Published in J Cancer Res Clin Oncol on April 23, 2009
The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway. Oncotarget (2014) 0.96
An efficient targeted drug delivery through apotransferrin loaded nanoparticles. PLoS One (2009) 0.95
Analysis of hepcidin expression: in situ hybridization and quantitative polymerase chain reaction from paraffin sections. World J Gastroenterol (2012) 0.83
Preparation and in vitro studies of MRI-specific superparamagnetic iron oxide antiGPC3 probe for hepatocellular carcinoma. Int J Nanomedicine (2012) 0.83
Efficacy, safety and anticancer activity of protein nanoparticle-based delivery of doxorubicin through intravenous administration in rats. PLoS One (2012) 0.82
Quantitative proteomic analysis in HCV-induced HCC reveals sets of proteins with potential significance for racial disparity. J Transl Med (2013) 0.81
Iron depletion enhances the effect of sorafenib in hepatocarcinoma. Cancer Biol Ther (2016) 0.79
Clodronate-superparamagnetic iron oxide-containing liposomes attenuate renal injury in rats with severe acute pancreatitis. J Zhejiang Univ Sci B (2014) 0.79
Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver. Toxicol Sci (2011) 0.78
Ligand-based targeted therapy: a novel strategy for hepatocellular carcinoma. Int J Nanomedicine (2016) 0.77
MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis. Oncotarget (2016) 0.75
Correlation of serum hepcidin levels with disease progression in hepatitis B virus-related disease assessed by nanopore film based assay. Sci Rep (2016) 0.75
Preoperative mean corpuscular hemoglobin affecting long-term outcomes of hepatectomized patients with hepatocellular carcinoma. Mol Clin Oncol (2015) 0.75
Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc (2008) 62.52
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (2004) 19.19
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem (2000) 8.52
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest (2002) 7.90
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A (2001) 5.77
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet (2003) 4.49
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet (2002) 4.19
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood (2002) 3.93
Iron homeostasis. Annu Rev Physiol (2007) 3.22
Anemia of inflammation: the cytokine-hepcidin link. J Clin Invest (2004) 2.25
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Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation. Blood (2007) 1.97
Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C. Mol Med (2007) 1.59
The iron metabolism of neoplastic cells: alterations that facilitate proliferation? Crit Rev Oncol Hematol (2002) 1.40
Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood (2005) 1.38
Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice. Blood Cells Mol Dis (2004) 1.25
Hepcidin is down-regulated in alcoholic liver injury: implications for the pathogenesis of alcoholic liver disease. Alcohol Clin Exp Res (2006) 1.17
Molecular characterization of a case of atransferrinemia. Blood (2000) 1.14
Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. J Clin Gastroenterol (2005) 1.10
Expression of hepcidin mRNA is uniformly suppressed in hepatocellular carcinoma. BMC Cancer (2008) 1.06
Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights. J Hepatol (2002) 1.04
Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients. Hepatology (1993) 1.03
Hepcidin is down-regulated in alcohol loading. Alcohol Clin Exp Res (2007) 1.01
Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am J Hum Genet (1993) 1.01
Hepatic iron metabolism. Semin Liver Dis (2005) 1.00
Expression of iron regulatory genes in a rat model of hepatocellular carcinoma. Liver Int (2006) 0.96
Hereditary hemochromatosis. Annu Rev Nutr (2006) 0.91
Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis? Lab Invest (2008) 0.80
Reduced expression of C/EBP alpha protein in hepatocellular carcinoma is associated with advanced tumor stage and shortened patient survival. J Cancer Res Clin Oncol (2008) 0.80
Modulation of KCNQ1 alternative splicing regulates cardiac IKs and action potential repolarization. Heart Rhythm (2013) 2.61
Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers. Carcinogenesis (2005) 2.31
Determinants of bilateral audiometric notches in noise-induced hearing loss. Laryngoscope (2013) 2.04
Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease. Cancer Biol Ther (2011) 1.72
5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells. Ann Neurol (2008) 1.60
Outcomes of hepatectomy for hepatolithiasis. World J Surg (2007) 1.54
DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. Biochem Biophys Res Commun (2010) 1.52
Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway. Evid Based Complement Alternat Med (2012) 1.47
Percutaneous absorption of inorganic lead compounds. AIHA J (Fairfax, Va) (2003) 1.43
Disturbance of circadian gene expression in hepatocellular carcinoma. Mol Carcinog (2008) 1.27
Does prenatal cadmium exposure affect fetal and child growth? Occup Environ Med (2010) 1.26
Abnormal expression of period 1 (PER1) in endometrial carcinoma. J Pathol (2005) 1.25
Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. Cancer Res (2007) 1.23
Toll-like receptor 4 gene C119A but not Asp299Gly polymorphism is associated with ischemic stroke among ethnic Chinese in Taiwan. Atherosclerosis (2005) 1.21
Helium-neon laser irradiation stimulates cell proliferation through photostimulatory effects in mitochondria. J Invest Dermatol (2007) 1.17
Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. Cancer Res (2011) 1.15
Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status. Ann Surg Oncol (2008) 1.13
Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers. Int J Mol Med (2004) 1.13
Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer. Cancer Res (2003) 1.12
In utero exposure to environmental lead and manganese and neurodevelopment at 2 years of age. Environ Res (2013) 1.10
A polymorphic -844T/C in FasL promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res (2011) 1.09
Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy. Int J Mol Sci (2013) 1.09
Sculpting skin appendages out of epidermal layers via temporally and spatially regulated apoptotic events. J Invest Dermatol (2004) 1.09
Multiphoton fluorescence and second harmonic generation imaging of the structural alterations in keratoconus ex vivo. Invest Ophthalmol Vis Sci (2006) 1.08
JunB gene expression is inactivated by methylation in chronic myeloid leukemia. Blood (2002) 1.07
Characterization of a familial case with primary erythromelalgia from Taiwan. J Neurol (2007) 1.05
Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer. Ann Surg Oncol (2010) 1.04
Arsenic promotes centrosome abnormalities and cell colony formation in p53 compromised human lung cells. Toxicol Appl Pharmacol (2007) 1.03
High-resolution melting: applications in genetic disorders. Clin Chim Acta (2012) 1.03
Fast simultaneous detection of K-RAS mutations in colorectal cancer. BMC Cancer (2009) 1.02
Association of RS2200733 but not RS10033464 on 4q25 with atrial fibrillation based on the recessive model in a Taiwanese population. Cardiology (2010) 1.01
Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3. Cancer Sci (2006) 1.01
MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells. Int J Mol Med (2012) 1.01
Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib. Cancer Res (2011) 1.01
Temporal change in bimanual interkeypress intervals and self-reported symptoms during continuous typing. J Occup Rehabil (2008) 1.01
ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations. PLoS One (2012) 0.99
Disturbance of circadian gene expression in breast cancer. Virchows Arch (2009) 0.99
Fenofibrate exhibits a high potential to suppress the formation of squamous cell carcinoma in an oral-specific 4-nitroquinoline 1-oxide/arecoline mouse model. Biochim Biophys Acta (2010) 0.98
Gender difference in the prognostic role of interleukin 6 in oral squamous cell carcinoma. PLoS One (2012) 0.97
Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol (2012) 0.97
Predicting health-related quality of life in patients with low back pain. Spine (Phila Pa 1976) (2005) 0.97
Effect of TIMP-1 and MMP in pterygium invasion. Invest Ophthalmol Vis Sci (2010) 0.97
Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia. Br J Haematol (2003) 0.96
Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major. Hemoglobin (2006) 0.96
Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer. BMC Cancer (2006) 0.96
The effect of hydroxyurea in spinal muscular atrophy cells and patients. J Neurol Sci (2007) 0.96
Novel heteroplasmic frameshift and missense somatic mitochondrial DNA mutations in oral cancer of betel quid chewers. Genes Chromosomes Cancer (2003) 0.96
Arsenic induces human keratinocyte apoptosis by the FAS/FAS ligand pathway, which correlates with alterations in nuclear factor-kappa B and activator protein-1 activity. J Invest Dermatol (2004) 0.96
A polymorphism of the ORAI1 gene is associated with the risk and recurrence of calcium nephrolithiasis. J Urol (2011) 0.96
Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancers. Am J Pathol (2011) 0.95
Low concentrations of arsenic induce vascular endothelial growth factor and nitric oxide release and stimulate angiogenesis in vitro. Chem Res Toxicol (2003) 0.95
Effect of gestational smoke exposure on atopic dermatitis in the offspring. Pediatr Allergy Immunol (2008) 0.94
Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population. Clin Chim Acta (2012) 0.94
High expression of interleukin 10 might predict poor prognosis in early stage oral squamous cell carcinoma patients. Clin Chim Acta (2012) 0.94
The mechanisms of action of Tianhua(™) on antitumor activity in lung cancer cells. Pharm Biol (2010) 0.94
Rapid identification of HBB gene mutations by high-resolution melting analysis. Clin Biochem (2009) 0.94
Possible association between nickel and chromium and oral cancer: a case-control study in central Taiwan. Sci Total Environ (2010) 0.93
Overexpression of Thy1/CD90 in human hepatocellular carcinoma is associated with HBV infection and poor prognosis. Acta Histochem (2011) 0.93
Synthesis and biological evaluation of thiobenzanilides as anticancer agents. Bioorg Med Chem (2008) 0.93
Cardiopulmonary toxicity of pulmonary exposure to occupationally relevant zinc oxide nanoparticles. Nanotoxicology (2013) 0.93
A recurrent ITGA9 missense mutation in human fetuses with severe chylothorax: possible correlation with poor response to fetal therapy. Prenat Diagn (2008) 0.92
Promoter CpG methylation of caveolin-1 in sporadic colorectal cancer. Anticancer Res (2004) 0.92
Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. Nucleic Acids Res (2013) 0.92
Elucidating the underlying causes of oral cancer through spatial clustering in high-risk areas of Taiwan with a distinct gender ratio of incidence. Geospat Health (2010) 0.92
Acupuncture, electrostimulation, and reflex therapy in dermatology. Dermatol Ther (2003) 0.92
Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis. Chem Biol Interact (2010) 0.91
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer. Clin Chim Acta (2006) 0.91
The correlation between CpG methylation on promoter and protein expression of E-cadherin in oral squamous cell carcinoma. Anticancer Res (2003) 0.91
Biomarkers for itch and disease severity in atopic dermatitis. Curr Probl Dermatol (2011) 0.91
Vorinostat, SAHA, represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells. J Cell Biochem (2011) 0.90
The change of beta-adrenergic system after cessation of lead exposure. Toxicology (2005) 0.90
Effect of linear polarized light irradiation near the stellate ganglion in skin blood flow of fingers in patients with progressive systemic sclerosis. Photomed Laser Surg (2006) 0.90
Sodium arsenite-induced DAPK promoter hypermethylation and autophagy via ERK1/2 phosphorylation in human uroepithelial cells. Chem Biol Interact (2009) 0.90
Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features. Oncol Rep (2004) 0.90
The Taiwanese Dermatological Association and the Taiwanese Society for Investigative Dermatology: brief history and current status. J Invest Dermatol (2009) 0.90
ALPK1 genetic regulation and risk in relation to gout. Int J Epidemiol (2013) 0.90
Clinical implications of deregulated CDK4 and Cyclin D1 expression in patients with human hepatocellular carcinoma. Med Oncol (2013) 0.90
Prevalence of adult atopic dermatitis among nursing staff in a Taiwanese medical center: a pilot study on validation of diagnostic questionnaires. J Am Acad Dermatol (2009) 0.90
Differential impact of IL-10 expression on survival and relapse between HPV16-positive and -negative oral squamous cell carcinomas. PLoS One (2012) 0.90
Detection of the JAK2 V617F missense mutation by high resolution melting analysis and its validation. Clin Chim Acta (2009) 0.90
Heat shock induces apoptosis through reactive oxygen species involving mitochondrial and death receptor pathways in corneal cells. Exp Eye Res (2011) 0.90
Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells. Toxicology (2008) 0.89
GMI, a Ganoderma immunomodulatory protein, down-regulates tumor necrosis factor α-induced expression of matrix metalloproteinase 9 via NF-κB pathway in human alveolar epithelial A549 cells. J Agric Food Chem (2010) 0.89
Antineutrophil cytoplasmic antibody-positive cutaneous leukocytoclastic vasculitis associated with propylthiouracil therapy. Arch Dermatol (2006) 0.89
Glutathione S-transferase T1 deletion is a risk factor for developing end-stage renal disease in diabetic patients. Int J Mol Med (2004) 0.89
Somatic mitochondrial DNA mutations in oral cancer of betel quid chewers. Ann N Y Acad Sci (2004) 0.89
Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: roles of cyclic AMP and p38 mitogen-activated protein kinase. World J Gastroenterol (2005) 0.89
Plasma nuclear DNA and mitochondrial DNA as prognostic markers in corrosive injury patients. Dig Surg (2008) 0.89