| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
|
J Clin Psychiatry
|
2007
|
7.23
|
|
2
|
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
|
Science
|
2004
|
4.81
|
|
3
|
The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007.
|
Cell Tissue Bank
|
2008
|
4.13
|
|
4
|
Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders.
|
Acta Neuropathol
|
2010
|
2.73
|
|
5
|
Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction.
|
Acta Neuropathol
|
2009
|
2.67
|
|
6
|
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
|
EMBO J
|
2004
|
2.08
|
|
7
|
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
|
Physiol Genomics
|
2006
|
1.88
|
|
8
|
Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles.
|
Acta Neuropathol
|
2006
|
1.64
|
|
9
|
Brain biochemistry in autopsied patients with essential tremor.
|
Mov Disord
|
2011
|
1.56
|
|
10
|
Parkinson disease with dementia: comparing patients with and without Alzheimer pathology.
|
Alzheimer Dis Assoc Disord
|
2009
|
1.54
|
|
11
|
Reduced striatal tyrosine hydroxylase in incidental Lewy body disease.
|
Acta Neuropathol
|
2007
|
1.53
|
|
12
|
Postmortem interval effect on RNA and gene expression in human brain tissue.
|
Cell Tissue Bank
|
2010
|
1.46
|
|
13
|
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.
|
FASEB J
|
2009
|
1.39
|
|
14
|
RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease.
|
Curr Mol Med
|
2007
|
1.38
|
|
15
|
Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease.
|
Neurol Res
|
2004
|
1.28
|
|
16
|
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment.
|
Mitochondrion
|
2006
|
1.25
|
|
17
|
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease.
|
Neurobiol Aging
|
2005
|
1.24
|
|
18
|
Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus.
|
J Neuropathol Exp Neurol
|
2006
|
1.23
|
|
19
|
Microglia activation and anti-inflammatory regulation in Alzheimer's disease.
|
Mol Neurobiol
|
2010
|
1.22
|
|
20
|
Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease.
|
J Neuroinflammation
|
2006
|
1.20
|
|
21
|
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production.
|
Neurobiol Dis
|
2007
|
1.20
|
|
22
|
Submandibular gland needle biopsy for the diagnosis of Parkinson disease.
|
Neurology
|
2014
|
1.19
|
|
23
|
Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues.
|
Exp Cell Res
|
2006
|
1.13
|
|
24
|
Alzheimer's disease and non-demented high pathology control nonagenarians: comparing and contrasting the biochemistry of cognitively successful aging.
|
PLoS One
|
2011
|
1.12
|
|
25
|
Striatal amyloid plaque density predicts Braak neurofibrillary stage and clinicopathological Alzheimer's disease: implications for amyloid imaging.
|
J Alzheimers Dis
|
2012
|
1.04
|
|
26
|
Age-related differences in white matter integrity and cognitive function are related to APOE status.
|
Neuroimage
|
2010
|
1.04
|
|
27
|
Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide.
|
J Neurosci Res
|
2002
|
1.02
|
|
28
|
Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies.
|
Brain Pathol
|
2012
|
1.01
|
|
29
|
Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopaminergic markers.
|
J Neuropathol Exp Neurol
|
2004
|
1.00
|
|
30
|
Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits.
|
Acta Neuropathol
|
2007
|
0.98
|
|
31
|
Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations.
|
Mol Neurodegener
|
2008
|
0.96
|
|
32
|
Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease.
|
Acta Neuropathol
|
2011
|
0.94
|
|
33
|
Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy.
|
Am J Pathol
|
2008
|
0.93
|
|
34
|
Parkinson's disease, cortical dysfunction, and alpha-synuclein.
|
Mov Disord
|
2011
|
0.92
|
|
35
|
Cerebral blood flow in Alzheimer's disease.
|
Vasc Health Risk Manag
|
2012
|
0.91
|
|
36
|
Increased Alzheimer's disease neuropathology is associated with type 2 diabetes and ApoE ε.4 carrier status.
|
Curr Alzheimer Res
|
2013
|
0.87
|
|
37
|
Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson's disease subjects.
|
Neurol Res
|
2012
|
0.87
|
|
38
|
Parkinson's disease dementia and potential therapeutic strategies.
|
CNS Neurosci Ther
|
2010
|
0.86
|
|
39
|
Converging mediators from immune and trophic pathways to identify Parkinson disease dementia.
|
Neurol Neuroimmunol Neuroinflamm
|
2016
|
0.84
|
|
40
|
Reduced clinical and postmortem measures of cardiac pathology in subjects with advanced Alzheimer's Disease.
|
BMC Geriatr
|
2011
|
0.83
|
|
41
|
Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients.
|
J Neurosci Res
|
2005
|
0.82
|
|
42
|
Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging.
|
J Parkinsons Dis
|
2012
|
0.82
|
|
43
|
Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease.
|
Neurosci Lett
|
2009
|
0.80
|
|
44
|
The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease.
|
BMC Neurol
|
2013
|
0.79
|
|
45
|
BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains.
|
Curr Alzheimer Res
|
2013
|
0.78
|
|
46
|
Insulin Modulates In Vitro Secretion of Cytokines and Cytotoxins by Human Glial Cells.
|
Curr Alzheimer Res
|
2015
|
0.77
|
|
47
|
Thiorphan-induced neprilysin inhibition raises amyloid beta levels in rabbit cortex and cerebrospinal fluid.
|
Neurosci Lett
|
2003
|
0.77
|
|
48
|
Absence of effect of chronic nicotine administration on amyloid beta peptide levels in transgenic mice overexpressing mutated human APP (Sw, Ind).
|
Neurosci Lett
|
2008
|
0.77
|
|
49
|
Broad-based nutritional supplementation in 3xTg mice corrects mitochondrial function and indicates sex-specificity in response to Alzheimer's disease intervention.
|
J Alzheimers Dis
|
2012
|
0.77
|
|
50
|
Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology.
|
Biomark Insights
|
2013
|
0.75
|
|
51
|
Cobalt(II) β-ketoaminato complexes as novel inhibitors of neuroinflammation.
|
Eur J Pharmacol
|
2011
|
0.75
|
|
52
|
Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings.
|
Mov Disord
|
2017
|
0.75
|
|
53
|
The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease.
|
J Alzheimers Dis
|
2016
|
0.75
|