Published in J Cell Sci on April 15, 2009
ClC-3 is an intracellular chloride/proton exchanger with large voltage-dependent nonlinear capacitance. ACS Chem Neurosci (2013) 1.05
The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci (2010) 0.99
Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation. J Biol Chem (2010) 0.91
Chloride channels of intracellular membranes. FEBS Lett (2010) 0.91
A pH-independent DNA nanodevice for quantifying chloride transport in organelles of living cells. Nat Nanotechnol (2015) 0.90
ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5. Pflugers Arch (2010) 0.87
ATP induces conformational changes in the carboxyl-terminal region of ClC-5. J Biol Chem (2010) 0.87
Gene trapping identifies chloride channel 4 as a novel inducer of colon cancer cell migration, invasion and metastases. Br J Cancer (2010) 0.78
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19
Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15
Broken barriers: a new take on sepsis pathogenesis. Sci Transl Med (2011) 2.01
Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles. Nature (2008) 1.89
Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner. J Biol Chem (2012) 1.80
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nat Biotechnol (2012) 1.73
CFTR directly mediates nucleotide-regulated glutathione flux. EMBO J (2003) 1.45
CO(2)-driven ocean acidification alters and weakens integrity of the calcareous tubes produced by the serpulid tubeworm, Hydroides elegans. PLoS One (2012) 1.31
Probing structure-function relationships and gating mechanisms in the CorA Mg2+ transport system. J Biol Chem (2008) 1.25
Evidence for a superoxide permeability pathway in endosomal membranes. Mol Cell Biol (2008) 1.21
A small-molecule modulator interacts directly with deltaPhe508-CFTR to modify its ATPase activity and conformational stability. Mol Pharmacol (2009) 1.21
The chloride channel ClC-4 contributes to endosomal acidification and trafficking. J Biol Chem (2003) 1.17
Structural basis for alginate secretion across the bacterial outer membrane. Proc Natl Acad Sci U S A (2011) 1.11
Cystic fibrosis transmembrane conductance regulator in human muscle: Dysfunction causes abnormal metabolic recovery in exercise. Ann Neurol (2010) 1.10
A chemical corrector modifies the channel function of F508del-CFTR. Mol Pharmacol (2010) 1.10
Surface charge: a key determinant of protein localization and function. Cancer Res (2010) 1.09
Dimeric cystic fibrosis transmembrane conductance regulator exists in the plasma membrane. Biochem J (2003) 1.08
The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer. Biochem J (2007) 1.03
A heteromeric complex of the two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) mediates ATPase activity. J Biol Chem (2004) 1.02
Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. Biochem J (2009) 1.02
Lysosomal pH and analysis of the counter ion pathways that support acidification. J Gen Physiol (2011) 1.01
Evidence for a functional interaction between the ClC-2 chloride channel and the retrograde motor dynein complex. J Biol Chem (2003) 0.98
The chloride channel ClC-4 co-localizes with cystic fibrosis transmembrane conductance regulator and may mediate chloride flux across the apical membrane of intestinal epithelia. J Biol Chem (2001) 0.97
Complete genome sequence of Klebsiella pneumoniae phage JD001. J Virol (2012) 0.97
The intact CFTR protein mediates ATPase rather than adenylate kinase activity. Biochem J (2008) 0.95
Nucleotides bind to the C-terminus of ClC-5. Biochem J (2006) 0.94
Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein. Methods Mol Med (2002) 0.94
Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons. J Neuroinflammation (2014) 0.93
Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant. J Biol Chem (2011) 0.93
Clinical efficacy of albendazole emulsion in treatment of 212 cases of liver cystic hydatidosis. Chin Med J (Engl) (2002) 0.92
Molecular basis for the chloride channel activity of cystic fibrosis transmembrane conductance regulator and the consequences of disease-causing mutations. Curr Top Dev Biol (2004) 0.90
Proton-dependent gating and proton uptake by Wzx support O-antigen-subunit antiport across the bacterial inner membrane. MBio (2013) 0.90
Functional Rescue of F508del-CFTR Using Small Molecule Correctors. Front Pharmacol (2012) 0.90
In vivo optical imaging of tumor and microvascular response to ionizing radiation. PLoS One (2012) 0.90
Cytological mechanism of pollen abortion resulting from allelic interaction of F1 pollen sterility locus in rice (Oryza sativa L.). Genetica (2006) 0.90
Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods. J Cyst Fibros (2004) 0.89
Molecular basis for the ATPase activity of CFTR. Arch Biochem Biophys (2008) 0.88
Synergistic suppression effect on tumor growth of hepatocellular carcinoma by combining oncolytic adenovirus carrying XAF1 with cisplatin. J Cancer Res Clin Oncol (2014) 0.87
ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5. Pflugers Arch (2010) 0.87
ATP induces conformational changes in the carboxyl-terminal region of ClC-5. J Biol Chem (2010) 0.87
Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy. Essays Biochem (2011) 0.86
In situ measurement of the electrical potential across the lysosomal membrane using FRET. Traffic (2011) 0.86
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. J Biol Chem (2013) 0.86
Zinc stabilization efficiency of aluminate spinel structure and its leaching behavior. Environ Sci Technol (2011) 0.85
Functional rescue of DeltaF508-CFTR by peptides designed to mimic sorting motifs. Chem Biol (2009) 0.85
Complete genome sequence of wide-host-range Staphylococcus aureus phage JD007. J Virol (2012) 0.85
Depiction of transplant renal vascular anatomy and complications: unenhanced MR angiography by using spatial labeling with multiple inversion pulses. Radiology (2014) 0.85
Phosphorylation-induced conformational changes of cystic fibrosis transmembrane conductance regulator monitored by attenuated total reflection-Fourier transform IR spectroscopy and fluorescence spectroscopy. J Biol Chem (2003) 0.84
The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation. Proteomics (2014) 0.83
ATP depletion inhibits the endocytosis of ClC-2. J Cell Physiol (2008) 0.83
Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells. Nanomedicine (2011) 0.83
Evaluation of the membrane-spanning domain of ClC-2. Biochem J (2006) 0.83
High performance bipolar resistive switching memory devices based on Zn2SnO4 nanowires. Nanoscale (2012) 0.83
How does the host-specialized aphid deal with food deficiency? Insect Sci (2014) 0.83
Polymorphism of A118G in μ-opioid receptor gene is associated with risk of esophageal squamous cell carcinoma in a Chinese population. Int J Clin Oncol (2012) 0.83
The patch-clamp and planar lipid bilayer techniques: powerful and versatile tools to investigate the CFTR Cl- channel. J Cyst Fibros (2004) 0.82
Stable dimeric assembly of the second membrane-spanning domain of CFTR (cystic fibrosis transmembrane conductance regulator) reconstitutes a chloride-selective pore. Biochem J (2003) 0.82
Crossability barriers in the interspecific hybridization between Oryza sativa and O. meyeriana. J Integr Plant Biol (2009) 0.81
Synthesis and properties of molecular probes for the rescue site on mutant cystic fibrosis transmembrane conductance regulator. J Med Chem (2011) 0.81
Analysis on genetic diversification and heterosis in autotetraploid rice. Springerplus (2013) 0.80
A novel method for monitoring the cytosolic delivery of peptide cargo. J Control Release (2009) 0.80
Temperature dependent Raman spectra of isolated suspended single-walled carbon nanotubes. Nanoscale (2014) 0.80
Targeting the regulation of CFTR channels. Biochem J (2011) 0.80
ATPase assay of purified, reconstituted CFTR protein. J Cyst Fibros (2004) 0.80
Complete genome sequence of virulent bacteriophage SHOU24, which infects foodborne pathogenic Vibrio parahaemolyticus. Arch Virol (2014) 0.80
The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor. Pflugers Arch (2014) 0.79
Downregulation of alpha-fetoprotein siRNA inhibits proliferation of SMMC-7721 cells. World J Gastroenterol (2005) 0.79
Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo--a randomized bilateral comparison study. Photodermatol Photoimmunol Photomed (2013) 0.79
Role of intramolecular and intermolecular interactions in ClC channel and transporter function. Pflugers Arch (2005) 0.78
Abnormalities occurring during female gametophyte development result in the diversity of abnormal embryo sacs and leads to abnormal fertilization in indica/japonica hybrids in rice. J Integr Plant Biol (2009) 0.77
Identification and validation of hits from high throughput screens for CFTR modulators. Curr Pharm Des (2012) 0.77
[In vivo effect of dihydroartemisinin and azithromycin on the ultrastructure of Toxoplasma gondii tachyzoites]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2009) 0.77
Metalloprotease genes of Trichophyton mentagrophytes are important for pathogenicity. Med Mycol (2014) 0.77
Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5. Biochem J (2013) 0.77
Biaxially stretchable supercapacitors based on the buckled hybrid fiber electrode array. Nanoscale (2015) 0.77
In reply. Anesthesiology (2015) 0.75
Bacteria and the neural code. N Engl J Med (2014) 0.75
Epithelial cell chloride channel activity correlates with improved airway function in cystic fibrosis patients with the major mutant: Delta F508. Pediatr Res (2002) 0.75
Designing hybrid gate dielectric for fully printing high-performance carbon nanotube thin film transistors. Nanotechnology (2017) 0.75
Inflammatory Basis of Pulmonary Arterial Hypertension: Implications for Perioperative and Critical Care Medicine. Anesthesiology (2019) 0.75
[Recombinant expression, purification and adhesion function identify of Bacillus anthracis BslA(260 -652) protein]. Wei Sheng Wu Xue Bao (2012) 0.75
Substrate-induced effects on the optical properties of individual ZnO nanorods with different diameters. Nanoscale (2013) 0.75
[Expression of snake venom thrombin-like enzyme calobin in Pichia pastoris]. Sheng Wu Gong Cheng Xue Bao (2009) 0.75
[Inhibitory effect and mechanism of procyanidin from vaccinium on isoprenaline-induced myocardial fibrosis in rats]. Zhongguo Zhong Yao Za Zhi (2012) 0.75
[Development of a killed but metabolically active anthracis vaccine candidate strain]. Sheng Wu Gong Cheng Xue Bao (2011) 0.75
[Myiasis of maxillary sinus and nasal cavity by the larvae of Oestrus ovis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2007) 0.75
Carboxyfluorescein diacetate succinimidyl ester labeling method to study the interaction between Leptospira and macrophages. J Microbiol Methods (2014) 0.75