Published in Can J Physiol Pharmacol on April 01, 2009
Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND). PLoS One (2014) 0.82
Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA. Am J Physiol Endocrinol Metab (2016) 0.77
Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats. Evid Based Complement Alternat Med (2014) 0.75
Indazole-type alkaloids from Nigella sativa seeds exhibit antihyperglycemic effects via AMPK activation in vitro. J Nat Prod (2014) 0.75
Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction. Am J Physiol Heart Circ Physiol (2006) 1.65
HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone. Exp Biol Med (Maywood) (2009) 1.56
Aging alters tissue resident mesenchymal stem cell properties. Stem Cell Res (2011) 1.47
Peripheral mechanisms of erectile dysfunction in a rat model of chronic cocaine use. Eur Urol (2007) 1.44
Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction. Am J Physiol Heart Circ Physiol (2006) 1.41
HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants. Cardiovasc Toxicol (2004) 1.25
Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases. Expert Opin Biol Ther (2005) 1.24
Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes. Stem Cells (2014) 1.20
Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat. Am J Physiol Heart Circ Physiol (2008) 1.17
Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer. Exp Biol Med (Maywood) (2011) 1.15
Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa. Biopolymers (2010) 1.13
Characterization of the inhibitory effects of erythromycin and clarithromycin on the HERG potassium channel. Mol Cell Biochem (2003) 1.12
The nuclear factor kappa-B signaling pathway as a therapeutic target against thyroid cancers. Thyroid (2012) 1.06
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme. Am J Physiol Heart Circ Physiol (2011) 1.04
Selective blockade of T-type Ca2+ channels suppresses human breast cancer cell proliferation. Cancer Lett (2008) 1.00
Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species. Exp Biol Med (Maywood) (2010) 1.00
MRP (ABCC) transporters-mediated efflux of anti-HIV drugs, saquinavir and zidovudine, from human endothelial cells. Exp Biol Med (Maywood) (2008) 0.99
Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa. J Nat Prod (2010) 0.98
Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18. Am J Physiol Heart Circ Physiol (2012) 0.96
MicroRNA expression profiles in differentiated thyroid cancer, a review. Int J Clin Exp Med (2012) 0.95
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase stimulator, BAY 41-8543, are modulated by nitric oxide. Am J Physiol Heart Circ Physiol (2010) 0.93
Adenovirus-mediated inhibition of NF-kappaB confers chemo-sensitization and apoptosis in prostate cancer cells. Int J Oncol (2003) 0.92
Synergistic inhibition of thyroid cancer by suppressing MAPK/PI3K/AKT pathways. J Surg Res (2013) 0.89
Molecular analysis of cocaine-induced endothelial dysfunction: role of endothelin-1 and nitric oxide. Cardiovasc Toxicol (2008) 0.89
Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat. Am J Physiol Heart Circ Physiol (2010) 0.89
Vascular responses to nitrite are mediated by xanthine oxidoreductase and mitochondrial aldehyde dehydrogenase in the rat. Can J Physiol Pharmacol (2009) 0.88
Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. Cancer Biol Ther (2011) 0.88
Cardiovascular effects of peroxynitrite. Clin Exp Pharmacol Physiol (2007) 0.87
PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-kappaB in metastatic prostate cancer cells. Prostate (2009) 0.86
Rho kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats. Am J Physiol Lung Cell Mol Physiol (2007) 0.86
Effect of chronic sodium nitrite therapy on monocrotaline-induced pulmonary hypertension. Nitric Oxide (2012) 0.85
Superoxide dismutase - a target for gene therapeutic approach to reduce oxidative stress in erectile dysfunction. Methods Mol Biol (2010) 0.85
Suppression of clonogenic potential of human bone marrow mesenchymal stem cells by HIV type 1: putative role of HIV type 1 tat protein and inflammatory cytokines. AIDS Res Hum Retroviruses (2002) 0.85
Zidovudine (AZT) treatment suppresses granulocyte-monocyte colony stimulating factor receptor type alpha (GM-CSFR alpha) gene expression in murine bone marrow cells. Life Sci (2002) 0.84
Rosiglitazone reduces serum homocysteine levels, smooth muscle proliferation, and intimal hyperplasia in Sprague-Dawley rats fed a high methionine diet. Metabolism (2005) 0.84
The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells. Cancers (Basel) (2010) 0.83
Low-dose methylmercury-induced oxidative stress, cytotoxicity, and tau-hyperphosphorylation in human neuroblastoma (SH-SY5Y) cells. Environ Toxicol (2011) 0.83
The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat. Can J Physiol Pharmacol (2012) 0.82
Cytotoxic effects of oxysterols produced during ozonolysis of cholesterol in murine GT1-7 hypothalamic neurons. Free Radic Res (2007) 0.82
The HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP. Exp Biol Med (Maywood) (2005) 0.82
Chronic inhibition of nitric-oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil. BJU Int (2009) 0.82
Mesenchymal stem cell derived hematopoietic cells are permissive to HIV-1 infection. Retrovirology (2011) 0.82
Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat. Am J Physiol Heart Circ Physiol (2010) 0.82
Cycloviolacin O2 (CyO2) suppresses productive infection and augments the antiviral efficacy of nelfinavir in HIV-1 infected monocytic cells. Biopolymers (2013) 0.81
Analysis of responses to glyceryl trinitrate and sodium nitrite in the intact chest rat. Nitric Oxide (2012) 0.81
Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. BJU Int (2008) 0.81
The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells. Exp Biol Med (Maywood) (2005) 0.81
Analysis of erectile responses to BAY 41-8543 and muscarinic receptor stimulation in the rat. J Sex Med (2012) 0.81
Characterization of hematopoietic potential of mesenchymal stem cells. J Cell Physiol (2010) 0.81
Analysis of pulmonary vasodilator responses to SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a novel aminofurazan-based Rho kinase inhibitor. J Pharmacol Exp Ther (2009) 0.81
Specific increase in MDR1 mediated drug-efflux in human brain endothelial cells following co-exposure to HIV-1 and saquinavir. PLoS One (2013) 0.81
Role of VPAC1 and VPAC2 in VIP mediated inhibition of rat pulmonary artery and aortic smooth muscle cell proliferation. Peptides (2010) 0.80
Peroxynitrite has potent pulmonary vasodilator activity in the rat. Can J Physiol Pharmacol (2012) 0.80
Functional androgen receptor confers sensitization of androgen-independent prostate cancer cells to anticancer therapy via caspase activation. Biochem Biophys Res Commun (2003) 0.80
Erythropoietin-induced metallothionein gene expression: role in proliferation of K562 cells. Exp Biol Med (Maywood) (2003) 0.79
Montelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavir. Biol Pharm Bull (2009) 0.78
The selective Rho-kinase inhibitor azaindole-1 has long-lasting erectile activity in the rat. Urology (2013) 0.78
Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture. Food Chem Toxicol (2003) 0.78
Radioprotection in mice following oral administration of WR-1065/PLGA nanoparticles. Int J Radiat Biol (2008) 0.78
Phosphorylated insulin like growth factor-I receptor expression and its clinico-pathological significance in histologic subtypes of human thyroid cancer. Exp Biol Med (Maywood) (2009) 0.78
Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform. Int J Toxicol (2003) 0.78
Effect of binge cocaine treatment on hindlimb vascular function. J Appl Toxicol (2005) 0.78
Role of the RhoA/Rho-kinase pathway in the regulation of pulmonary vasoconstrictor function. Can J Physiol Pharmacol (2010) 0.77
A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis. Biopolymers (2013) 0.77
Attenuation of low dose methylmercury and glutamate induced-cytotoxicity and tau phosphorylation by an N-methyl-D-aspartate antagonist in human neuroblastoma (SHSY5Y) cells. Environ Toxicol (2011) 0.76
Determination of glutathione, mitochondrial transmembrane potential, and cytotoxicity in H9c2 cardiomyoblasts exposed to reactive oxygen and nitrogen species. Methods Mol Biol (2010) 0.76
Methods in assessing homocysteine metabolism. Metab Syndr Relat Disord (2003) 0.76
Intracavernosal administration of sodium nitrite as an erectile pharmacotherapy. Can J Physiol Pharmacol (2010) 0.76
Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J (2013) 0.75
Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the lung for pulmonary hypertension. Methods Mol Biol (2010) 0.75
History of right heart catheterization: 100 years of experimentation and methodology development. Cardiol Rev (2010) 0.75
Upregulation of HTLV-1 and HTLV-2 expression by HIV-1 in vitro. J Med Virol (2008) 0.75
Intracellular oxidative stress and cytotoxicity in rat primary cortical neurons exposed to cholesterol secoaldehyde. Biochem Biophys Res Commun (2009) 0.75
Recyclable single-stranded DNA template for synthesis of siRNAs. BMB Rep (2010) 0.75
Dose-dependent liver tissue repair in chloroform plus thioacetamide acute hepatotoxicity. Environ Toxicol Pharmacol (2004) 0.75
Neuronal stem cells biology and plasticity. Cancer Invest (2003) 0.75
Effect of acute intravenous cocaine administration on endothelium-dependent vasodepressor responses to acetylcholine. J Cardiovasc Pharmacol Ther (2003) 0.75
Novel "breath figure"-based synthetic PLGA matrices for in vitro modeling of mammary morphogenesis and assessing chemotherapeutic response. Adv Healthc Mater (2013) 0.75