PubRank

Ursula Klingmüller

Author PubWeight™ 50.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A mouse model for visualization and conditional mutations in the erythroid lineage. Blood 2004 2.41
2 The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest 2011 2.30
3 Covering a broad dynamic range: information processing at the erythropoietin receptor. Science 2010 1.65
4 Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood 2014 1.50
5 Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range. Mol Syst Biol 2011 1.45
6 Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions. Mol Syst Biol 2009 1.31
7 Lessons learned from quantitative dynamical modeling in systems biology. PLoS One 2013 1.28
8 Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood 2008 1.20
9 The glucocorticoid receptor controls hepatic dyslipidemia through Hes1. Cell Metab 2008 1.15
10 Computational processing and error reduction strategies for standardized quantitative data in biological networks. FEBS J 2005 1.13
11 The interface between self-assembling erythropoietin receptor transmembrane segments corresponds to a membrane-spanning leucine zipper. J Biol Chem 2003 1.08
12 The virtual liver: state of the art and future perspectives. Arch Toxicol 2014 1.05
13 Dynamic pathway modeling: feasibility analysis and optimal experimental design. Ann N Y Acad Sci 2007 1.04
14 Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding. J Biol Chem 2011 1.01
15 The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis. J Cell Biol 2013 1.01
16 Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells. Mol Biol Cell 2006 1.00
17 Effects of telomerase modulation in human hematopoietic progenitor cells. Stem Cells 2004 0.98
18 Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood 2013 0.94
19 Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics 2008 0.93
20 Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets. Cancer Res 2010 0.92
21 Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions. Bioessays 2012 0.92
22 Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation. BMC Bioinformatics 2010 0.91
23 Quenched substrates for live-cell labeling of SNAP-tagged fusion proteins with improved fluorescent background. Anal Chem 2010 0.91
24 Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration. Front Physiol 2012 0.89
25 Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling. FEBS J 2010 0.89
26 Standardizing experimental protocols. Curr Opin Biotechnol 2008 0.89
27 Targeted near-infrared imaging of the erythropoietin receptor in human lung cancer xenografts. J Nucl Med 2012 0.87
28 A rapidly reversible chemical dimerizer system to study lipid signaling in living cells. Angew Chem Int Ed Engl 2014 0.87
29 A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway. BMC Syst Biol 2008 0.86
30 An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes. FEBS J 2012 0.86
31 One-source peptide/phosphopeptide standards for accurate phosphorylation degree determination. Proteomics 2011 0.85
32 A functional green fluorescent protein-erythropoietin receptor despite physical separation of JAK2 binding site and tyrosine residues. J Biol Chem 2002 0.85
33 Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Mol Oncol 2008 0.84
34 Cellular ERK phospho-form profiles with conserved preference for a switch-like pattern. J Proteome Res 2012 0.83
35 Dynamics and feedback loops in the transforming growth factor β signaling pathway. Biophys Chem 2012 0.83
36 Vegf regulates embryonic erythroid development through Gata1 modulation. Blood 2010 0.83
37 Systems biology of JAK/STAT signalling. Essays Biochem 2008 0.82
38 The cytokine-inducible Scr homology domain-containing protein negatively regulates signaling by promoting apoptosis in erythroid progenitor cells. J Biol Chem 2002 0.82
39 Packing density of the erythropoietin receptor transmembrane domain correlates with amplification of biological responses. Biochemistry 2008 0.80
40 Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling. J Proteome Res 2014 0.80
41 In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems. BMC Syst Biol 2012 0.80
42 Model-based extension of high-throughput to high-content data. BMC Syst Biol 2010 0.79
43 Hepatocellular carcinoma: a systems biology perspective. Front Physiol 2013 0.79
44 Receptor dynamics in signaling. Adv Exp Med Biol 2012 0.78
45 Prognostic significance of erythropoietin in pancreatic adenocarcinoma. PLoS One 2011 0.78
46 Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cell Commun Signal 2012 0.78
47 Theoretical analysis of time-to-peak responses in biological reaction networks. Bull Math Biol 2010 0.77
48 T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes. Mol Syst Biol 2015 0.77
49 A Systems Biology Study on NFκB Signaling in Primary Mouse Hepatocytes. Front Physiol 2012 0.76
50 Excemplify: a flexible template based solution, parsing and managing data in spreadsheets for experimentalists. J Integr Bioinform 2013 0.75