Published in Hemoglobin on January 01, 2009
Hypercoagulability and thrombotic complications in hemolytic anemias. Haematologica (2009) 1.36
Severe FVII deficiency caused by a new point mutation combined with a previously undetected gene deletion. Br J Haematol (2005) 2.00
Identifying unprovoked thromboembolism patients at low risk for recurrence who can discontinue anticoagulant therapy. CMAJ (2008) 1.71
Recognition and management of methemoglobinemia and hemolysis in a G6PD-deficient patient on experimental anticancer drug Triapine. Am J Hematol (2006) 1.69
Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells. Proc Natl Acad Sci U S A (2002) 1.61
Expression, purification, and characterization of authentic monoferric and apo-human serum transferrins. Protein Expr Purif (2004) 1.25
Investigation of the mechanism of iron release from the C-lobe of human serum transferrin: mutational analysis of the role of a pH sensitive triad. Biochemistry (2003) 1.23
Effect of glycosylation on the function of a soluble, recombinant form of the transferrin receptor. Biochemistry (2006) 1.23
A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia. Blood (2012) 1.22
Intrinsic fluorescence reports a global conformational change in the N-lobe of human serum transferrin following iron release. Biochemistry (2007) 1.13
Differential effect of a his tag at the N- and C-termini: functional studies with recombinant human serum transferrin. Biochemistry (2002) 1.12
Mutational analysis of C-lobe ligands of human serum transferrin: insights into the mechanism of iron release. Biochemistry (2005) 1.09
Synergistic anion and metal binding to the ferric ion-binding protein from Neisseria gonorrhoeae. J Biol Chem (2002) 1.08
A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7. Br J Haematol (2007) 1.05
Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin. J Biol Inorg Chem (2010) 1.03
Iron overload in myelodysplastic syndromes: a Canadian consensus guideline. Leuk Res (2008) 1.03
An assessment of published pediatric dosage guidelines for enoxaparin: a retrospective review. J Pediatr Hematol Oncol (2004) 1.00
Composition of pH-sensitive triad in C-lobe of human serum transferrin. Comparison to sequences of ovotransferrin and lactoferrin provides insight into functional differences in iron release. Biochemistry (2005) 0.96
A loop in the N-lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis, isothermal titration calorimetry, and epitope mapping. J Mol Recognit (2009) 0.95
Genetically engineering transferrin to improve its in vitro ability to deliver cytotoxins. J Control Release (2008) 0.95
Inequivalent contribution of the five tryptophan residues in the C-lobe of human serum transferrin to the fluorescence increase when iron is released. Biochemistry (2009) 0.94
Recombinant expression and functional characterization of human hephaestin: a multicopper oxidase with ferroxidase activity. Biochemistry (2005) 0.93
Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells. Am J Physiol Gastrointest Liver Physiol (2009) 0.92
Multi-copper oxidases and human iron metabolism. Nutrients (2013) 0.90
Blood iron homeostasis: newly discovered proteins and iron imbalance. Transfus Med Rev (2009) 0.88
The position of arginine 124 controls the rate of iron release from the N-lobe of human serum transferrin. A structural study. J Biol Chem (2002) 0.87
Maximizing filamentous phage yield during computer-controlled fermentation. Bioprocess Biosyst Eng (2009) 0.86
Structure-based mutagenesis reveals critical residues in the transferrin receptor participating in the mechanism of pH-induced release of iron from human serum transferrin. Biochemistry (2012) 0.83
Cytochrome b(5) is a major reductant in vivo of human indoleamine 2,3-dioxygenase expressed in yeast. FEBS Lett (2006) 0.83
Risk of recurrent venous thromboembolism after a first oestrogen-associated episode. Data from the REVERSE cohort study. Thromb Haemost (2010) 0.83
High density array screening to identify the genetic requirements for transition metal tolerance in Saccharomyces cerevisiae. Metallomics (2011) 0.82
Combined neutrophil and erythrocyte agglutination in a 7-year-old boy. J Pediatr Hematol Oncol (2007) 0.82
Engineering the primary substrate specificity of Streptomyces griseus trypsin. Biochemistry (2003) 0.82
Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation. CMAJ (2003) 0.82
Conversion of trypsin into a Na(+)-activated enzyme. Biochemistry (2006) 0.82
Identification of the epitope of a monoclonal antibody that disrupts binding of human transferrin to the human transferrin receptor. FEBS J (2005) 0.82
Ionic residues of human serum transferrin affect binding to the transferrin receptor and iron release. Biochemistry (2012) 0.81
Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin. Protein Expr Purif (2010) 0.81
Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin. Biochemistry (2009) 0.81
Utility of anti-xa monitoring in children receiving enoxaparin for therapeutic anticoagulation. J Pediatr Pharmacol Ther (2005) 0.81
A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. Biochem J (2007) 0.80
Combination hemodialysis and centrifugal therapeutic plasma exchange: 18 years of Canadian experience. Hemodial Int (2012) 0.80
In Utero diagnosis and management of a fetus with homozygous α-Thalassemia in the second trimester: a case report and literature review. J Pediatr Hematol Oncol (2011) 0.79
Low prevalence of JAK2 V617F mutation in patients with first unprovoked venous thromboembolism. Br J Haematol (2011) 0.78
Exflagellating Plasmodium vivax in peripheral blood. Arch Pathol Lab Med (2003) 0.78
Oxidation of organic and biogenic amines by recombinant human hephaestin expressed in Pichia pastoris. Arch Biochem Biophys (2011) 0.78
Proteomics: applications relevant to transfusion medicine. Transfus Med Rev (2006) 0.77
Functional analysis of three recombinant A1-VWF domain mutants in comparison to wild type and plasma-derived VWF facilitates subtyping in type 2 von Willebrand disease. Thromb Res (2010) 0.77
Characterization of a nucleotide-binding domain associated with neisserial iron transport. J Bacteriol (2004) 0.77
A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V. Br J Haematol (2010) 0.77
Optimization of fermentation parameters in phage production using response surface methodology. J Ind Microbiol Biotechnol (2012) 0.76
Molecular determination of the breakpoints of a 161 556 bp deletion at chromosome 13q34 that presented as severe factor VII deficiency in a neonate. Br J Haematol (2007) 0.75
Bacteriophage-induced aggregation of oil sands tailings. Biotechnol Bioeng (2012) 0.75
Effects of bacteriophage on the surface properties of chalcopyrite (CuFeS₂), and phage-induced flocculation of chalcopyrite, glacial till, and oil sands tailings. Biotechnol Bioeng (2011) 0.75
Germline mutation identified after amplification of nuclear DNA from citrated plasma. Br J Haematol (2006) 0.75
Differential contributions of Glu96, Asp102 and Asp111 to coagulation factor V/Va metal ion binding and subunit stability. Biochem J (2009) 0.75
Microdeletion of exon 3 in the HBA2 gene associated with mild α-thalassemia trait. Hemoglobin (2013) 0.75
Retinal hemorrhages requiring vitrectomy in a patient with hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer (2008) 0.75
Hyperuricemia and reticulocytopenia in association with autoimmune hemolytic anemia in two children. Am J Clin Pathol (2004) 0.75
Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major. Br J Haematol (2013) 0.75