Human traumatic brain injury alters plasma microRNA levels.

PubWeight™: 1.70‹?› | Rank: Top 3%

🔗 View Article (PMID 20883153)

Published in J Neurotrauma on November 23, 2010

Authors

John B Redell1, Anthony N Moore, Norman H Ward, Georgene W Hergenroeder, Pramod K Dash

Author Affiliations

1: Department of Neurobiology and Anatomy, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

Associated clinical trials:

Proteomics of Brain Trauma-associated Elevated Intracranial Pressure (ICP) (Proteomics) | NCT00178659

Articles citing this

Characterization of extracellular circulating microRNA. Nucleic Acids Res (2011) 6.24

A serum circulating miRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer. EMBO Mol Med (2011) 1.83

The Impact of Hemolysis on Cell-Free microRNA Biomarkers. Front Genet (2013) 1.54

Serum circulating microRNA profiling for identification of potential type 2 diabetes and obesity biomarkers. PLoS One (2013) 1.24

The emerging roles of microRNAs in CNS injuries. Nat Rev Neurol (2013) 1.18

Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans. Int Rev Neurobiol (2014) 1.17

Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection. BMC Infect Dis (2012) 1.13

A plasma microRNA signature of acute lentiviral infection: biomarkers of central nervous system disease. AIDS (2011) 1.10

Serum microRNA expression profile distinguishes enterovirus 71 and coxsackievirus 16 infections in patients with hand-foot-and-mouth disease. PLoS One (2011) 1.08

MicroRNA and epilepsy: profiling, functions and potential clinical applications. Curr Opin Neurol (2014) 1.08

MicroRNAs: Meta-controllers of gene expression in synaptic activity emerge as genetic and diagnostic markers of human disease. Pharmacol Ther (2011) 1.03

MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury. J Neurotrauma (2012) 1.02

MicroRNAs as active players in the pathogenesis of multiple sclerosis. Int J Mol Sci (2012) 0.96

Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders. Front Mol Neurosci (2014) 0.96

Comprehensive characterization of serum microRNA profile in response to the emerging avian influenza A (H7N9) virus infection in humans. Viruses (2014) 0.94

Understanding Alcoholism Through microRNA Signatures in Brains of Human Alcoholics. Front Genet (2012) 0.94

Systems biology approaches for discovering biomarkers for traumatic brain injury. J Neurotrauma (2013) 0.92

Circulating microRNAs serve as novel biological markers for intracranial aneurysms. J Am Heart Assoc (2014) 0.91

Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol (2015) 0.91

MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. Front Cell Neurosci (2014) 0.91

miR-21 improves the neurological outcome after traumatic brain injury in rats. Sci Rep (2014) 0.91

All's well that transcribes well: non-coding RNAs and post-stroke brain damage. Neurochem Int (2013) 0.88

Maternal and neonatal plasma microRNA biomarkers for fetal alcohol exposure in an ovine model. Alcohol Clin Exp Res (2014) 0.87

Investigational agents for treatment of traumatic brain injury. Expert Opin Investig Drugs (2015) 0.84

What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment. Int J Mol Sci (2015) 0.83

Exosome platform for diagnosis and monitoring of traumatic brain injury. Philos Trans R Soc Lond B Biol Sci (2014) 0.83

Epigenetic changes following traumatic brain injury and their implications for outcome, recovery and therapy. Neurosci Lett (2016) 0.83

Circulating miR-765 and miR-149: potential noninvasive diagnostic biomarkers for geriatric coronary artery disease patients. Biomed Res Int (2015) 0.82

Current status of fluid biomarkers in mild traumatic brain injury. Exp Neurol (2015) 0.82

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.81

Identification of serum microRNA signatures for diagnosis of mild traumatic brain injury in a closed head injury model. PLoS One (2014) 0.81

The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review. Burns Trauma (2016) 0.81

The diagnostic value of circulating microRNAs for middle-aged (40-60-year-old) coronary artery disease patients. Clinics (Sao Paulo) (2015) 0.80

Blood biomarkers for brain injury: What are we measuring? Neurosci Biobehav Rev (2016) 0.80

microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury. Am J Transl Res (2016) 0.79

MiR-630 Inhibits Endothelial-Mesenchymal Transition by Targeting Slug in Traumatic Heterotopic Ossification. Sci Rep (2016) 0.79

Detection and quantification of microRNA in cerebral microdialysate. J Transl Med (2015) 0.78

Rapid release of tissue enzymes into blood after blast exposure: potential use as biological dosimeters. PLoS One (2012) 0.78

Fluid biomarkers for mild traumatic brain injury and related conditions. Nat Rev Neurol (2016) 0.77

Epilepsy related to traumatic brain injury. Neurotherapeutics (2014) 0.77

Altered regulation of protein kinase a activity in the medial prefrontal cortex of normal and brain-injured animals actively engaged in a working memory task. J Neurotrauma (2014) 0.77

Non-coding RNAs and neuroprotection after acute CNS injuries. Neurochem Int (2017) 0.76

Behavioral, blood, and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury. Sci Rep (2016) 0.75

Analysis of Serum microRNA Expression Profiles and Comparison with Small Intestinal microRNA Expression Profiles in Weaned Piglets. PLoS One (2016) 0.75

A New Tool for in vivo Manipulation of Brain microRNA Levels: The Work of Smalheiser et al. (2014). Front Psychiatry (2015) 0.75

Blood Biomarkers for Evaluation of Perinatal Encephalopathy. Front Pharmacol (2016) 0.75

Detection of hypoxia markers in the cerebellum after a traumatic frontal cortex injury: a human postmortem gene expression analysis. Int J Legal Med (2014) 0.75

Aquaporin-4: A Potential Therapeutic Target for Cerebral Edema. Int J Mol Sci (2016) 0.75

MicroRNAs in Experimental Models of Movement Disorders. J Mov Disord (2011) 0.75

Circulating microRNAs and sudden cardiac arrest outcomes. Resuscitation (2016) 0.75

Epigenetic Modifications of Major Depressive Disorder. Int J Mol Sci (2016) 0.75

A Panel of Serum MiRNA Biomarkers for the Diagnosis of Severe to Mild Traumatic Brain Injury in Humans. Sci Rep (2016) 0.75

Voluntary exercise prior to traumatic brain injury alters miRNA expression in the injured mouse cerebral cortex. Braz J Med Biol Res (2015) 0.75

MicroRNA Changes in Cerebrospinal Fluid After Subarachnoid Hemorrhage. Stroke (2017) 0.75

Articles by these authors

Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury. J Neurosci (2007) 1.82

A role for prefrontal cortex in memory storage for trace fear conditioning. J Neurosci (2004) 1.69

Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke (2007) 1.61

Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway. J Neurosci (2006) 1.59

Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci Lett (2005) 1.57

A role for the prefrontal cortex in recall of recent and remote memories. Neuroreport (2006) 1.54

Intravenous mesenchymal stem cell therapy for traumatic brain injury. J Neurosurg (2009) 1.51

Traumatic brain injury alters expression of hippocampal microRNAs: potential regulators of multiple pathophysiological processes. J Neurosci Res (2009) 1.48

Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/β-catenin signaling. Stem Cells Dev (2010) 1.44

Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: preserving the blood brain barrier via an interaction with splenocytes. Exp Neurol (2010) 1.42

Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury. J Neurosci Res (2005) 1.36

Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats. PLoS One (2010) 1.36

High-density microarray analysis of hippocampal gene expression following experimental brain injury. J Neurosci Res (2002) 1.32

Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury. J Neuroinflammation (2010) 1.23

Biomarkers for the diagnosis and prognosis of mild traumatic brain injury/concussion. J Neurotrauma (2013) 1.22

Biomarkers for the diagnosis, prognosis, and evaluation of treatment efficacy for traumatic brain injury. Neurotherapeutics (2010) 1.17

A role for prefrontal calcium-sensitive protein phosphatase and kinase activities in working memory. Learn Mem (2005) 1.17

Identification of serum biomarkers in brain-injured adults: potential for predicting elevated intracranial pressure. J Neurotrauma (2008) 1.14

Altered expression of miRNA-21 and its targets in the hippocampus after traumatic brain injury. J Neurosci Res (2010) 1.12

Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One (2011) 1.10

Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production. Stem Cells Dev (2010) 1.10

Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury. Sci Transl Med (2012) 1.09

Intra-medial prefrontal administration of SCH-23390 attenuates ERK phosphorylation and long-term memory for trace fear conditioning in rats. Neurobiol Learn Mem (2004) 1.09

Reversal of brain injury-induced prefrontal glutamic acid decarboxylase expression and working memory deficits by D1 receptor antagonism. J Neurosci (2006) 1.08

Molecular activity underlying working memory. Learn Mem (2007) 1.08

Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats. Brain Res (2003) 1.08

The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex. Hum Mol Genet (2012) 1.06

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex. Neurobiol Dis (2012) 1.05

A role for hippocampal Rho-ROCK pathway in long-term spatial memory. Biochem Biophys Res Commun (2004) 1.04

Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: implications for prefrontal dysfunction. J Neurotrauma (2006) 1.03

Sulforaphane improves cognitive function administered following traumatic brain injury. Neurosci Lett (2009) 1.02

Acute ethanol intake attenuates inflammatory cytokines after brain injury in rats: a possible role for corticosterone. J Neurotrauma (2002) 1.01

A molecular description of brain trauma pathophysiology using microarray technology: an overview. Neurochem Res (2004) 1.01

Biomarkers in the clinical diagnosis and management of traumatic brain injury. Mol Diagn Ther (2008) 1.00

Post-trauma administration of caffeine plus ethanol reduces contusion volume and improves working memory in rats. J Neurotrauma (2004) 0.98

Genetic networks controlling retinal injury. Mol Vis (2005) 0.97

Analysis of functional pathways altered after mild traumatic brain injury. J Neurotrauma (2013) 0.96

Challenges in the development of rodent models of mild traumatic brain injury. J Neurotrauma (2013) 0.96

Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution. J Cereb Blood Flow Metab (2006) 0.96

Behavioral and histopathological alterations resulting from mild fluid percussion injury. J Neurotrauma (2013) 0.96

Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome. PLoS One (2011) 0.95

ZIP4 is a novel molecular marker for glioma. Neuro Oncol (2013) 0.95

A clinical comparison of penetrating and blunt traumatic brain injuries. Brain Inj (2012) 0.94

A novel strategy to activate cytoprotective genes in the injured brain. Biochem Biophys Res Commun (2011) 0.94

Distinct prefrontal molecular mechanisms for information storage lasting seconds versus minutes. Learn Mem (2005) 0.94

Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats. Endocrinology (2008) 0.93

Human mild traumatic brain injury decreases circulating branched-chain amino acids and their metabolite levels. J Neurotrauma (2013) 0.92

Nonclassical mechanisms of progesterone action in the brain: II. Role of calmodulin-dependent protein kinase II in progesterone-mediated signaling in the hypothalamus of female rats. Endocrinology (2008) 0.92

Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism. J Neurotrauma (2003) 0.92

Acutely increased cyclophilin a expression after brain injury: a role in blood-brain barrier function and tissue preservation. J Neurosci Res (2007) 0.89

Sequestration of serum response factor in the hippocampus impairs long-term spatial memory. J Neurochem (2005) 0.89

Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning. Learn Mem (2013) 0.89

Inhibition of hippocampal protein synthesis following recall disrupts expression of episodic-like memory in trace conditioning. Hippocampus (2005) 0.88

Inhibition of prefrontal protein synthesis following recall does not disrupt memory for trace fear conditioning. BMC Neurosci (2006) 0.88

Expression of the prodynorphin gene after experimental brain injury and its role in behavioral dysfunction. Exp Biol Med (Maywood) (2003) 0.88

Enhancement of tyrosine hydroxylase phosphorylation and activity by glial cell line-derived neurotrophic factor. J Biol Chem (2003) 0.88

Autologous bone marrow mononuclear cells therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury. J Trauma Acute Care Surg (2013) 0.87

Repeated mild closed head injury impairs short-term visuospatial memory and complex learning. J Neurotrauma (2013) 0.85

Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury. J Neurotrauma (2012) 0.85

Extracellular signal-regulated kinase activity in the entorhinal cortex is necessary for long-term spatial memory. Learn Mem (2002) 0.84

Inhibition of conditioned stimulus pathway phosphoprotein 24 expression blocks the development of intermediate-term memory in Hermissenda. J Neurosci (2003) 0.82

CYP4Fs expression in rat brain correlates with changes in LTB4 levels after traumatic brain injury. J Neurotrauma (2008) 0.82

A cell-permeable phospholipase Cgamma1-binding peptide transduces neurons and impairs long-term spatial memory. Learn Mem (2004) 0.82

Venous thromboembolism prophylaxis in emergency department admissions. J Hosp Med (2007) 0.82

Intra-hippocampal administration of the VEGF receptor blocker PTK787/ZK222584 impairs long-term memory. Brain Res (2008) 0.82

Traumatic brain injury stimulates hippocampal catechol-O-methyl transferase expression in microglia. Neurosci Lett (2006) 0.82

Rho/ROCK and Cdk5 effects on phosphorylation of a beta-thymosin repeat protein in Hermissenda. Biochem Biophys Res Commun (2004) 0.80

Human traumatic brain injury alters circulating L-arginine and its metabolite levels: possible link to cerebral blood flow, extracellular matrix remodeling, and energy status. J Neurotrauma (2011) 0.80

Heparin-platelet factor 4 antibodies in intensive care patients: an observational seroprevalence study. J Thromb Thrombolysis (2010) 0.80

Blockade of gamma-secretase activity within the hippocampus enhances long-term memory. Biochem Biophys Res Commun (2005) 0.79

Intrahippocampal wortmannin infusion enhances long-term spatial and contextual memories. Learn Mem (2002) 0.79