Published in Hum Genet on April 17, 2009
GWAS: heritability missing in action? Eur J Hum Genet (2010) 1.20
Characterization of X-linked SNP genotypic variation in globally distributed human populations. Genome Biol (2010) 1.02
Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation. PLoS One (2015) 0.99
Characteristics of androgenetic alopecia in asian. Ann Dermatol (2012) 0.91
Evolutionary forces shaping genomic islands of population differentiation in humans. BMC Genomics (2012) 0.82
Evaluation of DNA variants associated with androgenetic alopecia and their potential to predict male pattern baldness. PLoS One (2015) 0.79
Mutational spectrum in 101 patients with hypohidrotic ectodermal dysplasia and breakpoint mapping in independent cases of rare genomic rearrangements. J Hum Genet (2016) 0.77
Lower prostate cancer risk in Swedish men with the androgen receptor E213 A-allele. Cancer Causes Control (2017) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A haplotype map of the human genome. Nature (2005) 105.70
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The structure of haplotype blocks in the human genome. Science (2002) 50.88
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
A high-resolution recombination map of the human genome. Nat Genet (2002) 28.66
Detecting recent positive selection in the human genome from haplotype structure. Nature (2002) 22.00
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Hitchhiking under positive Darwinian selection. Genetics (2000) 14.72
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature (1991) 9.89
Androgen receptor in prostate cancer. Endocr Rev (2004) 7.92
Natural selection has driven population differentiation in modern humans. Nat Genet (2008) 7.48
Detecting a local signature of genetic hitchhiking along a recombining chromosome. Genetics (2002) 7.43
Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nat Genet (2007) 6.63
Identifying adaptive genetic divergence among populations from genome scans. Mol Ecol (2004) 5.31
Recent and ongoing selection in the human genome. Nat Rev Genet (2007) 4.62
Signatures of natural selection in the human genome. Nat Rev Genet (2003) 3.84
Patterned loss of hair in man; types and incidence. Ann N Y Acad Sci (1951) 3.70
The fate of mutations surfing on the wave of a range expansion. Mol Biol Evol (2005) 3.54
Male pattern baldness: classification and incidence. South Med J (1975) 3.30
Epidemiology of male breast cancer. Cancer Epidemiol Biomarkers Prev (2005) 3.22
The androgen receptor gene mutations database (ARDB): 2004 update. Hum Mutat (2004) 2.25
Accelerated genetic drift on chromosome X during the human dispersal out of Africa. Nat Genet (2008) 2.22
A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Hum Mol Genet (2007) 1.96
Selective sweep mapping of genes with large phenotypic effects. Genome Res (2005) 1.95
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science (2000) 1.95
Male-pattern baldness susceptibility locus at 20p11. Nat Genet (2008) 1.87
Susceptibility variants for male-pattern baldness on chromosome 20p11. Nat Genet (2008) 1.80
Edar signaling in the control of hair follicle development. J Investig Dermatol Symp Proc (2005) 1.54
EDA2R is associated with androgenetic alopecia. J Invest Dermatol (2008) 1.44
Confounding between recombination and selection, and the Ped/Pop method for detecting selection. Genome Res (2008) 1.42
Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form. Hum Mutat (2008) 1.39
Polymorphism of the androgen receptor gene is associated with male pattern baldness. J Invest Dermatol (2001) 1.37
Phenotypic heterogeneity of mutations in androgen receptor gene. Asian J Androl (2007) 1.36
Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection. Ann Hum Genet (2008) 1.35
Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. Am J Hum Genet (2005) 1.35
Recent advances in androgen receptor action. Cell Mol Life Sci (2003) 1.34
Effect of castration in adolescent and young adult males upon further changes in the proportions of bare and hairy scalp. J Clin Endocrinol Metab (1960) 1.25
Identification and analysis of genomic regions with large between-population differentiation in humans. Ann Hum Genet (2008) 1.25
Hair patterns of scalp of white and Negro males. Am J Phys Anthropol (1970) 1.17
Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation. PLoS One (2008) 1.14
Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia. Hum Genet (2007) 1.14
Aberrant splicing of androgen receptor mRNA results in synthesis of a nonfunctional receptor protein in a patient with androgen insensitivity. Proc Natl Acad Sci U S A (1990) 1.10
The E211 G>A androgen receptor polymorphism is associated with a decreased risk of metastatic prostate cancer and androgenetic alopecia. Cancer Epidemiol Biomarkers Prev (2005) 1.04
Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency. Mol Cell Biol (2004) 1.03
Hormonal regulation of hair follicles exhibits a biological paradox. Semin Cell Dev Biol (2007) 1.02
The prevalence and types of androgenetic alopecia in Korean men and women. Br J Dermatol (2001) 1.01
Genome-wide scan and fine-mapping linkage study of androgenetic alopecia reveals a locus on chromosome 3q26. Am J Hum Genet (2008) 0.93
Enrichment of HapMap recombination hotspot predictions around human nervous system genes: evidence for positive selection? Eur J Hum Genet (2007) 0.90
A random study of Asian male androgenetic alopecia in Bangkok, Thailand. Dermatol Surg (2002) 0.85
A community study of male androgenetic alopecia in Bishan, Singapore. Singapore Med J (2000) 0.78
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell (2008) 28.29
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
International network of cancer genome projects. Nature (2010) 20.35
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Landscape of transcription in human cells. Nature (2012) 20.18
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res (2012) 15.41
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
An oestrogen-receptor-alpha-bound human chromatin interactome. Nature (2009) 12.16
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Functional metagenomic profiling of nine biomes. Nature (2008) 11.00
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell (2012) 8.41
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation. Nat Methods (2005) 7.87
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05
CTCF-mediated functional chromatin interactome in pluripotent cells. Nat Genet (2011) 6.55
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat Genet (2009) 6.39
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A (2006) 5.27
Global diversity in the human salivary microbiome. Genome Res (2009) 5.16
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet (2012) 5.11
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
RNA viral community in human feces: prevalence of plant pathogenic viruses. PLoS Biol (2006) 4.93
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. Nat Med (2012) 4.90
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat Genet (2012) 4.82
Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78
Mapping of transcription factor binding regions in mammalian cells by ChIP: comparison of array- and sequencing-based technologies. Genome Res (2007) 4.59
Multiplex sequencing of paired-end ditags (MS-PET): a strategy for the ultra-high-throughput analysis of transcriptomes and genomes. Nucleic Acids Res (2006) 4.51
Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses. Genome Res (2009) 4.47
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Pseudogenes in the ENCODE regions: consensus annotation, analysis of transcription, and evolution. Genome Res (2007) 3.82
Evolution of the mammalian transcription factor binding repertoire via transposable elements. Genome Res (2008) 3.76
Agriculture: Feeding the future. Nature (2013) 3.75
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
A new approach for using genome scans to detect recent positive selection in the human genome. PLoS Biol (2007) 3.71
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet (2009) 3.58
Targeted high-throughput sequencing of tagged nucleic acid samples. Nucleic Acids Res (2007) 3.56
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell (2012) 3.52
ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing. Genome Biol (2010) 3.24
How culture shaped the human genome: bringing genetics and the human sciences together. Nat Rev Genet (2010) 3.21
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet (2010) 3.21
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Genetic associations with valvular calcification and aortic stenosis. N Engl J Med (2013) 3.02
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. Nat Genet (2008) 3.00
Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol Biol Evol (2006) 2.98
Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes. Am J Hum Genet (2010) 2.98
Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. Nat Genet (2009) 2.93
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
The draft genome of sweet orange (Citrus sinensis). Nat Genet (2012) 2.81
Single nucleotide variation analysis in 65 candidate genes for CNS disorders in a representative sample of the European population. Genome Res (2003) 2.75
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Biodiversity and biogeography of phages in modern stromatolites and thrombolites. Nature (2008) 2.70
Understanding transcriptional regulation by integrative analysis of transcription factor binding data. Genome Res (2012) 2.66
Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat Methods (2012) 2.64
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One (2010) 2.57
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet (2010) 2.46
Mitochondrial DNA and human evolution. Annu Rev Genomics Hum Genet (2005) 2.36
Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics (2008) 2.32
Transcriptome analysis of zebrafish embryogenesis using microarrays. PLoS Genet (2005) 2.32
Systematic evaluation of factors influencing ChIP-seq fidelity. Nat Methods (2012) 2.31
A genome scan to detect candidate regions influenced by local natural selection in human populations. Mol Biol Evol (2003) 2.30
Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes. Diabetes Care (2006) 2.24
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes. J Hum Genet (2005) 2.19
Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell (2013) 2.17
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet (2012) 2.15
A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals. Science (2007) 2.15
Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature (2010) 2.10
Molecular evolution of Pediculus humanus and the origin of clothing. Curr Biol (2003) 2.09
Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry (2010) 2.07
Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation. Mol Cell (2007) 2.05
Integrative model of genomic factors for determining binding site selection by estrogen receptor-α. Mol Syst Biol (2010) 2.04
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Genome-wide analysis indicates more Asian than Melanesian ancestry of Polynesians. Am J Hum Genet (2008) 2.02