needle diameter and flow rate on rat and human mesenchymal stromal cell characterization and viability. Tissue Eng Part C Methods (2010) 0.95

Intravenous multipotent adult progenitor cell therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury. Stem Cells Transl Med (2013) 0.95

Immunomagnetic enrichment and flow cytometric characterization of mouse microglia. J Neurosci Methods (2013) 0.94

A clinical comparison of penetrating and blunt traumatic brain injuries. Brain Inj (2012) 0.94

A novel strategy to activate cytoprotective genes in the injured brain. Biochem Biophys Res Commun (2011) 0.94

Distinct prefrontal molecular mechanisms for information storage lasting seconds versus minutes. Learn Mem (2005) 0.94

Bone marrow-derived stromal cell therapy for traumatic brain injury is neuroprotective via stimulation of non-neurologic organ systems. Surgery (2012) 0.94

Component separation for complex congenital abdominal wall defects: not just for adults anymore. J Pediatr Surg (2013) 0.94

Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats. Endocrinology (2008) 0.93

Nitrotyrosine and 8-isoprostane formation indicate free radical-mediated injury in hearts of patients subjected to cardioplegia. J Thorac Cardiovasc Surg (2003) 0.93

Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCF(β-TRCP) in neuroblastoma cells. Cancer (2011) 0.93

Human mild traumatic brain injury decreases circulating branched-chain amino acids and their metabolite levels. J Neurotrauma (2013) 0.92

Nonclassical mechanisms of progesterone action in the brain: II. Role of calmodulin-dependent protein kinase II in progesterone-mediated signaling in the hypothalamus of female rats. Endocrinology (2008) 0.92

Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism. J Neurotrauma (2003) 0.92

Measurement of intestinal edema using an impedance analyzer circuit. J Surg Res (2006) 0.90

Cell therapies for traumatic brain injury. Neurosurg Focus (2008) 0.89

Acutely increased cyclophilin a expression after brain injury: a role in blood-brain barrier function and tissue preservation. J Neurosci Res (2007) 0.89

Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning. Learn Mem (2013) 0.89

Patients with impending abdominal compartment syndrome do not respond to early volume loading. Am J Surg (2003) 0.89

Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat. J Trauma (2011) 0.89