Published in Microbiology on April 23, 2009
Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep (2009) 3.74
Signals and regulators that govern Streptomyces development. FEMS Microbiol Rev (2011) 1.50
Triggers and cues that activate antibiotic production by actinomycetes. J Ind Microbiol Biotechnol (2013) 1.14
Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose. Appl Environ Microbiol (2014) 0.94
Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2). Microb Biotechnol (2010) 0.93
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. J Biol Chem (2011) 0.92
Biosynthesis and regulation of grisemycin, a new member of the linaridin family of ribosomally synthesized peptides produced by Streptomyces griseus IFO 13350. J Bacteriol (2011) 0.92
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biol (2013) 0.87
ArgR of Streptomyces coelicolor is a versatile regulator. PLoS One (2012) 0.86
Repression of antibiotic downregulator WblA by AdpA in Streptomyces coelicolor. Appl Environ Microbiol (2013) 0.85
WblAch, a pivotal activator of natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis L10, is positively regulated by AdpAch. Appl Environ Microbiol (2014) 0.80
Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes. PLoS One (2012) 0.79
Identified members of the Streptomyces lividans AdpA regulon involved in differentiation and secondary metabolism. BMC Microbiol (2014) 0.78
Structural biological study of self-resistance determinants in antibiotic-producing actinomycetes. J Antibiot (Tokyo) (2015) 0.75
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol (2006) 5.46
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol (2007) 4.95
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350. J Bacteriol (2008) 4.59
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J (2002) 4.28
FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res (2002) 2.90
DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus. Mol Microbiol (2004) 2.00
AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Biosci Biotechnol Biochem (2005) 1.80
Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. Chem Biol (2009) 1.48
Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster. Appl Environ Microbiol (2003) 1.45
Crystal structure of a gamma-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2). J Mol Biol (2004) 1.44
Signalling early developmental events in two highly diverged Streptomyces species. Mol Microbiol (2003) 1.38
Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli. Chem Biol (2007) 1.37
Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii. Proc Natl Acad Sci U S A (2006) 1.35
Identification of SAP155 as the target of GEX1A (Herboxidiene), an antitumor natural product. ACS Chem Biol (2011) 1.34
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae. DNA Res (2010) 1.32
Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa. J Biol Chem (2007) 1.31
GEX1 compounds, novel antitumor antibiotics related to herboxidiene, produced by Streptomyces sp. II. The effects on cell cycle progression and gene expression. J Antibiot (Tokyo) (2002) 1.27
pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast. Yeast (2004) 1.26
Biosynthesis of gamma-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces. Proc Natl Acad Sci U S A (2007) 1.24
Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus. J Biol Chem (2008) 1.23
Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes. Biosci Biotechnol Biochem (2004) 1.23
Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus. J Bacteriol (2003) 1.14
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes. J Biol Chem (2006) 1.11
Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus. J Bacteriol (2002) 1.11
Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. Appl Microbiol Biotechnol (2005) 1.10
Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression. J Biochem (2007) 1.10
Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus. J Bacteriol (2005) 1.09
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. J Biol Chem (2006) 1.08
Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus. J Biol Chem (2001) 1.08
A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone. J Biol Chem (2005) 1.07
Global analysis of gel mobility of proteins and its use in target identification. J Biol Chem (2008) 1.07
Cinnamate:coenzyme A ligase from the filamentous bacterium streptomyces coelicolor A3(2). J Bacteriol (2003) 1.06
AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs. J Mol Biol (2007) 1.05
ATP-binding cassette transport system involved in regulation of morphological differentiation in response to glucose in Streptomyces griseus. J Bacteriol (2002) 1.05
Evolution of gamma-butyrolactone synthases and receptors in Streptomyces. Environ Microbiol (2007) 1.04
Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. J Biol Chem (2009) 1.04
Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis. Proc Natl Acad Sci U S A (2008) 1.04
afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2). Mol Microbiol (2002) 1.04
CebR as a master regulator for cellulose/cellooligosaccharide catabolism affects morphological development in Streptomyces griseus. J Bacteriol (2009) 1.04
Identification and gene disruption of small noncoding RNAs in Streptomyces griseus. J Bacteriol (2009) 1.03
In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa. J Biol Chem (2007) 1.03
amfR, an essential gene for aerial mycelium formation, is a member of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus. Mol Microbiol (2003) 1.02
AmfS, an extracellular peptidic morphogen in Streptomyces griseus. J Bacteriol (2002) 1.01
14-3-3 regulates the nuclear import of class IIa histone deacetylases. Biochem Biophys Res Commun (2008) 1.00
Conditionally positive effect of the TetR-family transcriptional regulator AtrA on streptomycin production by Streptomyces griseus. Microbiology (2008) 1.00
A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides. J Biol Chem (2005) 1.00
Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus. Mol Microbiol (2011) 0.97
Dynamic changes in the extracellular proteome caused by absence of a pleiotropic regulator AdpA in Streptomyces griseus. Mol Microbiol (2009) 0.97
Phosphorylation of AfsR by multiple serine/threonine kinases in Streptomyces coelicolor A3(2). Gene (2004) 0.97
Putative ABC transporter responsible for acetic acid resistance in Acetobacter aceti. Appl Environ Microbiol (2006) 0.96
Genome mining reveals two novel bacterial sesquiterpene cyclases: (-)-germacradien-4-ol and (-)-epi-α-bisabolol synthases from Streptomyces citricolor. Chembiochem (2011) 0.96
Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products. Cancer Sci (2005) 0.96
Deprogrammed sporulation in Streptomyces. FEMS Microbiol Lett (2002) 0.95
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis. J Bacteriol (2009) 0.95
Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus. J Mol Biol (2005) 0.95
Combinatorial biosynthesis of flavones and flavonols in Escherichia coli. Appl Microbiol Biotechnol (2005) 0.95
Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus. J Bacteriol (2005) 0.94
Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells. Biochem Biophys Res Commun (2008) 0.93
A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus. J Bacteriol (2004) 0.93
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. J Biol Chem (2011) 0.92
Structures of grixazone A and B, A-factor-dependent yellow pigments produced under phosphate depletion by Streptomyces griseus. J Antibiot (Tokyo) (2004) 0.92
Enhanced expression of aconitase raises acetic acid resistance in Acetobacter aceti. FEMS Microbiol Lett (2004) 0.92
Identification and characterization of multiple curcumin synthases from the herb Curcuma longa. FEBS Lett (2009) 0.92
A copper-containing oxidase catalyzes C-nitrosation in nitrosobenzamide biosynthesis. Nat Chem Biol (2010) 0.92
Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus. J Bacteriol (2005) 0.91
Fatty acyl-AMP ligase involvement in the production of alkylresorcylic acid by a Myxococcus xanthus type III polyketide synthase. Chembiochem (2011) 0.90
A-factor and phosphate depletion signals are transmitted to the grixazone biosynthesis genes via the pathway-specific transcriptional activator GriR. J Bacteriol (2007) 0.90