Published in Infect Immun on April 27, 2009
In vivo expression technology identifies a novel virulence factor critical for Borrelia burgdorferi persistence in mice. PLoS Pathog (2013) 1.49
Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity. PLoS One (2012) 1.19
Inactivation of bb0184, which encodes carbon storage regulator A, represses the infectivity of Borrelia burgdorferi. Infect Immun (2010) 1.05
Carbon storage regulator A (CsrA(Bb)) is a repressor of Borrelia burgdorferi flagellin protein FlaB. Mol Microbiol (2011) 1.02
Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment. Mol Microbiol (2010) 1.01
Outer surface protein C is a dissemination-facilitating factor of Borrelia burgdorferi during mammalian infection. PLoS One (2010) 0.99
Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. PLoS One (2012) 0.98
Variable VlsE is critical for host reinfection by the Lyme disease spirochete. PLoS One (2013) 0.96
Lipoprotein succession in Borrelia burgdorferi: similar but distinct roles for OspC and VlsE at different stages of mammalian infection. Mol Microbiol (2013) 0.95
Study of the response regulator Rrp1 reveals its regulatory role in chitobiose utilization and virulence of Borrelia burgdorferi. Infect Immun (2013) 0.91
Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin. Infect Immun (2010) 0.89
Transposon mutagenesis as an approach to improved understanding of Borrelia pathogenesis and biology. Front Cell Infect Microbiol (2014) 0.89
Regulation of the virulence determinant OspC by bbd18 on linear plasmid lp17 of Borrelia burgdorferi. J Bacteriol (2011) 0.85
vls Antigenic Variation Systems of Lyme Disease Borrelia: Eluding Host Immunity through both Random, Segmental Gene Conversion and Framework Heterogeneity. Microbiol Spectr (2014) 0.84
Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi. MBio (2014) 0.83
Bacterial heterogeneity is a requirement for host superinfection by the Lyme disease spirochete. Infect Immun (2014) 0.82
Borrelia burgdorferi resistance to a major skin antimicrobial peptide is independent of outer surface lipoprotein content. Antimicrob Agents Chemother (2009) 0.80
Raft-like membrane domains in pathogenic microorganisms. Curr Top Membr (2015) 0.78
In Vivo Imaging Demonstrates That Borrelia burgdorferi ospC Is Uniquely Expressed Temporally and Spatially throughout Experimental Infection. PLoS One (2016) 0.76
Virulence of the Lyme disease spirochete before and after the tick bloodmeal: a quantitative assessment. Parasit Vectors (2016) 0.76
Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc Natl Acad Sci U S A (1995) 9.93
Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell (1997) 6.36
Lyme borreliosis in selected strains and ages of laboratory mice. J Infect Dis (1990) 5.95
Immunochemical and immunological analysis of European Borrelia burgdorferi strains. Zentralbl Bakteriol Mikrobiol Hyg A (1986) 5.06
Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc Natl Acad Sci U S A (2000) 4.81
Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice. J Clin Microbiol (2000) 4.71
An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res (2004) 3.96
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals. Proc Natl Acad Sci U S A (2004) 3.84
Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background. Infect Immun (2002) 3.65
Electrotransformation of the spirochete Borrelia burgdorferi. Methods Mol Biol (1995) 3.50
A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest (1998) 3.41
Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans. Infect Immun (1999) 3.41
OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest (2004) 3.38
Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks. Proc Natl Acad Sci U S A (2001) 3.28
Characterization of Borrelia burgdorferi strains isolated from Ixodes pacificus ticks in California. J Clin Microbiol (1987) 2.89
Efficient targeted mutagenesis in Borrelia burgdorferi. J Bacteriol (2000) 2.89
Kinetics and in vivo induction of genetic variation of vlsE in Borrelia burgdorferi. Infect Immun (1998) 2.56
Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection. Infect Immun (2006) 2.54
Molecular adaptation of Borrelia burgdorferi in the murine host. J Exp Med (2002) 2.49
Rapid and sensitive quantification of Borrelia burgdorferi-infected mouse tissues by continuous fluorescent monitoring of PCR. J Clin Microbiol (1999) 2.39
An immune evasion mechanism for spirochetal persistence in Lyme borreliosis. J Exp Med (2002) 2.25
Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences. Mol Microbiol (2008) 2.23
Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice. Infect Immun (1998) 2.12
BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype. Infect Immun (2004) 2.08
New antibiotic resistance cassettes suitable for genetic studies in Borrelia burgdorferi. J Mol Microbiol Biotechnol (2003) 2.07
Distribution and molecular analysis of Lyme disease spirochetes, Borrelia burgdorferi, isolated from ticks throughout California. J Clin Microbiol (1993) 2.03
Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses. Infect Immun (2004) 1.82
Borrelia burgdorferi population dynamics and prototype gene expression during infection of immunocompetent and immunodeficient mice. Infect Immun (2003) 1.82
The propensity of different Borrelia burgdorferi sensu stricto genotypes to cause disseminated infections in humans. Am J Trop Med Hyg (2008) 1.82
The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi. Mol Microbiol (2007) 1.66
Crystal structure of Lyme disease variable surface antigen VlsE of Borrelia burgdorferi. J Biol Chem (2002) 1.62
Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response. Infect Immun (2005) 1.55
Delineating the requirement for the Borrelia burgdorferi virulence factor OspC in the mammalian host. Infect Immun (2006) 1.55
Serodiagnosis of Louse-Borne relapsing fever with glycerophosphodiester phosphodiesterase (GlpQ) from Borrelia recurrentis. J Clin Microbiol (2000) 1.55
Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi. EMBO J (2001) 1.54
Analysis of antibody response to invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi. Infect Immun (1999) 1.53
Immune evasion by tickborne and host-adapted Borrelia burgdorferi. J Infect Dis (1998) 1.52
Rapid clearance of Lyme disease spirochetes lacking OspC from skin. Infect Immun (2006) 1.51
Borrelia burgdorferi ospC heterogeneity among human and murine isolates from a defined region of northern Maryland and southern Pennsylvania: lack of correlation with invasive and noninvasive genotypes. J Clin Microbiol (2005) 1.46
Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi. J Biol Chem (2001) 1.42
Temporal analysis of the antigenic composition of Borrelia burgdorferi during infection in rabbit skin. Infect Immun (2004) 1.42
Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi. Mol Microbiol (2007) 1.33
Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice. Infect Immun (1993) 1.31
Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi. Mol Microbiol (2007) 1.29
Constitutive expression of outer surface protein C diminishes the ability of Borrelia burgdorferi to evade specific humoral immunity. Infect Immun (2006) 1.28
Detailed analysis of sequence changes occurring during vlsE antigenic variation in the mouse model of Borrelia burgdorferi infection. PLoS Pathog (2009) 1.24
Borrelia burgdorferi adhesins identified using in vivo phage display. Mol Microbiol (2007) 1.17
Host-adapted Borrelia burgdorferi in mice expresses OspA during inflammation. Infect Immun (2003) 1.13
Borrelia burgdorferi sensu stricto invasiveness is correlated with OspC-plasminogen affinity. Microbes Infect (2006) 1.12
Nitric oxide production during murine Lyme disease: lack of involvement in host resistance or pathology. Infect Immun (1995) 1.11
Complementation of a Borrelia afzelii OspC mutant highlights the crucial role of OspC for dissemination of Borrelia afzelii in Ixodes ricinus. Int J Med Microbiol (2007) 1.06
Specificity of infection-induced immunity among Borrelia burgdorferi sensu lato species. Infect Immun (1999) 1.05
Increased expression of Borrelia burgdorferi vlsE in response to human endothelial cell membranes. Mol Microbiol (2001) 1.03
The long strange trip of Borrelia burgdorferi outer-surface protein C. Mol Microbiol (2008) 1.00
Transcriptional regulation of the Borrelia burgdorferi antigenically variable VlsE surface protein. J Bacteriol (2006) 0.96
The failure of immune response evasion by linear plasmid 28-1-deficient Borrelia burgdorferi is attributable to persistent expression of an outer surface protein. Infect Immun (2008) 0.93
Abrogation of ospAB constitutively activates the Rrp2-RpoN-RpoS pathway (sigmaN-sigmaS cascade) in Borrelia burgdorferi. Mol Microbiol (2008) 0.93
Reciprocal expression of ospA and ospC in single cells of Borrelia burgdorferi. J Bacteriol (2008) 0.91
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals. Proc Natl Acad Sci U S A (2004) 3.84
Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection. Infect Immun (2006) 2.54
Borrelia burgdorferi sigma54 is required for mammalian infection and vector transmission but not for tick colonization. Proc Natl Acad Sci U S A (2005) 2.41
New antibiotic resistance cassettes suitable for genetic studies in Borrelia burgdorferi. J Mol Microbiol Biotechnol (2003) 2.07
The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi. Mol Microbiol (2007) 1.66
Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle. Infect Immun (2004) 1.55
Delineating the requirement for the Borrelia burgdorferi virulence factor OspC in the mammalian host. Infect Immun (2006) 1.55
Rapid clearance of Lyme disease spirochetes lacking OspC from skin. Infect Immun (2006) 1.51
A previously uncharacterized role for small protein B (SmpB) in transfer messenger RNA-mediated trans-translation. Proc Natl Acad Sci U S A (2005) 1.50
In vivo expression technology identifies a novel virulence factor critical for Borrelia burgdorferi persistence in mice. PLoS Pathog (2013) 1.49
Genome-wide transposon mutagenesis of Borrelia burgdorferi for identification of phenotypic mutants. Appl Environ Microbiol (2004) 1.42
Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level. Infect Immun (2003) 1.40
Biology of infection with Borrelia burgdorferi. Infect Dis Clin North Am (2008) 1.35
Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi. Mol Microbiol (2007) 1.29
Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector. Infect Immun (2008) 1.21
GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle. J Bacteriol (2009) 1.20
The plasmids of Borrelia burgdorferi: essential genetic elements of a pathogen. Plasmid (2004) 1.18
Defining plasmids required by Borrelia burgdorferi for colonization of tick vector Ixodes scapularis (Acari: Ixodidae). J Med Entomol (2005) 1.12
A tightly regulated surface protein of Borrelia burgdorferi is not essential to the mouse-tick infectious cycle. Infect Immun (2008) 1.10
Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies. Infect Immun (2005) 1.09
Identification of potential virulence determinants by Himar1 transposition of infectious Borrelia burgdorferi B31. Infect Immun (2006) 1.08
Defining the plasmid-borne restriction-modification systems of the Lyme disease spirochete Borrelia burgdorferi. J Bacteriol (2010) 1.06
Differential telomere processing by Borrelia telomere resolvases in vitro but not in vivo. J Bacteriol (2006) 1.04
Motility is crucial for the infectious life cycle of Borrelia burgdorferi. Infect Immun (2013) 1.01
Cross-species surface display of functional spirochetal lipoproteins by recombinant Borrelia burgdorferi. Infect Immun (2004) 0.99
The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. Mol Microbiol (2012) 0.97
Lipoprotein succession in Borrelia burgdorferi: similar but distinct roles for OspC and VlsE at different stages of mammalian infection. Mol Microbiol (2013) 0.95
Competitive advantage of Borrelia burgdorferi with outer surface protein BBA03 during tick-mediated infection of the mammalian host. Infect Immun (2012) 0.95
Transposon mutagenesis of the lyme disease agent Borrelia burgdorferi. Methods Mol Biol (2008) 0.94
Use of the Cre-lox recombination system to investigate the lp54 gene requirement in the infectious cycle of Borrelia burgdorferi. Infect Immun (2010) 0.93
Characterization of the Bat proteins in the oxidative stress response of Leptospira biflexa. BMC Microbiol (2012) 0.90
Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage. Mol Microbiol (2009) 0.88
Borrelia burgdorferi linear plasmid 38 is dispensable for completion of the mouse-tick infectious cycle. Infect Immun (2011) 0.87
Regulation of the virulence determinant OspC by bbd18 on linear plasmid lp17 of Borrelia burgdorferi. J Bacteriol (2011) 0.85
Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA. Microbiology (2011) 0.85
Active and accurate trans-translation requires distinct determinants in the C-terminal tail of SmpB protein and the mRNA-like domain of transfer messenger RNA (tmRNA). J Biol Chem (2013) 0.84
Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection. Infect Immun (2012) 0.84
Relapsing fever spirochaetes produce a serine protease that provides resistance to oxidative stress and killing by neutrophils. Mol Microbiol (2006) 0.83
Borrelia burgdorferi resistance to a major skin antimicrobial peptide is independent of outer surface lipoprotein content. Antimicrob Agents Chemother (2009) 0.80
Requirements for Borrelia burgdorferi plasmid maintenance. Plasmid (2012) 0.80
lacZ reporter system for use in Borrelia burgdorferi. Appl Environ Microbiol (2010) 0.78
Borrelia burgdorferi linear plasmid 28-3 confers a selective advantage in an experimental mouse-tick infection model. Infect Immun (2013) 0.77
Regulatory protein BBD18 of the lyme disease spirochete: essential role during tick acquisition? MBio (2014) 0.77
Correction: In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in Mice. PLoS Pathog (2014) 0.75