Published in J Invest Dermatol on April 02, 2009
PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents. J Invest Dermatol (2010) 1.64
The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling. FASEB J (2010) 1.01
Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism. J Biol Chem (2011) 0.96
Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytes. J Biol Chem (2010) 0.95
Desmosomes in vivo. Dermatol Res Pract (2010) 0.89
Protein kinase Calpha puts the hand cuffs on epidermal keratinocyte proliferation. J Invest Dermatol (2009) 0.84
Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation. PLoS One (2013) 0.80
Lipin-1 expression is critical for keratinocyte differentiation. J Lipid Res (2015) 0.78
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun (2016) 0.76
Global Gene Expression Analysis in PKCα(-/-) Mouse Skin Reveals Structural Changes in the Dermis and Defective Wound Granulation Tissue. J Invest Dermatol (2015) 0.75
Protein Kinase Cα (PKCα) Is Resistant to Long Term Desensitization/Down-regulation by Prolonged Diacylglycerol Stimulation. J Biol Chem (2016) 0.75
Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Dermatol Ther (Heidelb) (2016) 0.75
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation. Cell Death Differ (2017) 0.75
Lipid signaling in keratinocytes: Lipin-1 plays a PArt. J Lipid Res (2016) 0.75
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin. Cancer Res (2006) 1.64
Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly. J Cell Biol (2008) 1.47
Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA. Cancer Res (2006) 1.41
Inhibition of PAX3 by TGF-beta modulates melanocyte viability. Mol Cell (2008) 1.26
P21Waf1 control of epithelial cell cycle and cell fate. Crit Rev Oral Biol Med (2002) 1.25
Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration. Mol Carcinog (2010) 1.24
Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene (2002) 1.05
The protein kinase C delta catalytic fragment targets Mcl-1 for degradation to trigger apoptosis. J Biol Chem (2006) 1.04
Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J Biol Chem (2002) 1.01
The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling. FASEB J (2010) 1.01
Bax activation and induction of apoptosis in human keratinocytes by the protein kinase C delta catalytic domain. J Invest Dermatol (2004) 0.98
PKCdelta clustering at the leading edge and mediating growth factor-enhanced, but not ecm-initiated, dermal fibroblast migration. J Invest Dermatol (2006) 0.95
Activation of protein kinase C triggers irreversible cell cycle withdrawal in human keratinocytes. J Invest Dermatol (2002) 0.93
Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene (2005) 0.93
Life and death signaling pathways contributing to skin cancer. J Investig Dermatol Symp Proc (2002) 0.90
Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation. J Invest Dermatol (2009) 0.87
Protein kinase C-delta is commonly expressed in multiple myeloma cells and its downregulation by rottlerin causes apoptosis. Br J Haematol (2003) 0.87
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway. Exp Cell Res (2008) 0.86
Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosis. J Cell Physiol (2004) 0.85
Loss of protein kinase C delta gene expression in human squamous cell carcinomas: a laser capture microdissection study. Am J Pathol (2010) 0.82
The protein kinase Cdelta catalytic fragment is critical for maintenance of the G2/M DNA damage checkpoint. J Biol Chem (2009) 0.82
Defining the caspase-containing apoptotic machinery contributing to cornification in human epidermal equivalents. Exp Dermatol (2006) 0.79
Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition. Am J Hematol (2005) 0.78
Role for Id-1 in immunobiology of normal keratinocytes and in basal cell carcinoma. Exp Dermatol (2003) 0.76
Functional alterations in protein kinase C beta II expression in melanoma. Pigment Cell Melanoma Res (2009) 0.75
FYNagling divergent adhesive functions for Fyn in keratinocytes. Exp Dermatol (2014) 0.75
Mouse models of the skin: models to define mechanisms of skin carcinogenesis. J Skin Cancer (2013) 0.75
Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site. Mol Pharmacol (2012) 0.75