F Anthony Lai

Author PubWeight™ 70.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development. Development 2002 3.13
2 Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model. Circ Res 2006 2.81
3 Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. Circ Res 2003 2.44
4 Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. Circ Res 2005 1.86
5 Alternative splicing of ryanodine receptors modulates cardiomyocyte Ca2+ signaling and susceptibility to apoptosis. Circ Res 2007 1.83
6 Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death. Cardiovasc Res 2004 1.72
7 Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6). J Biol Chem 2003 1.59
8 Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies. J Mol Cell Cardiol 2006 1.55
9 Role of phospholipase C-zeta domains in Ca2+-dependent phosphatidylinositol 4,5-bisphosphate hydrolysis and cytoplasmic Ca2+ oscillations. J Biol Chem 2005 1.26
10 Arrhythmogenic mutation-linked defects in ryanodine receptor autoregulation reveal a novel mechanism of Ca2+ release channel dysfunction. Circ Res 2005 1.26
11 Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation. Cardiovasc Res 2010 1.22
12 Ca2+ syntillas, miniature Ca2+ release events in terminals of hypothalamic neurons, are increased in frequency by depolarization in the absence of Ca2+ influx. J Neurosci 2004 1.22
13 Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains. Mol Biol Cell 2004 1.20
14 Ryanodine stores and calcium regulation in the inner segments of salamander rods and cones. J Physiol 2003 1.15
15 Physical coupling between ryanodine receptor-calcium release channels. J Mol Biol 2005 1.14
16 Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins. Circulation 2009 1.14
17 PLCzeta, a sperm-specific PLC and its potential role in fertilization. Biochem Soc Symp 2007 1.14
18 Redox sensitivity of the ryanodine receptor interaction with FK506-binding protein. J Biol Chem 2007 1.13
19 Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues. J Biol Chem 2007 1.11
20 Ryanodine receptor-mediated arrhythmias and sudden cardiac death. Pharmacol Ther 2009 1.08
21 Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain. J Biol Chem 2004 1.07
22 PLCζ and the initiation of Ca(2+) oscillations in fertilizing mammalian eggs. Cell Calcium 2012 1.04
23 Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals. J Neurosci 2006 1.02
24 Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes. Cell Calcium 2004 1.02
25 Two-dimensional crystallization of the ryanodine receptor Ca2+ release channel on lipid membranes. J Struct Biol 2005 1.01
26 Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ. Biochem J 2011 1.01
27 Use of luciferase chimaera to monitor PLCzeta expression in mouse eggs. Methods Mol Biol 2009 1.00
28 Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility. Bioessays 2011 1.00
29 Oligomerization of the cardiac ryanodine receptor C-terminal tail. Biochem J 2003 1.00
30 Differential Ca2+ sensitivity of RyR2 mutations reveals distinct mechanisms of channel dysfunction in sudden cardiac death. Biochem Biophys Res Commun 2005 0.99
31 A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201. Cardiovasc Res 2010 0.98
32 Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region. J Cell Sci 2011 0.98
33 Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation. J Cell Physiol 2010 0.97
34 Syntillas release Ca2+ at a site different from the microdomain where exocytosis occurs in mouse chromaffin cells. Biophys J 2005 0.96
35 Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility. Fertil Steril 2012 0.95
36 Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart. J Cell Sci 2012 0.95
37 Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons. Proc Natl Acad Sci U S A 2013 0.94
38 PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2). Mol Biol Cell 2011 0.94
39 Ryanodine receptor arrays: not just a pretty pattern? Trends Cell Biol 2008 0.93
40 Ryanodine receptor interaction with the SNARE-associated protein snapin. J Cell Sci 2006 0.93
41 Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6. J Biol Chem 2003 0.91
42 Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors). J Biol Chem 2002 0.91
43 Cell cycle-dependent Ca2+ oscillations in mouse embryos are regulated by nuclear targeting of PLCzeta. J Cell Sci 2004 0.88
44 Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes. J Gen Physiol 2011 0.88
45 Novel regulation of PLCζ activity via its XY-linker. Biochem J 2011 0.88
46 Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential. FEBS Lett 2013 0.87
47 Modification of smooth muscle Ca2+-sparks by tetracaine: evidence for sequential RyR activation. Cell Calcium 2007 0.86
48 Central domain of the human cardiac muscle ryanodine receptor does not mediate interaction with FKBP12.6. Cell Biochem Biophys 2005 0.85
49 Regulation of diacylglycerol production and protein kinase C stimulation during sperm- and PLCzeta-mediated mouse egg activation. Biol Cell 2008 0.85
50 N-terminus oligomerization regulates the function of cardiac ryanodine receptors. J Cell Sci 2013 0.83
51 FKBP12.6 binding of ryanodine receptors carrying mutations associated with arrhythmogenic cardiac disease. Biochem J 2009 0.83
52 The dynamics of PKC-induced phosphorylation triggered by Ca2+ oscillations in mouse eggs. J Cell Physiol 2013 0.83
53 Developing new anti-arrhythmics: clues from the molecular basis of cardiac ryanodine receptor (RyR2) Ca2+-release channel dysfunction. Curr Pharm Des 2007 0.83
54 Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization. Mol Hum Reprod 2013 0.82
55 Hax-1 identified as a two-pore channel (TPC)-binding protein. FEBS Lett 2013 0.82
56 Toward a molecular understanding of the structure-function of ryanodine receptor Ca2+ release channels: perspectives from recombinant expression systems. Cell Biochem Biophys 2005 0.82
57 Is PAWP the "real" sperm factor? Asian J Androl 2015 0.82
58 Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection. Fertil Steril 2012 0.81
59 In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6. Biochem J 2003 0.81
60 Divergent effect of mammalian PLCζ in generating Ca²⁺ oscillations in somatic cells compared with eggs. Biochem J 2011 0.81
61 ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor. Biochim Biophys Acta 2013 0.78
62 Molecular nature of sulfhydryl modification by hydrogen peroxide on type 1 ryanodine receptor. Acta Pharmacol Sin 2006 0.78
63 Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study. J Vis Exp 2016 0.77
64 Ryanodine receptor binding to FKBP12 is modulated by channel activation state. J Cell Sci 2005 0.76
65 Bioinformatic mapping and production of recombinant N-terminal domains of human cardiac ryanodine receptor 2. Protein Expr Purif 2010 0.76
66 Ryanodine receptor dysfunction in arrhythmia and sudden cardiac death. Future Cardiol 2005 0.75
67 Ryanodine receptor oligomeric interaction: identification of a putative binding region. J Biol Chem 2004 0.75
68 CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits. J Pharmacol Toxicol Methods 2010 0.75