Published in Traffic on March 17, 2009
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics (2011) 2.34
The trypanosome flagellar pocket. Nat Rev Microbiol (2009) 2.07
Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat. J Cell Biol (2011) 1.25
Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways. J Cell Sci (2011) 0.89
Life and times: synthesis, trafficking, and evolution of VSG. Trends Parasitol (2014) 0.88
Evolutionary analysis of the ENTH/ANTH/VHS protein superfamily reveals a coevolution between membrane trafficking and metabolism. BMC Genomics (2012) 0.88
Evidence for recycling of invariant surface transmembrane domain proteins in African trypanosomes. Eukaryot Cell (2012) 0.86
Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani. PLoS Pathog (2015) 0.86
ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis. J Cell Sci (2015) 0.86
The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase. J Cell Sci (2014) 0.85
The epsin protein family: coordinators of endocytosis and signaling. Biomol Concepts (2012) 0.85
Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners. Eukaryot Cell (2011) 0.83
A comparative analysis of trypanosomatid SNARE proteins. Parasitol Int (2013) 0.81
Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes. Parasitology (2012) 0.79
Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking. Mol Biol Cell (2015) 0.79
The ancient small GTPase Rab21 functions in intermediate endocytic steps in trypanosomes. Eukaryot Cell (2013) 0.78
Trypanosoma brucei brucei: endocytic recycling is important for mouse infectivity. Exp Parasitol (2011) 0.77
Phosphoinositides, kinases and adaptors coordinating endocytosis in Trypanosoma brucei. Commun Integr Biol (2016) 0.77
Novel insights on ENTH domain-containing proteins in apicomplexan parasites. Parasitol Res (2016) 0.76
Vacuolar protein sorting receptor in Giardia lamblia. PLoS One (2012) 0.76
Conservation and divergence within the clathrin interactome of Trypanosoma cruzi. Sci Rep (2016) 0.76
Transferrin: Endocytosis and Cell Signaling in Parasitic Protozoa. Biomed Res Int (2015) 0.76
Lineage-specific proteins essential for endocytosis in trypanosomes. J Cell Sci (2017) 0.75
Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin. Traffic (2017) 0.75
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science (2007) 4.89
Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic "supergroups". Proc Natl Acad Sci U S A (2009) 3.02
The fifth adaptor protein complex. PLoS Biol (2011) 2.94
The genome of Naegleria gruberi illuminates early eukaryotic versatility. Cell (2010) 2.93
High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature (2012) 2.55
Evolution of filamentous plant pathogens: gene exchange across eukaryotic kingdoms. Curr Biol (2006) 2.55
RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei. Mol Biochem Parasitol (2003) 2.55
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics (2011) 2.34
Pan genome of the phytoplankton Emiliania underpins its global distribution. Nature (2013) 2.26
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature (2012) 2.15
Clathrin-mediated endocytosis is essential in Trypanosoma brucei. EMBO J (2003) 2.11
Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage. Traffic (2008) 1.86
Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins. BMC Evol Biol (2007) 1.82
Evolution of the eukaryotic membrane-trafficking system: origin, tempo and mode. J Cell Sci (2007) 1.81
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics (2009) 1.74
The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages. BMC Genomics (2008) 1.56
Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8. Mol Biol Cell (2003) 1.53
Chromosome-wide analysis of gene function by RNA interference in the african trypanosome. Eukaryot Cell (2006) 1.47
Endocytosis of a glycosylphosphatidylinositol-anchored protein via clathrin-coated vesicles, sorting by default in endosomes, and exocytosis via RAB11-positive carriers. Mol Biol Cell (2003) 1.46
Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei. Biochem J (2003) 1.45
Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements. Eukaryot Cell (2006) 1.44
Molecular paleontology and complexity in the last eukaryotic common ancestor. Crit Rev Biochem Mol Biol (2013) 1.39
Phylogeny of endocytic components yields insight into the process of nonendosymbiotic organelle evolution. Proc Natl Acad Sci U S A (2008) 1.35
First and last ancestors: reconstructing evolution of the endomembrane system with ESCRTs, vesicle coat proteins, and nuclear pore complexes. Curr Opin Cell Biol (2009) 1.32
Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei. J Cell Sci (2011) 1.29
Differential endocytic functions of Trypanosoma brucei Rab5 isoforms reveal a glycosylphosphatidylinositol-specific endosomal pathway. J Biol Chem (2001) 1.29
Reconstructing the evolution of the endocytic system: insights from genomics and molecular cell biology. Adv Exp Med Biol (2007) 1.26
Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases. J Cell Sci (2012) 1.25
Activation of endocytosis as an adaptation to the mammalian host by trypanosomes. Eukaryot Cell (2007) 1.24
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species. Proc Natl Acad Sci U S A (2012) 1.22
Eukaryotic systematics: a user's guide for cell biologists and parasitologists. Parasitology (2011) 1.20
The ancient and widespread nature of the ER-mitochondria encounter structure. Mol Biol Evol (2013) 1.17
Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis. Mol Biochem Parasitol (2004) 1.15
Rab protein evolution and the history of the eukaryotic endomembrane system. Cell Mol Life Sci (2010) 1.15
Evolution of specificity in the eukaryotic endomembrane system. Int J Biochem Cell Biol (2008) 1.14
NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions. PLoS Biol (2012) 1.12
The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences. Trends Parasitol (2002) 1.12
Evolution of modular intraflagellar transport from a coatomer-like progenitor. Proc Natl Acad Sci U S A (2013) 1.11
TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J Biol Chem (2006) 1.11
The single dynamin-like protein of Trypanosoma brucei regulates mitochondrial division and is not required for endocytosis. J Biol Chem (2003) 1.11
A cell-surface phylome for African trypanosomes. PLoS Negl Trop Dis (2013) 1.09
The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system. Trends Parasitol (2002) 1.05
Ubiquitylation is required for degradation of transmembrane surface proteins in trypanosomes. Traffic (2008) 1.05
Rab4 is an essential regulator of lysosomal trafficking in trypanosomes. J Biol Chem (2004) 1.04
Implications of the new eukaryotic systematics for parasitologists. Parasitol Int (2007) 1.03
Cytoplasmic targeting signals in transmembrane invariant surface glycoproteins of trypanosomes. J Biol Chem (2004) 1.03
Ubiquitylation and developmental regulation of invariant surface protein expression in trypanosomes. Eukaryot Cell (2011) 1.03
Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids. Mol Phylogenet Evol (2013) 1.02
A bioinformatic analysis of the RAB genes of Trypanosoma brucei. Mol Biochem Parasitol (2005) 1.02
Developmental variation in Rab11-dependent trafficking in Trypanosoma brucei. Eukaryot Cell (2005) 1.02
High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog (2011) 1.01
Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis. Mol Biochem Parasitol (2005) 1.00
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet (2012) 1.00
Dileucine signal-dependent and AP-1-independent targeting of a lysosomal glycoprotein in Trypanosoma brucei. Mol Biochem Parasitol (2007) 0.99
Evolution and diversity of the Golgi body. FEBS Lett (2009) 0.99
Evolution and diversity of the Golgi. Cold Spring Harb Perspect Biol (2011) 0.99
Repeated secondary loss of adaptin complex genes in the Apicomplexa. Parasitol Int (2008) 0.98
ER-associated protein degradation is a common mechanism underpinning numerous monogenic diseases including Robinow syndrome. Hum Mol Genet (2005) 0.97
TbRAB1 and TbRAB2 mediate trafficking through the early secretory pathway of Trypanosoma brucei. Mol Biochem Parasitol (2004) 0.97
An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei. Mol Cell Biol (2005) 0.97
The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells. J Biol Chem (2003) 0.96
Proteomic analysis of clathrin interactions in trypanosomes reveals dynamic evolution of endocytosis. Traffic (2013) 0.95
Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0. J Cell Sci (2011) 0.95
An automated graphics tool for comparative genomics: the Coulson plot generator. BMC Bioinformatics (2013) 0.95
Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Mol Pharmacol (2012) 0.94
Ultrastructural description of Breviata anathema, n. gen., n. sp., the organism previously studied as "Mastigamoeba invertens". J Eukaryot Microbiol (2006) 0.94
Evolution of the karyopherin-β family of nucleocytoplasmic transport factors; ancient origins and continued specialization. PLoS One (2011) 0.93
Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors. J Cell Biol (2009) 0.93
The mitochondrial genome and a 60-kb nuclear DNA segment from Naegleria fowleri, the causative agent of primary amoebic meningoencephalitis. J Eukaryot Microbiol (2013) 0.92
ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases. J Biol Chem (2012) 0.91
Reconstructing the mosaic glycolytic pathway of the anaerobic eukaryote Monocercomonoides. Eukaryot Cell (2006) 0.90
Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite. Mol Biochem Parasitol (2002) 0.90
Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei. Mol Biochem Parasitol (2002) 0.89
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control. Cell Microbiol (2013) 0.89
Comparative analysis of plant genomes allows the definition of the "Phytolongins": a novel non-SNARE longin domain protein family. BMC Genomics (2009) 0.89
Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy. Trends Parasitol (2013) 0.89
Leishmania major: clathrin and adaptin complexes of an intra-cellular parasite. Exp Parasitol (2004) 0.89
Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways. J Cell Sci (2011) 0.89
Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery. Traffic (2013) 0.88
Arf3 is activated uniquely at the trans-Golgi network by brefeldin A-inhibited guanine nucleotide exchange factors. Mol Biol Cell (2010) 0.87
Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms. Exp Parasitol (2005) 0.87
The cloning of one putative octopamine receptor and two putative serotonin receptors from the tobacco hawkmoth, Manduca sexta. Insect Biochem Mol Biol (2006) 0.86
Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Mol Biol Cell (2013) 0.86
Evidence for recycling of invariant surface transmembrane domain proteins in African trypanosomes. Eukaryot Cell (2012) 0.86
Ancient complexity, opisthokont plasticity, and discovery of the 11th subfamily of Arf GAP proteins. Traffic (2013) 0.85
Comparative genomic analysis of multi-subunit tethering complexes demonstrates an ancient pan-eukaryotic complement and sculpting in Apicomplexa. PLoS One (2013) 0.85
Differential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools. PLoS One (2013) 0.84
The cell biology of the endocytic system from an evolutionary perspective. Cold Spring Harb Perspect Biol (2014) 0.84
Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners. Eukaryot Cell (2011) 0.83