Published in Bioessays on June 01, 2009
Dynamic aberrant NF-κB spurs tumorigenesis: a new model encompassing the microenvironment. Cytokine Growth Factor Rev (2015) 0.83
Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα. PLoS One (2012) 0.75
Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials. J Gerontol A Biol Sci Med Sci (2005) 3.14
Midline carcinoma of children and young adults with NUT rearrangement. J Clin Oncol (2004) 2.92
A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab (2006) 2.80
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr (2003) 2.65
Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab (2003) 2.41
Testosterone administration to older men improves muscle function: molecular and physiological mechanisms. Am J Physiol Endocrinol Metab (2002) 2.24
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J Appl Physiol (1985) (2008) 2.20
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr (2005) 2.15
Management of blood glucose in type 2 diabetes mellitus. Am Fam Physician (2009) 2.09
Trends in androgen prescribing in the United States, 2001 to 2011. JAMA Intern Med (2013) 2.05
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res (2007) 1.79
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc (2009) 1.70
Endocrine control of body composition in infancy, childhood, and puberty. Endocr Rev (2005) 1.67
Intramuscular and liver triglycerides are increased in the elderly. J Clin Endocrinol Metab (2004) 1.62
Novel noninvasive breath test method for screening individuals at risk for diabetes. Diabetes Care (2008) 1.57
Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. J Clin Endocrinol Metab (2006) 1.56
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol (2005) 1.53
Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women. J Clin Endocrinol Metab (2009) 1.45
Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab (2004) 1.43
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer. Nat Cell Biol (2013) 1.36
SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1. Mol Cell (2009) 1.30
Organic cation transporter 3: Keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice. Proc Natl Acad Sci U S A (2008) 1.29
Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling. J Clin Endocrinol Metab (2010) 1.24
Environmental factors and genetic susceptibility promote urinary bladder cancer. Toxicol Lett (2010) 1.20
Inflammatory burden and amino acid metabolism in cancer cachexia. Curr Opin Clin Nutr Metab Care (2009) 1.17
Differential anabolic effects of testosterone and amino acid feeding in older men. J Clin Endocrinol Metab (2003) 1.16
Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults. Diabetes (2010) 1.13
Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men. J Clin Endocrinol Metab (2002) 1.13
The role of androgens and estrogens on healthy aging and longevity. J Gerontol A Biol Sci Med Sci (2012) 1.13
Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am J Physiol Endocrinol Metab (2004) 1.09
Age-related anabolic resistance after endurance-type exercise in healthy humans. FASEB J (2010) 1.09
Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein. Clin Nutr (2012) 1.09
The role of ATF-2 in oncogenesis. Bioessays (2008) 1.08
Effect of growth hormone replacement therapy on cognition after traumatic brain injury. J Neurotrauma (2010) 1.08
Early indicators of dysmetabolic syndrome in young survivors of acute lymphoblastic leukemia in childhood as a target for preventing disease. J Pediatr Hematol Oncol (2007) 1.06
p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner. EMBO J (2003) 1.06
An overview of the endocrinology of skeletal muscle. Trends Endocrinol Metab (2004) 1.02
The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation. J Clin Endocrinol Metab (2004) 1.01
A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial-to-mesenchymal transition. Cancer Res (2009) 0.99
Successful long-term immunologic reconstitution by allogeneic hematopoietic stem cell transplantation cures patients with autosomal dominant hyper-IgE syndrome. J Allergy Clin Immunol (2010) 0.98
Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy. Clin Nutr (2007) 0.98
Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas. Am J Pathol (2009) 0.97
The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci (2012) 0.96
Method for the determination of the arteriovenous muscle protein balance during non-steady-state blood and muscle amino acid concentrations. Am J Physiol Endocrinol Metab (2005) 0.95
Androgen therapy induces muscle protein anabolism in older women. J Clin Endocrinol Metab (2006) 0.94
Overexpression of activating transcription factor-2 is required for tumor growth and progression in mouse skin tumors. Cancer Res (2004) 0.92
High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling. J Biol Chem (2002) 0.92
Plasma triglycerides are not related to tissue lipids and insulin sensitivity in elderly following PPAR-alpha agonist treatment. Mech Ageing Dev (2007) 0.92
Skeletal muscle protein anabolic response to increased energy and insulin is preserved in poorly controlled type 2 diabetes. J Nutr (2006) 0.91
Estrogen receptor alpha and beta in uterine fibroids: a basis for altered estrogen responsiveness. Fertil Steril (2007) 0.90
Favorable outcome of Ewing sarcoma family tumors to multiagent intensive preoperative chemotherapy: a single institution experience. J Surg Oncol (2005) 0.90
Evaluation of cadmium-induced transcriptome alterations by three color cDNA labeling microarray analysis on a T-cell line. Toxicology (2002) 0.89
The frequency of NPM1 mutations in childhood acute myeloid leukemia. J Hematol Oncol (2010) 0.89
Pathogenesis of muscle wasting in cancer cachexia: targeted anabolic and anticatabolic therapies. Curr Opin Clin Nutr Metab Care (2010) 0.89
Identification of ERK and JNK as signaling mediators on protein kinase C activation in cultured granulosa cells. Mol Cell Endocrinol (2008) 0.88
Pathway simulations in common oncogenic drivers of leukemic and rhabdomyosarcoma cells: a systems biology approach. Int J Oncol (2012) 0.88
A randomized pilot study of monthly cycled testosterone replacement or continuous testosterone replacement versus placebo in older men. J Clin Endocrinol Metab (2011) 0.87
Skeletal muscle is anabolically unresponsive to an amino acid infusion in pediatric burn patients 6 months postinjury. Ann Surg (2011) 0.87
Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids. Am J Physiol Endocrinol Metab (2003) 0.87
Primary gastric Burkitt lymphoma in childhood: associated with Helicobacter pylori? Med Pediatr Oncol (2003) 0.87
Subacute vertebral osteomyelitis in a child with diabetes mellitus associated with Fusarium. Pediatr Int (2004) 0.86
Global DNA hypomethylation-induced ΔNp73 transcriptional activation in non-small cell lung cancer. Cancer Lett (2011) 0.86
Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. J Invest Dermatol (2012) 0.86
Identification of serum biomarkers for aging and anabolic response. Immun Ageing (2011) 0.86
Protein biomarkers distinguish between high- and low-risk pediatric acute lymphoblastic leukemia in a tissue specific manner. J Hematol Oncol (2013) 0.85
Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia. Am J Physiol Regul Integr Comp Physiol (2011) 0.85
Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation. Proteins (2009) 0.84
Serum lipid alterations in acute lymphoblastic leukemia of childhood. J Pediatr Hematol Oncol (2004) 0.83
Hormone treatment and muscle anabolism during aging: androgens. Clin Nutr (2010) 0.83
Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression. Leuk Res (2009) 0.82
Desmoplastic small round cell tumor of the pleura. Pediatr Blood Cancer (2007) 0.82
The use of DNA microarrays to assess clinical samples: the transition from bedside to bench to bedside. Recent Prog Horm Res (2003) 0.82
JNK and ERK signaling pathways in multistage mouse carcinogenesis: studies in the inhibition of signaling cascades as a means to understand their in vivo biological role. Anticancer Res (2002) 0.82
Effects of raloxifene on insulin sensitivity, beta-cell function, and hepatic insulin extraction in normal postmenopausal women. Fertil Steril (2007) 0.82
Serial plasma concentrations of PYY and ghrelin during chemotherapy in children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol (2008) 0.82
How do cytokines trigger genomic instability? J Biomed Biotechnol (2012) 0.82
IGF-1 controls GLUT3 expression in muscle via the transcriptional factor Sp1. Biochim Biophys Acta (2007) 0.82
Enteroviral infections in children with malignant disease: a 5-year study in a single institution. J Infect (2006) 0.81
Clinical remission following monoclonal anti-CD20 therapy in two children with chronic refractory idiopathic thrombocytopenic purpura. J Paediatr Child Health (2005) 0.81
Interleukin-10 regulated gene expression in cells of hypothalamic-pituitary-adrenal axis origin. Cell Mol Neurobiol (2007) 0.81
Effect of recombinant growth hormone replacement in a growth hormone deficient subject recovering from mild traumatic brain injury: A case report. Brain Inj (2010) 0.80
Cancer cachexia and anabolic interventions: a case report. J Cachexia Sarcopenia Muscle (2012) 0.80
Sequential monitoring of minimal residual disease in acute lymphoblastic leukemia: 7-year experience in a pediatric hematology/oncology unit. Leuk Lymphoma (2010) 0.79
Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73gamma in lung cancer. FEBS J (2010) 0.79
Up-regulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium-calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells. Endocrinology (2004) 0.79
Aerobic capacity and growth hormone deficiency after traumatic brain injury. J Clin Endocrinol Metab (2008) 0.79