Published in Proc Jpn Acad Ser B Phys Biol Sci on January 01, 2009
Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis. Neuro Oncol (2010) 1.38
Newborns of obese parents have altered DNA methylation patterns at imprinted genes. Int J Obes (Lond) (2013) 1.25
Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer. PLoS One (2013) 1.19
Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation. Asian J Androl (2012) 0.95
Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology. Physiol Genomics (2010) 0.93
Epigenetics of neurological cancers. Future Oncol (2009) 0.85
High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism. Cancer Biol Ther (2014) 0.81
Oncogenic potential of yin yang 1 mediated through control of imprinted genes. Crit Rev Oncog (2011) 0.75
High sensitivity mapping of methylated cytosines. Nucleic Acids Res (1994) 16.62
DNA methylation and human disease. Nat Rev Genet (2005) 12.00
Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol (2002) 3.99
Regulation of maternal behavior and offspring growth by paternally expressed Peg3. Science (1999) 3.07
The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res (2006) 2.50
Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell (2005) 2.17
Methylation-sensitive binding of transcription factor YY1 to an insulator sequence within the paternally expressed imprinted gene, Peg3. Hum Mol Genet (2003) 2.16
Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein. Nat Genet (1996) 2.06
Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. Oncogene (2001) 1.89
Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. Proc Natl Acad Sci U S A (2000) 1.86
Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation. Cancer (2008) 1.69
Peg3/Pw1 is an imprinted gene involved in the TNF-NFkappaB signal transduction pathway. Nat Genet (1998) 1.61
Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer. Cancer Res (2003) 1.54
The human homolog of a mouse-imprinted gene, Peg3, maps to a zinc finger gene-rich region of human chromosome 19q13.4. Genome Res (1997) 1.50
Up-regulation of DLK1 as an imprinted gene could contribute to human hepatocellular carcinoma. Carcinogenesis (2006) 1.33
Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3. FASEB J (2005) 1.31
Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization. Cancer Res (2002) 1.29
Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. Gynecol Oncol (2005) 1.24
Epigenetic silencing of PEG3 gene expression in human glioma cell lines. Mol Carcinog (2001) 1.19
Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia. J Biol Chem (2001) 1.16
In vivo YY1 knockdown effects on genomic imprinting. Hum Mol Genet (2007) 1.13
Peg3/Pw1 is a mediator between p53 and Bax in DNA damage-induced neuronal death. J Biol Chem (2002) 1.07
Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer. Oncogene (2004) 1.06
Allele-specific deposition of macroH2A1 in imprinting control regions. Hum Mol Genet (2006) 1.06
Tumour suppressor activity of human imprinted gene PEG3 in a glioma cell line. Genes Cells (2001) 1.05
Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia. Int J Cancer (2007) 0.99
Cyclophilin a protects Peg3 from hypermethylation and inactive histone modification. J Biol Chem (2006) 0.87
Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines. DNA Res (2004) 0.86
MacroH2A1 knockdown effects on the Peg3 imprinted domain. BMC Genomics (2007) 0.85
Analysis of imprinted murine Peg3 locus in transgenic mice. Mamm Genome (2004) 0.79
Parental 19q loss and PEG3 expression in oligodendrogliomas. Cancer Genet Cytogenet (2004) 0.79
Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat Cell Biol (2004) 5.92
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell (2002) 4.68
Generation of pluripotent stem cells from neonatal mouse testis. Cell (2004) 3.95
Important surgical measures and techniques at cesarean hysterectomy for placenta previa accreta. Acta Obstet Gynecol Scand (2013) 3.91
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet (2004) 3.56
Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis. Development (2005) 3.02
Akt/PKB regulates actin organization and cell motility via Girdin/APE. Dev Cell (2005) 3.01
CTCF-dependent chromatin insulator is linked to epigenetic remodeling. Mol Cell (2006) 2.93
IQGAP1: a key regulator of adhesion and migration. J Cell Sci (2005) 2.65
Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nat Cell Biol (2008) 2.39
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation. J Cell Biol (2007) 2.15
Telomere lengths are characteristic in each human individual. Exp Gerontol (2002) 2.13
Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo. Immunity (2011) 2.12
Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray. Biochem Biophys Res Commun (2002) 1.92
Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling. Genome Res (2003) 1.82
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Res (2008) 1.81
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy. Sci Transl Med (2012) 1.78
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression. Mol Ther (2011) 1.77
Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther (2009) 1.74
Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome. Proc Natl Acad Sci U S A (2004) 1.72
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb. J Hum Genet (2003) 1.72
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nat Cell Biol (2010) 1.72
Transcranial electrical stimulation through screw electrodes for intraoperative monitoring of motor evoked potentials. Technical note. J Neurosurg (2004) 1.68
Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis. J Cell Biol (2007) 1.67
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture. Development (2005) 1.65
Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies. Am J Clin Nutr (2013) 1.61
Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis. Proc Natl Acad Sci U S A (2012) 1.61
Chemical chaperone therapy for brain pathology in G(M1)-gangliosidosis. Proc Natl Acad Sci U S A (2003) 1.57
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res (2010) 1.53
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun (2003) 1.53
Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy. Sci Transl Med (2011) 1.51
Visceral fat thickness in overweight men correlates with alterations in serum fatty acid composition. Clin Chim Acta (2008) 1.50
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome. Am J Med Genet A (2006) 1.48
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle (2007) 1.45
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells. Proc Natl Acad Sci U S A (2006) 1.45
TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases. J Biol Chem (2009) 1.44
Anorectal sleeve micromanometry for the diagnosis of Hirschsprung's disease in newborns. J Pediatr Surg (2007) 1.43
Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis. Clin Gastroenterol Hepatol (2009) 1.43
Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. Proc Natl Acad Sci U S A (2007) 1.41
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta. Drug Metab Dispos (2004) 1.41
Risk factors predictive of lymph node metastasis in depressed early gastric cancer. Am J Surg (2002) 1.40
Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. Mol Biol Cell (2003) 1.39
Mental retardation, spasticity, basal ganglia calcification, cerebral white matter lesions, multiple endocrine defects, telangiectasia and atrophic skin: a new syndrome? Brain Dev (2007) 1.39
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome. Am J Hum Genet (2004) 1.38
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. Cancer Res (2003) 1.35
Ca2+-permeable AMPA receptors regulate growth of human glioblastoma via Akt activation. J Neurosci (2007) 1.35
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation. Cell Stem Cell (2009) 1.35
Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol (2008) 1.34
Diagnostic utility of whole exome sequencing in patients showing cerebellar and/or vermis atrophy in childhood. Neurogenetics (2013) 1.32
Primary bone lymphoma: a new and detailed characterization of 28 patients in a single-institution study. Jpn J Clin Oncol (2007) 1.31
Human artificial chromosomes for gene delivery and the development of animal models. Mol Ther (2011) 1.30
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids. Genomics (2003) 1.29
Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells. Biochem Biophys Res Commun (2010) 1.28
Numb controls E-cadherin endocytosis through p120 catenin with aPKC. Mol Biol Cell (2011) 1.27
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene. Mol Ther (2008) 1.27
Mycobacterium kyorinense sp. nov., a novel, slow-growing species, related to Mycobacterium celatum, isolated from human clinical specimens. Int J Syst Evol Microbiol (2009) 1.27
A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector. PLoS One (2011) 1.26
Endoscopic treatment or surgery for undifferentiated early gastric cancer? Am J Surg (2004) 1.25
IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth. J Cell Sci (2007) 1.24
Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. Blood (2012) 1.23
Global brain atrophy after unilateral parietal lesion and its prevention by erythropoietin. Brain (2005) 1.21
Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun (2008) 1.21
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome. Nucleic Acids Res (2005) 1.21
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells (2010) 1.19
Epigenetic regulation of ARHI in breast and ovarian cancer cells. Ann N Y Acad Sci (2003) 1.18
Hemangiopericytoma in the sacrococcygeal space: a case report. J Med Case Rep (2010) 1.16
Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity. Ann Neurol (2002) 1.16
Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum Mol Genet (2003) 1.15
Predictive factors for lymph node metastasis of differentiated submucosally invasive gastric cancer. Gastrointest Endosc (2004) 1.15
Vaginal lactobacilli and preterm birth. J Perinat Med (2002) 1.15
A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region. J Biol Chem (2002) 1.15
Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy. J Mol Biol (2008) 1.15
Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS One (2011) 1.13
Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin. J Cell Biol (2012) 1.12
Joint angle control by FES using a feedback error learning controller. IEEE Trans Neural Syst Rehabil Eng (2005) 1.12
Dlx5, the mouse homologue of the human-imprinted DLX5 gene, is biallelically expressed in the mouse brain. J Hum Genet (2004) 1.11
Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma. Cancer Sci (2007) 1.11
Cerebral venous sinus thrombosis associated with iron deficiency: two case reports. Neurol Med Chir (Tokyo) (2006) 1.11
NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol (2007) 1.11
Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol (2002) 1.11
Telomere shortening with aging in the human pancreas. Exp Gerontol (2006) 1.10
Primary mediastinal large B-cell lymphoma: a single-institution clinical study in Japan. Int J Hematol (2004) 1.10
Construction of a novel human artificial chromosome vector for gene delivery. Biochem Biophys Res Commun (2004) 1.10
EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells. J Cell Biol (2011) 1.10
Pneumocystis jiroveci pneumonia in relation to CD4+ lymphocyte count in patients with B-cell non-Hodgkin lymphoma treated with chemotherapy. Leuk Lymphoma (2010) 1.09
Phase I / II study of brentuximab vedotin in Japanese patients with relapsed or refractory CD30-positive Hodgkin's lymphoma or systemic anaplastic large-cell lymphoma. Cancer Sci (2014) 1.09
Progressive multifocal leukoencephalopathy in a patient with B-cell lymphoma during rituximab-containing chemotherapy: case report and review of the literature. Int J Hematol (2008) 1.09
Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism. Int J Neuropsychopharmacol (2008) 1.09
Loss of CpG methylation is strongly correlated with loss of histone H3 lysine 9 methylation at DMR-LIT1 in patients with Beckwith-Wiedemann syndrome. Am J Hum Genet (2003) 1.09
Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma. Oncogene (2005) 1.08
Proteomic identification of differentially-expressed genes in human gastric carcinomas. Proteomics (2005) 1.07