Published in J Biol Chem on December 17, 2006
Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation. Nucleic Acids Res (2009) 3.44
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Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
The tale of protein lysine acetylation in the cytoplasm. J Biomed Biotechnol (2010) 1.44
Myelin proteomics: molecular anatomy of an insulating sheath. Mol Neurobiol (2009) 1.40
Pre-mRNA 3'-end processing complex assembly and function. Wiley Interdiscip Rev RNA (2010) 1.30
Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function. Genes Dev (2008) 1.19
SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Proc Natl Acad Sci U S A (2010) 1.19
PARP1 represses PAP and inhibits polyadenylation during heat shock. Mol Cell (2012) 1.05
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Metabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylation. EMBO Rep (2007) 0.94
Finishing touches: post-translational modification of protein factors involved in mammalian pre-mRNA 3' end formation. Int J Biochem Cell Biol (2008) 0.92
Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry (2013) 0.89
Nuclear sphingolipid metabolism. Annu Rev Physiol (2011) 0.89
Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. Mol Cell Biol (2015) 0.88
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Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA (2010) 0.87
In cortical neurons HDAC3 activity suppresses RD4-dependent SMRT export. PLoS One (2011) 0.83
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Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells. PLoS One (2011) 0.80
Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway. Mol Cell Biol (2015) 0.77
The 25 kDa subunit of cleavage factor Im Is a RNA-binding protein that interacts with the poly(A) polymerase in Entamoeba histolytica. PLoS One (2013) 0.76
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CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function. RNA (2016) 0.75
Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking. Mol Cell Proteomics (2016) 0.75
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HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell (2005) 6.00
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol (2006) 5.46
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol (2007) 4.95
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350. J Bacteriol (2008) 4.59
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J (2002) 4.28
RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell (2013) 3.64
Ureteral stent encrustation, incrustation, and coloring: morbidity related to indwelling times. J Endourol (2011) 3.29
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. Nat Cell Biol (2004) 3.14
FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res (2002) 2.90
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol (2002) 2.35
E3 ubiquitin ligase that recognizes sugar chains. Nature (2002) 2.17
The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J Biol Chem (2001) 2.16
Bone morphogenetic protein-2 stimulates Runx2 acetylation. J Biol Chem (2006) 2.15
Ureteroscopy assisted retrograde nephrostomy: a new technique for percutaneous nephrolithotomy (PCNL). BJU Int (2011) 2.14
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export. J Biol Chem (2002) 2.12
DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus. Mol Microbiol (2004) 2.00
Total synthesis of (+)-chaetocin and its analogues: their histone methyltransferase G9a inhibitory activity. J Am Chem Soc (2010) 1.80
AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Biosci Biotechnol Biochem (2005) 1.80
Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene (2005) 1.79
VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma. J Natl Cancer Inst (2002) 1.75
Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. Chem Biol (2009) 1.70
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. Differentiation (2005) 1.68
Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors. Chem Biol (2011) 1.65
Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: relationship to clinicopathological parameters. Genes Chromosomes Cancer (2002) 1.52
PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation. EMBO J (2003) 1.50
Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor. Oncogene (2003) 1.50
Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1. EMBO J (2004) 1.49
Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. Chem Biol (2009) 1.48
Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies. Proteomics (2005) 1.46
Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster. Appl Environ Microbiol (2003) 1.45
Crystal structure of a gamma-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2). J Mol Biol (2004) 1.44
Translational control of cell division by Elongator. Cell Rep (2012) 1.41
HDAC6 a new cellular stress surveillance factor. Cell Cycle (2007) 1.40
Signalling early developmental events in two highly diverged Streptomyces species. Mol Microbiol (2003) 1.38
Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli. Chem Biol (2007) 1.37
Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. Exp Cell Res (2002) 1.36
Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii. Proc Natl Acad Sci U S A (2006) 1.35
Identification of SAP155 as the target of GEX1A (Herboxidiene), an antitumor natural product. ACS Chem Biol (2011) 1.34
13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit. Bioorg Med Chem (2005) 1.32
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae. DNA Res (2010) 1.32
Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa. J Biol Chem (2007) 1.31
A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25. Mol Biol Cell (2006) 1.31
GEX1 compounds, novel antitumor antibiotics related to herboxidiene, produced by Streptomyces sp. II. The effects on cell cycle progression and gene expression. J Antibiot (Tokyo) (2002) 1.27
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun (2012) 1.27
pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast. Yeast (2004) 1.26
Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation. J Cell Biol (2011) 1.25
Subtype selective substrates for histone deacetylases. J Med Chem (2004) 1.25
Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner. J Immunol (2002) 1.25
Biosynthesis of gamma-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces. Proc Natl Acad Sci U S A (2007) 1.24
Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus. J Biol Chem (2008) 1.23
Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes. Biosci Biotechnol Biochem (2004) 1.23
Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era. Cancer Sci (2009) 1.22
Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem (2007) 1.22
Nucleo-cytoplasmic transport of proteins as a target for therapeutic drugs. Curr Med Chem (2003) 1.21
Real-time imaging of histone H4 hyperacetylation in living cells. Proc Natl Acad Sci U S A (2009) 1.20
Erasers of histone acetylation: the histone deacetylase enzymes. Cold Spring Harb Perspect Biol (2014) 1.18
Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin. Nat Struct Mol Biol (2008) 1.18
Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression. J Biol Chem (2002) 1.15
Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes. Nat Struct Mol Biol (2011) 1.15
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. Arterioscler Thromb Vasc Biol (2006) 1.14
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses. EMBO J (2005) 1.14
Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus. J Bacteriol (2003) 1.14
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes. J Biol Chem (2006) 1.11
Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus. J Bacteriol (2002) 1.11
Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains. Mol Cell (2013) 1.10
Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription. Genes Cells (2006) 1.10
Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. Appl Microbiol Biotechnol (2005) 1.10
Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression. J Biochem (2007) 1.10
Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus. J Bacteriol (2005) 1.09
The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor. J Med Chem (2007) 1.09
Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication. Nucleic Acids Res (2008) 1.08
Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus. J Biol Chem (2001) 1.08
A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone. J Biol Chem (2005) 1.07
Global analysis of gel mobility of proteins and its use in target identification. J Biol Chem (2008) 1.07
Cinnamate:coenzyme A ligase from the filamentous bacterium streptomyces coelicolor A3(2). J Bacteriol (2003) 1.06
AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs. J Mol Biol (2007) 1.05
ATP-binding cassette transport system involved in regulation of morphological differentiation in response to glucose in Streptomyces griseus. J Bacteriol (2002) 1.05
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7. J Biol Chem (2003) 1.05
Evolution of gamma-butyrolactone synthases and receptors in Streptomyces. Environ Microbiol (2007) 1.04
Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. J Biol Chem (2009) 1.04
Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis. Proc Natl Acad Sci U S A (2008) 1.04
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. J Med Chem (2006) 1.04
afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2). Mol Microbiol (2002) 1.04
CebR as a master regulator for cellulose/cellooligosaccharide catabolism affects morphological development in Streptomyces griseus. J Bacteriol (2009) 1.04
Identification and gene disruption of small noncoding RNAs in Streptomyces griseus. J Bacteriol (2009) 1.03
In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa. J Biol Chem (2007) 1.03
Splicing in oncogenesis and tumor suppression. Cancer Sci (2012) 1.03