Published in J Transl Med on April 14, 2009
Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer. J Exp Clin Cancer Res (2010) 1.06
BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification. Mol Cancer (2013) 0.96
The metastasis suppressor, N-myc downregulated gene 1 (NDRG1), is a prognostic biomarker for human colorectal cancer. PLoS One (2013) 0.95
Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry. J Transl Med (2013) 0.92
CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis. Tumour Biol (2014) 0.92
Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU. Oncotarget (2015) 0.88
MTA1 expression correlates significantly with cigarette smoke in non-small cell lung cancer. Virchows Arch (2011) 0.82
Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration. J Neuropathol Exp Neurol (2013) 0.81
Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations. Oncotarget (2015) 0.81
Screening for differentially expressed genes between left- and right-sided colon carcinoma by microarray analysis. Oncol Lett (2013) 0.81
p53 nuclear accumulation and ERalpha expression in ductal hyperplasia of breast in a cohort of 215 Chinese women. J Exp Clin Cancer Res (2010) 0.80
Collagen Triple Helix Repeat Containing-1 (CTHRC1) Expression in Oral Squamous Cell Carcinoma (OSCC): Prognostic Value and Clinico-Pathological Implications. Int J Med Sci (2015) 0.80
The absence of human papillomavirus in esophageal squamous cell carcinoma in East China. Int J Clin Exp Pathol (2014) 0.80
Faecal microbiota transplantation protects against radiation-induced toxicity. EMBO Mol Med (2017) 0.79
RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel. Oncotarget (2015) 0.79
Previous tonsillectomy modifies odds of tonsil and base of tongue cancer. Br J Cancer (2016) 0.79
RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker. Genes Cancer (2015) 0.78
Epigenetic silencing BCL6B induced colorectal cancer proliferation and metastasis by inhibiting P53 signaling. Am J Cancer Res (2015) 0.78
Investigating the expression, effect and tumorigenic pathway of PADI2 in tumors. Onco Targets Ther (2017) 0.75
Infection of Common Marmosets with GB Virus B Chimeric Virus Encoding the Major Nonstructural Proteins NS2 to NS4A of Hepatitis C Virus. J Virol (2016) 0.75
Downregulation of FOXO1 mRNA levels predicts treatment failure in patients with endometrial pathology conservatively managed with progestin-containing intrauterine devices. Gynecol Oncol (2015) 0.75
Expression pattern and methylation of estrogen receptor α in breast intraductal proliferative lesions. Oncol Rep (2016) 0.75
Increasing circulating exosomes-carrying TRPC5 predicts chemoresistance in metastatic breast cancer patients. Cancer Sci (2016) 0.75
Detection of Trichomonas vaginalis in prostate tissue and serostatus in patients with asymptomatic benign prostatic hyperplasia. BMC Infect Dis (2016) 0.75
SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget (2016) 0.75
The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells. Oncogene (2017) 0.75
Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem (1993) 27.24
Basic principles of ROC analysis. Semin Nucl Med (1978) 27.12
Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med (2002) 8.04
Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol (2005) 6.56
A panel of immunohistochemical stains, including carcinoembryonic antigen, vimentin, and estrogen receptor, aids the distinction between primary endometrial and endocervical adenocarcinomas. Int J Gynecol Pathol (2002) 1.90
Differentiation and risk assessment of gastrointestinal stromal tumors. Am J Clin Pathol (1995) 1.72
Mutations associated with familial melanoma impair p16INK4 function. Nat Genet (1995) 1.69
Immunohistochemistry and quantitative analysis of protein expression. Arch Pathol Lab Med (2006) 1.65
Distinction between endometrial and endocervical adenocarcinoma: an immunohistochemical study. Int J Gynecol Pathol (2002) 1.63
Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (QIC score) vs. subjective grading (IRS). Pathol Res Pract (1993) 1.53
Overexpression of the p16 cell cycle inhibitor in breast cancer is associated with a more malignant phenotype. Breast Cancer Res Treat (2001) 1.46
Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. Cancer Res (2007) 1.23
Application of immunohistochemistry to gynecologic pathology. Arch Pathol Lab Med (2008) 1.14
p16 immunoreactivity may assist in the distinction between endometrial and endocervical adenocarcinoma. Int J Gynecol Pathol (2003) 1.13
Immunohistochemistry quantification by a digital computer-assisted method compared to semiquantitative analysis. Clinics (Sao Paulo) (2006) 1.13
Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch (2003) 1.09
Variance in multiplex suspension array assays: carryover of microspheres between sample wells. J Negat Results Biomed (2007) 1.08
Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria. Ann Surg Oncol (2006) 1.06
Differentiation of malignant and benign musculoskeletal tumors: combined color and power Doppler US and spectral wave analysis. Radiology (2002) 1.05
Immunohistochemical staining in the distinction between primary endometrial and endocervical adenocarcinomas: another viewpoint. Int J Gynecol Pathol (2002) 1.04
p16/MTS1 inactivation in ovarian carcinomas: high frequency of reduced protein expression associated with hyper-methylation or mutation in endometrioid and mucinous tumors. Int J Cancer (1998) 1.04
Translational medicine: science or wishful thinking? J Transl Med (2008) 1.04
Immunophenotypic diversity of endometrial adenocarcinomas: implications for differential diagnosis. Mod Pathol (2006) 1.02
Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications. Am J Surg Pathol (2005) 0.97
Adenocarcinoma of the cervix. Curr Treat Options Oncol (2004) 0.94
Nuclear Receptor Interaction Protein (NRIP) expression assay using human tissue microarray and immunohistochemistry technology confirming nuclear localization. J Exp Clin Cancer Res (2008) 0.93
P16/MTS1 and pRB expression in endometrial carcinomas. Virchows Arch (1999) 0.92
p16(INK4A) immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus. J Histochem Cytochem (2003) 0.92
A life in passing: Jonathan Gray. J Transl Med (2007) 0.91
Inclusion of MUC1 (Ma695) in a panel of immunohistochemical markers is useful for distinguishing between endocervical and endometrial mucinous adenocarcinoma. BMC Clin Pathol (2006) 0.87
The fruits of our labors: distinguishing endometrial from endocervical adenocarcinoma. Int J Gynecol Pathol (2002) 0.86
Immunohistochemical detection of p16INK4a in dysplastic lesions of the oral cavity. Mod Pathol (2006) 0.84
[Immunohistochemical expression of p53, p21, p16, and cyclin D1 in superficial bladder cancer. A tissue microarray study]. Actas Urol Esp (2006) 0.82
Ancillary p16(INK4a) adds no meaningful value to the performance of ER/PR/Vim/CEA panel in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray study. Arch Gynecol Obstet (2009) 0.79
MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α. Int J Cancer (2013) 1.59
Maneuvers to decrease laparoscopy-induced shoulder and upper abdominal pain: a randomized controlled study. Arch Surg (2011) 1.56
Unilateral salpingo-oophorectomy as fertility-sparing surgery for borderline ovarian tumors. J Chin Med Assoc (2011) 1.48
Importance of delivered cycles and nomogram for intraperitoneal chemotherapy in ovarian cancer. Gynecol Oncol (2009) 1.46
Prevention of postlaparoscopic shoulder and upper abdominal pain: a randomized controlled trial. Obstet Gynecol (2013) 1.45
Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer Res (2010) 1.44
HER2 gene amplification in primary mucinous ovarian cancer: a potential therapeutic target. Histopathology (2010) 1.43
Association of p53 codon 72 genotypes and clinical outcome in human papillomavirus-infected lung cancer patients. Ann Thorac Surg (2013) 1.41
Hibiscus sabdariffa extract inhibits the development of atherosclerosis in cholesterol-fed rabbits. J Agric Food Chem (2003) 1.33
Single-port compared with conventional laparoscopic-assisted vaginal hysterectomy: a randomized controlled trial. Obstet Gynecol (2011) 1.29
Enhancement of wound healing by human multipotent stromal cell conditioned medium: the paracrine factors and p38 MAPK activation. Cell Transplant (2010) 1.24
Oxidative DNA damage in pterygium. Mol Vis (2005) 1.23
Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status. Ann Surg Oncol (2008) 1.13
A mesoporous silica biomaterial for dental biomimetic crystallization. ACS Nano (2014) 1.12
A polymorphic -844T/C in FasL promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res (2011) 1.09
Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway. Chem Biol Interact (2005) 1.09
Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer. Clin Cancer Res (2011) 1.05
cIAP2 upregulated by E6 oncoprotein via epidermal growth factor receptor/phosphatidylinositol 3-kinase/AKT pathway confers resistance to cisplatin in human papillomavirus 16/18-infected lung cancer. Clin Cancer Res (2010) 1.03
The presence of human papillomavirus type 16/18 DNA in blood circulation may act as a risk marker of lung cancer in Taiwan. Cancer (2003) 1.03
IL-10 promotes tumor aggressiveness via upregulation of CIP2A transcription in lung adenocarcinoma. Clin Cancer Res (2013) 1.02
Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells. Toxicol Appl Pharmacol (2004) 1.02
Child growth from birth to 18 months old born after assisted reproductive technology--results of a national birth cohort study. Int J Nurs Stud (2010) 1.01
Hepatoprotective effect and mechanistic insights of deoxyelephantopin, a phyto-sesquiterpene lactone, against fulminant hepatitis. J Nutr Biochem (2012) 0.98
Hypermethylation of the p16 gene promoter in pterygia and its association with the expression of DNA methyltransferase 3b. Mol Vis (2006) 0.98
Advanced cervical squamous cell carcinoma with skin metastasis. Taiwan J Obstet Gynecol (2007) 0.98
Placenta-derived multipotent stem cells induced to differentiate into insulin-positive cells. Biochem Biophys Res Commun (2007) 0.98
An association of DNMT3b protein expression with P16INK4a promoter hypermethylation in non-smoking female lung cancer with human papillomavirus infection. Cancer Lett (2005) 0.98
Gender difference in estrogen receptor alpha promoter hypermethylation and its prognostic value in non-small cell lung cancer. Int J Cancer (2005) 0.97
Oestrogen-induced epithelial-mesenchymal transition of endometrial epithelial cells contributes to the development of adenomyosis. J Pathol (2010) 0.97
Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol (2012) 0.97
Effect of TIMP-1 and MMP in pterygium invasion. Invest Ophthalmol Vis Sci (2010) 0.97
Scoring of p16(INK4a) immunohistochemistry based on independent nuclear staining alone can sufficiently distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study. Mod Pathol (2009) 0.96
Loss of TIMP-3 promotes tumor invasion via elevated IL-6 production and predicts poor survival and relapse in HPV-infected non-small cell lung cancer. Am J Pathol (2012) 0.96
Assessing the HER2 status in mucinous epithelial ovarian cancer on the basis of the 2013 ASCO/CAP guideline update. Am J Surg Pathol (2014) 0.96
Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS One (2012) 0.95
The protective effects of Hibiscus sabdariffa extract on CCl4-induced liver fibrosis in rats. Food Chem Toxicol (2005) 0.94
Prognostic nomogram for overall survival in stage IIB-IVA cervical cancer patients treated with concurrent chemoradiotherapy. Am J Obstet Gynecol (2009) 0.94
P53 gene mutation spectrum and the relationship between gene mutation and protein levels in pterygium. Mol Vis (2005) 0.94
Nuclear Receptor Interaction Protein (NRIP) expression assay using human tissue microarray and immunohistochemistry technology confirming nuclear localization. J Exp Clin Cancer Res (2008) 0.93
Increased cardiac injury in NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein. Mol Immunol (2011) 0.93
Epidemiology and molecular characterization of macrolide-resistant Streptococcus pyogenes in Taiwan. J Clin Microbiol (2013) 0.92
Autocrine CCL2 promotes cell migration and invasion via PKC activation and tyrosine phosphorylation of paxillin in bladder cancer cells. Cytokine (2012) 0.92
Typical and atypical clinical presentation of uterine myomas. J Chin Med Assoc (2012) 0.91
Frequent p16INK4a promoter hypermethylation in human papillomavirus-infected female lung cancer in Taiwan. Int J Cancer (2005) 0.91
Aggressive characteristics of cervical cancer in young women in Taiwan. Int J Gynaecol Obstet (2009) 0.91
The correlation between aberrant connexin 43 mRNA expression induced by promoter methylation and nodal micrometastasis in non-small cell lung cancer. Clin Cancer Res (2003) 0.91
Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. Neuro Oncol (2012) 0.91
NAT2 fast acetylator genotype is associated with an increased risk of lung cancer among never-smoking women in Taiwan. Cancer Lett (2005) 0.91
Comparing the scoring mechanisms of p16INK4a immunohistochemistry based on independent nucleic stains and independent cytoplasmic stains in distinguishing between endocervical and endometrial adenocarcinomas in a tissue microarray study. Arch Gynecol Obstet (2009) 0.91
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and tolerability of Fufang Danshen (Salvia miltiorrhiza) as add-on antihypertensive therapy in Taiwanese patients with uncontrolled hypertension. Phytother Res (2011) 0.91
Different human papillomavirus 16/18 infection in Chinese non-small cell lung cancer patients living in Wuhan, China. Jpn J Clin Oncol (2006) 0.91
Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer. Anticancer Res (2011) 0.90
p53 Expression in pterygium by immunohistochemical analysis: a series report of 127 cases and review of the literature. Cornea (2005) 0.90
Differential impact of IL-10 expression on survival and relapse between HPV16-positive and -negative oral squamous cell carcinomas. PLoS One (2012) 0.90
Cyclooxygenase 2 expression in pterygium. Mol Vis (2007) 0.89
Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders. Molecules (2010) 0.89
Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro. Mutat Res (2006) 0.89
Polyphenols extracted from Hibiscus sabdariffa L. inhibited lipopolysaccharide-induced inflammation by improving antioxidative conditions and regulating cyclooxygenase-2 expression. Biosci Biotechnol Biochem (2009) 0.89
MnSOD promotes tumor invasion via upregulation of FoxM1-MMP2 axis and related with poor survival and relapse in lung adenocarcinomas. Mol Cancer Res (2012) 0.89
Distinguishing between primary endocervical and endometrial adenocarcinomas: is a 2-marker (Vim/CEA) panel enough? Virchows Arch (2010) 0.89
Balanced and unbalanced reciprocal translocation: an overview of a 30-year experience in a single tertiary medical center in Taiwan. J Chin Med Assoc (2013) 0.89
Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis. Evid Based Complement Alternat Med (2012) 0.88
Pterygium and genetic polymorphisms of the DNA repair enzymes XRCC1, XPA, and XPD. Mol Vis (2010) 0.88
Protective effect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity. Arch Toxicol (2005) 0.87
Null type of glutathione S-transferase M1 polymorphism is associated with early onset pterygium. Mol Vis (2004) 0.87
HPV infection and p53 inactivation in pterygium. Mol Vis (2009) 0.87
Diallyl disulfide inhibits WEHI-3 leukemia cells in vivo. Anticancer Res (2006) 0.87
Inhibition of human alcohol and aldehyde dehydrogenases by acetaminophen: Assessment of the effects on first-pass metabolism of ethanol. Alcohol (2013) 0.87
Up-regulation of interleukin-17 expression by human papillomavirus type 16 E6 in nonsmall cell lung cancer. Cancer (2010) 0.86
Collagen IV significantly enhances migration and transplantation of embryonic stem cells: involvement of α2β1 integrin-mediated actin remodeling. Cell Transplant (2010) 0.86
Extracranial-intracranial (EC-IC) bypass of symptomatic middle cerebral artery (MCA) total occlusion for haemodynamic impairment patients. Br J Neurosurg (2012) 0.86
Identification of the coexisting HER2 gene amplification and novel mutations in the HER2 protein-overexpressed mucinous epithelial ovarian cancer. Ann Surg Oncol (2011) 0.86
The APE1 Asp/Asp genotype and the combination of APE1 Asp/Asp and hOGG1-Cys variants are associated with increased p53 mutation in non-small cell lung cancer. J Epidemiol (2012) 0.86
CyclinD1 protein expressed in pterygia is associated with β-catenin protein localization. Mol Vis (2010) 0.86
An overview of a 30-year experience with amniocentesis in a single tertiary medical center in Taiwan. Taiwan J Obstet Gynecol (2012) 0.85
Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas. PLoS One (2013) 0.85
Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53. DNA Repair (Amst) (2008) 0.85
Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in stage I non-small-cell lung cancer patients with wild-type p53 tumors. Ann Surg Oncol (2009) 0.85
Frequent FHIT gene loss of heterozygosity in human papillomavirus-infected non-smoking female lung cancer in Taiwan. Cancer Lett (2005) 0.85
Prenatal diagnosis of pulmonary sequestration by ultrasound and magnetic resonance imaging. J Chin Med Assoc (2008) 0.85
Innate immunity, decidual cells, and preeclampsia. Reprod Sci (2012) 0.85
In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis. J Clin Periodontol (2012) 0.84