Published in J Biol Chem on May 23, 2002
Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor. Proc Natl Acad Sci U S A (2005) 1.65
The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF-binding sites. Hum Mol Genet (2012) 1.16
Beckwith-Wiedemann syndrome caused by maternally inherited mutation of an OCT-binding motif in the IGF2/H19-imprinting control region, ICR1. Eur J Hum Genet (2011) 0.99
Novel cis-regulatory function in ICR-mediated imprinted repression of H19. Dev Biol (2011) 0.95
Oct4/Sox2 binding sites contribute to maintaining hypomethylation of the maternal igf2/h19 imprinting control region. PLoS One (2013) 0.85
Functional characterization of a testis-specific DNA binding activity at the H19/Igf2 imprinting control region. Mol Cell Biol (2003) 0.85
Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells. Mol Cell (2014) 0.84
Induction of DNA demethylation depending on two sets of Sox2 and adjacent Oct3/4 binding sites (Sox-Oct motifs) within the mouse H19/insulin-like growth factor 2 (Igf2) imprinted control region. J Biol Chem (2012) 0.84
Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region. Hum Mol Genet (2014) 0.84
Evidence for anticipation in Beckwith-Wiedemann syndrome. Eur J Hum Genet (2013) 0.82
Oct1 and OCA-B are selectively required for CD4 memory T cell function. J Exp Med (2015) 0.78
The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice. Mol Cell Biol (2012) 0.77
The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks. Biochim Biophys Acta (2016) 0.77
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev (2002) 10.54
Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat Cell Biol (2004) 5.92
Generation of pluripotent stem cells from neonatal mouse testis. Cell (2004) 3.95
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet (2004) 3.56
CTCF-dependent chromatin insulator is linked to epigenetic remodeling. Mol Cell (2006) 2.93
Imaging of ancient schwannoma. AJR Am J Roentgenol (2004) 2.62
Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann Surg Oncol (2008) 2.56
Pancreatic Cancer Registry in Japan: 20 years of experience. Pancreas (2004) 2.30
RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis. Cell Cycle (2011) 2.18
Technical difficulties and their prediction in 2-portal endoscopic carpal tunnel release for idiopathic carpal tunnel syndrome. Arthroscopy (2013) 2.15
Telomere lengths are characteristic in each human individual. Exp Gerontol (2002) 2.13
Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles. J Appl Physiol (1985) (2003) 2.07
Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse. Diabetes (2003) 2.05
Distorted perception of smell by volatile agents facilitated inhalational induction of anesthesia. Paediatr Anaesth (2005) 2.02
Significance of hepatic pedicle lymph node involvement in patients with colorectal liver metastases: a prospective study. Ann Surg Oncol (2002) 2.00
Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray. Biochem Biophys Res Commun (2002) 1.92
Allelic gene regulation of Pcdh-alpha and Pcdh-gamma clusters involving both monoallelic and biallelic expression in single Purkinje cells. J Biol Chem (2006) 1.92
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle (2008) 1.90
The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules. Mol Cell Biol (2002) 1.87
Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome. Hum Mutat (2010) 1.83
Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling. Genome Res (2003) 1.82
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Res (2008) 1.81
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy. Sci Transl Med (2012) 1.78
Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis. J Clin Oncol (2009) 1.78
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression. Mol Ther (2011) 1.77
Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther (2009) 1.74
Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome. Proc Natl Acad Sci U S A (2004) 1.72
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb. J Hum Genet (2003) 1.72
EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma. Int J Cancer (2003) 1.68
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture. Development (2005) 1.65
Oxidative stress in obstructive sleep apnea. Chest (2005) 1.65
Long-term results of computer-assisted posterior occipitocervical reconstruction. World Neurosurg (2010) 1.61
Efficacy and safety of artificial pneumothorax under two-lung ventilation in thoracoscopic esophagectomy for esophageal cancer in the prone position. Gen Thorac Cardiovasc Surg (2013) 1.55
Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes (2008) 1.55
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun (2003) 1.53
Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy. Sci Transl Med (2011) 1.51
Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions. FEBS Lett (2002) 1.50
Mannan-binding lectin (MBL) polymorphism and gastric cancer risk in Japanese population. Dig Dis Sci (2008) 1.49
Clinical Results of Carbon Ion Radiotherapy at NIRS. J Radiat Res (2007) 1.49
Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months. J Tissue Eng Regen Med (2011) 1.48
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome. Am J Med Genet A (2006) 1.48
Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium. Digestion (2007) 1.47
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle (2007) 1.45
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells. Proc Natl Acad Sci U S A (2006) 1.45
Metformin increases the PGC-1alpha protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo. J Appl Physiol (1985) (2006) 1.45
Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J (2007) 1.44
Effects of exercise and amino acid supplementation on body composition and physical function in community-dwelling elderly Japanese sarcopenic women: a randomized controlled trial. J Am Geriatr Soc (2011) 1.44
Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev Cell (2005) 1.43
Women with insufficient 25-hydroxyvitamin D without secondary hyperparathyroidism have altered bone turnover and greater incidence of vertebral fractures. J Orthop Sci (2011) 1.42
Impact of gastropyloric motor activity on the genesis of reflux esophagitis after an esophagectomy with gastric tube reconstruction. Ann Thorac Surg (2013) 1.42
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta. Drug Metab Dispos (2004) 1.41
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome. Am J Hum Genet (2004) 1.38
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys. J Steroid Biochem Mol Biol (2012) 1.38
Significance of the depth of portal vein wall invasion after curative resection for pancreatic adenocarcinoma. Arch Surg (2007) 1.36
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. Cancer Res (2003) 1.35
One or two-stage hepatectomy combined with portal vein embolization for initially nonresectable colorectal liver metastases. Am J Surg (2003) 1.35
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation. Cell Stem Cell (2009) 1.35
The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis. J Clin Immunol (2007) 1.34
MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein. J Biomed Sci (2002) 1.33
Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling. J Cell Sci (2007) 1.32
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas. Mech Dev (2004) 1.31
Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer. Cancer Res (2008) 1.30
Treatment of ulcerative colitis by feeding with germinated barley foodstuff: first report of a multicenter open control trial. J Gastroenterol (2002) 1.30
Involvement of Rab27b in the regulated secretion of pituitary hormones. Endocrinology (2002) 1.30
High-level expression of the Smad ubiquitin ligase Smurf2 correlates with poor prognosis in patients with esophageal squamous cell carcinoma. Cancer Res (2002) 1.30
Endurance exercise increases the SIRT1 and peroxisome proliferator-activated receptor gamma coactivator-1alpha protein expressions in rat skeletal muscle. Metabolism (2008) 1.30
Human artificial chromosomes for gene delivery and the development of animal models. Mol Ther (2011) 1.30
Blunt thyroid trauma with acute hemorrhage and respiratory distress. J Emerg Med (2007) 1.29
Nestin as a marker for proliferative endothelium in gliomas. Lab Invest (2002) 1.29
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo. J Control Release (2008) 1.29
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids. Genomics (2003) 1.29
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene. Mol Ther (2008) 1.27
Vascularized fibular graft after excision of giant-cell tumor of the distal radius: wrist arthroplasty versus partial wrist arthrodesis. Plast Reconstr Surg (2002) 1.27
MiR-150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1. Cancer Sci (2012) 1.27
A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector. PLoS One (2011) 1.26
Toll-like receptor 2 -196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer. Cancer Sci (2007) 1.23
Clinical validation of the gastrointestinal NET grading system: Ki67 index criteria of the WHO 2010 classification is appropriate to predict metastasis or recurrence. Diagn Pathol (2013) 1.22
Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. Mol Cell Biol (2002) 1.22
Long-term clinical and radiographic outcomes after open reduction for missed Monteggia fracture-dislocations in children. J Bone Joint Surg Am (2009) 1.21
Reactive oxygen species-mediated pancreatic beta-cell death is regulated by interactions between stress-activated protein kinases, p38 and c-Jun N-terminal kinase, and mitogen-activated protein kinase phosphatases. Endocrinology (2008) 1.21
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
Pancreaticogastrostomy decreased relaparotomy caused by pancreatic fistula after pancreaticoduodenectomy compared with pancreaticojejunostomy. Arch Surg (2004) 1.21
ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome. Nucleic Acids Res (2005) 1.21
Relationship between clinical markers of glycemia and glucose excursion evaluated by continuous glucose monitoring (CGM). Endocr J (2009) 1.20
Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus. Metabolism (2006) 1.20
Genetic alterations in esophageal cancer. Surg Today (2005) 1.20
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells (2010) 1.19
Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a. J Biol Chem (2004) 1.18
Epigenetic regulation of ARHI in breast and ovarian cancer cells. Ann N Y Acad Sci (2003) 1.18
Constitutive reactive oxygen species generation from autophagosome/lysosome in neuronal oxidative toxicity. J Biol Chem (2009) 1.17
Reduced expression of transforming growth factor-beta receptors is an unfavorable prognostic factor in human esophageal squamous cell carcinoma. Int J Cancer (2003) 1.17
A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals. J Pharmacol Exp Ther (2011) 1.16
Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum Mol Genet (2003) 1.15
Malignant phyllodes tumor of the prostate: retrospective review of specimens obtained by sequential transurethral resection. Pathol Int (2002) 1.14
Obstructive sleep apnea and carotid-artery intima-media thickness. Sleep (2004) 1.14
Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2. Acta Neuropathol (2002) 1.14
Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber. J Virol (2003) 1.13
Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1 (7-36) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia. J Nippon Med Sch (2007) 1.13