Published in Biochim Biophys Acta on February 11, 2009
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Autophagy in lysosomal storage disorders. Autophagy (2012) 1.59
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Isoprenoids, small GTPases and Alzheimer's disease. Biochim Biophys Acta (2010) 0.98
Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4. J Neurosci (2011) 0.98
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NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa. Mol Biol Cell (2014) 0.89
Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2. J Lipid Res (2014) 0.88
Npc1 acting in neurons and glia is essential for the formation and maintenance of CNS myelin. PLoS Genet (2013) 0.86
Niemann-Pick type C1 patient-specific induced pluripotent stem cells display disease specific hallmarks. Orphanet J Rare Dis (2013) 0.85
Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum. Cell Microbiol (2012) 0.85
The pleiotropic roles of sphingolipid signaling in autophagy. Cell Death Dis (2014) 0.84
Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain. PLoS One (2013) 0.82
In vivo analysis of compound activity and mechanism of action using epistasis in Drosophila. J Chem Biol (2010) 0.81
Charcot-Marie-Tooth disease and intracellular traffic. Prog Neurobiol (2012) 0.81
A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing. Dev Cell (2016) 0.79
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ABCA1-dependent sterol release: sterol molecule specificity and potential membrane domain for HDL biogenesis. J Lipid Res (2015) 0.79
Evaluation of an anti-tumor necrosis factor therapeutic in a mouse model of Niemann-Pick C liver disease. PLoS One (2010) 0.78
Age and diet affect gene expression profiles in canine liver tissue. PLoS One (2010) 0.78
MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease. Biochim Biophys Acta (2016) 0.77
Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function. J Bioenerg Biomembr (2014) 0.77
Sphingolipids and mitochondrial function, lessons learned from yeast. Microb Cell (2014) 0.76
Cholesterol Flux Is Required for Endosomal Progression of African Swine Fever Virions during the Initial Establishment of Infection. J Virol (2015) 0.76
Influence of four polymorphisms in ABCA1 and PTGS2 genes on risk of Alzheimer's disease: a meta-analysis. Neurol Sci (2016) 0.76
Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein. PLoS One (2013) 0.76
Misexpression of the Niemann-Pick disease type C1 (NPC1)-like protein in Arabidopsis causes sphingolipid accumulation and reproductive defects. Planta (2015) 0.76
Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism. Sci Rep (2016) 0.76
Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase. J Lipid Res (2017) 0.75
Aberrant promoter methylation profile of Niemann-pick type C1 gene in cardiovascular disease. Iran Biomed J (2013) 0.75
Phosphatidylcholine: Greasing the Cholesterol Transport Machinery. Lipid Insights (2016) 0.75
Association between the rs1805081 polymorphism of Niemann-Pick type C1 gene and cardiovascular disease in a sample of an Iranian population. Biomed Rep (2016) 0.75
Early Hippocampal i-LTP and LOX-1 Overexpression Induced by Anoxia: A Potential Role in Neurodegeneration in NPC Mouse Model. Int J Mol Sci (2017) 0.75
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci Transl Med (2011) 1.95
Phosphatidylcholine biosynthesis and lipoprotein metabolism. Biochim Biophys Acta (2011) 1.53
Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects. J Biol Chem (2005) 1.48
Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures. J Biol Chem (2004) 1.45
Impaired ABCA1-dependent lipid efflux and hypoalphalipoproteinemia in human Niemann-Pick type C disease. J Biol Chem (2003) 1.40
Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons. J Neurochem (2002) 1.36
Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1. J Neurosci (2007) 1.33
Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation. J Biol Chem (2002) 1.25
Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice. J Biol Chem (2012) 1.22
Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology. J Biol Chem (2012) 1.19
Defective cholesterol trafficking in Niemann-Pick C-deficient cells. FEBS Lett (2010) 1.16
Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. Am J Pathol (2009) 1.12
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. J Lipid Res (2007) 1.09
Ero1alpha requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM). Cell Stress Chaperones (2010) 1.07
Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin. Curr Opin Lipidol (2011) 1.03
Physiological consequences of disruption of mammalian phospholipid biosynthetic genes. J Lipid Res (2008) 1.02
Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons. J Biol Chem (2002) 1.02
Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice. Biochim Biophys Acta (2006) 1.01
A choline-deficient diet in mice inhibits neither the CDP-choline pathway for phosphatidylcholine synthesis in hepatocytes nor apolipoprotein B secretion. J Biol Chem (2004) 1.00
Defining the importance of phosphatidylserine synthase 2 in mice. J Biol Chem (2002) 0.99
Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice. Biochem J (2005) 0.99
Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase Cgamma1 and inhibition of calcineurin. J Biol Chem (2009) 0.98
Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia. J Biol Chem (2005) 0.96
Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin. J Lipid Res (2014) 0.96
Defining the importance of phosphatidylserine synthase-1 (PSS1): unexpected viability of PSS1-deficient mice. J Biol Chem (2008) 0.95
Phosphatidylcholine biosynthesis via CTP:phosphocholine cytidylyltransferase 2 facilitates neurite outgrowth and branching. J Biol Chem (2007) 0.93
Lipid homeostasis and lipoprotein secretion in Niemann-Pick C1-deficient hepatocytes. J Biol Chem (2006) 0.93
Correction of apolipoprotein A-I-mediated lipid efflux and high density lipoprotein particle formation in human Niemann-Pick type C disease fibroblasts. J Biol Chem (2006) 0.92
Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins. Biochim Biophys Acta (2010) 0.91
The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals. J Lipid Res (2005) 0.90
Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease. Am J Pathol (2008) 0.88
Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2009) 0.88
Enhanced expression and activation of CTP:phosphocholine cytidylyltransferase beta2 during neurite outgrowth. J Biol Chem (2003) 0.85
A potential neuroprotective role of apolipoprotein E-containing lipoproteins through low density lipoprotein receptor-related protein 1 in normal tension glaucoma. J Biol Chem (2012) 0.84
Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro. Biochim Biophys Acta (2011) 0.83
Neuronal models for studying lipid metabolism and transport. Methods (2005) 0.81
N-Myc and SP regulate phosphatidylserine synthase-1 expression in brain and glial cells. J Biol Chem (2010) 0.77
Involvement of CTP:phosphocholine cytidylyltransferase-β2 in axonal phosphatidylcholine synthesis and branching of neurons. Biochim Biophys Acta (2011) 0.77
Methods for the study of lipid metabolism in neurons. Anal Biochem (2004) 0.76
Externalization of phosphatidylserine during apoptosis does not specifically require either isoform of phosphatidylserine synthase. Biochim Biophys Acta (2004) 0.75