Published in FEBS Lett on February 06, 2009
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Predicting extensively drug-resistant Mycobacterium tuberculosis phenotypes with genetic mutations. J Clin Microbiol (2013) 1.66
Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. Nat Chem Biol (2011) 1.62
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The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin. Chem Biol (2004) 1.59
Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells. J Biol Chem (2006) 1.48
Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis. Cancer Res (2008) 1.45
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. Oncogene (2003) 1.38
Analysis of kimchi microflora using denaturing gradient gel electrophoresis. Int J Food Microbiol (2005) 1.33
Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone. Proc Natl Acad Sci U S A (2008) 1.28
Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors. Radiat Res (2004) 1.26
Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Chem Biol (2006) 1.25
Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death. Exp Mol Med (2007) 1.24
Selection strategies for the establishment of recombinant Chinese hamster ovary cell line with dihydrofolate reductase-mediated gene amplification. Appl Microbiol Biotechnol (2005) 1.22
Influence of age and regional differences on skin elasticity as measured by the Cutometer. Skin Res Technol (2008) 1.22
The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria. FEBS Lett (2004) 1.20
Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition. J Biol Chem (2008) 1.20
Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells. Oncotarget (2014) 1.20
NDRG2 suppresses cell proliferation through down-regulation of AP-1 activity in human colon carcinoma cells. Int J Cancer (2009) 1.18
Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci (2008) 1.18
TrkC plays an essential role in breast tumor growth and metastasis. Carcinogenesis (2010) 1.18
Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin. EMBO J (2006) 1.18
Primary gastric choriocarcinoma: two case reports and review of the literatures. Cancer Res Treat (2008) 1.17
DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma. Biochem Biophys Res Commun (2007) 1.16
Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress. Biochem Pharmacol (2011) 1.14
Evaluation of annexin II as a potential serum marker for hepatocellular carcinoma using a developed sandwich ELISA method. Int J Mol Med (2009) 1.13
Attenuated DNA damage repair by trichostatin A through BRCA1 suppression. Radiat Res (2007) 1.13
Enhanced expression of SOS1 is detected in prostate cancer epithelial cells from African-American men. Int J Oncol (2009) 1.13
Synthesis of (+)-vinblastine and its analogues. Org Lett (2007) 1.12
Mononuclear nonheme ferric-peroxo complex in aldehyde deformylation. Chem Commun (Camb) (2005) 1.11
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I. Proc Natl Acad Sci U S A (2008) 1.10
Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster. J Biol Chem (2003) 1.10
Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp. Org Lett (2002) 1.10
Chemical genetic screening identifies a novel inhibitor of parallel alignment of cortical microtubules and cellulose microfibrils. Plant Cell Physiol (2007) 1.10
Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors. Bioorg Med Chem Lett (2005) 1.10
Up-regulation of Mac-2 binding protein by hTERT in gastric cancer. Int J Cancer (2007) 1.08
RECK negatively regulates matrix metalloproteinase-9 transcription. Cancer Res (2009) 1.08
HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling. Mol Cancer (2010) 1.08
Cloning, sequencing, and characterization of the pradimicin biosynthetic gene cluster of Actinomadura hibisca P157-2. J Microbiol Biotechnol (2007) 1.07
Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A. Int J Cancer (2003) 1.07
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli. J Ind Microbiol Biotechnol (2011) 1.06
ATM missense mutations are frequent in patients with breast cancer. Cancer Genet Cytogenet (2003) 1.06
SPR imaging of photo-cross-linked small-molecule arrays on gold. Anal Chem (2006) 1.06
Morphobase, an encyclopedic cell morphology database, and its use for drug target identification. Chem Biol (2012) 1.05
Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion. Biochem Biophys Res Commun (2003) 1.05
Apolipoprotein A-I induces IL-10 and PGE2 production in human monocytes and inhibits dendritic cell differentiation and maturation. Biochem Biophys Res Commun (2005) 1.04
PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis. Genome Biol (2014) 1.03
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus. Chembiochem (2009) 1.03
Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells. Cancer Lett (2005) 1.03
Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis. J Nat Prod (2009) 1.03
Heparanase as a molecular target of cancer chemotherapy. Cancer Sci (2004) 1.02
Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. J Bacteriol (2010) 1.02
UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy. Proc Natl Acad Sci U S A (2013) 1.01
ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma. Amino Acids (2010) 1.00
Dual function of a bee venom serine protease: prophenoloxidase-activating factor in arthropods and fibrin(ogen)olytic enzyme in mammals. PLoS One (2010) 1.00
Effect of Helicobacter pylori Eradication on Functional Dyspepsia. J Neurogastroenterol Motil (2013) 1.00
A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning. Biochem J (2002) 1.00
NF-kappaB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation. Carcinogenesis (2005) 0.99
Essential role of Cenexin1, but not Odf2, in ciliogenesis. Cell Cycle (2013) 0.99
ESM-1 regulates cell growth and metastatic process through activation of NF-κB in colorectal cancer. Cell Signal (2012) 0.99
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. Nat Chem Biol (2010) 0.98
Novel inhibitors of human histone deacetylase (HDAC) identified by QSAR modeling of known inhibitors, virtual screening, and experimental validation. J Chem Inf Model (2009) 0.98
Upregulation of the cysteine protease inhibitor, cystatin SN, contributes to cell proliferation and cathepsin inhibition in gastric cancer. Clin Chim Acta (2009) 0.98
Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays. Biochem Biophys Res Commun (2010) 0.98
Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions. Angew Chem Int Ed Engl (2003) 0.98
Diet-induced obesity leads to decreased hepatic iron storage in mice. Nutr Res (2011) 0.98
Secretion of heparanase protein is regulated by glycosylation in human tumor cell lines. J Biol Chem (2003) 0.98
Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer. J Cancer Res Clin Oncol (2008) 0.98
Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease. Exp Neurol (2012) 0.98
Osteoporosis regulation by salubrinal through eIF2α mediated differentiation of osteoclast and osteoblast. Cell Signal (2012) 0.97
Identification of endothelial cell-specific molecule-1 as a potential serum marker for colorectal cancer. Cancer Sci (2010) 0.97
A combination therapy with transarterial chemo-lipiodolization and systemic chemo-infusion for large extensive hepatocellular carcinoma invading portal vein in comparison with conservative management. Cancer Chemother Pharmacol (2006) 0.97
Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism. J Proteome Res (2011) 0.97
Biotransformation of the mycotoxin, zearalenone, to a non-estrogenic compound by a fungal strain of Clonostachys sp. Biosci Biotechnol Biochem (2002) 0.97
Genome-wide maps of mono- and di-nucleosomes of Aspergillus fumigatus. Bioinformatics (2009) 0.96
Protein tyrosine phosphatase 1B inhibitors from Morus root bark. Bioorg Med Chem Lett (2005) 0.96
In vitro plasma stability, permeability and solubility of mercaptoacetamide histone deacetylase inhibitors. Int J Pharm (2008) 0.96
Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance. Cancer Sci (2004) 0.96
Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer. Cancer (2010) 0.96
Antidiabetic effects of extracts from Psidium guajava. J Ethnopharmacol (2005) 0.96
A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5. Chem Biol (2003) 0.96
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis. J Biol Chem (2008) 0.96