Published in Am J Trop Med Hyg on May 01, 2008
Differentiation of reinfection from relapse in recurrent Lyme disease. N Engl J Med (2012) 3.79
Borrelia burgdorferi genotype predicts the capacity for hematogenous dissemination during early Lyme disease. J Infect Dis (2008) 2.26
Phylogeography of Borrelia burgdorferi in the eastern United States reflects multiple independent Lyme disease emergence events. Proc Natl Acad Sci U S A (2009) 1.71
Climate and tick seasonality are predictors of Borrelia burgdorferi genotype distribution. Appl Environ Microbiol (2009) 1.64
Evolution and distribution of the ospC Gene, a transferable serotype determinant of Borrelia burgdorferi. MBio (2010) 1.55
Delineating Anaplasma phagocytophilum ecotypes in coexisting, discrete enzootic cycles. Emerg Infect Dis (2009) 1.40
Geographic variation in the relationship between human Lyme disease incidence and density of infected host-seeking Ixodes scapularis nymphs in the Eastern United States. Am J Trop Med Hyg (2012) 1.34
Investigation of genotypes of Borrelia burgdorferi in Ixodes scapularis ticks collected during surveillance in Canada. Appl Environ Microbiol (2011) 1.32
Geographic differences in genetic locus linkages for Borrelia burgdorferi. Emerg Infect Dis (2010) 1.26
Genetic diversity of Borrelia burgdorferi and detection of B. bissettii-like DNA in serum of north-coastal California residents. J Clin Microbiol (2010) 1.24
Borrelia burgdorferi RST1 (OspC type A) genotype is associated with greater inflammation and more severe Lyme disease. Am J Pathol (2011) 1.21
Genetics of Borrelia burgdorferi. Annu Rev Genet (2012) 1.21
Population structure of the lyme borreliosis spirochete Borrelia burgdorferi in the western black-legged tick (Ixodes pacificus) in Northern California. Appl Environ Microbiol (2009) 1.18
Uncoordinated phylogeography of Borrelia burgdorferi and its tick vector, Ixodes scapularis. Evolution (2010) 1.15
Evolution of northeastern and midwestern Borrelia burgdorferi, United States. Emerg Infect Dis (2010) 1.12
Multilocus sequence typing of Borrelia burgdorferi suggests existence of lineages with differential pathogenic properties in humans. PLoS One (2013) 1.07
Allelic variation of the Lyme disease spirochete adhesin DbpA influences spirochetal binding to decorin, dermatan sulfate, and mammalian cells. Infect Immun (2011) 1.06
Experimental infections of the reservoir species Peromyscus leucopus with diverse strains of Borrelia burgdorferi, a Lyme disease agent. MBio (2012) 1.04
Effect of Borrelia burgdorferi genotype on the sensitivity of C6 and 2-tier testing in North American patients with culture-confirmed Lyme disease. Clin Infect Dis (2008) 1.03
Biodiversity of Borrelia burgdorferi strains in tissues of Lyme disease patients. PLoS One (2011) 1.00
OspC is potent plasminogen receptor on surface of Borrelia burgdorferi. J Biol Chem (2012) 1.00
OspC-independent infection and dissemination by host-adapted Borrelia burgdorferi. Infect Immun (2009) 1.00
Pervasive recombination and sympatric genome diversification driven by frequency-dependent selection in Borrelia burgdorferi, the Lyme disease bacterium. Genetics (2011) 0.97
Competitive advantage of Borrelia burgdorferi with outer surface protein BBA03 during tick-mediated infection of the mammalian host. Infect Immun (2012) 0.95
Ability to cause erythema migrans differs between Borrelia burgdorferi sensu lato isolates. Parasit Vectors (2013) 0.93
Comprehensive seroprofiling of sixteen B. burgdorferi OspC: implications for Lyme disease diagnostics design. Clin Immunol (2009) 0.92
Detection of Borrelia burgdorferi sensu stricto ospC alleles associated with human lyme borreliosis worldwide in non-human-biting tick Ixodes affinis and rodent hosts in Southeastern United States. Appl Environ Microbiol (2012) 0.92
First arrived takes all: inhibitory priority effects dominate competition between co-infecting Borrelia burgdorferi strains. BMC Microbiol (2015) 0.90
Occurrence and transmission efficiencies of Borrelia burgdorferi ospC types in avian and mammalian wildlife. Infect Genet Evol (2013) 0.85
Inferring epitopes of a polymorphic antigen amidst broadly cross-reactive antibodies using protein microarrays: a study of OspC proteins of Borrelia burgdorferi. PLoS One (2013) 0.84
Evolutionary Aspects of Emerging Lyme Disease in Canada. Appl Environ Microbiol (2015) 0.83
Lyme disease risk not amplified in a species-poor vertebrate community: similar Borrelia burgdorferi tick infection prevalence and OspC genotype frequencies. Infect Genet Evol (2014) 0.83
Blocking pathogen transmission at the source: reservoir targeted OspA-based vaccines against Borrelia burgdorferi. Front Cell Infect Microbiol (2014) 0.83
Evidence for strain-specific immunity in patients treated for early lyme disease. Infect Immun (2014) 0.82
The Western progression of lyme disease: infectious and Nonclonal Borrelia burgdorferi Sensu Lato populations in Grand Forks County, North Dakota. Appl Environ Microbiol (2014) 0.81
Molecular Typing of Borrelia burgdorferi. Curr Protoc Microbiol (2014) 0.80
Identification of Borrelia burgdorferi ospC genotypes in host tissue and feeding ticks by terminal restriction fragment length polymorphisms. Appl Environ Microbiol (2012) 0.80
Borrelia burgdorferi Keeps Moving and Carries on: A Review of Borrelial Dissemination and Invasion. Front Immunol (2017) 0.80
Evolution and population genomics of the Lyme borreliosis pathogen, Borrelia burgdorferi. Trends Genet (2015) 0.79
Detection of established virulence genes and plasmids to differentiate Borrelia burgdorferi strains. Infect Immun (2012) 0.79
An inverted repeat in the ospC operator is required for induction in Borrelia burgdorferi. PLoS One (2013) 0.78
Evolutionary genomics of Borrelia burgdorferi sensu lato: findings, hypotheses, and the rise of hybrids. Infect Genet Evol (2014) 0.78
Phylogenomic identification of regulatory sequences in bacteria: an analysis of statistical power and an application to Borrelia burgdorferi sensu lato. MBio (2015) 0.78
Public health impact of strain specific immunity to Borrelia burgdorferi. BMC Infect Dis (2015) 0.78
Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production. J Immunol (2014) 0.77
Evidence for Host-Genotype Associations of Borrelia burgdorferi Sensu Stricto. PLoS One (2016) 0.77
Multiple independent transmission cycles of a tick-borne pathogen within a local host community. Sci Rep (2016) 0.76
Invasive potential of Borrelia burgdorferi sensu stricto ospC type L strains increases the possible disease risk to humans in the regions of their distribution. Parasit Vectors (2014) 0.76
Population and Evolutionary Genomics of Amblyomma americanum, an Expanding Arthropod Disease Vector. Genome Biol Evol (2016) 0.76
Influences of Host Community Characteristics on Borrelia burgdorferi Infection Prevalence in Blacklegged Ticks. PLoS One (2017) 0.75
The ecology of infectious disease: effects of host diversity and community composition on Lyme disease risk. Proc Natl Acad Sci U S A (2003) 5.01
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals. Proc Natl Acad Sci U S A (2004) 3.84
Genetic diversity of ospC in a local population of Borrelia burgdorferi sensu stricto. Genetics (1999) 3.46
Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans. Infect Immun (1999) 3.41
ospC diversity in Borrelia burgdorferi: different hosts are different niches. Genetics (2004) 2.97
Geographic uniformity of the Lyme disease spirochete (Borrelia burgdorferi) and its shared history with tick vector (Ixodes scapularis) in the Northeastern United States. Genetics (2002) 2.92
Association of specific subtypes of Borrelia burgdorferi with hematogenous dissemination in early Lyme disease. J Infect Dis (1999) 2.64
Genetic diversity of Borrelia burgdorferi in lyme disease patients as determined by culture versus direct PCR with clinical specimens. J Clin Microbiol (1999) 2.35
The implications of a low rate of horizontal transfer in Borrelia. Trends Microbiol (2001) 2.34
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Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing. Proc Natl Acad Sci U S A (2004) 1.82
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Epidemic spread of Lyme borreliosis, northeastern United States. Emerg Infect Dis (2006) 1.69
A population genetic study of Borrelia burgdorferi sensu stricto from eastern Long Island, New York, suggested frequency-dependent selection, gene flow and host adaptation. Hereditas (1997) 1.60
Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response. Infect Immun (2005) 1.55
Lyme disease--United States, 2001-2002. MMWR Morb Mortal Wkly Rep (2004) 1.55
Borrelia burgdorferi ospC heterogeneity among human and murine isolates from a defined region of northern Maryland and southern Pennsylvania: lack of correlation with invasive and noninvasive genotypes. J Clin Microbiol (2005) 1.46
Methods for evaluating Lyme disease risks using geographic information systems and geospatial analysis. J Med Entomol (1996) 1.46
Co-evolution of the outer surface protein C gene (ospC) and intraspecific lineages of Borrelia burgdorferi sensu stricto in the northeastern United States. Infect Genet Evol (2006) 1.39
Interaction and transmission of two Borrelia burgdorferi sensu stricto strains in a tick-rodent maintenance system. Appl Environ Microbiol (2004) 1.38
Genetic diversity among Borrelia strains determined by single-strand conformation polymorphism analysis of the ospC gene and its association with invasiveness. J Clin Microbiol (2003) 1.31
Infection with multiple strains of Borrelia burgdorferi sensu stricto in patients with Lyme disease. Arch Dermatol (1999) 1.19
A modest model explains the distribution and abundance of Borrelia burgdorferi strains. Am J Trop Med Hyg (2006) 1.16
Genetic diversity of Borrelia burgdorferi sensu stricto in Peromyscus leucopus, the primary reservoir of Lyme disease in a region of endemicity in southern Maryland. Appl Environ Microbiol (2006) 1.14
Ecology of Lyme disease. Conn Med (1989) 0.99
Lyme disease--United States, 1999. MMWR Morb Mortal Wkly Rep (2001) 0.96
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis (2006) 13.01
A critical appraisal of "chronic Lyme disease". N Engl J Med (2007) 7.84
Lyme borreliosis. Lancet (2011) 4.81
Diagnosis of lyme borreliosis. Clin Microbiol Rev (2005) 4.48
Duration of antibiotic therapy for early Lyme disease. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (2003) 3.96
Differentiation of reinfection from relapse in recurrent Lyme disease. N Engl J Med (2012) 3.79
Clinical characteristics and treatment outcome of early Lyme disease in patients with microbiologically confirmed erythema migrans. Ann Intern Med (2002) 3.41
Systemic symptoms without erythema migrans as the presenting picture of early Lyme disease. Am J Med (2003) 3.23
Subjective symptoms after treatment of early Lyme disease. Am J Med (2010) 3.22
Profiling of temperature-induced changes in Borrelia burgdorferi gene expression by using whole genome arrays. Infect Immun (2003) 3.19
Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosorbent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. J Infect Dis (2003) 3.18
Prospective clinical evaluation of patients from Missouri and New York with erythema migrans-like skin lesions. Clin Infect Dis (2005) 3.04
Antiscience and ethical concerns associated with advocacy of Lyme disease. Lancet Infect Dis (2011) 2.88
Common misconceptions about Lyme disease. Am J Med (2013) 2.84
Treatment trials for post-Lyme disease symptoms revisited. Am J Med (2013) 2.75
MLST of housekeeping genes captures geographic population structure and suggests a European origin of Borrelia burgdorferi. Proc Natl Acad Sci U S A (2008) 2.67
Anti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms. Brain Behav Immun (2010) 2.50
Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol (2007) 2.32
Borrelia burgdorferi genotype predicts the capacity for hematogenous dissemination during early Lyme disease. J Infect Dis (2008) 2.26
Southern Tick-Associated Rash Illness (STARI) in the North: STARI following a tick bite in Long Island, New York. Clin Infect Dis (2011) 2.19
Human Borrelia miyamotoi infection in the United States. N Engl J Med (2013) 2.11
Disease severity in a murine model of lyme borreliosis is associated with the genotype of the infecting Borrelia burgdorferi sensu stricto strain. J Infect Dis (2002) 1.97
Reinfection in patients with Lyme disease. Clin Infect Dis (2007) 1.81
Efficacy of antibiotic prophylaxis for the prevention of Lyme disease: an updated systematic review and meta-analysis. J Antimicrob Chemother (2010) 1.75
Persistent and relapsing babesiosis in immunocompromised patients. Clin Infect Dis (2008) 1.71
An outbreak of mycobacterial furunculosis associated with footbaths at a nail salon. N Engl J Med (2002) 1.69
Serologic markers of Lyme disease in children with autism. JAMA (2013) 1.67
Long-term follow-up of patients with culture-confirmed Lyme disease. Am J Med (2003) 1.62
Empiric antibiotic treatment of erythema migrans-like skin lesions as a function of geography: a clinical and cost effectiveness modeling study. Vector Borne Zoonotic Dis (2013) 1.59
Antibiotic treatment of animals infected with Borrelia burgdorferi. Clin Microbiol Rev (2009) 1.51
Chlorhexidine bathing to reduce central venous catheter-associated bloodstream infection: impact and sustainability. Am J Med (2012) 1.50
Electrical twitch-obtaining intramuscular stimulation in lower back pain: a pilot study. Am J Phys Med Rehabil (2004) 1.49
Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions. Mol Microbiol (2009) 1.45
Single-tier testing with the C6 peptide ELISA kit compared with two-tier testing for Lyme disease. Diagn Microbiol Infect Dis (2012) 1.45
Single-dose prophylaxis against Lyme disease. Lancet Infect Dis (2007) 1.45
Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients. J Clin Microbiol (2002) 1.45
Why has Borrelia burgdorferi not been transmitted by blood transfusion? Transfusion (2013) 1.42
Poly-ticks: Blue State versus Red State for Lyme disease. Lancet (2005) 1.42
Quantitative detection of Borrelia burgdorferi in 2-millimeter skin samples of erythema migrans lesions: correlation of results with clinical and laboratory findings. J Clin Microbiol (2002) 1.40
Interaction and transmission of two Borrelia burgdorferi sensu stricto strains in a tick-rodent maintenance system. Appl Environ Microbiol (2004) 1.38
Fitness variation of Borrelia burgdorferi sensu stricto strains in mice. Appl Environ Microbiol (2007) 1.36
Comparative genome hybridization reveals substantial variation among clinical isolates of Borrelia burgdorferi sensu stricto with different pathogenic properties. J Bacteriol (2006) 1.34
Linear and circular plasmid content in Borrelia burgdorferi clinical isolates. Infect Immun (2003) 1.33
Borrelia burgdorferi basic membrane proteins A and B participate in the genesis of Lyme arthritis. J Exp Med (2007) 1.29
Brief communication: hematogenous dissemination in early Lyme disease. Ann Intern Med (2005) 1.24
Babesiosis in Lower Hudson Valley, New York, USA. Emerg Infect Dis (2011) 1.24
Natural history of colonization with vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus, and resistant gram-negative bacilli among long-term-care facility residents. Infect Control Hosp Epidemiol (2003) 1.24
Improving the yield of blood cultures from patients with early Lyme disease. J Clin Microbiol (2011) 1.22
Emergence of resistance to azithromycin-atovaquone in immunocompromised patients with Babesia microti infection. Clin Infect Dis (2010) 1.20
Bartonella spp. transmission by ticks not established. Emerg Infect Dis (2010) 1.19
Epitope mapping of antibodies to VlsE protein of Borrelia burgdorferi in post-Lyme disease syndrome. Clin Immunol (2011) 1.18
Recognition of Borrelia burgdorferi, the Lyme disease spirochete, by TLR7 and TLR9 induces a type I IFN response by human immune cells. J Immunol (2009) 1.18
Borrelia burgdorferi gene expression profiling with membrane-based arrays. Methods Enzymol (2002) 1.16
Borrelia burgdorferi sensu stricto is clonal in patients with early Lyme borreliosis. Appl Environ Microbiol (2008) 1.16
2-tiered antibody testing for early and late Lyme disease using only an immunoglobulin G blot with the addition of a VlsE band as the second-tier test. Clin Infect Dis (2010) 1.15
Uncoordinated phylogeography of Borrelia burgdorferi and its tick vector, Ixodes scapularis. Evolution (2010) 1.15
Erythema migrans. Infect Dis Clin North Am (2008) 1.14
Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals. J Bacteriol (2009) 1.14
Impaired host defense to infection and Toll-like receptor 2-independent killing of Borrelia burgdorferi clinical isolates in TLR2-deficient C3H/HeJ mice. FEMS Microbiol Lett (2004) 1.13
Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States. Emerg Infect Dis (2014) 1.13
Comparative transcriptional profiling of Borrelia burgdorferi clinical isolates differing in capacities for hematogenous dissemination. Infect Immun (2005) 1.11
Seroprevalence of antibodies that react with Anaplasma phagocytophila, the agent of human granulocytic ehrlichiosis, in different populations in Westchester County, New York. J Clin Microbiol (2002) 1.11
A comparison of two treatment regimens of ceftriaxone in late Lyme disease. Wien Klin Wochenschr (2005) 1.10
Comparison of five diagnostic modalities for direct detection of Borrelia burgdorferi in patients with early Lyme disease. Diagn Microbiol Infect Dis (2012) 1.10
Microbiologic evaluation of patients from Missouri with erythema migrans. Clin Infect Dis (2005) 1.10
Anti-Borrelia burgdorferi antibody profile in post-Lyme disease syndrome. Clin Vaccine Immunol (2011) 1.09
Asymptomatic infection with Borrelia burgdorferi. Clin Infect Dis (2003) 1.08
Variations in Barbour-Stoenner-Kelly culture medium modulate infectivity and pathogenicity of Borrelia burgdorferi clinical isolates. Infect Immun (2004) 1.08
Impact of clinical variables on Borrelia burgdorferi-specific antibody seropositivity in acute-phase sera from patients in North America with culture-confirmed early Lyme disease. Clin Vaccine Immunol (2008) 1.08