Published in Proteins on December 03, 2010
A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. PLoS Pathog (2012) 1.23
Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii. J Med Chem (2013) 1.19
Calcium and reactive oxygen species rule the waves of signaling. Plant Physiol (2013) 1.14
Calcium-dependent protein kinases: hubs in plant stress signaling and development. Plant Physiol (2013) 1.11
The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival. Cell Microbiol (2013) 1.08
Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa. BMC Evol Biol (2011) 0.98
Calcium-dependent protein kinases from Arabidopsis show substrate specificity differences in an analysis of 103 substrates. Front Plant Sci (2011) 0.95
Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. Eur J Med Chem (2014) 0.95
Calcium/Calmodulin-dependent protein kinase is negatively and positively regulated by calcium, providing a mechanism for decoding calcium responses during symbiosis signaling. Plant Cell (2013) 0.93
Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling. Int J Parasitol (2011) 0.91
The Cryptosporidium parvum kinome. BMC Genomics (2011) 0.86
Analysis of Noncanonical Calcium-Dependent Protein Kinases in Toxoplasma gondii by Targeted Gene Deletion Using CRISPR/Cas9. Infect Immun (2016) 0.85
Scaffold Function of Ca2+-Dependent Protein Kinase: Tobacco Ca2+-DEPENDENT PROTEIN KINASE1 Transfers 14-3-3 to the Substrate REPRESSION OF SHOOT GROWTH after Phosphorylation. Plant Physiol (2014) 0.85
Fast and accurate resonance assignment of small-to-large proteins by combining automated and manual approaches. PLoS Comput Biol (2015) 0.82
Novel insights into the regulation of malarial calcium-dependent protein kinase 1. FASEB J (2012) 0.82
Functions of Calcium-Dependent Protein Kinases in Plant Innate Immunity. Plants (Basel) (2014) 0.79
Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture. Antimicrob Agents Chemother (2015) 0.79
Structure of the STRA6 receptor for retinol uptake. Science (2016) 0.78
CDPKs of Cryptosporidium parvum--stage-specific expression in vitro. Parasitol Res (2014) 0.77
Impact of Ca(2+) on structure of soybean CDPKβ and accessibility of the Tyr-24 autophosphorylation site. Plant Signal Behav (2013) 0.76
Phosphorylation-independent binding of 14-3-3 to NtCDPK1 by a new mode. Plant Signal Behav (2014) 0.76
Autophosphorylation-based Calcium (Ca(2+)) Sensitivity Priming and Ca(2+)/Calmodulin Inhibition of Arabidopsis thaliana Ca(2+)-dependent Protein Kinase 28 (CPK28). J Biol Chem (2017) 0.75
Biophysical characterization of the calmodulin-like domain of Plasmodium falciparum calcium dependent protein kinase 3. PLoS One (2017) 0.75
Autophosphorylation Affects Substrate-Binding Affinity of Tobacco Ca2+-Dependent Protein Kinase1. Plant Physiol (2017) 0.75
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. Proc Natl Acad Sci U S A (2006) 4.45
Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nat Genet (2010) 4.01
Protein production and purification. Nat Methods (2008) 3.97
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Nature (2010) 2.90
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell Host Microbe (2010) 2.57
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol Biochem Parasitol (2006) 2.39
MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Mol Cell (2005) 2.29
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma. Nature (2010) 2.25
New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process. J Clin Pharmacol (2008) 2.23
Leveraging prior quantitative knowledge to guide drug development decisions and regulatory science recommendations: impact of FDA pharmacometrics during 2004-2006. J Clin Pharmacol (2008) 2.22
Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proc Natl Acad Sci U S A (2010) 1.96
Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nat Struct Mol Biol (2010) 1.91
Irs1 serine 307 promotes insulin sensitivity in mice. Cell Metab (2010) 1.67
p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion. Gut (2006) 1.56
Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii. EMBO J (2009) 1.50
Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk. Neurology (2012) 1.44
Retracted Skeletal muscle-specific CPT1 deficiency elevates lipotoxic intermediates but preserves insulin sensitivity. J Diabetes Res (2013) 1.41
Stress transfer of a Kevlar 49 fiber pullout test studied by micro-Raman spectroscopy. Appl Spectrosc (2013) 1.36
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. Mol Cancer Res (2011) 1.34
Structural and histone binding ability characterizations of human PWWP domains. PLoS One (2011) 1.32
Screening for ligands using a generic and high-throughput light-scattering-based assay. J Biomol Screen (2006) 1.31
DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development (2006) 1.29
Species identification of medically important fungi by use of real-time LightCycler PCR. J Med Microbiol (2003) 1.26
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands. J Biomol Screen (2009) 1.25
Crystal structure of a gammadelta T-cell receptor specific for the human MHC class I homolog MICA. Proc Natl Acad Sci U S A (2011) 1.24
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology (2009) 1.24
MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly. Arterioscler Thromb Vasc Biol (2006) 1.20
The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport. J Am Chem Soc (2008) 1.19
Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopy. J Biomed Opt (2011) 1.16
AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett (2011) 1.13
Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini. J Biol Chem (2011) 1.11
Scientific perspectives on drug transporters and their role in drug interactions. Mol Pharm (2006) 1.11
Application of the kurtosis statistic to the evaluation of the risk of hearing loss in workers exposed to high-level complex noise. Ear Hear (2010) 1.10
X-CHIP: an integrated platform for high-throughput protein crystallization and on-the-chip X-ray diffraction data collection. Acta Crystallogr D Biol Crystallogr (2011) 1.09
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc Natl Acad Sci U S A (2012) 1.09
MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population. Clin Cancer Res (2007) 1.08
RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells. Cancer Sci (2007) 1.07
Preparation and in vitro/in vivo evaluation of insulin-loaded poly(acryloyl-hydroxyethyl starch)-PLGA composite microspheres. Pharm Res (2003) 1.07
p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology (2011) 1.05
Microbiological, epidemiological, and clinical characteristics and outcomes of patients with cryptococcosis in Taiwan, 1997-2010. PLoS One (2013) 1.04
Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production. Am J Physiol Gastrointest Liver Physiol (2009) 1.03
Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J Biol Chem (2010) 1.03
Jarisch-Herxheimer reaction after penicillin therapy among patients with syphilis in the era of the hiv infection epidemic: incidence and risk factors. Clin Infect Dis (2010) 1.02
Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis. Chem Biol (2008) 1.00
An insight into statistical refractive index properties of cell internal structure via low-coherence statistical amplitude microscopy. Opt Express (2010) 0.99
Functional polymorphisms and haplotypes in the promoter of the MMP2 gene are associated with risk of nasopharyngeal carcinoma. Hum Mutat (2007) 0.99
Role of the kurtosis statistic in evaluating complex noise exposures for the protection of hearing. Ear Hear (2009) 0.99
The effects of the amplitude distribution of equal energy exposures on noise-induced hearing loss: the kurtosis metric. J Acoust Soc Am (2003) 0.98
Comparative brain stem lesions on MRI of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis. PLoS One (2011) 0.98
Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Front Biosci (2003) 0.98
Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis (2013) 0.97
Expression and significance of histone H3K27 demethylases in renal cell carcinoma. BMC Cancer (2012) 0.97
Potential dissolution and photo-dissolution of ZnO thin films. J Hazard Mater (2010) 0.97
The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum. J Mol Biol (2010) 0.96
Characterization of a new phosphatase from Plasmodium. Mol Biochem Parasitol (2011) 0.96
Seroprevalence of chronic hepatitis B virus infection among taiwanese human immunodeficiency virus type 1-positive persons in the era of nationwide hepatitis B vaccination. Am J Gastroenterol (2009) 0.96
IL-22 secreting CD4+ T cells in the patients with neuromyelitis optica and multiple sclerosis. J Neuroimmunol (2013) 0.95
Hepatitis virus in long-fingered bats, Myanmar. Emerg Infect Dis (2013) 0.95
Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis. Eukaryot Cell (2009) 0.95
Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response. J Neuroimmunol (2008) 0.94
A new twist in TCR diversity revealed by a forbidden alphabeta TCR. J Mol Biol (2007) 0.94
Cerebrospinal fluid levels of CXCL13 are elevated in neuromyelitis optica. J Neuroimmunol (2011) 0.94
Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes (2007) 0.93
Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J Mol Biol (2007) 0.93
Hearing loss from interrupted, intermittent, and time varying non-Gaussian noise exposure: The applicability of the equal energy hypothesis. J Acoust Soc Am (2007) 0.92
Splenectomy protects experimental rats from cerebral damage after stroke due to anti-inflammatory effects. Chin Med J (Engl) (2013) 0.92
Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei. Eukaryot Cell (2011) 0.92
Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. J Biol Chem (2014) 0.92
Comparison of four molecular typing methods to assess genetic relatedness of Candida albicans clinical isolates in Taiwan. J Med Microbiol (2005) 0.91
Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector. J Biol Chem (2010) 0.91
Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism (2004) 0.91
[Study on the CNT sensor for strain measurement and its control method of Raman polarization]. Guang Pu Xue Yu Guang Pu Fen Xi (2013) 0.91
Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo. J Exp Clin Cancer Res (2010) 0.91
FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis. Hepatology (2014) 0.90
Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus. Arterioscler Thromb Vasc Biol (2009) 0.90
Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model. J Biomed Opt (2012) 0.90
Chryseobacterium meningosepticum infection: antibiotic susceptibility and risk factors for mortality. J Microbiol Immunol Infect (2008) 0.90
A case of non-O1 and non-O139 Vibrio cholerae septicemia with endophthalmitis in a cirrhotic patient. Jpn J Infect Dis (2008) 0.89
Molecular cloning, characterization and expression analysis of the tumor necrosis factor (TNF) superfamily gene, TNF receptor superfamily gene and lipopolysaccharide-induced TNF-α factor (LITAF) gene from Litopenaeus vannamei. Dev Comp Immunol (2011) 0.89
Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins (2011) 0.89
The effectiveness of N-acetyl-L-cysteine (L-NAC) in the prevention of severe noise-induced hearing loss. Hear Res (2008) 0.89
Lipin-1γ isoform is a novel lipid droplet-associated protein highly expressed in the brain. FEBS Lett (2011) 0.89
Outbreak of influenza A and B among military recruits: evidence from viral culture and polymerase chain reaction. J Microbiol Immunol Infect (2009) 0.89
Serum bilirubin concentrations and multiple sclerosis. J Clin Neurosci (2011) 0.88
Cerebrospinal fluid α-synuclein levels are elevated in multiple sclerosis and neuromyelitis optica patients during replase. J Neurochem (2012) 0.88
Haemophilus parainfluenzae and Fusobacterium necrophorum liver abscess: a case report. J Microbiol Immunol Infect (2002) 0.88