Published in Am J Physiol Gastrointest Liver Physiol on April 02, 2009
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol (2010) 2.50
Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion. Nutr Metab (Lond) (2010) 1.43
Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis. Atherosclerosis (2012) 1.29
Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity. Mediators Inflamm (2010) 1.18
Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion. J Biomed Res (2014) 1.00
Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis. Am J Physiol Endocrinol Metab (2014) 0.91
Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice. J Lipid Res (2011) 0.86
Dietary fructose inhibits lactation-induced adaptations in rat 1,25-(OH)₂D₃ synthesis and calcium transport. FASEB J (2011) 0.84
ApoB/apoA1 is an effective predictor of coronary heart disease risk in overweight and obesity. J Biomed Res (2011) 0.83
Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet. Am J Physiol Endocrinol Metab (2011) 0.82
Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo. Lipids Health Dis (2011) 0.80
Hepatic inflammation induced by high-fructose diet is associated with altered 11βHSD1 expression in the liver of Wistar rats. Eur J Nutr (2014) 0.80
Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice. Diabetes (2016) 0.79
Metabolomic and Lipidomic Analysis of Serum Samples following Curcuma longa Extract Supplementation in High-Fructose and Saturated Fat Fed Rats. PLoS One (2015) 0.76
Proteomic analysis of Terminalia chebula extract-dependent changes in human lymphoblastic T cell protein expression. J Med Food (2012) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev (2002) 4.41
Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nat Genet (2010) 4.01
Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the CALIPER cohort. Clin Chem (2013) 3.58
Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond) (2005) 3.23
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Nature (2010) 2.90
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell Host Microbe (2010) 2.57
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol Biochem Parasitol (2006) 2.39
MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Mol Cell (2005) 2.29
New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process. J Clin Pharmacol (2008) 2.23
Leveraging prior quantitative knowledge to guide drug development decisions and regulatory science recommendations: impact of FDA pharmacometrics during 2004-2006. J Clin Pharmacol (2008) 2.22
Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clin Biochem (2009) 2.00
Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. Am J Physiol Endocrinol Metab (2010) 1.97
Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proc Natl Acad Sci U S A (2010) 1.96
Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clin Chem (2012) 1.90
Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. Am J Physiol Endocrinol Metab (2009) 1.88
A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype. Exp Neurol (2007) 1.82
Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms. Nutr Rev (2007) 1.79
Lipid and lipoprotein dysregulation in insulin resistant states. Clin Chim Acta (2006) 1.73
Irs1 serine 307 promotes insulin sensitivity in mice. Cell Metab (2010) 1.67
Analytical evaluation of the VITROS 5600 Integrated System in a pediatric setting and determination of pediatric reference intervals. Clin Biochem (2010) 1.61
p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion. Gut (2006) 1.56
CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: direct validation using reference samples from the CALIPER cohort. Clin Biochem (2013) 1.52
Dietary fructose and the metabolic syndrome. Curr Opin Gastroenterol (2008) 1.47
Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk. Neurology (2012) 1.44
Retracted Skeletal muscle-specific CPT1 deficiency elevates lipotoxic intermediates but preserves insulin sensitivity. J Diabetes Res (2013) 1.41
A patient with a leg rash, pedal edema, renal failure, and thrombocytopenia. Clin Chem (2009) 1.39
Stress transfer of a Kevlar 49 fiber pullout test studied by micro-Raman spectroscopy. Appl Spectrosc (2013) 1.36
Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. J Lipid Res (2010) 1.36
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. Mol Cancer Res (2011) 1.34
Are patients after Kawasaki disease at increased risk for accelerated atherosclerosis? J Pediatr (2007) 1.33
Structural and histone binding ability characterizations of human PWWP domains. PLoS One (2011) 1.32
Paediatric metabolic syndrome and associated anthropometric indices: the CASPIAN Study. Acta Paediatr (2006) 1.32
DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development (2006) 1.29
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology (2009) 1.24
Analytical measurement and clinical relevance of vitamin D(3) C3-epimer. Clin Biochem (2012) 1.23
Gut-liver interaction in triglyceride-rich lipoprotein metabolism. Am J Physiol Endocrinol Metab (2011) 1.22
Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol (2012) 1.21
MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly. Arterioscler Thromb Vasc Biol (2006) 1.20
Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death. Mol Cell Biol (2004) 1.18
Gap analysis of pediatric reference intervals for risk biomarkers of cardiovascular disease and the metabolic syndrome. Clin Biochem (2006) 1.18
MicroRNAs: emerging roles in lipid and lipoprotein metabolism. Curr Opin Lipidol (2012) 1.17
Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopy. J Biomed Opt (2011) 1.16
Clinical laboratory reference intervals in pediatrics: the CALIPER initiative. Clin Biochem (2009) 1.15
Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36. Gastroenterology (2009) 1.15
AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett (2011) 1.13
A biochemical and functional characterization of diet-induced brain insulin resistance. J Neurochem (2005) 1.12
Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins (2010) 1.11
Association of anthropometric indices with cardiovascular disease risk factors among children and adolescents: CASPIAN Study. Int J Cardiol (2006) 1.11
Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini. J Biol Chem (2011) 1.11
Scientific perspectives on drug transporters and their role in drug interactions. Mol Pharm (2006) 1.11
Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy. Clin Biochem (2010) 1.10
Application of the kurtosis statistic to the evaluation of the risk of hearing loss in workers exposed to high-level complex noise. Ear Hear (2010) 1.10
X-CHIP: an integrated platform for high-throughput protein crystallization and on-the-chip X-ray diffraction data collection. Acta Crystallogr D Biol Crystallogr (2011) 1.09
MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population. Clin Cancer Res (2007) 1.08
RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells. Cancer Sci (2007) 1.07
Preparation and in vitro/in vivo evaluation of insulin-loaded poly(acryloyl-hydroxyethyl starch)-PLGA composite microspheres. Pharm Res (2003) 1.07
Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arterioscler Thromb Vasc Biol (2002) 1.07
Glucosamine-induced endoplasmic reticulum stress promotes ApoB100 degradation: evidence for Grp78-mediated targeting to proteasomal degradation. Arterioscler Thromb Vasc Biol (2004) 1.07
Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly. Biochem Cell Biol (2010) 1.07
Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia. Clin Biochem (2003) 1.05
p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology (2011) 1.05
Canadian Laboratory Initiative on Pediatric Reference Interval Database (CALIPER): pediatric reference intervals for an integrated clinical chemistry and immunoassay analyzer, Abbott ARCHITECT ci8200. Clin Biochem (2009) 1.04
Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis (2008) 1.04
GLP-1 and GLP-2 as yin and yang of intestinal lipoprotein production: evidence for predominance of GLP-2-stimulated postprandial lipemia in normal and insulin-resistant states. Diabetes (2012) 1.03
Factors associated with the metabolic syndrome in a national sample of youths: CASPIAN Study. Nutr Metab Cardiovasc Dis (2007) 1.03
Closing the gaps in paediatric reference intervals: the CALIPER initiative. Clin Biochem Rev (2008) 1.02
C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases. Hepatology (2010) 1.02
Relationship between C-reactive protein and atherosclerotic risk factors and oxidative stress markers among young persons 10-18 years old. Clin Chem (2007) 1.00
Effect of zinc supplementation on markers of insulin resistance, oxidative stress, and inflammation among prepubescent children with metabolic syndrome. Metab Syndr Relat Disord (2010) 1.00
Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. Br J Nutr (2008) 1.00
An insight into statistical refractive index properties of cell internal structure via low-coherence statistical amplitude microscopy. Opt Express (2010) 0.99
Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B. Hepatology (2011) 0.99
Functional polymorphisms and haplotypes in the promoter of the MMP2 gene are associated with risk of nasopharyngeal carcinoma. Hum Mutat (2007) 0.99
Cord blood lipid profile and associated factors: baseline data of a birth cohort study. Paediatr Perinat Epidemiol (2007) 0.99
Role of the kurtosis statistic in evaluating complex noise exposures for the protection of hearing. Ear Hear (2009) 0.99
The effects of the amplitude distribution of equal energy exposures on noise-induced hearing loss: the kurtosis metric. J Acoust Soc Am (2003) 0.98
Comparative brain stem lesions on MRI of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis. PLoS One (2011) 0.98
Autophagy: Emerging roles in lipid homeostasis and metabolic control. Biochim Biophys Acta (2012) 0.98
Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Front Biosci (2003) 0.98
Long-term stability of biochemical markers in pediatric serum specimens stored at -80 °C: a CALIPER Substudy. Clin Biochem (2012) 0.98
Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis (2013) 0.97
Expression and significance of histone H3K27 demethylases in renal cell carcinoma. BMC Cancer (2012) 0.97
Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster. Endocrinology (2004) 0.97
Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia. J Biol Chem (2005) 0.97